K Number
K121059
Date Cleared
2012-08-07

(123 days)

Product Code
Regulation Number
890.5860
Reference & Predicate Devices
Predicate For
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

The indications for use of the proposed device are the same as those for the predicate devices.
Ultrasound therapy:

  • Relief of pain, muscle spasms and joint contractures
  • Relief of pain, muscle spasms and joint contractures that may be associated with:
    • Adhesive capsulitis
    • Bursitis with slight calcification
    • Myositis
    • Soft tissue injuries
    • Shortened tendons due to past injuries and scar tissues
  • Relief of pain, muscle spasms and joint contractures resulting from:
    • Capsular tightness
    • Capsular scarring
      Electrotherapy:
  • Relaxation of muscle spasm
  • Prevention or retardation of disuse atrophy
  • Increasing local blood circulation
  • Muscle re-education
  • Immediate post-surgical stimulation of calf muscles to prevent venous thrombosis
  • Maintaining or increasing range of motion
  • Symptomatic relief or management of chronic, intractable pain
  • Post-traumatic acute pain
  • Post-surgical acute pain
Device Description

The Soleoline has a clear contemporary color screen showing all parameters necessary for therapy as well as modem touch control. Individual program start configuration and clear, simple menu navigation make operation of the device easy and comfortable for users. 120 storage bins for individual program settings makes working with the Soleoline a lot easier. The compact design saves room in the practice and is highly suited for use in home visits. The combination of electrotherapy and ultrasound therapy in a single system enables the use of the established combination therapy. It is a prescription device administered to patients by a licensed healthcare provider in hospitals, post acute care facilities, nursing homes and outpatient clinics.
Soleoline is a device family consisting of Soleo Stim and Soleo SonoStim, Soleo Sono includes an ultrasound module, Soleo Stim includes a stimulation current therapy module and Soleo SonoStim includes a combination of a stimulation current module and an ultrasound module.
The stimulation current module is used for stimulation current therapy according to the standard medical practices. It offers multiple waveforms; Monophasic, High Voltage, Micro Current, Asymmetrical Biphasic, Interferential, Medium Frequency, Premodulated currents for nerve stimulation and muscle therapy for mono channel and dual channel operation. The regulated output of the current stimulation module may be chosen from Constant Current (CC) or Constant Voltage (CV).
The dual frequency ultrasound module (800kHz and 2.4MHz) offers two different size ultrasound heads, 1cm² and 5cm² and pulsed and continuous duty cycles.
At combination therapy (simultaneous procedure) the features for ultrasound can be used together with the different stimulation waveforms. All functions of the 0.8MHz and 2.4MHz ultrasound can be combined with the following waveforms:
Monophasic, High Voltage, Micro Current, Symmetrical Biphasic, Medium Frequency, Premodulated
The therapy menu helps the clinicians to assign the indications of each body region to the appropriate therapy program.

AI/ML Overview

The provided document is a 510(k) Summary for the Zimmer MedizinSysteme Soleoline device family. This type of submission is for demonstrating substantial equivalence to a legally marketed predicate device, rather than proving safety and efficacy from scratch through entirely novel clinical studies. Therefore, the information provided focuses on comparisons to existing devices and compliance with standards, rather than new studies with acceptance criteria and detailed performance metrics as one might find for a novel AI device.

Based on the provided text, here is an attempt to address the points, acknowledging the nature of a 510(k) summary:

1. A table of acceptance criteria and the reported device performance

The document doesn't present "acceptance criteria" in the typical sense of a novel device study (e.g., target sensitivity/specificity). Instead, substantial equivalence is demonstrated by showing that the new device (Soleoline) has the same intended use and similar technological characteristics as the predicate devices, and that any differences do not raise new questions of safety or effectiveness. The "reported device performance" is essentially a comparison of technical specifications against the predicate devices.

Here's a table summarizing key comparisons from the document, which implicitly serve as demonstration of equivalent performance to the established predicate devices:

Feature/ParameterAcceptance Criteria (Implied by Predicate Devices)Reported Device Performance (Zimmer Soleoline)
General
Intended UseSame as Predicate Devices (Ultrasonic diathermy, Powered muscle stimulator, etc.)Same as Predicate Devices (Ultrasonic diathermy, Powered muscle stimulator, Ultrasound and muscle stimulator)
Indications (Electrotherapy)Matched to Predicate Devices (Relaxation of muscle spasm, pain relief, etc.)Matched to Predicate Devices (Relaxation of muscle spasm, pain relief, etc.)
Indications (Ultrasound)Matched to Predicate Devices (Pain relief, muscle spasms, joint contractures, etc.)Matched to Predicate Devices (Pain relief, muscle spasms, joint contractures, etc.)
Prescriptive UseYesYes
Maximum adjustable therapy time60 min (for electrotherapy), 30 min (for ultrasound)60 min (electrotherapy, general), 30 min (ultrasound)
Patient Leakage Current (Normal)< 1mA< 1mA
Patient Leakage Current (Single Fault)< 0.5mA< 0.5mA
Compliance with Voluntary StandardsIEC/EN 60601-1, -1-2, -2-5, -2-10; 21 CFR 898Yes, IEC/EN 60601-1, -1-2, -2-5, -2-10; 21 CFR 898 (for relevant modules)
Electrotherapy Specifics (Examples)
Number of Output ModesVaried across predicates (e.g., 10 for Vectra Genisys, 5 for Galva 5M)8 (Interferential, Premodulated, Monophasic, Medium Frequency, Asymmetrical Biphasic, Symmetrical Biphasic, High Volt, Microcurrent)
Regulated Current/VoltageBoth CC and CVBoth CC and CV
Monophasic Rectangular (Max Output Voltage)25V@500Ω, 100V@2kΩ, 200V@10kΩ (Galva 5M)24.7V@500Ω, 99.9V@2kΩ, 180V@10kΩ
Microcurrent (Max Output Current)1mA@500Ω, 1mA@2KΩ, 1mA@10kΩ (Vectra Genisys)0.98mA@500Ω, 0.99mA@2kΩ, 1.02mA@10kΩ
Symmetric Biphasic Rectangular (Pulse Width)20μs-1000μs (Vectra Genisys), 100μs-1500μs (Galva 5M)100μs-1000μs
High Voltage (Max Output Current)250mA@500Ω, 100mA@2kΩ, 20mA@10kΩ (Galva 5M)250mA@500Ω, 75mA@2kΩ, 15mA@10kΩ
Ultrasound Specifics
Frequencies1 and 3.3MHz (Vectra Genisys), 0.8 and 3 MHz (Sono 5)0.8 and 2.4 MHz
Intensity0-3.0 W/cm²0-3.0 W/cm²
Duty CycleExamples: 1:1, 1:2, 1:5 (Vectra Genisys); 1:2, 1:5 (Sono 5)1:1, 1:2, 1:3, 1:5, 1:10
BNR5.0:1 or less (Vectra Genisys), 6.0:1 or less (Sono 5)4.3:1 or less
ERAVaried across predicates and applicator sizesExamples: 5cm²: 2.30 cm² (0.8MHz), 2.38 cm² (2.4MHz); 1cm²: 1.08 cm² (0.8MHz), 0.54 cm² (2.4MHz) (all values ±20%)

Note: The "acceptance criteria" here are implied by the specifications of the predicate devices. The study demonstrating compliance is the "Non-clinical Tests Performed" which verified the device's technical characteristics against these standards.

2. Sample size used for the test set and the data provenance (e.g. country of origin of the data, retrospective or prospective)

This information is not provided in the 510(k) summary. For a 510(k) submission, the primary "test set" is often the comparison of technical specifications against predicate devices and adherence to recognized standards. It's likely that internal engineering and performance testing was conducted, but details on sample size, data provenance, and study design are not typically required or included in this summary document beyond stating that "Validation documentation, product testing and a comparison of the technical characteristics and features according to relevant standards were provided."

3. Number of experts used to establish the ground truth for the test set and the qualifications of those experts (e.g. radiologist with 10 years of experience)

This is not applicable/not provided. The document describes a medical device, not an AI or diagnostic tool that requires expert-established ground truth for its performance evaluation in the clinical sense. The ground truth for this type of device is its adherence to technical specifications and safety standards as verified by engineering tests and comparison to predicate devices, and its intended effect being recognized within standard medical practices.

4. Adjudication method (e.g. 2+1, 3+1, none) for the test set

This is not applicable/not provided. Adjudication methods are typically associated with resolving discrepancies in expert interpretations during the establishment of ground truth for diagnostic studies, which is not the nature of this 510(k) submission.

5. If a multi reader multi case (MRMC) comparative effectiveness study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

This is not applicable/not provided. MRMC studies are used for evaluating the impact of AI on human reader performance for diagnostic tasks, which is not relevant to a powered muscle stimulator/ultrasound diathermy device. The study described is a technical comparison for substantial equivalence.

6. If a standalone (i.e. algorithm only without human-in-the-loop performance) was done

This is not applicable/not provided. This device is not an algorithm, but a physical medical device. Its "standalone" performance is its technical operation according to specifications, which was implicitly demonstrated through the non-clinical tests and comparison to predicates.

7. The type of ground truth used (expert consensus, pathology, outcomes data, etc)

The "ground truth" for this 510(k) submission is the technical specifications and safety performance demonstrated by the predicate devices and the relevant voluntary standards (e.g., IEC/EN 60601 series, 21 CFR 898). The new device is considered substantially equivalent if it meets or has comparable technical characteristics within the established safety and effectiveness profile of these predicate devices and standards.

8. The sample size for the training set

This is not applicable/not provided. This device does not involve a "training set" in the context of machine learning or AI.

9. How the ground truth for the training set was established

This is not applicable / not provided for the same reason as point 8.

{0}------------------------------------------------

Image /page/0/Picture/0 description: The image contains the logo for "zimmer MedizinSysteme". The word "zimmer" is in a bold, sans-serif font, with the "i" having a square dot. Below "zimmer" is the word "MedizinSysteme" in a smaller, sans-serif font. The logo appears to be a scan or photocopy, as the text has a slightly rough or pixelated appearance.

(12/059 AGE | OF ID

Zimmer Medizinsysteme GmbH Junkersstraße 9 D-89231 Neu-Uim

Tel. 073179761-0

info@zimmer.de Fax 0731 / 9761-118

www.zimmer.de

AUG

5. 510(k) Summary

The following information is provided as required in 21CFR807.87 and the Guidance Document "Guidance Document for Powered Muscle Stimulators 510(k)s"

a.) General

510(k) Submitter:Zimmer MedizinSysteme GmbHJunkersstrasse 9D-89231 Neu-UlmGermany
Contact person:Mr. Armin PétraschkaProject ManagerPhone: +49-731-9761-140Fax: +49-731-9761-4475E-mail: a.petraschka@zimmer.de
Establishment Registration:8010720
Submission Date:January 13th, 2012
Device Names:
Device family name:Soleoline
Trade Names:Soleo StimSoleo SonoSoleo SonoStim
Common Names:Ultrasound and muscle stimulatorPowered muscle stimulatorTranscutaneous electrical nerve stimulator for pain reliefUltrasonic diathermy
Regulation Numbers and Classification Names:21 CFR 890.5850 - Stimulator, Muscle, Powered21 CFR 890.5300 - Ultrasonic diathermy21 CFR 890.5860 - Ultrasound and muscle stimulator21 CFR 882.5890 - Transcutaneous electrical nerve stimulator for pain relief
Classification:Class II
Product Codes:IPF, IMI, IMG, GZJ
Panel:89 - Physical Medicine84 - Neurology

{1}------------------------------------------------

K121059 PAGE 2 OF IO

b.) Predicate Devices

1-Device:Manufacturer:510(k) number:Vectra GenisysCHATTANOOGA GROUP (Encore Medical)4717 adams rd. P.O. Box 489Hixson, Tennessee 37343-0489K031077
2.Device:Manufacturer:Galva 5 MZimmer MedizinSysteme GmbH (former Zimmer Elektromedizin GmbH)
Junkersstrasse 989231 Neu-UlmGermany
510(k) number:K954411
3.
Device:Sono 5
Manufacturer:Zimmer MedizinSysteme GmbH
Junkersstrasse 9
89231 Neu-Ulm
510(k) number:GermanyK952536

c.) Device Description

The Soleoline has a clear contemporary color screen showing all parameters necessary for therapy as well as modem touch control. Individual program start configuration and clear, simple menu navigation make operation of the device easy and comfortable for users. 120 storage bins for individual program settings makes working with the Soleoline a lot easier. The compact design saves room in the practice and is highly suited for use in home visits. The combination of electrotherapy and ultrasound therapy in a single system enables the use of the established combination therapy. It is a prescription device administered to patients by a licensed healthcare provider in hospitals, post acute care facilities, nursing homes and outpatient clinics.

Soleoline is a device family consisting of Soleo Stim and Soleo SonoStim, Soleo Sono includes an ultrasound module, Soleo Stim includes a stimulation current therapy module and Soleo SonoStim includes a combination of a stimulation current module and an ultrasound module.

The stimulation current module is used for stimulation current therapy according to the standard medical practices. It offers multiple waveforms; Monophasic, High Voltage, Micro Current, Asymmetrical Biphasic, Interferential, Medium Frequency, Premodulated currents for nerve stimulation and muscle therapy for mono channel and dual channel operation. The regulated output of the current stimulation module may be chosen from Constant Current (CC) or Constant Voltage (CV).

The dual frequency ultrasound module (800kHz and 2.4MHz) offers two different size ultrasound heads, 1cm² and 5cm² and pulsed and continuous duty cycles.

At combination therapy (simultaneous procedure) the features for ultrasound can be used together with the different stimulation waveforms. All functions of the 0.8MHz and 2.4MHz ultrasound can be combined with the following waveforms:

Monophasic, High Voltage, Micro Current, Symmetrical Biphasic, Medium Frequency, Premodulated

The therapy menu helps the clinicians to assign the indications of each body region to the appropriate therapy program.

{2}------------------------------------------------

K121059
PAGE 3 OF 10

d.) Statement of indications for use

The indications for use of the proposed device are the same as those for the predicate devices Ultrasound therapy:

  • Relief of pain, muscle spasms and joint contractures 1.
    • Relief of pain, muscle spasms and joint contractures that may be associated with: "
      • · Adhesive capsulitis
      • Bursitis with slight calcification o
      • · Myositis
      • Soft tissue injuries o
      • Shortened tendons due to past injuries and scar tissues o
    1. Relief of pain, muscle spasms and joint contractures resulting from:
    • · Capsular tightness
    • · Capsular scarring

Electrotherapy:

    1. Relaxation of muscle spasm
    1. Prevention or retardation of disuse atrophy
    1. Increasing local blood circulation
    1. Muscle re-education
    1. Immediate post-surgical stimulation of calf muscles to prevent venous thrombosis
  • ର. Maintaining or increasing range of motion
    1. Symptomatic relief or management of chronic, intractable pain
    1. Post-traumatic acute pain
  • ு. Post-surgical acute pain

e.) Comparison of Technological Characteristics

General:

FeatureZimmer Soleoline(Soleo Sono,Soleo Stim,Soleo SonoStim)Chattanooga VectraGenisys w/o EMGZimmer Galva 5Zimmer Sono 5
Number of channels22/42-
Number of connections221-
Touch screen interface+---
Color LCD screen++--
Intended useUltrasound diathermy,Powered musclestimulator,Ultrasound andmuscle stimulatorUltrasound and musclestimulatorPowered musclestimulator,Ultrasound diathermy
IndicationselectrotherapyRelaxation ofmuscle spasmPrevention orretardation ofdisuse atrophyIncreasing localblood circulationMuscle re-educationImmediate post-surgicalstimulation of calfRelaxation ofmuscle spasmPrevention orretardation ofdisuse atrophyIncreasing localblood circulationMuscle re-educationImmediate post-surgicalstimulation of calfRelaxation of musclespasmPrevention orretardation of disuseatrophyIncreasing localblood circulationMuscle re-educationImmediate post-surgical stimulationof calf muscles toprevent thrombosis-

{3}------------------------------------------------

K121059

PASE 4 OF D

muscles tomuscles toMaintaining or
preventpreventincreasing range of
thrombosisthrombosismotion
Maintaining orMaintaining or
increasing rangeincreasing range
of motionof motion
SymptomaticSymptomatic
relief orrelief or
management ofmanagement of
chronic,chronic,
intractable painintractable pain
Post-traumaticPost-traumatic
acute painacute pain
Post-surgicalPost-surgical
acute painacute pain
Indications ultrasoundRelief of pain,Relief of pain,Relief of pain
therapymuscle spasmsmuscle spasmsMuscle spasm
and jointand jointJoint contractures
contracturescontractures
Relief of pain,Relief of pain,
muscle spasmsmuscle spasms
and jointand joint
contractures thatcontractures that
may bemay be
associated with:associated with:
• Adhesive• Adhesive
capsulitiscapsulitis
• Bursitis with• Bursitis with
slightslight
calcificationcalcification
• Myositis• Myositis
• Soft tissue• Soft tissue
injuriesinjuries
• Shortened• Shortened
tendons due totendons due to
past injuriespast injuries
and scarand scar
tissuestissues
Relief of pain,Relief of pain,
muscle spasmsmuscle spasms
and jointand joint •
contracturescontractures
resulting from:resulting from:
• Capsular• Capsular
tightnesstightness
• Capsular• Capsular
scarringscarring
Prescriptive use++++
Maximum adjustable therapyMaximum adjustable therapy time [min]6060606060603030
Modifiable Waveform Parameters+++-
Power source(s)Universal power supply:100 - 240VAC, 50/60HzOnboard switchable power supply:120/240VAC, 50/60Hz120 VAC, 60Hz120 VAC, 60Hz
Method of Line Current IsolationFuse - Two 2,0A Time LagFuse - Two 5.6A Time LagDecoupling by mains transformer, Fuses, Electrical overcurrent limiterN/A
Patient Leakage Current:Normal condition< 1mA69μΑ< 1mA< 1mA
Patient Leakage Current:Single fault condition< 0.5mA31μΑ< 0.5mA< 0.5mA

Author: A. Petraschka
510 (k) Premarket Notification Soleoline

.

·

·

{4}------------------------------------------------

K121059

PAGE 5 OF ID

Number of Output Modes8: Interferential,Premodulated,Monophasic, MediumFrequency,AsymmetricalBiphasic, SymmetricalBiphasic, High Volt,Microcurrent10: Interferential,Premodulated, VMS,VMS Burst, Russian,AsymmetricalBiphasic, SymmetricalBiphasic, High Volt,Microcurrent, DirectCurrent5: Diadynamic current,Medium Frequency,Monophasic, Biphasicsymmetric, High voltage
Number of Output Channels22 & 4 channel units1-
Synchronous or AlternatingBothBothSynchronous-
Method of Channel IsolationLAN spacingscompliant with IEC60601-1 isolationrequirementsLAN spacingscompliant with IEC60601-1 isolationrequirements, andprotective softwareisolation--
Regulated Current orRegulated Voltage?Yes, both CC and CVYes, both CC and CVYes, both CC and CV-
Software/Firmware/Microprocessor Control?++++
Automatic Overload Trip?++++
Automatic No-load Trip?----
Automatic Shut-Off?++++
Patient Override Control?+++N/A
Indicator Display:On/Off Status++++
Low BatteryVoltage/Current LevelN/AN/AN/AN/A
Compliance with VoluntaryStandards?Yes, IEC/EN 60601-1,IEC/EN60601-1-2,IEC/EN 60601-2-5,IEC/EN 60601-2-10,Yes, IEC/EN 60601-1,IEC/EN60601-1-2,IEC/EN 60601-2-5,IEC/EN 60601-2-10,Yes, IEC/EN 60601-1,IEC/EN60601-1-2,IEC/EN 60601-2-10,Yes, IEC/EN 60601-1,IEC/EN60601-1-2,IEC/EN 60601-2-5
Compliance with 21 CFR898++++
Dimensions (w x d x h)[cm]32.2 x 23.4 x 1328.9 x 32.4 x 22.245 x 32.5 x 143.25 x 4.5 x 1.4
Weight[kg]2.13.25.76.8
Housing Materials andConstructionMolded PC-ABSplastic material withscrew assemblyconstructionABS/PC injection-molded top andbottom shells,Thermo-PlasticElastomer (TPE)partial overmolding ontop, Acryl lens, Topand bottom aresecured together withmachine screws.Bottom and front:Polystyrene;Cover: steel sheet;Front panel: glassBottom and front:Polystyrene;Cover: steel sheet;Front panel: glass
Surge ModeRamp up:0.5 - 60sOn Time:0 - 60sRamp down:0.2 - 5sN/ARamp up:0.5 - 60sOn Time:0 - 60sRamp down:0.5s-
SpecificationsNew DeviceVectra GenisysGalva 5M
WaveformMonophasic-Biphasic symmetric
ShapeRectangular-Rectangular
Maximum Output Voltage(+/- 20 %)24.7V@500Ω99.9V@2kΩ180V@10kΩ-25V@500Ω100V@2kΩ200V@10kΩ
Maximum Output Current(+/- 20 %)50mA@500Ω50mA@2kΩ12mA@10kΩ-50mA@500Ω50mA@2kΩ20mA@10kΩ
Pulse Width200μs – 1500μs-200μs – 1500μs
Frequency [Hz]0-1667-0-1667
Beat Frequency [Hz]N/A-N/A
Symmetrical PhasesNo-No
Phase Duration200μs – 1500μs-200μs – 1500μs
Net Charge75μC-75μC
Maximum Phase Charge75μC-75μC
Maximum Current Density [mA/cm²]3.9@500Ω-3.9@500Ω
Maximum Power Density [W/cm²]0.097@500Ω-0.097@500Ω
Burst ModeN/A-N/A
a. Pulses per burst [PPB]N/A-N/A
b. Bursts per second [BPS]N/A-N/A
c. Burst duration [BD]N/A-N/A
d. Duty CycleN/A-N/A
ON TimeSee surge mode point 28.-See surge mode point 28.
OFF TimeSee surge mode point 28.-See surge mode point 28.
Additional FeaturesPolarity reversal: Selectable. positive, negative or alternating; switches after each minute-Polarity reversal: Selectable. positive, negative or alternating; switches after each minute

.

.

. .

{5}------------------------------------------------

Output specifications:

.

Monophasic rectangular:

Microcurrent:

SpecificationsNew DeviceVectra GenisysGalva 5M
WaveformMicrocurrent, monophasicMicrocurrent, monophasic-
ShapeRectangularRectangular-
Maximum Output Voltage(+/- 20 %)0.49V@500Ω1.98V@2kΩ10.20V@10kΩ0.51V@500Ω2V@2KΩ10V@10kΩ-
Maximum Output Current(+/- 20%)0.98mA@500Ω0.99mA@2kΩ1.02mA@10kΩ1mA@500Ω1mA@2KΩ1mA@10kΩ-
Pulse Width1ms-10000ms1ms-10000ms-
Frequency [Hz]0.1-10000.1-1000-
Beat Frequency [Hz]N/AN/A-
Symmetrical PhasesNoNo-
Phase Duration0.5ms-5000ms.0.5ms-5000ms-
Net ChargeN/A (monophasic)N/A (monophasic)-
Maximum Phase Charge5000μC5000μC-
Maximum Current Density[mA/cm²]0.078@500Ω0.026@500Ω-
Maximum Power Density[W/cm²]0.4*10-4@500Ω0.1*10-4@500Ω-
Burst ModeN/AN/A-
a. Pulses per burst [PPB]N/AN/A-
b. Bursts per second [BPS]N/AN/A-
c. Burst duration [BD]N/AN/A-
d. Duty CycleN/AN/A-
ON TimeSee surge mode point 28.N/A-

{6}------------------------------------------------

The first of the count of the count of the count of the county of the county ofOFF TimeStatus of the American of Children of ChildrenA Status of Children Comments of Children Comments of ChildrenonSee surge modepoint 28.100 - 400 - 400 - 400 - 400 - 400 - 400 - 4000 - 4000 - 4000 - 4000 - 1000 - 1000 - 1000 - 1000 - 1000 - 1000 - 1000 - 1000 - 1000 - 1000 - 1000 - 1000 - 1000 - 1000 - 1000 -And American Company of Comments of------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Additional FeaturesAcres of Acres of Acres of AcresN/AA . Annual of all and and on AlleActive And CharlesNIAAnd Annon Charles Children ChildrenA 400-600-August

·

.

Symmetric biphasic rectanqular;
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
SpecificationsNew DeviceVectra GenisysGalva 5M
WaveformBiphasic symmetricBiphasic symmetricBiphasic symmetric
ShapeRectangularRectangularRectangular
Maximum Output Voltage40V@500Ω40V@500Ω25V@500Ω
(+/-20 %)146V@2kΩ158V@2kΩ100V@2kΩ
150V@10kΩ200V@10kΩ200V@10kΩ
Maximum Output Current80mA@500Ω80mA@500Ω50mA@500Ω
(+/-20 %)73mA@2kΩ79mA@2kΩ50mA@2kΩ
15mA@10kΩ20mA@10kΩ20mA@10kΩ
Pulse Width100μs -1000μs20μs-1000μs100μs-1500μs
Frequency [Hz]0-16671-2500-1667
Beat Frequency [Hz]N/AN/AN/A
Symmetrical PhasesYesYesYes
Phase Duration50μs-500μs10μs-500μs50μs-750μs
Net Charge0 (symmetric)0 (symmetric)0 (symmetric)
Maximum Phase Charge80μC80μC75μC
Maximum Current Density6.25@500Ω2.08@500Ω3.9@500Ω
[mA/cm²]
Maximum Power Density0.25@500Ω0.083@500Ω0.097@500Ω
[W/cm²]
Burst ModeN/A
a. Pulses per burst (PPB)5-1007N/A
b. Bursts per second (BPS)1-2001 - 10N/A
c. Burst duration (BD)0.7-0.028s0.7 - 0.028sN/A
d. Duty Cycle1 - 0.00420.7 - 0.28N/A
ON TimeSee surge mode point 28.See additional featuresSee surge mode point 28.
OFF TimeSee surge mode point 28.See additional featuresSee surge mode point 28.
Additional FeaturesSee definition surge modeCycle times of 4/4, 4/8, 7/7, 5/5,4/12, 10/10, 10/20, 10/30, 10/50,continuous (On/Off)See definition surge mode

Asymmetric biphasic rectanqular:

・ー

SpecificationsNew DeviceVectra GenisysGalva 5M
WaveformBiphasic symmetricBiphasic symmetric-
ShapeRectangularRectangular-
Maximum Output Voltage(+/- 20 %)48V@500Ω104V@2kΩ153V@10kΩ55V@500Ω197V@2kΩ200V@10kΩ-
Maximum Output Current(+/- 20 %)100mA@500Ω52mA@2kΩ15mA@10kΩ110mA@500Ω99mA@2kΩ20mA@10kΩ-
Pulse Width20µs-1000µs20µs-1000µs-
Frequency [Hz]1-3311-250-
Beat Frequency [Hz]N/AN/A-
Symmetrical PhasesNoNo-
Phase Duration20µs-1000µs positive2000µs negative20µs-1000µs positive80µs-4000µs negative-
Net Charge0 (symmetric)0 (symmetric)-
Maximum Phase Charge100µC110µC-
Maximum Current Density[mA/cm²]6.25@500Ω2.86@500Ω-
Maximum Power Density[W/cm²]0.25@500Ω0.157@500Ω-
Burst Mode
a. Pulses per burst [PPB]77-
b. Bursts per second [BPS]1 - 101 - 10-
c. Burst duration [BD]0.7 - 0.028s0.7 - 0.028s-
d. Duty Cycle0.7 - 0.00280.7 - 0.28-
ON TimeSee surge mode point 28See additional features-

.

{7}------------------------------------------------

K121059 PAGE 8 OF ID

OFF TimeSee surge mode point 28.See additional features-
Additional FeaturesSee definition surge modeCycle times of 4/4, 4/8, 7/7, 5/5, 4/12, 10/10, 10/20, 10/30, 10/50, continuous (On/Off);-
High Voltage:
SpecificationsNew DeviceVectra GenisysGalva 5M
WaveformHigh Voltage, monophasic symmetric-High Voltage, monophasic symmetric
ShapeRectangular-Rectangular
Maximum Output Voltage (+/- 20 %)122V@500Ω180V@2kΩ180V@10kΩ-125V@500Ω200V@2kΩ200V@10kΩ
Maximum Output Current (+/- 20 %)250mA@500Ω75mA@2kΩ15mA@10kΩ-250mA@500Ω100mA@2kΩ20mA@10kΩ
Pulse Width10μs-100μs-10μs-100μs
Frequency [Hz]0-1961-0-1961
Beat Frequency [Hz]N/A-N/A
Symmetrical PhasesNo-No
Phase Duration10μs-100μs-10μs-100μs
Net Charge25μC-25μC
Maximum Phase Charge25μC-25μC.
Maximum Current Density [mA/cm²]19.5@500Ω-19.5@500Ω
Maximum Power Density [W/cm²]2.44@500Ω-2.44@500Ω
Burst ModeN/A-N/A
a. Pulses per burst [PPB]N/A-N/A
b. Bursts per second [BPS]N/A-N/A
c. Burst duration [BD]N/A-N/A
d. Duty CycleN/A-N/A
ON TimeSee surge mode point 28.-See surge mode point 28.
OFF TimeSee surge mode point 28.-See surge mode point 28.
Additional FeaturesPolarity reversal: Selectable. positive, negative or alternating-Polarity reversal: Selectable. positive, negative or alternating
SpecificationsNew DeviceVectra GenisysGalva 5M
WaveformMedium FrequencyMedium FrequencyMedium Frequency
ShapeSinusoidal, unmodulatedSinusoidal, unmodulatedSinusoidal, unmodulated
Maximum Output Voltage(+/- 20 %)50V@500Ω157V@2kΩ153V@10kΩ52V@500Ω188V@2kΩ200V@10kΩ60V@500Ω206V@2kΩ200V@10kΩ
Maximum Output Current(+/- 20 %)99mA@500Ω77mA@2kΩ15 mA@10kΩ104mA@500Ω94mA@2kΩ20mA@10kΩ120mA@500Ω100mA@2kΩ20mA@10kΩ
Pulse WidthN/AN/AN/A
Frequency [Hz]2000-80002000-100005000
Beat Frequency [Hz]N/AN/AN/A
Symmetrical PhasesYesYesYes
Phase DurationN/AN/AN/A
Net Charge0 (symmetric)0 (symmetric)0 (symmetric)
Maximum Phase Charge15.9μC16.6μC7.64μC
Maximum Current Density[mA/cm²]4.38@500Ω2.6@500Ω9.4@500Ω
Maximum Power Density[W/cm²]0.123@500Ω0.129@500Ω0.562@500Ω
Burst ModeN/AN/AN/A
a. Pulses per burst [PPB]N/AN/A17.5-835
b. Bursts per second [BPS]N/AN/A0.1-250Hz
c. Burst duration [BD]N/AN/A3.5ms-167ms
d. Duty CycleN/AN/AN/A

{8}------------------------------------------------

Off E9OF10

ON TimeSee surge mode point 28.See additional featuresSee surge mode point 28.
OFF TimeSee surge mode point 28.See additional featuresSee surge mode point 28.
Additional FeaturesSee definition surge modeCycle Times of 5/5, 4/12, 10/10,10/20, 10/30, 10/50, Continuous(On/Off)See definition surge mode
Premodulated:
SpecificationsNew DeviceVectra GenisysGalva 5M
WaveformMedium FrequencyMedium Frequency-
ShapeSinusoidal, modulatedSinusoidal, modulated-
Maximum Output Voltage(+/- 20 %)50V@500Ω162V@2kΩ166V@10kΩ52V@500Ω188V@2kΩ200V@10kΩ-
Maximum Output Current(+/- 20 %)100mA@500Ω81mA@2kΩ17mA@10kΩ104mA@500Ω94mA@2kΩ20mA@10kΩ-
Pulse Width12.5μs-500μs10μs-500μs-
Frequency [Hz]2000-80002000-10000-
Beat Frequency [Hz]1-2001-200-
Symmetrical PhasesYesYes-
Phase Duration6.25μs-250μs5μs-250μs-
Net Charge0 (symmetric)0 (symmetric)-
Maximum Phase Charge15.9μC16.6μC-
Maximum Current Density [mA/cm²]6.25@500Ω2.6@500Ω-
Maximum Power Density [W/cm²]0.25@500Ω0.129@500Ω-
Burst ModeN/AN/A-
a. Pulses per burst [PPB]N/AN/A-
b. Bursts per second [BPS]N/AN/A-
c. Burst duration [BD]N/AN/A-
d. Duty CycleN/AN/A-
ON TimeSee surge mode point 28.See additional features.-
OFF TimeSee surge mode point 28.See additional features-
Additional FeaturesSee surge mode point 28.Cycle Times of 5/5, 4/12, 10/10,10/20, 10/30, 10/50, Continuous(On/Off)-

Interferential:

SpecificationsNew DeviceVectra GenisysGalva 5M
WaveformInterferentialInterferential-
ShapeSinusoidal, channel modulationSinusoidal, channel modulation-
Maximum Output Voltage(+/- 20 %)52V@500Ω164V@2kΩ103V@10kΩ52V@500Ω172V@2kΩ200V@10kΩ-
Maximum Output Current(+/- 20 %)103mA@500Ω82mA@2kΩ10mA@10kΩ100mA@500Ω86mA@2kΩ19mA@10kΩ-
Pulse WidthN/AN/A-
Frequency [Hz]2000-80002000-10000-
Beat Frequency [Hz]1-2001-200-
Symmetrical PhasesYesYes-
Phase DurationN/AN/A-
Net Charge0 (symmetric)0 (symmetric)-
Maximum Phase Charge16.4μC15.9μC-
Maximum Current Density [mA/cm²]6.25@500Ω2.6@500Ω-
Maximum Power Density [W/cm²]0.25@500Ω0.129@500Ω-
Burst ModeN/AN/A-
a. Pulses per burst [PPB]N/AN/A-
b. Bursts per second [BPS]N/AN/A-
c. Burst duration (BD)N/AN/A-

{9}------------------------------------------------

K121059
PAGE 10 OF 10

A1737ﺎ ﻓﺎ ﻛﺴﺎﺭ ﺍﻟﻤﺴﺎﺣﺔ ﺍﻟﻤﺴﺎﺑﻘﺔ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤﺘﺤﺪﺓ ﺍﻟﻤwww.rademall.com/should/ship/divide/space.AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACompany of Children Company of Children Company ofN/P------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Company of Children------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-N/r.----------
i imeAAAAAA----------NA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Authorized which theBucker Book Book BBARRANGEWF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
AFF Tthe---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N/F
1000 2111N/A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LANDA

Ultrasound Specification

ParameterNew DeviceVectra GenisysSono 5
Frequencies0.8 and 2.4 MHz1 and 3.3MHz0.8 and 3 MHz
Intensity0-3.0 W/cm²0-3.0W/cm²0-3.0W/cm²
Wave formPulsed, continuousPulsed, continuousPulsed, continuous
Pulse Rate20Hz, 50Hz, 100Hz100Hz20Hz, 50Hz
Duty Cycle1:1, 1:2, 1:3, 1:5, 1:101:1, 1:2, 1:51:2, 1:5
Treatment Time0-30 Minutes0-30 Minutes0-30 Minutes
Applicator Sizes1cm², 5cm²1cm², 2cm², 5cm², 10cm²1.5 cm², 5 cm²
Maximum output5 cm²: 0-6.9W (800kHz),0-7.1W (2.4MHz)1 cm²: 0-1W (800kHz),0-0.6W (2.4MHz)10 cm²: 0-20 W (1MHz),0-10 W (3.3 MHz)5 cm²: 0-10 W,(1 and 3.3 MHz)2 cm²: 0-4 W,(1 and 3.3 MHz)1 cm²: 0-2 W(3.3 MHz only)5 cm²: 0-10W (800kHz),1.5 cm²: 0-1W (2.4MHz)
BNR4.3:1 or less5.0:1 or less6.0:1 or less
ERA.5 cm²: 2,30 cm² (0,8MHz)2,38 cm² (2,4MHz)1 cm²: 1,08 cm² (0,8MHz)0,54 cm² (2,4MHz)all values ±20%10 cm²: 8.5 cm², ±1.55 cm²: 4.0 cm², ±1.02 cm²: 1.8 cm², +0.2/-0.41 cm²: 0.8 cm², +0.2/-0.45 cm²: 3.3 cm²,1.5 cm²: 1.0 cm²,all values ±20%
Applicator Temporal Peak/ Average Ratio1:1, 2:1, 3:1, 5:1, 10:12:1, 5:1, 9:12:1, 5:1

f.) Summary Comparison with predicate devices

The Soleo Sono, Soleo Stim and Soleo SonoStim share intended use and the same or similar basic characteristics and features as the predicate devices. In addition, any differences in their technological characteristics are explained to demonstrate in this submission that these differences do not raise any new questions of safety and effectiveness.

g.) Non-clinical Tests Performed

Validation documentation, product testing and a comparison of the technical characteristics and features according to relevant standards were provided to demonstrate that Soleo Stim and Soleo SonoStim are safe and effective in its intended use.

h.) Conclusion Substantial Equivalence

Drawn from the comparison between the predicate devices it demonstrates that the Soleoline devices are as safe and effective as the predicate devices and therefore are substantially equivalent to the compared devices on the basis of similarities in operating principles, intended use and functional performance.

{10}------------------------------------------------

DEPARTMENT OF HEALTH & HUMAN SERVICES

Image /page/10/Picture/1 description: The image shows the logo for the Department of Health & Human Services (HHS). The logo features a stylized depiction of an eagle or bird-like figure with three curved lines forming its body and wings. The text "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" is arranged in a circular pattern around the bird symbol. The logo is in black and white.

Food and Drug Administration 10903 New Hampshire Avenue Document Control Room -WO66-G609 Silver Spring, MD 20993-0002

Zimmer MedizinSysteme GmbH % TÜV SÜD America, Incorporated Mr. Alexander Schapovalov 1775 Old Highway 8 New Brighton, Minnesota 55112-1891

AUG 7 2012

Re: K121059

Trade/Device Name: Soleo Sono, Soleo Stim, and Soleo SonoStim Regulation Number: 21 CFR 890.5860 Regulation Name: Ultrasound and muscle stimulator Regulatory Class: II Product Code: IMG, IPF, IMI, GZJ, LIH Dated: July 18, 2012 Received: July 23, 2012

Dear Mr. Schapovalov:

We have reviewed your Section 510(k) premarket notification of intent to market the device we have as nowed your would the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate for ass barrain to May 28, 1976, the enactment date of the Medical Device Amendments, or to conninered pror to 114) 2011-12-11 in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The I ou may, therefore, mains of the Act include requirements for annual registration, listing of general controls proficturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you, however, that device labeling must be truthful and not misleading.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it If your device is blassified (ooo arols. Existing major regulations affecting your device can be may or salled of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act that I Dri has made a averalations administered by other Federal agencies. You must of any I odetar statures and states and one of limited to: registration and listing (21 Comply with an the Pict of CFR Part 801); medical device reporting (reporting of medical CI IT rat 007), hooimly (21 CFR 803); good manufacturing practice requirements as set

{11}------------------------------------------------

Page 2 - Mr. Alexander Schapovalov

forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please go to http://www.fda.gov/AboutFDA/CentersOffices/CDRH/CDRHOffices/ucm115809.htm for the Center for Devices and Radiological Health's (CDRH's) Office of Compliance. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to

http://www.fda.gov/MedicalDevices/Safety/ReportaProblem/default.htm for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance.

You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 796-7100 or at its Internet address http://www.fda.gov/MedicalDevices/Resourcesfor You/Industry/default.htm.

Sincerely yours,
Mark N. Milliken

Mark N. Melkerson Director Division of Surgical, Orthopedic and Restorative Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

{12}------------------------------------------------

Image /page/12/Picture/0 description: The image shows the logo for Zimmer MedizinSysteme. The logo is in black and white and features the word "zimmer" in a stylized font. Below the word "zimmer" is the phrase "MedizinSysteme" in a smaller, sans-serif font.

K121059
PAGE 1 OF 2

  • MedizinSystem.

Zimmer Medizinsysteme GmbH Junkersstraße 9 D-89231 Neu-Ulm

Tel. 0731 / 9761-0

Fax 073179761-118

info@zimmer.de www.zimmer.de

4. Indications for Use Statement

Indications for Use Soleo Sono:

Ultrasound therapy:

Relief of pain, muscle spasms and joint contractures
Relief of pain, muscle spasms and joint contractures that may be associated with:
• Adhesive capsulitis
• Bursitis with slight calcification
• Myositis
• Soft tissue injuries
• Shortened tendons due to past injuries and scar tissues
Relief of pain, muscle spasms and joint contractures resulting from:
• Capsular tightness.
• Capsular scarring

Indications for Use Soleo Stim:

Electrotherapy:

For Medium Frequency, Monophasic Currents, Biphasic Symmetric Currents and High Voltage

Relaxation of muscle spasm

Prevention or retardation of disuse atrophy

Increasing local blood circulation

Muscle re-education

Immediate post-surgical stimulation of calf muscles to prevent venous thrombosis

Maintaining or increasing range of motion

For IFC, Premodulated, Microcurrent, Asymmetric Biphasic Currents and Symmetric Biphasic Currents

Symptomatic relief or management of chronic, intractable pain Post-traumatic acute pain Post-surgical acute pain

Vanderly C. Clay

(Division Sign-Off) Division of Surgical, Orthopedic, and Restorative Devices

510(k) Number K121059

{13}------------------------------------------------

K121059
PAGE 2 OF 2

Indications for Use Soleo SonoStim:

Ultrasound therapy:

Relief of pain, muscle spasms and joint contractures
Relief of pain, muscle spasms and joint contractures that may be associated with:
Adhesive capsulitis
Bursitis with slight calcification
Myositis
Soft tissue injuries
Shortened tendons due to past injuries and scar fissues
Relief of pain, muscle spasms and joint contractures resulting from:
Capsular tightness
Capsular scarring

Electrotherapy:

For Medium Frequency, Monophasic Currents, Biphasic Symmetric Currents and High Voltage

(

Relaxation of muscle spasm

Prevention or retardation of disuse atrophy Increasing local blood circulation

Muscle re-education

Immediate post-surgical stimulation of calf muscles to prevent venous thrombosis

Maintaining or increasing range of motion

For IFC, Premodulated, Microcurrent, Asymmetric Biphasic Currents and Symmetric Biphasic Currents

Symptomatic relief or management of chronic, intractable pain

Post-traumatic acute pain

Post-surgical acute pain

Prescription Use _ x (21 CFR 801 Subpart D)

AND/OR Over-the-counter Use (21 CFR 807 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE OF NEEDED)

Concurrence of CDRH, Office of Device Evaluation(ODE)
(Division Sign-Off)
Division of Surgical, Orthopedic,
and Restorative Devices

510(k) Number: K121059

§ 890.5860 Ultrasound and muscle stimulator.

(a)
Ultrasound and muscle stimulator for use in applying therapeutic deep heat for selected medical conditions —(1)Identification. An ultrasound and muscle stimulator for use in applying therapeutic deep heat for selected medical conditions is a device that applies to specific areas of the body ultrasonic energy at a frequency beyond 20 kilohertz and that is intended to generate deep heat within body tissues for the treatment of selected medical conditions such as relief of pain, muscle spasms, and joint contractures, but not for the treatment of malignancies. The device also passes electrical currents through the body area to stimulate or relax muscles.(2)
Classification. Class II (performance standards).(b)
Ultrasound and muscle stimulator for all other uses —(1)Identification. An ultrasound and muscle stimulator for all other uses except for the treatment of malignancies is a device that applies to the body ultrasonic energy at a frequency beyond 20 kilohertz and applies to the body electrical currents and that is intended for the treatment of medical conditions by means other than the generation of deep heat within body tissues and the stimulation or relaxation of muscles as described in paragraph (a) of this section.(2)
Classification. Class III (premarket approval).(c)
Date PMA or notice of completion of PDP is required. A PMA or notice of completion of a PDP for a device described in paragraph (b) of this section is required to be filed with the Food and Drug Administration on or before July 13, 1999 for any ultrasound and muscle stimulator described in paragraph (b) of this section that was in commercial distribution before May 28, 1976, or that has, on or before July 13, 1999, been found to be substantially equivalent to an ultrasound and muscle stimulator described in paragraph (b) of this section that was in commercial distribution before May 28, 1976. Any other ultrasound and muscle stimulator described in paragraph (b) of this section shall have an approved PMA or declared completed PDP in effect before being placed in commercial distribution.