K Number
K231395
Date Cleared
2023-10-18

(156 days)

Product Code
Regulation Number
872.3640
Panel
Dental
Predicate For
N/A
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

INNO SLA Submerged Narrow Implant System is intended for two-stage surgical procedures in the following situations and with the following clinical protocols:

  • The intended use for the 3.3mm, 3.5mm diameter INNO Sub Narrow Implant is limited to the replacement of maxillary lateral incisors and mandibular incisors.

  • Immediate placement in extraction situations with a partially or completely healed alveolar ridge.

  • It is intended for delayed loading.

Device Description

The INNO SLA Submerged Implant System offers the following components.

1 INNO SLA Submerged Narrow Fixture (Narrow) Ø 3.3 x 8.00, 10.00, 12.00, 14.00 mm Ø 3.5 x 8.00, 10.00, 12.00, 14.00 mm
2 Cover Screw (Narrow) Ø 2.84 x 5.0 mm Ø 3.23 x 6.0 mm Ø 3.62 x 7.0 mm
3 Healing Abutment (Narrow) Type 1 Ø3.5 x 6.7, 7.2, 9.2, 10.2, 11.2 mm
4 Healing Abutment (Narrow) Type 2 Ø 4.5 x 7, 9, 10, 11, 12, 14 mm
5 Cemented Abutment (Narrow) Ø 4.5 x 7.85, 8.85, 9.85, 10.85, 11.85, 12.85, 13.85, 14.85mm Ø 4.5 x 9.35, 10.35, 11.35, 12.35, 13.35 mm Ø 4.5 x 7.65, 8.65, 9.65, 10.65, 11.65, 13.65, 14.65 mm Ø 4.5 x 9.15, 10.15, 11.15, 12.15, 13.15 mm
6 Angulated Abutment (Narrow) Ø 4.5 x 11.85, 12.85, 13.85, 14.85 mm (15°, 25°)
7 Multi S Abutment Ø 4.5 x 5, 5.8, 6mm
8 Multi A Abutment Ø 4.5 x 6.42, 7.42, 8.42, 6.96, 7.96mm (15°,30°) – Hex type Ø 4.5 x 6.23, 7.22, 8.22, 6.76, 7.76mm (15,30°) – Non Hex type
9 Multi Hybrid Ti-Base Cylinder Ø 4.5 x 4.5mm
10 Abutment Screw (Narrow) Ø 2.25 x 10.2 mm Ø 1.95 x 8.7 mm
Ø 1.95 x 9.3 mm
12 Multi Cylinder Screw Ø 2.25 x 5 mm
13 Straight Abutment Ø 3.5 x 13.5, 14, 15, 16, 17 mm
14 Temporary Abutment Ø 4.5 x 10 mm
15 Multi Titanium Cylinder Ø 4.5 x 9 mm

AI/ML Overview

The provided document is a 510(k) premarket notification for a medical device (INNO SLA Submerged Narrow Implant System). This type of document focuses on demonstrating substantial equivalence to legally marketed predicate devices, not on proving clinical effectiveness or meeting specific performance acceptance criteria through a dedicated study.

Therefore, the document does not contain any information regarding:

  • Acceptance criteria in the traditional sense of a clinical or performance study with numerical targets for metrics like sensitivity, specificity, accuracy, etc.
  • The study that proves the device meets acceptance criteria (as no such study with performance metrics is presented).
  • Sample size used for the test set or data provenance.
  • Number of experts used to establish ground truth or their qualifications.
  • Adjudication method.
  • Multi-reader multi-case (MRMC) comparative effectiveness study.
  • Standalone (algorithm only) performance.
  • Ground truth type for a performance study.
  • Sample size for the training set.
  • How the ground truth for the training set was established.

Instead, the document focuses on demonstrating substantial equivalence through:

1. Performance Data (Non-Clinical):

The performance testing listed focuses on engineering and material characteristics, leveraging previous clearances and established standards.

  • Gamma radiation sterilization and shelf-life: Leveraged from Cowellmedi Co., Ltd.'s previous clearance K132242.
  • Steam sterilization of abutments: Leveraged from Cowellmedi Co., Ltd.'s previous clearance K201323.
  • Five-year shelf life and packaging: Leveraged from Cowellmedi Co., Ltd's previous clearance K132242.
  • SLA surface treatment: Leveraged from Cowellmedi Co., Ltd.'s previous clearance K132242.
  • Fatigue test in accordance with ISO 14801: This is an engineering test to ensure the mechanical integrity of the implant system. The document states: "We have performed the fatigue test to make sure the differences do not raise and the test result of the test supported substantial equivalence." However, no specific numerical acceptance criteria or results are provided in the summary.
  • Biocompatibility endpoints: Leveraged from Cowellmedi Co., Ltd.'s previous clearance K132242.
  • Non-clinical worst-case MRI review: Performed using scientific rationale and published literature to evaluate displacement force and torque.

2. Substantial Equivalence Discussion and Comparison Chart:

This section directly compares the subject device (INNO SLA Submerged Narrow Implant System) with various predicate and reference devices, highlighting similarities in:

  • Intended Use
  • Material (Titanium Grade 4 or Ti-6Al-4V ELI)
  • Principle of Operation
  • Design
  • Surface Treatment (SLA, TiN Coating)
  • Sterility (Gamma Sterilization, Non-sterile with terminal sterilization via moist heat/autoclave, End User Sterilization)
  • Shelf Life (5 years)

The document asserts that slight differences, such as in abutment size options or diameter ranges, do not affect substantial equivalence or raise concerns about safety or performance.

In summary, for a traditional clinical or AI/ML performance study as requested, all fields would be "Not Applicable" or "Not Provided" based on the content of this 510(k) summary. The "acceptance criteria" here are implicitly that the device performs equivalently to the listed predicates based on the non-clinical tests and functional comparisons detailed.

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Image /page/0/Picture/0 description: The image shows the logo of the U.S. Food and Drug Administration (FDA). On the left is the seal of the Department of Health & Human Services. To the right of the seal is the FDA logo, which consists of the letters "FDA" in a blue square, followed by the words "U.S. FOOD & DRUG" in blue, and the word "ADMINISTRATION" in a smaller font size below.

Cowellmedi Co., Ltd. % Priscilla Chung Regulatory Affairs Consultant LK Consulting Group USA, Inc. 18881 Von Karman Ave, Ste. 160 Irvine. California 92612

Re: K231395

Trade/Device Name: INNO SLA Submerged Narrow Implant System Regulation Number: 21 CFR 872.3640 Regulation Name: Endosseous Dental Implant Regulatory Class: Class II Product Code: DZE, NHA Dated: September 18, 2023 Received: September 21, 2023

Dear Priscilla Chung:

We have reviewed your section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (the Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. Although this letter refers to your product as a device, please be aware that some cleared products may instead be combination products. The 510(k) Premarket Notification Database available at https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpmn/pmn.cfm identifies combination product submissions. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you, however, that device labeling must be truthful and not misleading.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

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Additional information about changes that may require a new premarket notification are provided in the FDA guidance documents entitled "Deciding When to Submit a 510(k) for a Change to an Existing Device" (https://www.fda.gov/media/99812/download) and "Deciding When to Submit a 510(k) for a Software Change to an Existing Device" (https://www.fda.gov/media/99785/download).

Your device is also subject to, among other requirements, the Quality System (QS) regulation (21 CFR Part 820), which includes, but is not limited to, 21 CFR 820.30. Design controls; 21 CFR 820.90. Nonconforming product; and 21 CFR 820.100, Corrective and preventive action. Please note that regardless of whether a change requires premarket review, the QS regulation requires device manufacturers to review and approve changes to device design and production (21 CFR 820.30 and 21 CFR 820.70) and document changes and approvals in the device master record (21 CFR 820.181).

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); medical device reporting of medical device-related adverse events) (21 CFR Part 803) for devices or postmarketing safety reporting (21 CFR Part 4, Subpart B) for combination products (see https://www.fda.gov/combination-products/guidance-regulatory-information/postmarketing-safety-reportingcombination-products); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820) for devices or current good manufacturing practices (21 CFR Part 4, Subpart A) for combination products; and, if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR Parts 1000-1050.

Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21 CFR 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to https://www.fda.gov/medical-device-safety/medical-device-reportingmdr-how-report-medical-device-problems.

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For comprehensive regulatory information about medical devices and radiation-emitting products, including information about labeling regulations, please see Device Advice (https://www.fda.gov/medicaldevices/device-advice-comprehensive-regulatory-assistance) and CDRH Learn (https://www.fda.gov/training-and-continuing-education/cdrh-learn). Additionally, you may contact the Division of Industry and Consumer Education (DICE) to ask a question about a specific regulatory topic. See the DICE website (https://www.fda.gov/medical-device-advice-comprehensive-regulatoryassistance/contact-us-division-industry-and-consumer-education-dice) for more information or contact DICE by email (DICE@fda.hhs.gov) or phone (1-800-638-2041 or 301-796-7100).

Sincerely,

Andrew I. Steen -S

Andrew I. Steen Assistant Director DHT1B: Division of Dental and ENT Devices OHT1: Office of Ophthalmic, Anesthesia, Respiratory, ENT and Dental Devices Office of Product Evaluation and Quality Center for Devices and Radiological Health

Enclosure

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Indications for Use

510(k) Number (if known) K231395

Device Name

INNO SLA Submerged Narrow Implant System

Indications for Use (Describe)

INNO SLA Submerged Narrow Implant System is intended for two-stage surgical procedures in the following situations and with the following clinical protocols:

  • The intended use for the 3.3mm, 3.5mm diameter INNO Sub Narrow Implant is limited to the replacement of maxillary lateral incisors and mandibular incisors.

  • Immediate placement in extraction situations with a partially or completely healed alveolar ridge.

  • It is intended for delayed loading.

Type of Use (Select one or both, as applicable)
Prescription Use (Part 21 CFR 801 Subpart D) Over-The-Counter Use (21 CFR 801 Subpart C)

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510(k) Summary

(K231395)

This summary of 510(k)-safety and effectiveness information is being submitted in accordance with requirements of 21 CFR Part 807.92.

Date: ________________________________________________________________________________________________________________________________________________________________________

Applicant / Submitter: 1.

Cowellmedi Co., Ltd. 48, Hakgam-daero 221beon-gil, Sasang-gu, Busan, 46986, Republic of Korea Tel. + 82-51-314-2028

2. Submission Correspondent:

Priscilla Chung LK Consulting Group USA, Inc. 18881 Von Karman Ave STE 160 Irvine CA 92612 Fax: 714-409-3357 Phone: 714-202-5789 Email: juhee.c(@)lkconsultinggroup.com

3. Device:

Proprietary Name:INNO SLA Submerged Narrow Implant System
Common Name:Endosseous dental implant
Classification Name:Implant, Endosseous, Root-Form
Classification:Class II, 21 CFR 872.3640
Classification Product Code:DZE, NHA

4. Predicate Device:

  • · Primary Predicate Device: UF(II) Narrow Implant System (K161987) by Dio, Inc.

  • · Reference Device:

  • Straumann® Ø2.9 mm Bone Level Tapered Implants (K162890) by Straumann USA, LLC - Healing Abutment for INNO SLA Submerged Implant System (K132242) by Cowellmedi Co., Ltd.

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  • Angulated Abutment for INNO SLA Submerged Implant System (K201323) by Cowellmedi Co., Ltd.

  • IS-III active System (K181138) by Neobiotech Co., Ltd.

  • Paltop Narrow Implant (K210117) by Paltop Advanced Dental Solutions, Ltd

  • Superline (K160965) by Dentium Co., Ltd.

  • Oneplant Dental Implant System (K081748) by WARANTEC Implant Co., Ltd.

  • URIS OMNI Narrow System & Prosthetic (K200817) by TruAbutment Korea Co., Ltd.

  • Magicore Solid Abutment (K201981) by InnoBioSurg Co., Ltd.

  • Multi Unit Temporary Cylinder (K210903) by Neobiotech Co., Ltd

  • BTI Interna Narrow/Plus Dental Implant System UnicCa (K211952) by B.T.I. Biotechnology Institute, SL

Device Description: 5.

The INNO SLA Submerged Implant System offers the following components.

NoComponent
1INNO SLA Submerged Narrow Fixture (Narrow)Ø 3.3 x 8.00, 10.00, 12.00, 14.00 mmØ 3.5 x 8.00, 10.00, 12.00, 14.00 mm
2Cover Screw (Narrow)Ø 2.84 x 5.0 mmØ 3.23 x 6.0 mmØ 3.62 x 7.0 mm
3Healing Abutment (Narrow)Type 1Ø3.5 x 6.7, 7.2, 9.2, 10.2, 11.2 mm
4Healing Abutment (Narrow)Type 2Ø 4.5 x 7, 9, 10, 11, 12, 14 mm
5Cemented Abutment (Narrow)Ø 4.5 x 7.85, 8.85, 9.85, 10.85, 11.85, 12.85, 13.85, 14.85mmØ 4.5 x 9.35, 10.35, 11.35, 12.35, 13.35 mmØ 4.5 x 7.65, 8.65, 9.65, 10.65, 11.65, 13.65, 14.65 mmØ 4.5 x 9.15, 10.15, 11.15, 12.15, 13.15 mm
6Angulated Abutment (Narrow)Ø 4.5 x 11.85, 12.85, 13.85, 14.85 mm (15°, 25°)
7Multi S AbutmentØ 4.5 x 5, 5.8, 6mm
8Multi A AbutmentØ 4.5 x 6.42, 7.42, 8.42, 6.96, 7.96mm (15°,30°) – Hex typeØ 4.5 x 6.23, 7.22, 8.22, 6.76, 7.76mm (15,30°) – Non Hex type
9Multi Hybrid Ti-Base CylinderØ 4.5 x 4.5mm
10Abutment Screw (Narrow)Ø 2.25 x 10.2 mmØ 1.95 x 8.7 mm

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Ø 1.95 x 9.3 mm
12Multi Cylinder ScrewØ 2.25 x 5 mm
13Straight AbutmentØ 3.5 x 13.5, 14, 15, 16, 17 mm
14Temporary AbutmentØ 4.5 x 10 mm
15Multi Titanium CylinderØ 4.5 x 9 mm

દ. Indications for Use:

INNO SLA Submerged Narrow Implant System is intended for two-stage surgical procedures in the following situations and with the following clinical protocols:

  • The intended use for the 3.3mm, 3.5mm diameter INNO Sub Narrow Implant is limited to the replacement of maxillary lateral incisors and mandibular incisors.

  • Immediate placement in extraction sites and in situations with a partially or completely healed alveolar ridge.

  • It is intended for delayed loading.

Performance Data (Non-Clinical): 7.

The following tests were performed on the subject device and the test results support that the subject device is substantially equivalent to the predicate devices.

  • Cowellmedi Co., Ltd.'s own clearance K132242 was leveraged for the gamma radiation sterilization, and shelf-life of the dental implants, and K201323 was leveraged for the steam sterilization of the abutments.
  • Five-year shelf life and packaging were leveraged from Cowellmedi Co., Ltd's own ● previous clearance K132242.
  • Cowellmedi Co., Ltd.'s own previous clearance K132242 was leveraged for the SLA ● surface treatment.
  • Fatigue test in accordance with ISO 14801
  • The biocompatibility endpoints were leveraged from the Cowellmedi Co., Ltd.'s own ● previous clearance K132242
  • . Non-clinical worst-case MRI review was performed to evaluate the subject device components in the MRI environment using scientific rationale and published literature (e.g., Woods, Terry O., Jana G. Delfino, and Sunder Rajan, "Assessment of Magnetically Induced Displacement Force and Torque on Metal Alloys Used in Medical Devices." Journal of Testing and Evaluation 49.2 (2019): 783-795), based on the entire system including all variations (all compatible implant bodies, abutments, and fixation screws) and material composition. Rationale addressed parameters per the FDA guidance "Testing and Labeling Medical Devices for Safety in the Magnetic Resonance (MR) Environment," including magnetically induced displacement force and torque.

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8. Substantial Equivalence

Substantial Equivalence Discussion

The INNO SLA Submerged Narrow Implant ally equivalent to the predicate devices in terms of intended use and technical characteristics. They are made of the same material and have similar design. There are slight differences mostly in abutment size options, however, it is very minor not affecting substantial equivalence.

We have performed the fairgue test to make sure the differences do not raise and the test result of the test supported substantial equivalence.

Based on the information and test results provided that the subject device is substantially equivalent to the predicate devices.

Comparison Chart

Subject DevicePredicate DeviceReference Device
510(k) NumberK231395K161987K211952
Device NameINNO SLA Submerged Narrow ImplantSystem - FixtureUF(II) Narrow Implant SystemBTI Interna Narrow/Plus Dental ImplantSystem UnicCa ®
ManufacturerCowellmedi Co., Ltd.DioB.T.I. Biotechnology Institute, SL.
Indications forUseThe INNO SLA Submerged NarrowImplant System is intended for two stagesurgical procedures in the followingsituations and with the following clinicalprotocols:-The intended use for the 3.3mm, 3.5mmdiameter Narrow Implant is limited to thereplacement of maxillary lateral incisorsand mandibular incisors.- Immediate placement in extraction sitesand in situations with a partially orcompletely healed alveolar ridge.-It is intended for delayed loading.The UF(II) Narrow Implant System isintended for two stage surgical proceduresin the following situations and with thefollowing clinical protocols:-The intended use for the 3.0mm, 3.3mmdiameter UF(II) Narrow Implant is limitedto the replacement of maxillary lateralincisors and mandibular incisors.- Immediate placement in extraction sitesand in situations with a partially orcompletely healed alveolar ridge.-It is intended for delayed loading.The BTI Dental Implant System UnicCa®for oral implant surgery is to be used forthe partial or total replacement of teeth inedentulate patients. Once attached to thebone, the implants act as an anchor forvarious fixed or removableprosthetic solutions that can be used toimprove or restore a patient's masticationfunction.Tiny® 3.0 UnicCa® implants shall be usedonly to replace maxillary lateral incisorsand mandibular lateral and central incisors.Immediate loading is recommended whenthere is good primary stability and anappropriate occlusal load.

Fixture ●

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DesignImage: Dental ImplantImage: Dental ImplantImage: Dental Implant
Diameter3.3. 3.5 mm3.0, 3.3mm3.3/3.5/3.75/4.0/4.25/4.75
Lengths(mm)8, 10, 12, 14mm8.5, 10, 11.5, 13, 15mm5.5/6.5/7.5/8.5/10/11.5/13/15
ConnectionInterfaceInternal HexInternal HexInternal HexNon - Submerged
Surface treatmentSLASLACalcium surface treatment
SterilityGamma SterilizationGamma SterilizationGamma Sterilization
MaterialTitanium Grade 4Titanium Grade 4Titanium Grade 4
Principle ofoperationThis product is a root-type fixture which isinserted in the alveolar bone. It replaces thefunctions of the missing teeth as a dentalimplant fixture.This product is a root-type fixture which isinserted in the alveolar bone. It replaces thefunctions of the missing teeth as a dentalimplant fixture.This product is a root-type fixture which isinserted in the alveolar bone. It replaces thefunctions of the missing teeth as a dentalimplant fixture.
Shelf Life5 years5 years5 years
Substantial Equivalence Discussion
The subject device has the same intended use, material, principle of operation, and design as the predicate devices. We identified a reference device(K211952) which covers the fixture size range of the subject device.

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• Healing Abutment (Type 1)

Subject DevicePredicate Device
510(k) NumberK231395K162890
Device NameHealing Abutment forINNO SLA Submerged Narrow ImplantSystemStraumann® Ø2.9 mm Bone Level TaperedImplants
ManufacturerCowellmedi Co., Ltd.Straumann USA, LLC
AppearanceImage: Healing AbutmentImage: Closure Caps and Healing Abutments
Diameter3.5 mmClosure Cap:Ø2.4 mmHealing Abutments:3.3/4.3 mm3.55/4.86 mm3.6/5.0 mm
Post Height1, 2mm-
Gingival Height0.5, 1, 2, 3, 4mmClosure Cap:0.5 mmHealing Abutments:2.0, 3.5, 5.0 and 6.5 mm
ConnectionInterfaceHex, Non-hex-
Surface treatmentN/AN/A
SterilityNon-sterile; intended for terminalsterilization via moist heat(autoclave)Non-sterile; intended for terminalsterilization via moist heat(autoclave)
Angulation
MaterialTi-6Al-4V ELITi-6Al-4V ELI
Principle ofoperationThe intended use is to protect the innerconfiguration of the implant and maintain,stabilize and form the soft tissue during thehealing process.The intended use is to protect the innerconfiguration of the implant and maintain,stabilize and form the soft tissue during thehealing process.
Substantial Equivalence Discussion
The subject device has the same intended use, material, and principle of operation as the predicate device.
The design is slightly different but that does not raise a question in safety or performance.

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Healing Abutment (Type 2) •

Subject DevicePredicate Device
510(k) NumberK231395K132242
Device NameHealing Abutment forINNO SLA Submerged Narrow ImplantSystemHealing Abutment forINNO SLA Submerged Implant System
ManufacturerCowellmedi Co., Ltd.Cowellmedi Co., Ltd.
AppearanceImage: Subject Device AppearanceImage: Predicate Device Appearance
Diameter4.5 mm4.1, 4.5, 4.9, 5.5, 5.95, 6.5mm
Post Height1, 2mm2, 3, 4, 5, 6, 7, 9mm
Gingival Height1, 2, 3, 4, 5, 7mm1, 2, 3, 4, 5, 7mm
ConnectionInterfaceHex, Non-hexHex, Non-hex
Surface treatmentN/AN/A
SterilityNon-sterile; intended for terminalsterilization via moist heat(autoclave)Non-sterile; intended for terminalsterilization via moist heat(autoclave)
Angulation
MaterialTi-6Al-4V ELITi-6Al-4V ELI
Principle ofoperationThis product is a superstructure which isconnects with the fixtures. It replaces thefunctions of the missing teeth as a dentalabutment.This product is a superstructure which isconnects with the fixtures using theAbutment Screw. It replaces the functions ofthe missing teeth as a dental abutment.
Substantial Equivalence Discussion
The subject device has the same intended use, material, principle of operation, and design as the predicatedevice. The wider range is to meet each patient needs and does not raise an issue in performance or safety sincethe size difference is minor.
• Angulated Abutment
Subject DevicePredicate Device
510(k) NumberK231395K201323
Device NameAngulated Abutment forINNO SLA Submerged Narrow ImplantSystemAngulated Abutment forINNO SLA Submerged Implant System
ManufacturerCowellmedi Co., Ltd.Cowellmedi Co., Ltd.
AppearanceImage: Angulated AbutmentImage: Angulated Abutment
Diameter4.5mm4.5mm
Post Height8mm5, 8mm
Gingival Height1, 2, 3, 4mm1, 2, 3, 4mm
ConnectionInterfaceHex, Non-HexHex, Non-Hex
Surface treatmentTiN CoatingTiN Coating
SterilityNon-sterile; intended for terminalsterilization via moist heat(autoclave)Non-sterile; intended for terminalsterilization via moist heat(autoclave)
Angulation15°, 25°15°, 25°
MaterialTi-6Al-4V ELITi-6Al-4V ELI
Principle ofoperationThis product is a superstructure which isconnects with the fixtures. It replaces theThis product is a superstructure which isconnects with the fixtures using the

Angulated Abutment .

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functions of the missing teeth as a dentalAbutment Screw. It replaces the functions of
abutment.the missing teeth as a dental abutment.
Substantial Equivalence Discussion
The subject device has the same intended use, material, principle of operation, surface treatment, and design asthe predicate device. The size range of the predicate device encompasses that of the subject device.

Cemented Abutment ●

Subject DevicePredicate Device
510(k) NumberK231395K181138
Device NameCemented Abutment forINNO SLA Submerged Narrow ImplantSystemIS-III active System
ManufacturerCowellmedi Co., Ltd.Neobiotech Co., Ltd
AppearanceImage: Predicate Device
Diameter4.5mm4.5/5.2/5.7/6.5mm
Post4/5.5/7mm4.0/4.5/5.5/7.0/8.0mm
ConnectionInterfaceHex, Non-HexHex, Non-Hex
Surface treatmentTiN CoatingTiN Coating
SterilityNon-sterile; intended for terminalsterilization via moist heat(autoclave)Non-sterile; intended for terminalsterilization via moist heat(autoclave)
Angulation
MaterialTi-6Al-4V ELITi-6Al-4V ELI
Principle ofoperationIt is indicated for screw-retained single toothor cement retained single tooth and bridgerestorations.It is indicated for screw-retained single toothor cement retained single tooth and bridgerestorations.
Substantial Equivalence Discussion
The subject device has the same intended use, material, principle of operation, surface treatment, and design asthe predicate device. The size range of the predicate device encompasses that of the subject device.

Multi S Abutment ●

Subject DevicePredicate Device
510(k) NumberK231395K210117
Device NameMulti S Abutment forINNO SLA Submerged Narrow ImplantSystemPaltop Narrow Implant
ManufacturerCowellmedi Co., Ltd.Paltop Advanced Dental Solutions, Ltd
AppearanceImage: Multi S Abutment for INNO SLA Submerged Narrow Implant SystemImage: Paltop Narrow Implant
Diameter4.5mm4.5mm
G/H1/2/3/4/5mm1/2/3/4/5mm

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ConnectionInterfaceHexHex
Surface treatmentTiN Coating-
SterilityNon-sterile; intended for terminalsterilization via moist heat(autoclave)Non-sterile; intended for terminalsterilization via moist heat(autoclave)
Angulation
MaterialTi-6Al-4V ELITi-6Al-4V ELI
Principle ofoperationIt is indicated for screw-retained single toothor cement retained single tooth and bridgerestorations.It is indicated for screw-retained single toothor cement retained single tooth and bridgerestorations.
Substantial Equivalence DiscussionThe subject device (Multi S Abutment) is substantially equivalent to the predicate device (Multi Abutment,K161689). The subject device and the predicate device have the same internal implant interface connections,are made of Ti-6Al-4V ELI. There is a slight difference in surface treatment, but it does not raise a concern insafety or effectiveness based on our biocompatibility evaluations.

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Multi A Abutment ●

Subject DevicePredicate Device
510(k) NumberK160965
Device NameMulti A Abutment forINNO SLA Submerged Narrow ImplantSystemSuperline
ManufacturerCowellmedi Co., Ltd.Dentium Co., Ltd
AppearanceImage: Multi A AbutmentImage: Superline
Diameter4.5mm4.5mm
G/H2,3,4mm1/1.5/2/2.5/3/3.5/4/4.5/5/5.5mm
Interfaceabutment-implantInternalInternal
Surface treatmentTiN CoatingTin Coating
SterilityNon-sterile; intended for terminalsterilization via moist heat(autoclave)Non-sterile; intended for terminalsterilization via moist heat(autoclave)
Angulation15°, 30°15°,20°, 30°
MaterialTi-6Al-4V ELITi-6Al-4V ELI
Principle ofoperationIt is indicated for screw-retained single toothor cement retained single tooth and bridgerestorations.It is indicated for screw-retained singletooth or cement retained single tooth andbridge restorations.
Substantial Equivalence Discussion
The subject device (Multi A Abutment) is substantially equivalent to the predicate device. The subject device andthe predicate device have the same internal implant interface, are made of Ti-6Al-4V ELI. The angulation

the predicate device have the same internal implant interface connections, are made of Ti-6Al-4V ELI. The size
of the predicate device encompasses that of the subject device.

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• Multi Hybrid Ti Cylinder

Subject DevicePredicate Device
510(k) NumberK231395K081748
Device NameMulti Hybrid Ti CylinderOneplant Dental Implant System
ManufacturerCowellmedi Co., Ltd.WARANTEC Implant Co., Ltd
AppearanceImage: Multi Hybrid Ti CylinderImage: Oneplant Dental Implant System
Diameter4.5mmHex/Non-Hex: 4.5/5.5mm
Post4.5mm-
SterilityEnd User SterilizationEnd User Sterilization
MaterialTi-6Al-4V ELITitanium Alloy
Principle of operationMulti Hybrid Ti Cylinder is intended for use in partially or fully edentulous mandibles and maxillae to support for single or multiple-unit restorations such as cemented retained, or over denture restorations and terminal or intermediate abutment support for fixed bridgework.ONEPLANT is designed for use in dental implant surgery. These are intended for use in partially or fully edentulous mandibles and maxillae to support for single or multiple-unit restorations such as cemented retained, or over denture restorations and terminal or intermediate abutment support for fixed bridgework.
Substantial Equivalence Discussion
The subject device has the same intended use, material, principle of operation, and similar design as the predicate device.

• Multi Cylinder Screw

Subject DevicePredicate Device
510(k) NumberK231395K200817
Device NameMulti Cylinder ScrewURIS OMNI Narrow System & Prosthetic
ManufacturerCowellmedi Co., Ltd.TruAbutment Korea Co., Ltd
AppearanceImage: Multi Cylinder ScrewImage: URIS OMNI Narrow System & Prosthetic
Diameter2.25mm1.6mm
Length5mm3.3 mm
SterilityEnd User SterilizationEnd User Sterilization
MaterialTi-6Al-4V ELI (ASTM F136)Ti-6Al-4V ELI (ASTM F136)
Principle ofoperationMulti-unit Cylinder Screw is apremanufactured prosthetic componentdirectly connected to the endosseous dentalMulti-unit Cylinder Screw is apremanufactured prosthetic componentdirectly connected to the endosseous dental

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implant and is intended for use as an aid inprosthetic rehabilitation.implant and is intended for use as an aid inprosthetic rehabilitation.
Substantial Equivalence Discussion
The subject device has the same intended use, material, principle of operation, and design as the predicatedevice. There is a slight difference in size, but it does not raise a concern in safety or effectiveness.
• Straight Abutment
Subject DevicePredicate Device
510(k) NumberK231395K201981
Device NameStraight AbutmentMagicore Solid Abutment
ManufacturerCowellmedi Co., Ltd.InnoBioSurg Co., Ltd.
AppearanceImage: Straight AbutmentImage: Magicore Solid Abutment
Diameter3.5mm3.5/3.86/4.3/4.6mm
Post8mm7.6/8.6/9.6/10.6/11.6 mm
SterilityEnd User SterilizationEnd User Sterilization
MaterialTi-6Al-4V ELI (ASTM F136)Ti-6Al-4V ELI (ASTM F136)
Principle ofoperationStraight Abutment is intended for use with adental implant to provide support forprosthetic restorations such as crowns,bridges, or overdentures.Straight Abutment is intended for use with adental implant to provide support forprosthetic restorations such as crowns,bridges, or overdentures.
Substantial Equivalence Discussion
The subject device has the same intended use, material, principle of operation, and similar design as thepredicate device. The size range of the predicate device encompasses that of the subject device.

Temporary Abutment ●

Subject DevicePredicate Device
510(k) NumberK231395K181138
Device NameTemporary AbutmentIS-III active System
ManufacturerCowellmedi Co., Ltd.Neobiotech Co., Ltd
AppearanceImage: Subject Device AppearanceImage: Predicate Device Appearance
Diameter4.5mm4.5mm
Post10mm6.0/8.0/11.5 mm
SterilityEnd User SterilizationEnd User Sterilization
MaterialTi-6Al-4V ELI (ASTM F136)Ti-6Al-4V ELI (ASTM F136)
Principle of operationIt is dental Abutments designed to serve as atemporary dental prosthesis during thehealing process until a permanent crown ismade.It is dental Abutments designed to serve as atemporary dental prosthesis during thehealing process until a permanent crown ismade.
Substantial Equivalence Discussion

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The subject device has the same intended use, material, principle of operation, and similar design as the predicate device. The size range of the predicate device encompasses that of the subject device.

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Subject Device1st Predicate Device2nd Predicate Device
510(k) NumberK231395K210117K210903
Device NameMulti Titanium CylinderMulti-Unit CylinderMulti Unit Temporary Cylinder
ManufacturerCowellmedi Co., Ltd.Paltop Advanced Dental Solutions, LtdNeobiotech Co., Ltd
AppearanceImage: Subject DeviceImage: 1st Predicate DeviceImage: 2nd Predicate Device
Diameter4.5mm4.5mm4.8/6.0mm
Post9mm-11mm
Angle
SterilityEnd User SterilizationEnd User SterilizationEnd User Sterilization
MaterialTi-6Al-4V ELI (ASTM F136)Ti-6Al-4V ELI (ASTM F136)Ti-6Al-4V ELI (ASTM F136)
Principle ofoperationMulti Titanium Cylinder is designed toserve as a temporary dental prosthesisduring the healing process until apermanent bridges are made.-It is designed to serve as a temporarydental prosthesis during the healing processuntil a permanent bridges are made.
Duration of Use90 days-90 days
Substantial Equivalence Discussion
The subject device has the same diameter size as the first predicate device. The subject device has the same intended use, material, principle of operation,and similar design as the second predicate device.

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Conclusion: 9.

Based on the testing results, Cowellmedi Co., Ltd. concludes that the INNO SLA Submerged Narrow Implant System is substantially equivalent to the predicate devices.

§ 872.3640 Endosseous dental implant.

(a)
Identification. An endosseous dental implant is a prescription device made of a material such as titanium or titanium alloy that is intended to be surgically placed in the bone of the upper or lower jaw arches to provide support for prosthetic devices, such as artificial teeth, in order to restore a patient's chewing function.(b)
Classification. (1) Class II (special controls). The device is classified as class II if it is a root-form endosseous dental implant. The root-form endosseous dental implant is characterized by four geometrically distinct types: Basket, screw, solid cylinder, and hollow cylinder. The guidance document entitled “Class II Special Controls Guidance Document: Root-Form Endosseous Dental Implants and Endosseous Dental Implant Abutments” will serve as the special control. (See § 872.1(e) for the availability of this guidance document.)(2)
Classification. Class II (special controls). The device is classified as class II if it is a blade-form endosseous dental implant. The special controls for this device are:(i) The design characteristics of the device must ensure that the geometry and material composition are consistent with the intended use;
(ii) Mechanical performance (fatigue) testing under simulated physiological conditions to demonstrate maximum load (endurance limit) when the device is subjected to compressive and shear loads;
(iii) Corrosion testing under simulated physiological conditions to demonstrate corrosion potential of each metal or alloy, couple potential for an assembled dissimilar metal implant system, and corrosion rate for an assembled dissimilar metal implant system;
(iv) The device must be demonstrated to be biocompatible;
(v) Sterility testing must demonstrate the sterility of the device;
(vi) Performance testing to evaluate the compatibility of the device in a magnetic resonance (MR) environment;
(vii) Labeling must include a clear description of the technological features, how the device should be used in patients, detailed surgical protocol and restoration procedures, relevant precautions and warnings based on the clinical use of the device, and qualifications and training requirements for device users including technicians and clinicians;
(viii) Patient labeling must contain a description of how the device works, how the device is placed, how the patient needs to care for the implant, possible adverse events and how to report any complications; and
(ix) Documented clinical experience must demonstrate safe and effective use and capture any adverse events observed during clinical use.