K Number
K081777
Device Name
VENTRIO HERNIA PATCH
Manufacturer
Date Cleared
2008-09-29

(98 days)

Product Code
Regulation Number
878.3300
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
The Ventrio Hernia Patch is indicated for use in the reconstruction of soft tissue deficiencies, such as for the repair of hernias.
Device Description
The proposed Ventrio Hernia Patch is a self-expanding, sterile prosthesis, containing two primary layers of mesh stitched with polytetrafluoroethylene (PTFE) monofilament to an expanded polytetrafluoroethylene (ePTFE) sheet. The mesh component is non-absorbable, however, the device contains a fully absorbable recoil ring using AbsorbaFlex Memory Technology, an absorbable polydioxanone (PDO) monofilament. The AbsorbaFlex Memory Technology's PDO monofilament ring provides memory and stability to the device, facilitating ease of initial insertion, proper placement, and fixation of the device. The mesh component of the device is constructed of knitted polypropylene monofilament approximately 0.006" in diameter. The AbsorbaFlex PDO monofilament ring is 0.038" in diameter. It has two donut-shaped layers of knitted polypropylene monofilament mesh 0.006" in diameter on each side of the ring. These layers of mesh are stitched together around the ring using PTFE monofilament. The extra large oval sized patches contain inner and outer PDO monofilament rings. A single layer of expanded ePTFE is attached to the bottom primary layer of polypropylene mesh (posterior mesh). The attachment is accomplished with an interlocking stitch using PTFE monofilament. The peripheral edge of the polypropylene mesh will be heat sealed to the ePTFE layer.
More Information

Not Found

No
The device description focuses on the physical materials and construction of a hernia patch, with no mention of software, algorithms, or data processing that would indicate AI/ML. The performance studies are based on bench testing and resorption studies, not algorithmic performance.

Yes
The device is a hernia patch, used for the reconstruction of soft tissue deficiencies, which is a therapeutic intervention.

No

This device is a surgical implant designed for the reconstruction of soft tissue deficiencies and hernia repair. It is a therapy, not a tool for diagnosis.

No

The device description clearly details a physical hernia patch made of various materials (mesh, PTFE, ePTFE, PDO). There is no mention of software as a component or the primary function of the device.

No, this device is not an IVD (In Vitro Diagnostic).

Here's why:

  • IVD Definition: In Vitro Diagnostics are medical devices used to perform tests on samples taken from the human body (like blood, urine, or tissue) to provide information about a person's health. These tests are performed outside the body.
  • Device Description and Intended Use: The Ventrio Hernia Patch is a physical implant designed for the surgical repair of soft tissue deficiencies and hernias. It is a prosthesis that is placed inside the body.
  • Lack of Diagnostic Function: The description focuses on the physical properties and function of the patch as a structural support. There is no mention of it being used to analyze samples or provide diagnostic information.

The device is a surgical implant, not a diagnostic tool.

N/A

Intended Use / Indications for Use

The Ventrio Hernia Patch is indicated for use in the reconstruction of soft tissue deficiencies, such as for the repair of hernias.

Product codes

FTL

Device Description

The proposed Ventrio Hernia Patch is a self-expanding, sterile prosthesis, containing two primary layers of mesh stitched with polytetrafluoroethylene (PTFE) monofilament to an expanded polytetrafluoroethylene (ePTFE) sheet. The mesh component is non-absorbable, however, the device contains a fully absorbable recoil ring using AbsorbaFlex Memory Technology, an absorbable polydioxanone (PDO) monofilament. The AbsorbaFlex Memory Technology's PDO monofilament ring provides memory and stability to the device, facilitating ease of initial insertion, proper placement, and fixation of the device.

The mesh component of the device is constructed of knitted polypropylene monofilament approximately 0.006" in diameter. The AbsorbaFlex PDO monofilament ring is 0.038" in diameter. It has two donut-shaped layers of knitted polypropylene monofilament mesh 0.006" in diameter on each side of the ring. These layers of mesh are stitched together around the ring using PTFE monofilament. The extra large oval sized patches contain inner and outer PDO monofilament rings. A single layer of expanded ePTFE is attached to the bottom primary layer of polypropylene mesh (posterior mesh). The attachment is accomplished with an interlocking stitch using PTFE monofilament. The peripheral edge of the polypropylene mesh will be heat sealed to the ePTFE layer.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

soft tissue deficiencies, hernias

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Not Found

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies (study type, sample size, AUC, MRMC, standalone performance, key results)

Laboratory bench testing and in vitro and in vivo resorption studies were performed to verify that the proposed product's performance characteristics are similar to that of the predicate device. Laboratory bench testing was performed to compare the proposed Ventrio Hernia Patch to the currently marketed Bard Composix Kugel Hernia Patch*. In addition, in-vitro and in-vivo resorption studies were also performed on the proposed device to characterize the mechanical strength and resorption of the PDO monofilament. The results show that the proposed device is as safe and effective for its intended use as the currently marketed predicate device.

Key Metrics (Sensitivity, Specificity, PPV, NPV, etc.)

Not Found

Predicate Device(s)

K061314, K061533, K081069, K022782

Reference Device(s)

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information

Not Found

§ 878.3300 Surgical mesh.

(a)
Identification. Surgical mesh is a metallic or polymeric screen intended to be implanted to reinforce soft tissue or bone where weakness exists. Examples of surgical mesh are metallic and polymeric mesh for hernia repair, and acetabular and cement restrictor mesh used during orthopedic surgery.(b)
Classification. Class II.

0

K081777 page i/2

SEP 2 9 2008

510(K) SUMMARY OF SAFETY AND EFFECTIVENESS SECTION 7.0

Submitter Information A.

Submitter's Name: Address:

  • Telephone: Fax: Contact Person: Date of Preparation:
    Davol Inc. Subsidiary of C. R. Bard, Inc. 100 Crossings Boulevard Warwick, RI 02886 (401) 825-8588 (401) 825-8765 Stephanie Baker June 20, 2008

B. Device Name

Trade Name: Common/Usual Name: Classification Name:

Ventrio Hernia Patch Surgical Mesh Mesh, Surgical, Polymeric

C. Predicate Device Name

Trade name:

Bard Composix Kugel Hernia Patch* (Davol Inc.) (K061314); Ethicon PROCEED Ventral Patch (K061533); W.L. Gore INFINIT Mesh (K081069) and DualMesh® EMERGE PLUS Biomaterial (K022782).

D. Device Description

The proposed Ventrio Hernia Patch is a self-expanding, sterile prosthesis, containing two primary layers of mesh stitched with polytetrafluoroethylene (PTFE) monofilament to an expanded polytetrafluoroethylene (ePTFE) sheet. The mesh component is non-absorbable, however, the device contains a fully absorbable recoil ring using AbsorbaFlex Memory Technology, an absorbable polydioxanone (PDO) monofilament. The AbsorbaFlex Memory Technology's PDO monofilament ring provides memory and stability to the device, facilitating ease of initial insertion, proper placement, and fixation of the device.

PREMARKET NOTIFICATION FOR THE VENTRIO HERNIA PATCH

-CONFIDENTIAL-

  • The Ventrio Hernia Patch is substantially equivalent to the modified Bard Composix Kugel Hernia Patch containing the re-designed recoil ring covered under 510(k) K061314, cleared on June 2, 2006

1

Kosi777 page 2/2

The mesh component of the device is constructed of knitted polypropylene monofilament approximately 0.006" in diameter. The AbsorbaFlex PDO monofilament ring is 0.038" in diameter. It has two donut-shaped layers of knitted polypropylene monofilament mesh 0.006" in diameter on each side of the ring. These layers of mesh are stitched together around the ring using PTFE monofilament. The extra large oval sized patches contain inner and outer PDO monofilament rings. A single layer of expanded ePTFE is attached to the bottom primary layer of polypropylene mesh (posterior mesh). The attachment is accomplished with an interlocking stitch using PTFE monofilament. The peripheral edge of the polypropylene mesh will be heat sealed to the ePTFE layer.

E. Intended Use

The Ventrio Hernia Patch is a sterile, single use device indicated for use in the reconstruction of soft tissue deficiencies, such as for the repair of hernias. The intended use for the Ventrio Hernia Patch is the same as the predicate device, Bard Composix Kugel Hernia Patch*, with the exception of the indication for repair of chest wall defects.

Summary of Similarities and Differences in Technological Characteristics, F. Performance and Intended Use

The proposed Ventrio Hernia Patch has the same intended use, and both similar and different technological characteristics as the currently marketed Bard Composix Kugel Hernia Patch (K061314), containing the re-designed recoil ring. The differences in the proposed device include a different material for the absorbable recoil mechanism (ring), and additional mesh layers around the recoil ring as compared with the predicate device.

Both the proposed device and the predicate Bard Composix Kugel Hernia Patch ("predicate Bard") device contain two layers of mesh constructed of knitted polypropylene monefilament. The predicate Ethicon PROCEED Ventral Patch also contains polypropylene mesh (K061533) ("predicate Ethicon PROCEED"). In addition, both the proposed and the predicate Bard devices also contain a single layer of expanded polytetrafluoroethylene (ePTFE) attached to the polypropylene mesh. In both devices, the ePTFE is attached to the polypropylene mesh with an interlocking stitch using polytetrafluoroethylene (PTFE) monofilament. The peripheral edge of the polypropylene mesh is heat sealed to the ePTFE layer in both the predicate and proposed devices. The predicate W.L. Gore INFINIT Mesh (K081069) and DualMesh® EMERGE Plus Biomaterial (K022782) devices also contain an ePTFE mesh.

PREMARKET NOTIFICATION FOR THE VENTRIO HERNIA PATCH

-CONFIDENTIAL-

  • The Ventrio Hernia Patch is substantially equivalent to the modified Bard Composix Kugel Hernia Patch I the Vent 10 re-designed recoil ring covered under 510(k) K061314, cleared on June 2, 2006

2

Both the proposed device and the predicate Bard device contain polymer rings as a recoil mechanism, to ensure stability and simplicity in proper patch placement. However, the proposed device uses a fully absorbable polymer ring composed of an absorbable polydioxanone monofilament, while the ring in the predicate Bard device is a permanent polymer ring composed of extruded monofilament polyethylene terephthalate (PET). The predicate Ethicon PROCEED also includes absorbable polymer rings. In the both the proposed and predicate Bard devices, the mesh surrounding either side of the recoil ring is stitched using PTFE sewing monofilament thread. However, in the small sizes of the predicate Bard device, the mesh on both sides of the ring is ultrasonically welded in addition to being stitched with PTFE sewing monofilament thread.

The proposed device also has additional mesh layers surrounding the recoil ring. Specifically, the absorbable polymer ring has two donut shaped layers of knitted polypropylene monofilament mesh on each side of the ring stitched together with PTFE monofilament thread. These donut shaped layers of mesh are not present in the predicate Bard device.

Laboratory bench testing and in vitro and in vivo resorption studies were performed to verify that the proposed product's performance characteristics are similar to that of the predicate device.

Performance Data G.

Laboratory bench testing was performed to compare the proposed Ventrio Hernia Patch to the currently marketed Bard Composix Kugel Hernia Patch*. In addition, in-vitro and in-vivo resorption studies were also performed on the proposed device to characterize the mechanical strength and resorption of the PDO monofilament. The results show that the proposed device is as safe and effective for its intended use as the currently marketed predicate device. Therefore, based on laboratory testing and the in-vitro and in-vivo resorption data, the proposed device is substantially equivalent to the predicate device.

  • The Ventrio Hernia Patch is substantially equivalent to the modified Bard Composix Kugel Hernia Patch containing the re-designed recoil ring covered under 510(k) K061314, cleared on June 2, 2006

PREMARKET NOTIFICATION FOR THE VENTRIO HERNIA PATCH

-CONFIDENTIAL-

3

Image /page/3/Picture/2 description: The image shows the logo for the U.S. Department of Health & Human Services. The logo consists of a stylized eagle or bird-like figure with three tail feathers. The bird is positioned to the right of a circular arrangement of text. The text reads "DEPARTMENT OF HEALTH & HUMAN SERVICES . USA".

SEP 2 9 2008

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

Ms. Stephanic Baker Senior Regulatory Affairs Associate C.R. Bard, Incorporated 100 Crossings Boulevard Warwick, Rhode Island 02886

Re: K081777 Trade/Device Name: Ventrio Hernia Patch Regulation Number: 878.3300 Regulation Name: Surgical Mesh Regulatory Class: II Product Code: FTL Dated: September 11, 2008 Received: September 12, 2008

Dear Ms. Baker:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

4

Page 2 - Ms. Baker

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practicc requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

This letter will allow you to begin marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Center for Devices and Radiological Health's (CDRH's) Office of Compliance at (240) 276-0115. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding postmarket surveillance, please contact CDRH's Office of Surveillance and Biometric's (OSB's) Division of Postmarket Surveillance at (240) 276-3474. For questions regarding the reporting of device adverse events (Medical Device Reporting (MDR)), please contact the Division of Surveillance Systems at (240) 276-3464. You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (240) 276-3150 or at its Internet address http://www.fda.gov/cdrh/industry/support/index.html.

Sincerely yours.

Mark N. Mulhern

Mark N. Melkerson Director Division of General, Restorative and Neurological Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

5

INDICATION FOR USE STATEMENT

KOGI777 510(k) Number (if known):

Device Name: Ventrio Hernia Patch

Indications for Use: The Ventrio Hernia Patch is indicated for use in the reconstruction of soft tissue deficiencies, such as for the repair of hernias.

Prescription Use X (Part 21 CFR 801 Subpart D) AND/OR

Over-The-Counter Use (21 CFR 801 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Nei Records for mxm
(Division Sign-Off)

Division of Anesthesiology, General Hospital Infection Control, Dental Devices

510(k) Number: K081777