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510(k) Data Aggregation

    K Number
    K172733
    Date Cleared
    2018-10-22

    (406 days)

    Product Code
    Regulation Number
    880.2910
    Reference & Predicate Devices
    Predicate For
    N/A
    Why did this record match?
    Reference Devices :

    K152680

    AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
    Intended Use

    TD-1035 Thermometer is a temperature detector which is intended to measure the body temperature on axillary region. The device is intended for population age of six months and above, which is designed for home use.

    Device Description

    TD-1035 Thermometer is a temperature detector which is intended to measure the body temperature on axillary region, and transmit data to personnel device via Bluetooth pairing. The design concept is equivalent to the predicate device, K152680. There are two modifications made to the subject device: (1) indication for use (2) an elastic band was added. The elastic band is designed for more suitable and comfortable wearing. Moreover, the detected sensor contacts user skin directly, which is located on the silicone belt. The parts that contact the user are: (1) elastic band (2) sensor head (3) silicone belt.

    AI/ML Overview

    The device in question is the TaiDoc TD-1035 Thermometer, intended for measuring body temperature in the axillary region for individuals aged six months and above, designed for home use.

    Here's an analysis of the acceptance criteria and the studies performed:

    1. Table of Acceptance Criteria and Reported Device Performance

    Test CategoryAttachmentStandardAcceptance CriteriaReported Device Performance
    SoftwareA1.1IEC 62304Safety and effectiveness of software meet the device's indications for use.PASS
    Electrical Safety & PerformanceA1.2IEC 60601-1Basic safety and essential performance of medical electrical equipment and systems.PASS
    A1.3IEC 60601-1-11Basic safety and essential performance of medical electrical equipment and systems for use in the home healthcare environment.PASS
    A1.4IEC 60601-1-2Maintain Essential Performance and Basic Safety of EMC requirements when exposed to electromagnetic disturbances.PASS
    Risk ManagementA2.1ISO 14971Acceptable level of risk established against risk criteria.Overall the risks are acceptable.
    General Performance - AccuracyA1.5ISO 80601-2-56Storage Test: Greatest calculated error (δ) should not be > 0.09°F (0.05°C) between 95.00°F to 100.40°F (35.00°C to 38.00°C), and not > 0.18°F (0.10°C) between 68.00°F to 94.98°F (20.00°C to 34.99°C) and 100.42°F to 113.00°F (38.01°C to 45.00°C).When error δ < 0.09°F (0.05°C) or < 0.18°F (0.10°C) PASS
    A1.6ISO 80601-2-56Mechanical Shock Test: Same accuracy criteria as the storage test.When error δ < 0.09°F (0.05°C) or < 0.18°F (0.10°C) PASS
    A1.7Display Temperature RangeAll measurements meet the manufacturer-claimed display temperature range (68°F (20°C) to 113°F (45°C)) and comply with ISO 80601-2-56:2009 minimum display range (95°F (35.0°C) to 107.6°F (42.0°C)).PASS (implicitly, as it states "All measurements meet...")
    A1.8Accuracy Test Report (Laboratory)A sample size of 80 measurements, with no single measurement error exceeding the allowable limit, provides a confidence of 99% that at least 95% of all measurements will meet the acceptable criteria (same δ criteria as A1.5).When error δ < 0.09°F (0.05°C) or < 0.18°F (0.10°C) PASS
    A1.9Operating Environment Test ReportMaximum errors in the operation environment range (41°F to 104°F (5°C to 40°C), 15% to 93% RH) must meet the accuracy requirements (δ < 0.09°F (0.05°C)).When error δ < 0.09°F (0.05°C) PASS
    A1.11Accuracy Test Report After Cleaning ProcedureSame accuracy criteria as the storage test, after performing the manufacturer's cleaning procedure.When error δ < 0.09°F (0.05°C) or < 0.18°F (0.10°C) PASS
    BiocompatibilityA1.12ISO 10993-1, -5, -10, -12Cytotoxicity Test: Cell viability not reduced to < 70% of reagent control extract. Skin Sensitization Test: Grades of 1 or greater in test group generally indicate sensitization (provided control animals have <1). Irritation Test: Calculated irritation score.Cytotoxicity Test: ≥95% cell viability PASS Skin Sensitization Test: No evidence of causing delayed dermal contact sensitization PASS Irritation Test: PII of the test article was zero PASS
    A1.13ISO 10993-1, -5, -10, -12(For Stainless Steel Cap) Same biocompatibility criteria as A1.12.PASS (Implied by overall biocompatibility results)
    A1.14ISO 10993-1, -5, -10, -12(For Elastic Band) Same biocompatibility criteria as A1.12.PASS (Implied by overall biocompatibility results)
    A1.15ISO 10993-1, -5, -10, -12(For Silicone Belt) Same biocompatibility criteria as A1.12.PASS (Implied by overall biocompatibility results)
    Clinical AccuracyA1.16ISO 80601-2-56Clinical accuracy verified by comparing device output with a reference device. Statistical analysis results for system accuracy of body temperature measurement in non-febrile and febrile groups (infants (6 months and above), children, adults, and elderly) must meet 95% limit of agreement criteria.The statistics analysis results have demonstrated that the system accuracy of body temperature measurement... were met the criteria of 95% limit of agreement and [remaining text cut off]

    2. Sample Size Used for the Test Set and Data Provenance

    • Laboratory Accuracy Test (A1.8): A sample size of 80 measurements was used.
    • Clinical Test (A1.16): The document mentions "non-febrile and febrile group of subjects, infants (6 months and above), children, adults and elderly," but does not specify the exact sample size for the clinical test set.
    • Data Provenance: The document does not explicitly state the country of origin for the data or whether the studies were retrospective or prospective. Given that TaiDoc Technology Corporation is based in Taiwan, it is likely the studies were conducted there. The nature of the performance tests (laboratory, mechanical, storage, operating environment) suggests prospective testing. The clinical trial would also typically be prospective.

    3. Number of Experts Used to Establish the Ground Truth for the Test Set and Qualifications of those Experts

    The document does not provide information on the number of experts or their qualifications for establishing ground truth, particularly for the clinical study. For temperature measurement, ground truth for clinical accuracy studies typically involves highly accurate reference thermometers or direct measurement of core body temperature by qualified medical professionals.

    4. Adjudication Method for the Test Set

    The document does not describe any adjudication method.

    5. If a Multi-Reader Multi-Case (MRMC) Comparative Effectiveness Study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

    Not applicable. This is a medical device (thermometer), not an AI-assisted diagnostic tool that involves human "readers" interpreting cases.

    6. If a Standalone (i.e., algorithm only without human-in-the-loop performance) was done

    This is a physical thermometer. The performance tests (A1.1 - A1.16) evaluate the device's inherent capabilities, which can be considered "standalone" as they assess the device's readings against established standards or reference measurements. There isn't an "algorithm only" in the sense of software interpreting medical images, but rather the device's internal processing of temperature signals.

    7. The Type of Ground Truth Used

    • Laboratory Accuracy Tests (A1.5, A1.6, A1.8, A1.9, A1.11): The acceptance criteria refer to "calculated error δ" against a known or reference temperature. This implies comparison against calibrated reference standards/devices in controlled laboratory environments.
    • Clinical Test (A1.16): The clinical accuracy is verified "by comparing its output with that of a reference device, which has a specified uncertainty for measuring true temperature." This strongly suggests the use of a highly accurate reference thermometer or method to establish the "true" body temperature for comparison.

    8. The Sample Size for the Training Set

    The document does not provide information on a "training set" as this is not an AI/machine learning device that typically involves distinct training data. The device's performance is based on its engineering design and calibration, not a learned model from a dataset.

    9. How the Ground Truth for the Training Set Was Established

    Not applicable, as there is no mention of a training set for an AI/machine learning model.

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