K Number
K983504
Device Name
PRECISION XTRA ADVANCED DIABETES MANAGEMENT SYSTEM, PRECISION BLOOD GLUCOSE TEST STRIPS, PRECISION XTRA B-KETONE TEST ST
Manufacturer
Date Cleared
1999-07-09

(276 days)

Product Code
Regulation Number
862.1345
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
The Precision Xtra Advanced Diabetes Management System is intended for in vitro diagnostic use (i.e. for external use only) for the quantitative measurement of glucose and/or ketone in fresh capillary whole blood. The Precision Xtra System is for home (lay user) or professional use. The Precision Xtra System may also be used for the quantitative measurement of glucose in venous, arterial, or neonatal whole blood and ketone in venous blood, provided the sample is used within 30 minutes after collection.
Device Description
The Precision™ Xtra™ Advanced Diabetes Management System for Blood Glucose and Ketone Testing utilizes amperometric biosensor technology to generate a current. The size of the current is proportional to the amount of glucose (or Beta-Hydroxybutyrate ketone) present in the sample, providing a quantitative measure of glucose (or ketone) in whole blood and control solutions.
More Information

Not Found

No
The description focuses on amperometric biosensor technology and does not mention any AI or ML components. The "Mentions AI, DNN, or ML" section is explicitly marked as "Not Found".

No.
The device is an in vitro diagnostic (IVD) device used for measuring glucose and ketone levels, which provides information for diabetes management but does not directly treat the condition.

Yes

The intended use explicitly states, "The Precision Xtra Advanced Diabetes Management System is intended for in vitro diagnostic use." The device also measures glucose and ketone levels, which are used to assess a patient's health condition related to diabetes.

No

The device description explicitly states it utilizes "amperometric biosensor technology to generate a current," which is a hardware component for measuring glucose and ketone.

Yes, this device is an IVD (In Vitro Diagnostic).

Here's why:

  • Explicit Statement in Intended Use: The "Intended Use / Indications for Use" section clearly states: "The Precision Xtra Advanced Diabetes Management System is intended for in vitro diagnostic use (i.e. for external use only)..."
  • Measurement of Analytes in Biological Samples: The device measures glucose and/or ketone in fresh capillary whole blood, venous whole blood, arterial whole blood, and neonatal whole blood. These are biological samples.
  • Quantitative Measurement: The device provides a "quantitative measurement" of these analytes.
  • External Use Only: The intended use specifies "for external use only," which is characteristic of IVD devices.

The description of the device and its function further supports its classification as an IVD, as it describes the technology used to measure the analytes in the blood sample.

N/A

Intended Use / Indications for Use

The Precision Xtra Advanced Diabetes Management System is intended for in vitro diagnostic use (i.e. for external use only) for the quantitative measurement of glucose and/or ketone in fresh capillary whole blood. The Precision Xtra is for home (lay user) or professional use.

The Precision Xtra System may also be used for the quantitative measurement of glucose in venous, arterial, or neonatal whole blood and ketone in venous blood, provided the sample is used within 30 minutes.

Product codes

CGA

Device Description

The Precision™ Xtra™ Advanced Diabetes Management System for Blood Glucose and Ketone Testing utilizes amperometric biosensor technology to generate a current. The size of the current is proportional to the amount of glucose (or Beta-Hydroxybutyrate ketone) present in the sample, providing a quantitative measure of glucose (or ketone) in whole blood and control solutions.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

Not Found

Indicated Patient Age Range

Not Found

Intended User / Care Setting

home (lay user) or professional use.

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies

The performance of the Precision Xtra Diabetes Management System was studied in the laboratory and in clinical settings by healthcare professionals and lay users. The studies demonstrated that lay users can obtain blood glucose and ketone results that are substantially equivalent to the current methods for blood glucose and ketone measurements, which include the predicate devices listed above.

Conclusion: Results of laboratory and clinical testing demonstrate that the performance of the Precision Xtra Advanced Diabetes Management System, when used according to the intended use stated above, is acceptable and comparable to the performance of the previously mentioned predicate devices for blood glucose and ketone testing. In addition, results of clinical performance testing demonstrate that trained operators and lay users obtain equivalent whole blood glucose and ketone results.

Key Metrics

Not Found

Predicate Device(s)

K963676, K945887, K962295, K971812, K911801, K850368

Reference Device(s)

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information

Not Found

§ 862.1345 Glucose test system.

(a)
Identification. A glucose test system is a device intended to measure glucose quantitatively in blood and other body fluids. Glucose measurements are used in the diagnosis and treatment of carbohydrate metabolism disorders including diabetes mellitus, neonatal hypoglycemia, and idiopathic hypoglycemia, and of pancreatic islet cell carcinoma.(b)
Classification. Class II (special controls). The device, when it is solely intended for use as a drink to test glucose tolerance, is exempt from the premarket notification procedures in subpart E of part 807 of this chapter subject to the limitations in § 862.9.

0

Precision Xtra Advanced Diabetes Ma 510(k) Submission - 10/05

Summary of Safety and Effectiveness

| Submitted by: | Denise Haley
Regulatory Affairs Specialist
MediSense, Inc.
4A Crosby Drive
Bedford, MA 01730 |
|--------------------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| Device Name: | Precision™ Xtra™ Advanced Diabetes Management System |
| Common Name: | Self-Monitoring Blood Glucose and Ketone System |
| Classification: | Glucose Test System
Class II per 21 CFR 862.1345
Ketones Test System
Class I per 21 CFR 862.1435 |
| Predicate Devices: | Precision QID® Blood Glucose Testing System--K963676
Precision QID® and Precision G® Blood Glucose Test Strip--
K945887, K962295, K971812
GDS Stat-Site Meter/GDS KETOSITE® Blood Ketone Test--
K911801
Sigma Diagnostics β-Hydroxybutyrate Procedure No. 310-UV--
K850368 |
| Description: | The Precision™ Xtra™ Advanced Diabetes Management System
for Blood Glucose and Ketone Testing utilizes amperometric
biosensor technology to generate a current. The size of the current
is proportional to the amount of glucose (or Beta-Hydroxybutyrate
ketone) present in the sample, providing a quantitative measure of
glucose (or ketone) in whole blood and control solutions. |
| Intended Use: | The Precision Xtra Advanced Diabetes Management System is
intended for in vitro diagnostic use (i.e. for external use only) for
the quantitative measurement of glucose and/or ketone in fresh
capillary whole blood. The Precision Xtra is for home (lay user) or
professional use. |

Medisense Confidential

1

The Precision Xtra System may also be used for the quantitative measurement of glucose in venous, arterial, or neonatal whole blood and ketone in venous blood, provided the sample is used within 30 minutes.

Comparison to

The Precision Xtra Advanced Diabetes Management System has Predicate Device: equivalent technological characteristics as the Precision QID Blood Glucose Testing System (K963676, K971812) and the Precision G Blood Glucose Testing System (K963676). The Precision Xtra also has the same intended use as the Precision OID and Precision G Systems for glucose testing and the GDS Ketosite Test Card on the GDS Stat-Site Meter(K911801) and Sigma B-Hydroxybutyrate Procedure 310-UV (K850368) for ketone testing.

Performance Studies:

The performance of the Precision Xtra Diabetes Management System was studied in the laboratory and in clinical settings by healthcare professionals and lay users. The studies demonstrated that lay users can obtain blood glucose and ketone results that are substantially equivalent to the current methods for blood glucose and ketone measurements, which include the predicate devices listed above.

Conclusion: Results of laboratory and clinical testing demonstrate that the performance of the Precision Xtra Advanced Diabetes Management System, when used according to the intended use stated above, is acceptable and comparable to the performance of the previously mentioned predicate devices for blood glucose and ketone testing. In addition, results of clinical performance testing demonstrate that trained operators and lay users obtain equivalent whole blood glucose and ketone results.

2

Image /page/2/Picture/1 description: The image shows the logo for the U.S. Department of Health & Human Services. The logo is circular and contains the words "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" around the perimeter. Inside the circle is an abstract image of an eagle or bird-like figure.

Food and Drug Administration 2098 Gaither Road Rockville MD 20850

JUL - 9 1999

Ms. Denise Haley Regulatory Affairs Specialist Abbott Laboratories MediSense Products 4A Crosby Drive Bedford, Massachusetts 01730-1402

Re: K983504

Trade Name: Precision™ Xtra" Advanced Diabetes Management System Regulatory Class: II Product Code: CGA Dated: April 29, 1999 Received: May 3, 1999

Dear Ms. Haley:

We have reviewed your Section 510(k) notification of intent to market the device referenced above and we have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (Premarket Approval), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 895. A substantially equivalent determination assumes compliance with the Current Good Manufacturing Practice requirements, as set forth in the Quality System Regulation (QS) for Medical Devices: General regulation (21 CFR Part 820) and that, through periodic QS inspections, the Food and Drug Administration (FDA) will verify such assumptions. Failure to comply with the GMP regulation may result in regulatory action. In addition, FDA may publish further announcements concerning your device in the Federal Register. Please note: this response to your premarket notification submission does not affect any obligation you might

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Page 2

Under the Clinical Laboratory Improvement Amendments of 1988 (CLIA-88), this device may require a CLIA complexity categorization. To determine if it does, you should contact the Centers for Disease Control and Prevention (CDC) at (770) 488-7655.

This letter will allow you to begin marketing your device as described in your 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801 and additionally 809.10 for in vitro diagnostic devices), please contact the Office of Compliance at (301) 594-4588. Additionally, for questions on the promotion and advertising of your device, please contact the Office of Compliance at (301) 594-4639. Also, please note the regulation entitled, "Misbranding by reference to premarket notification"(21 CFR 807.97). Other general information on your responsibilities under the Act may be obtained from the Division of Small Manufacturers Assistance at its toll-free number (800) 638-2041 or (301) 443-6597, or at its internet address "http://www.fda.gov/cdrh/dsma/dsmamain.html".

Sincerely yours,

Steven Putman

Steven I. Gutman, M.D, M.B.A. Director Division of Clinical Laboratory Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

4

INDICATIONS FOR USE FORM

510(k) Number (if known):

Device Name: Precision™ Xtra™ Advanced Diabetes Management System

Indications For Use:

The Precision Xtra Advanced Diabetes Management System is intended for in vitro diagnostic use (i.e. for external use only) for the quantitative measurement of glucose and/or ketone in fresh capillary whole blood. The Precision Xtra System is for home (lay user) or professional use.

The Precision Xtra System may also be used for the quantitative measurement of glucose in venous, arterial, or neonatal whole blood and ketone in venous blood, provided the sample is used within 30 minutes after collection.

Dean Cooper
(Division Sign-Off)
Division of Clinical Laikrak
510(k) Number K983504

(PLEASE DO NOT WRITE BELOW THIS LINE--CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

or

Prescription Use (Per 21 CFR 801.108) Over-The-Counter Use