K Number
K172733
Date Cleared
2018-10-22

(406 days)

Product Code
Regulation Number
880.2910
Reference & Predicate Devices
Predicate For
N/A
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

TD-1035 Thermometer is a temperature detector which is intended to measure the body temperature on axillary region. The device is intended for population age of six months and above, which is designed for home use.

Device Description

TD-1035 Thermometer is a temperature detector which is intended to measure the body temperature on axillary region, and transmit data to personnel device via Bluetooth pairing. The design concept is equivalent to the predicate device, K152680. There are two modifications made to the subject device: (1) indication for use (2) an elastic band was added. The elastic band is designed for more suitable and comfortable wearing. Moreover, the detected sensor contacts user skin directly, which is located on the silicone belt. The parts that contact the user are: (1) elastic band (2) sensor head (3) silicone belt.

AI/ML Overview

The device in question is the TaiDoc TD-1035 Thermometer, intended for measuring body temperature in the axillary region for individuals aged six months and above, designed for home use.

Here's an analysis of the acceptance criteria and the studies performed:

1. Table of Acceptance Criteria and Reported Device Performance

Test CategoryAttachmentStandardAcceptance CriteriaReported Device Performance
SoftwareA1.1IEC 62304Safety and effectiveness of software meet the device's indications for use.PASS
Electrical Safety & PerformanceA1.2IEC 60601-1Basic safety and essential performance of medical electrical equipment and systems.PASS
A1.3IEC 60601-1-11Basic safety and essential performance of medical electrical equipment and systems for use in the home healthcare environment.PASS
A1.4IEC 60601-1-2Maintain Essential Performance and Basic Safety of EMC requirements when exposed to electromagnetic disturbances.PASS
Risk ManagementA2.1ISO 14971Acceptable level of risk established against risk criteria.Overall the risks are acceptable.
General Performance - AccuracyA1.5ISO 80601-2-56Storage Test: Greatest calculated error (δ) should not be > 0.09°F (0.05°C) between 95.00°F to 100.40°F (35.00°C to 38.00°C), and not > 0.18°F (0.10°C) between 68.00°F to 94.98°F (20.00°C to 34.99°C) and 100.42°F to 113.00°F (38.01°C to 45.00°C).When error δ < 0.09°F (0.05°C) or < 0.18°F (0.10°C) PASS
A1.6ISO 80601-2-56Mechanical Shock Test: Same accuracy criteria as the storage test.When error δ < 0.09°F (0.05°C) or < 0.18°F (0.10°C) PASS
A1.7Display Temperature RangeAll measurements meet the manufacturer-claimed display temperature range (68°F (20°C) to 113°F (45°C)) and comply with ISO 80601-2-56:2009 minimum display range (95°F (35.0°C) to 107.6°F (42.0°C)).PASS (implicitly, as it states "All measurements meet...")
A1.8Accuracy Test Report (Laboratory)A sample size of 80 measurements, with no single measurement error exceeding the allowable limit, provides a confidence of 99% that at least 95% of all measurements will meet the acceptable criteria (same δ criteria as A1.5).When error δ < 0.09°F (0.05°C) or < 0.18°F (0.10°C) PASS
A1.9Operating Environment Test ReportMaximum errors in the operation environment range (41°F to 104°F (5°C to 40°C), 15% to 93% RH) must meet the accuracy requirements (δ < 0.09°F (0.05°C)).When error δ < 0.09°F (0.05°C) PASS
A1.11Accuracy Test Report After Cleaning ProcedureSame accuracy criteria as the storage test, after performing the manufacturer's cleaning procedure.When error δ < 0.09°F (0.05°C) or < 0.18°F (0.10°C) PASS
BiocompatibilityA1.12ISO 10993-1, -5, -10, -12Cytotoxicity Test: Cell viability not reduced to < 70% of reagent control extract. Skin Sensitization Test: Grades of 1 or greater in test group generally indicate sensitization (provided control animals have <1). Irritation Test: Calculated irritation score.Cytotoxicity Test: ≥95% cell viability PASS Skin Sensitization Test: No evidence of causing delayed dermal contact sensitization PASS Irritation Test: PII of the test article was zero PASS
A1.13ISO 10993-1, -5, -10, -12(For Stainless Steel Cap) Same biocompatibility criteria as A1.12.PASS (Implied by overall biocompatibility results)
A1.14ISO 10993-1, -5, -10, -12(For Elastic Band) Same biocompatibility criteria as A1.12.PASS (Implied by overall biocompatibility results)
A1.15ISO 10993-1, -5, -10, -12(For Silicone Belt) Same biocompatibility criteria as A1.12.PASS (Implied by overall biocompatibility results)
Clinical AccuracyA1.16ISO 80601-2-56Clinical accuracy verified by comparing device output with a reference device. Statistical analysis results for system accuracy of body temperature measurement in non-febrile and febrile groups (infants (6 months and above), children, adults, and elderly) must meet 95% limit of agreement criteria.The statistics analysis results have demonstrated that the system accuracy of body temperature measurement... were met the criteria of 95% limit of agreement and [remaining text cut off]

2. Sample Size Used for the Test Set and Data Provenance

  • Laboratory Accuracy Test (A1.8): A sample size of 80 measurements was used.
  • Clinical Test (A1.16): The document mentions "non-febrile and febrile group of subjects, infants (6 months and above), children, adults and elderly," but does not specify the exact sample size for the clinical test set.
  • Data Provenance: The document does not explicitly state the country of origin for the data or whether the studies were retrospective or prospective. Given that TaiDoc Technology Corporation is based in Taiwan, it is likely the studies were conducted there. The nature of the performance tests (laboratory, mechanical, storage, operating environment) suggests prospective testing. The clinical trial would also typically be prospective.

3. Number of Experts Used to Establish the Ground Truth for the Test Set and Qualifications of those Experts

The document does not provide information on the number of experts or their qualifications for establishing ground truth, particularly for the clinical study. For temperature measurement, ground truth for clinical accuracy studies typically involves highly accurate reference thermometers or direct measurement of core body temperature by qualified medical professionals.

4. Adjudication Method for the Test Set

The document does not describe any adjudication method.

5. If a Multi-Reader Multi-Case (MRMC) Comparative Effectiveness Study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

Not applicable. This is a medical device (thermometer), not an AI-assisted diagnostic tool that involves human "readers" interpreting cases.

6. If a Standalone (i.e., algorithm only without human-in-the-loop performance) was done

This is a physical thermometer. The performance tests (A1.1 - A1.16) evaluate the device's inherent capabilities, which can be considered "standalone" as they assess the device's readings against established standards or reference measurements. There isn't an "algorithm only" in the sense of software interpreting medical images, but rather the device's internal processing of temperature signals.

7. The Type of Ground Truth Used

  • Laboratory Accuracy Tests (A1.5, A1.6, A1.8, A1.9, A1.11): The acceptance criteria refer to "calculated error δ" against a known or reference temperature. This implies comparison against calibrated reference standards/devices in controlled laboratory environments.
  • Clinical Test (A1.16): The clinical accuracy is verified "by comparing its output with that of a reference device, which has a specified uncertainty for measuring true temperature." This strongly suggests the use of a highly accurate reference thermometer or method to establish the "true" body temperature for comparison.

8. The Sample Size for the Training Set

The document does not provide information on a "training set" as this is not an AI/machine learning device that typically involves distinct training data. The device's performance is based on its engineering design and calibration, not a learned model from a dataset.

9. How the Ground Truth for the Training Set Was Established

Not applicable, as there is no mention of a training set for an AI/machine learning model.

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Image /page/0/Picture/0 description: The image shows the logo of the U.S. Food and Drug Administration (FDA). On the left is the Department of Health & Human Services logo. To the right of that is the FDA logo, which is a blue square with the letters "FDA" in white. To the right of the blue square is the text "U.S. FOOD & DRUG ADMINISTRATION" in blue.

October 22, 2018

TaiDoc Technology Corporation Sylvia Liu Regulatory Affairs Specialist B1-7F, No.127, Wugong 2nd Rd., Wugu District New Taipei City, 24888 Taiwan

Re: K172733

Trade/Device Name: TD-1035 Thermometer Regulation Number: 21 CFR 880.2910 Regulation Name: Clinical Electronic Thermometer Regulatory Class: Class II Product Code: FLL Dated: September 14, 2018 Received: September 18, 2018

Dear Sylvia Liu:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. Although this letter refers to your product as a device, please be aware that some cleared products may instead be combination products. The 510(k) Premarket Notification Database located at https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpmn/pmn.cfm identifies combination product submissions. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you, however, that device labeling must be truthful and not misleading.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part

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801); medical device reporting of medical device-related adverse events) (21 CFR 803) for devices or postmarketing safety reporting (21 CFR 4, Subpart B) for combination products (see https://www.fda.gov/CombinationProducts/GuidanceRegulatoryInformation/ucm597488.htm); good manufacturing practice requirements as set forth in the quality systems (OS) regulation (21 CFR Part 820) for devices or current good manufacturing practices (21 CFR 4, Subpart A) for combination products; and, if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21 CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to http://www.fda.gov/MedicalDevices/Safety/ReportaProblem/default.htm.

For comprehensive regulatory information about mediation-emitting products, including information about labeling regulations, please see Device Advice

(https://www.fda.gov/MedicalDevices/DeviceRegulationandGuidance/) and CDRH Learn (http://www.fda.gov/Training/CDRHLearn). Additionally, you may contact the Division of Industry and Consumer Education (DICE) to ask a question about a specific regulatory topic. See the DICE website (http://www.fda.gov/DICE) for more information or contact DICE by email (DICE@fda.hhs.gov) or phone (1-800-638-2041 or 301-796-7100).

Sincerely,

Alan M.
Stevens -S

for Tina Kiang, Ph.D. Acting Director Division of Anesthesiology, General Hospital, Respiratory, Infection Control, and Dental Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

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Indications for Use

510(k) Number (if known) K172733

Device Name TD-1035 Thermometer

Indications for Use (Describe)

TD-1035 Thermometer is a temperature detector which is intended to measure the body temperature on axillary region. The device is intended for population age of six months and above, which is designed for home use.

Type of Use (Select one or both, as applicable)
---------------------------------------------------

Prescription Use (Part 21 CFR 801 Subpart D)

|X | Over-The-Counter Use (21 CFR 801 Subpart C)

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Image /page/3/Picture/3 description: The image shows the logo for TaiDoc. The logo consists of the word "TaiDoc" in gray font, followed by three red hearts. Below the hearts is the website address "www.taidoc.com" in white font on a gray background.

9. 510(k) Summary

This summary of 510(k) information is being submitted in accordance with the requirements of 21 CFR 807.92.

The Assigned 510(k) number is: K172733

1. Submitter Information
Company Name:TaiDoc Technology Corporation
Contact Person:Sylvia Liu
Title:Regulatory Affairs Specialist
Address:B1-7F., No. 127, Wugong 2nd Rd., Wugu District, New TaipeiCity 24888, TAIWAN
Phone:+886-2-6625-8188 #6134
Fax:+886-2-6625-0288
E-mail:Sylvia.liu@taidoc.com.tw
Prepared Date:October 22, 2018
2. Device Name
Proprietary Name:TD-1035 Thermometer
Common Name:Electronic Thermometer
Product Code:FLL
Review Panel:General Hospital
Device Class:Class II
Regulation Number:21 CFR §880.2910
3. Predicate Device
Proprietary Name:TD-1035 Thermometer
510(K) no.K152680

4. Device Description

TD-1035 Thermometer is a temperature detector which is intended to measure the body temperature on axillary region, and transmit data to personnel device via Bluetooth pairing. The design concept is equivalent to the predicate device, K152680. There are two modifications made to the subject device: (1) indication for use (2) an elastic band was added. The elastic band is designed for more suitable and comfortable wearing. Moreover, the detected sensor contacts user skin directly, which is located on the silicone belt. The parts that contact the user are: (1) elastic band (2) sensor head (3) silicone belt.

Principle of Operation

As the Bluetooth (BT) signals the CPU to display the temperature measurement. The thermistor is the type of temperature sensor and the CPU is a control center to process the device function.

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Image /page/4/Picture/0 description: The image shows the logo for TaiDoc. The logo consists of the word "TaiDoc" in gray, with three red hearts below it. Below the hearts is the website address "www.taidoc.com" in white text on a gray background.

The operating principle is based on differential temperature sending the signal to CPU which gets the signal than processes it and calculates the results.

5. Indications for Use

TD-1035 Thermometer is a temperature detector which is intended to measure the body temperature on axillary region. The device is intended for population age of six months and above, which is designed for home use.

6. Technological Characteristics

The concept of design is same as predicate product, K152680. There are two modifications were made to the proposed device: (1) indication for use (2) an elastic band was added. The modifications are changing the indication for use for population age of six months and above, which Thermometer is used at home. Also, the elastic band is design for more suitable and comfortable wearing.

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Image /page/5/Picture/0 description: The image shows the logo for TaiDoc. The logo consists of the word "TaiDoc" in gray, with three red hearts underneath. Below the hearts is the website address "www.taidoc.com" in white text on a gray background.

Tel : +886-2-6625-8188 Fax : +886-2-6625-0288

Table of Specification Comparison

ItemPredicate deviceProposed deviceComparison
510K NumberK152680K172733
Indication for UseThe TD-1035 Thermometer device is athermometer intended for body temperaturemeasurement at axillary temperaturemeasurement site. The device is intended formeasurement in patients 12 years and older ina home use environment.TD-1035 Thermometer is a temperaturedetector which is intended to measure thebody temperature on axillary region. Thedevice is intended for population age ofsix months and above, which isdesigned for home use.Similarity
Population12 years and olderSix months and aboveDifference
IntendedEnvironmentHome useSame as the predicateSame
ItemPredicate deviceProposed deviceComparison
510K NumberK152680K172733
Principles of operationThe Temperature Monitor detects the bodytemperature by thermistor which providessignals to the microcontroller where signals areconverted into a digital temperature value thatdisplayed in LCD screen. The thermistor is as atemperature sensor and the microcontroller isused for signal processing. The basic operatingprinciple is that a change of thermistor causedby changes of temperature provides a signal tothe microcontroller which gets the signal thanprocesses it and calculates the results.Same as the predicateSame
General Functions
Low temperature display< 89.60°F (32.00°C): Display: Lo °F (Lo °C)Same as the predicateSame
High temperature display>109.40°F (43.00°C):Display: Hi °F (Hi °C)Same as the predicateSame
Measurement areaArmpitSame as the predicateSame
Measurement units°C or °FSame as the predicateSame
Power sourceone 3V CR2032 lithium batterySame as the predicateSame
Battery lifeApprox. 25 days (1 time measurement/day)Same as the predicateSame
BeeperNoneSame as the predicateSame
Operating condition41°F to 104°F (5°C to 40°C);15% to 93% R.H.Same as the predicateSame
ItemPredicate deviceProposed deviceComparison
510K NumberK152680K172733
Storage condition-13°F to 158°F (-25°C to 70°C);10% to 95%R.H.Same as the predicateSame
Data transmissionBluetoothSame as the predicateSame
Dimensions (mm)40.5 (L) x 27.5 (W) x 11.7 (H)Same as the predicateSame
Weight (g)18 gSame as the predicateSame
Outer casingOn/off button, LCD display, armbandSame as the predicateSame
Atmosphericpressure range700 hPa to 1060 hPaSame as the predicateSame
Operation altitude2000 mSame as the predicateSame
Expected service life3 yearsSame as the predicateSame
Type BF appliedpartType BF Applied partSame as the predicateSame
SafetyIEC 60601-1Same as the predicateSame
EMCIEC 60601-1-2Same as the predicateSame
HarmonizedstandardISO 80601-2-52:2009Same as the predicateSame
Water-resistanceIP22Same as the predicateSame
Material Description
Top and BottomCaseABSSame as the predicateSame
Battery CoverABSSame as the predicateSame
M-KeySiliconeSame as the predicateSame
LensPCSame as the predicateSame
Stainless Steel Cap(Patient Contact Part)SUS304Same as the predicateSame
Silicone Belt(Patient Contact Part)SiliconeSame as the predicateSame
ItemPredicate deviceProposed deviceComparison
510K NumberK152680K172733
Elastic Band(Patient Contact Part)NANylon & Polyester 190D/Polyester 230gDifference
Biocompatibility Information
DescriptionTD-1035 Thermometer detect the temperature by contact to user skin directly, which the contact time shall less than 24hours. A part of silicone belt which is connected with sensor, without cover of the elastic band, located on the back ondevice and contact to user skin directly.
StandardISO 10993-1ISO 10993-5ISO 10993-10ISO 10993-12
Patient ContactPartsStainless Steel Cap, Silicone beltStainless Steel Cap, Silicone belt, ElasticbandSimilarity
Patient Contact Material Information
Stainless Steel CapSUS 304Same as the predicateSame
Silicone BeltSiliconeSame as the predicateSame
Elastic BandNANylon & Polyester 190D/Polyester 230gDifference

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Image /page/6/Picture/0 description: The image contains the word "TaiDoc" in gray font. Below the word are three red hearts in a row. The hearts are all the same size and shape.

新北市24888五股區五工二路127號6樓 6F., No.127, Wugong 2nd Rd., Wugu Dist., New Taipei City 24888, Taiwan

Tel : +886-2-6625-8188 Fax : +886-2-6625-0288

www.taidoc.com

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Image /page/7/Picture/0 description: The image shows the word "TaiDoc" in gray font. Below the word are three red hearts in a row. The hearts are evenly spaced and appear to be a design element associated with the text above.

泰博科技股份有限公司 新北市24888五股區五工二路127號6樓 6F., No.127, Wugong 2nd Rd., Wugu Dist., TaiDoc Technology Corp. New Taipei City 24888, Taiwan

Tel : +886-2-6625-8188 Fax : +886-2-6625-0288

www.taidoc.com

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Image /page/8/Picture/0 description: The image shows the word "TaiDoc" in gray font. Below the word are three red hearts in a row. The hearts are evenly spaced and appear to be the same size.

Tel : +886-2-6625-8188 Fax : +886-2-6625-0288

www.taidoc.com

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Image /page/9/Picture/0 description: The image shows the logo for TaiDoc. The logo consists of the word "TaiDoc" in gray letters above three red hearts. Below the hearts is the website address "www.taidoc.com" in white letters on a gray background.

Tel · +886-7-6675

Discussion

The conceptual design of the subject device K172733 is similar with the predicate device K152680, which has the additional component of elastic band.

Considering the user individual circumstances which the predicate device (K152680) could cause the risk of uncomfortable wearing under the long-term effects of temperature monitoring because of the silicone belt has fixed holes size and holes number that are fewer armpit adjustment space. Thus, to modify this issue that the additional elastic band design of the proposal device( K172733) has more space for users to adjust the device wearing, and let the thermo-detector effectively contact the user skin. Additionally, the temperature measurement accuracy of the subject device K172733 have met the criteria of the ISO 80601-2-56 Medical electrical equipment -- Part 2-56: Particular requirements for basic safety and essential performance of clinical thermometers for body temperature measurement.

Also, each parts of the subject device materials passed the biocompatibility test. Furthermore, the clinical trials have demonstrated that the subject device has met the temperature measurement criteria of ISO 80601-2-56. Overall, the performance tests demonstrate the elastic band does not impact device performance.

Conclusions

The concept of design is similar to the predicate device. K152680, which is a detector to measure the body temperature on axillary region, and transmit data to personal device via Bluetooth pairing. There are two modifications were made to the subject device: (1) indication for use (2) an elastic band was added. The elastic band is design for more suitable and comfortable wearing. Moreover, the temperature sensor is still contacting the user skin directly, which is located on the silicone belt.

The material of elastic band has passed the biocompatibility test. Also, the arm girth of elastic band is adjustable for users to apply on the axillary, and more convenient for using on children by guardian. A part of the silicone belt, which is connected with sensor, without cover of the elastic band, located on the back of device and contact to user skin directly. Overall, the performance tests demonstrate that the elastic band does not impact device performance.

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Image /page/10/Picture/0 description: The image shows the logo for TaiDoc, a company that specializes in medical devices. The logo consists of the word "TaiDoc" in gray letters, followed by three red hearts. Below the hearts is the company's website address, "www.taidoc.com", also in gray letters. The background of the logo is white.

新北市24888五股區五工二路127號6樓 6F., No.127, Wugong 2nd Rd., Wugu Dist., New Taipei City 24888, Taiwan

Tel : +886-2-6625-8188 Fax : +886-2-6625-0288

7. Performance Data

AttachmentStandardTitleIntended UseAcceptance CriteriaResults
A1.1IEC62304Medical devicesoftware - Softwarelife cycle processesThis validation is to test for product byitself to verify software is safe forpatients using the medical device or not.The pass/fail criteria is toevaluate the safety andeffectiveness of softwareare met the device'sindication for use.PASS
A1.2IEC60601-1General requirementsfor basic safety andessential performanceThis study is to test for the basic safetyand essential performance of medicalelectrical equipment and medicalelectrical systems which are intended bytheir manufacturer for use.The pass/fail criteria is toevaluate the basic safetyand essential performanceof medical electricalequipment and medicalelectrical systems.PASS
A1.3IEC60601-1-11General requirementsfor basic safety andessentialperformance -Collateral Standard:Requirements formedical electricalequipment andmedical electricalsystems used in thehome healthcareenvironmentThis study is to evaluate to the basicsafety and essential performance ofmedical electrical equipment and medicalelectrical systems which are intended bytheir manufacturer for use in the homehealthcare environment, regardless ofwhether the medical electrical equipmentor medical electrical system is intendedfor use by a lay operator or by trainedhealthcare personnel.The pass/fail criteria is toevaluate the basic safetyand essential performanceof medical electricalequipment and medicalelectrical systems for usein the home healthcareenvironment.PASS
A1.4IEC60601-1-2EMC Test ReportIEC 60601-1-2:2014 applies to the basicsafety and essential performance ofMedical Equipment (ME) equipment andME systems in the presence ofelectromagnetic disturbances and toThe pass/fail criteria islimited to maintain theEssential Performanceand Basic Safety of EMCrequirements.PASS
electromagnetic disturbances emitted byme equipment and me systems.
A2.1ISO14971Risk ManagementReportThe failure of the function resulting inwrong analytical result which may haveserious impairment to the health of apatient may happen. Control measureswere taken to reduce the risk to asminimum as possible. Safety andeffectiveness of use about the system wasthen verified.The risk criteria wereestablished when settingthe context, the level ofrisk would against thiscriteria in order todetermine whether therisk is acceptable.Overallthe risksareacceptable

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Image /page/11/Picture/0 description: The image shows the logo for TaiDoc. The text "TaiDoc" is written in gray, with three red heart shapes underneath the text. The hearts are evenly spaced and aligned horizontally.

泰博科技股份有限公司 新北市24888五股區五工二路127號6樓 6F., No.127, Wugong 2nd Rd., Wugu Dist., TaiDoc Technology Corp. New Taipei City 24888, Taiwan

Tel : +886-2-6625-8188 Fax : +886-2-6625-0288

General Performance Test:

AttachmentStandardTitleIntended UseAcceptance CriteriaResults
A1.5ISO80601-2-56Storage TestReportThis report is intended toevaluate the accuracy ofThermometer after having beenstored or transported withinmanufacturer's claimed range.The pass/fail criteria is to simulate the worstcase of the transportation and the storageconditions of the device when exposing at --13°F and at 158°F environment.The greatest calculated error δ should notbe greater than 0.09°F (0.05°C) betweenthe measuring range from 95.00°F to100.40°F (35.00°C to 38.00°C). The greatest calculated error δ should notbe greater than 0.18°F (0.10°C) betweenthe measuring range from 68.00°F to 94.98°F (20.00°C to 34.99°C) and the measuringrange from 100.42°F to 113.00°F (38.01°C to 45.00°C).When errorδ<0.09°F(0.05°C) or<0.18°F(0.10°C)PASS
A1.6ISO80601-2-56MechanicalShock TestReportVerify the performance ofThermometer is complied withISO 80601-2-56:2009 afterThe greatest calculated error δ should notbe greater than 0.09°F (0.05°C) betweenthe measuring range from 95.00°F toWhen errorδ<0.09°F(0.05°C) or
mechanical shock.100.40°F (35.00°C to 38.00°C).➤ The greatest calculated error δ should notbe greater than 0.18°F (0.10°C) betweenthe measuring range from 68.00°F to 94.98°F (20.00°C to 34.99°C) and the measuringrange from 100.42°F to 113.00°F (38.01°C to 45.00°C).<0.18°F(0.10°C)PASS
A1.7DisplayTemperatureRangeVerify the measuring displayrange of Thermometer iscomplied with the manufacture-claimed display temperaturerange and the FDArecommended standard, ISO80601-2-56:2009, which has therequirement of covering theminimum display range from 95°F (35.0°C) to 107.6°F (42.0°C).All measurements meet the manufacture-claimed display temperature range which iscover the measuring range from 68°F (20°C) to113°F (45°C) and it is in accordance with therequirement of ISO 80601-2-56:2009 that theminimum display range shall cover from 95°F(35.0°C) to 107.6°F (42.0°C).TemperatureRangeDisplay
A1.8AccuracyTest ReportAssess the laboratory accuracyof Thermometer under referenceconditions.A sample-size of 80 measurements, with nosingle measurement error exceeding theallowable limit, provides a confidence of 99%that at least 95% of all measurement will meetthe acceptable criteria.When errorδ<0.09°F(0.05°C) or<0.18°F(0.10°C)PASS
A1.9OperatingEnvironmentTest ReportVerify the operatingenvironment of Thermometerthat met the accuracyrequirements when operated inan environment of 41°F to 104To evaluate the maximum errors in theoperation environment range of 41°F to 104°F(5°C to 40°C) and a relative humidity of 15% to93% noncondensing, the environment chamberswere used to create the prospective condition.When errorδ<0.09°F(0.05°C)PASS
www.taidoc.com
A1.11AccuracyTest ReportAfterCleaningProcedure°F (5°C to 40°C) and a relativehumidity of 15% to 93%noncondensing. The operatingenvironment of 41°F to 104°F(5°C to 40°C) and a relativehumidity of 15% to 93%noncondensing are compliedwith the requirement of ISO80601-2-56:2009 internationalstandard that an ambienttemperature operating rangeshould at least be from 15°C to35°C and a relative humidityrange of 15% to 85%noncondensing.This test is intended to evaluatethe accuracy of TD-1035Thermometer after performingcleaning procedure by themanufacturer instruction.Two temperatures of chamber were set asdescribed in the standard.The greatest calculated error δ should notbe greater than 0.09°F (0.05°C) betweenthe measuring range from 95.00°F to100.40°F (35.00°C to 38.00°C). The greatest calculated error δ should notbe greater than 0.18°F (0.10°C) betweenthe measuring range from 68.00°F to 94.98°F (20.00°C to 34.99°C) and the measuringrange from 100.42°F to 113.00°F (38.01°C to 45.00°C).When errorδ<0.09°F(0.05°C) or<0.18°F(0.10°C)PASS
AttachmentStandardTitleIntended UseAcceptance CriteriaResults
A1.12BiocompatibilityTest Report forThermometerWhen assessingmedical device, thesponsor shouldCytotoxicity Test:If cell viability is reduced to < 70%of the reagent control extract, aCytotoxicity Test:≥95% cell viabilityPASS
A1.13ISO 10993-1ISO 10993-5ISO 10993-10ISO 10993-12BiocompatibilityTest Report forStainless SteelCapspecifically state if themedical device doesnot result in any risk ofdirect or indirect tissue-cytotoxic potential exists.Skin Sensitization Test:Grades of 1 or greater observed inthe test group generally indicatedPASSSkin Sensitization Test:The test article extractsand the test article
A1.14BiocompatibilityTest Report forElastic Bandcontacting components.Thus, performing thebiocompatibility test tosensitization, provided that grades ofless than 1 were observed on thecontrol animals.showed no evidence ofcausing delayed dermalcontact sensitization.PASS
A1.15BiocompatibilityTest Report forSilicone beltindicate the safety ofdevice, which includeswith Cytotoxicity Test,Skin Sensitization Test,and Irritation Test.Irritation Test:For each rabbit, the irritation scorefor test area was calculated by addingtogether the scores of erythema andedema at each time point and dividethe sum by the total number ofobservation.Irritation Test:The Primary irritationindex (PII) of the testarticle was zero.PASS
A1.16ISO 80601-2-56Clinical TestReportThis study is intendedto evaluate if the safetyand effectiveness ofdevice consistentlymeet the requirementsof the intended use.Clinical Accuracy of a thermometeris verified by comparing its outputwith that of a reference device, whichhas a specified uncertainty formeasuring true temperature.The statistics analysisresults havedemonstrated that thesystem accuracy ofbody temperaturemeasurement in non-febrile and febrilegroup of subjects,infants (6months andabove), children, adultsand elderly were metthe criteria of 95% limitof agreement and

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新北市24888五股區五工二路127號6樓 6F., No.127, Wugong 2nd Rd., Wugu Dist., New Taipei City 24888, Taiwan

Tel : +886-2-6625-8188 Fax : +886-2-6625-0288

www.taidoc.com

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Image /page/13/Picture/0 description: The image shows the word "TaiDoc" in gray font. Below the word are three red hearts in a row. The hearts are evenly spaced and appear to be a part of the logo.

新北市24888五股區五工二路127號6樓 6F., No.127, Wugong 2nd Rd., Wugu Dist., New Taipei City 24888, Taiwan

Tel : +886-2-6625-8188 Fax : +886-2-6625-0288

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新北市24888五股區五工二路127號6樓 6F., No.127, Wugong 2nd Rd., Wugu Dist., New Taipei City 24888, Taiwan

Tel : +886-2-6625-8188 Fax : +886-2-6625-0288

Biocompatibility & Clinical Test Report

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8. Conclusions

The TD-1035 Thermometer has same test principle, similar product design and specifications with the predicate device. Based on the information provided in this submission, the TD-1035 Thermometer is substantially equivalent to the predicate device (K152680).

§ 880.2910 Clinical electronic thermometer.

(a)
Identification. A clinical electronic thermometer is a device used to measure the body temperature of a patient by means of a transducer coupled with an electronic signal amplification, conditioning, and display unit. The transducer may be in a detachable probe with or without a disposable cover.(b)
Classification. Class II (performance standards). The device is exempt from the premarket notification procedures in part 807, subpart E of this chapter, subject to the limitations in § 880.9 and the following conditions for exemption:(1) Device is not a clinical thermometer with telethermographic functions;
(2) Device is not a clinical thermometer with continuous temperature measurement functions; and
(3) Appropriate analysis and testing (such as that outlined in the currently FDA-recognized editions, as appropriate, of ISO 80601-2-56, “Medical electrical equipment—Part 2-56: Particular requirements for basic safety and essential performance of clinical thermometers for body temperature measurement,” or ASTM E1965, “Standard Specification for Infrared Thermometers for Intermittent Determination of Patient Temperature,” or ASTM E1112, “Standard Specification for Electronic Thermometer for Intermittent Determination of Patient Temperature,” or ASTM E1104, “Standard Specification for Clinical Thermometer Probe Covers and Sheaths”) must validate specifications and performance of the device.