K Number
K180598
Manufacturer
Date Cleared
2018-08-08

(154 days)

Product Code
Regulation Number
872.3640
Panel
Dental
Reference & Predicate Devices
Predicate For
N/A
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

UNIQA® Dental Implants System is indicated for use in surgical and restorative applications for placement in the bone of the upper or lower jaw to provide support for prosthetic devices, such as artificial teeth, in order to restore the patient's chewing function. UNIQA® Dental Implants System is indicated also for immediate loading when good primary stability is achieved and with appropriate occlusal loading.

UNIQA Conical Connection Implants: #UCI & #UC7 are to be used only with straight abutments.

Conical Mini implants (Ø3.3mm) are indicated for use in surgical and restorative applications for placement only in the mandibular central, lateral incisor and maxillary lateral incisor regions of partially edentulous jaws, to provide support for prosthetic devices such as artificial teeth, in order to restore the patient chewing function. Mandibular central and lateral incisors must be splinted if using two or more narrow implants adjacent to one another.

Device Description

UNIQA® Dental Implant System is consist of endosseous form dental implants, internal hex implants, tapered design; cover screws, healing caps and abutment systems; The Dental Implants provided in two types of design:(a) Conical Hex; (b) Internal Hex; Each implant design is available in two options of surface treatment (1) Pure & Porous, P&P which consists of Hydroxyapatite and Calcium Phosphates; or (2) SBA - which consists of sand blast large particles with acid etched;

AI/ML Overview

The provided text describes UNIQA® Dental Implants System and its comparison to predicate devices, but it does not contain information about acceptance criteria for a study or the study details to prove the device meets acceptance criteria related to a diagnostic or AI-assisted product.

The document is a 510(k) premarket notification for a medical device (dental implants and abutments). It focuses on demonstrating substantial equivalence to legally marketed predicate devices, primarily through comparison of:

  • Intended Use and Indications for Use: The UNIQA® system has the same general indications as its primary predicate, with some specific details for certain implant types (e.g., mini implants for specific jaw regions, use with straight abutments) matching reference devices.
  • Technological Characteristics: This includes thread design, measurements (diameter/length), connection type, material (Titanium Alloy Ti6Al4V ELI), surface treatment (Pure & Porous, P&P or SBA), self-tapping feature, sterilization method (Gamma Ray), and packaging (Double packaging).
  • Performance Testing: Bench tests like fatigue testing (ISO 14801), sterilization validation (ISO 11137, ISO 17665), shelf life (ASTM F-1980), biocompatibility (ISO 10993-5), and surface cleanliness are mentioned. These tests are performed to ensure the device's safety and effectiveness in relation to its physical and material properties, rather than its diagnostic performance.

Therefore, I cannot provide the requested information about acceptance criteria and study details for a diagnostic or AI-assisted device, as this information is not present in the provided text.

The document explicitly states: "Clinical Testing - No clinical data is included in this submission." This confirms that no studies involving human subjects were conducted or reported for this submission to establish a clinical performance metric.

To reiterate, the provided text does not contain:

  • A table of acceptance criteria for diagnostic performance metrics (e.g., sensitivity, specificity, accuracy).
  • Reported device performance values for diagnostic tasks.
  • Sample size used for a test set in a diagnostic study.
  • Data provenance for a diagnostic study.
  • Number of experts or their qualifications for establishing ground truth in a diagnostic study.
  • Adjudication methods for ground truth in a diagnostic study.
  • Information on a multi-reader multi-case (MRMC) comparative effectiveness study or related effect sizes.
  • Standalone performance (algorithm only without human-in-the-loop performance) for a diagnostic algorithm.
  • Type of ground truth used for a diagnostic study (expert consensus, pathology, etc.).
  • Sample size for a training set of a diagnostic algorithm.
  • How ground truth for a training set of a diagnostic algorithm was established.

{0}------------------------------------------------

Image /page/0/Picture/0 description: The image contains the logos of the U.S. Department of Health & Human Services and the U.S. Food & Drug Administration (FDA). The Department of Health & Human Services logo is on the left, featuring a stylized human figure. To the right of that is the FDA logo, which includes the letters "FDA" in a blue square, followed by the words "U.S. FOOD & DRUG ADMINISTRATION" in blue text.

August 8, 2018

UNIQA DENTAL LTD. % Daniela Levy Regulatory Consultant Sterling Medical Registration 22815 Ventura Blvd. Woodland Hills, California 91364

Re: K180598

Trade/Device Name: UNIOA® Dental Implants System Regulation Number: 21 CFR 872.3640 Regulation Name: Endosseous Dental Implant Regulatory Class: Class II Product Code: DZE, NHA Dated: May 14, 2018 Received: May 23, 2018

Dear Daniela Levy:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you, however, that device labeling must be truthful and not misleading.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

{1}------------------------------------------------

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); medical device reporting of medical device-related adverse events) (21 CFR 803); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21 CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to http://www.fda.gov/MedicalDevices/Safety/ReportaProblem/default.htm.

For comprehensive regulatory information about mediation-emitting products, including information about labeling regulations, please see Device Advice (https://www.fda.gov/MedicalDevices/DeviceRegulationandGuidance/) and CDRH Learn (http://www.fda.gov/Training/CDRHLearn). Additionally, you may contact the Division of Industry and Consumer Education (DICE) to ask a question about a specific regulatory topic. See the DICE website (http://www.fda.gov/DICE) for more information or contact DICE by email (DICE@fda.hhs.gov) or phone (1-800-638-2041 or 301-796-7100).

Sincerely,

Andrew I. Steen -S

for Tina Kiang, Ph.D. Acting Director Division of Anesthesiology, General Hospital, Respiratory, Infection Control, and Dental Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

{2}------------------------------------------------

Image /page/2/Picture/0 description: The image shows the logo for UNIQA Dental. The word "UNIQA" is in large, green, sans-serif font, with a small, dark red square above the "I". Below "UNIQA" is the word "DENTAL" in a smaller, green, sans-serif font. The logo is simple and clean, with a focus on the company name.

SECTION 4

Indication for Use Statement

510(k) Number (if known): K180598 Device Name: UNIQA® Dental Implants System Indications for Use (Describe)

Indications for Use:

UNIQA® Dental Implants System is indicated for use in surgical and restorative applications for placement in the bone of the upper or lower jaw to provide support for prosthetic devices, such as artificial teeth, in order to restore the patient's chewing function. UNIQA® Dental Implants System is indicated also for immediate loading when good primary stability is achieved and with appropriate occlusal loading.

UNIQA Conical Connection Implants: #UCI & #UC7 are to be used only with straight abutments.

Conical Mini implants (Ø3.3mm) are indicated for use in surgical and restorative applications for placement only in the mandibular central, lateral incisor and maxillary lateral incisor regions of partially edentulous jaws, to provide support for prosthetic devices such as artificial teeth, in order to restore the patient chewing function. Mandibular central and lateral incisors must be splinted if using two or more narrow implants adjacent to one another.

Type of Use (Select one or both, as applicable)

区Prescription Use (Part 21 CFR 801 Subpart D)

□ Over-The-Counter Use(21 CFR 801 Subpart

PLEASE DO NOT WRITE BELOW THIS LINE - CONTINUE ON A SEPARATE PAGE IF NEEDED

FOR FDA USE ONLY

Concurrence of Center for Devices and Radiological Health (CDRH) (Signature)

{3}------------------------------------------------

Image /page/3/Picture/0 description: The image shows the logo for UNIQA Dental. The word "UNIQA" is in large, green, sans-serif font, with a small, dark red square above the "I". Below "UNIQA" is the word "DENTAL" in a smaller, green, sans-serif font. The overall design is simple and modern.

SECTION 5 -

510(k) Number K180598

  • 1 Type of Submission Premarket Notification (21 CFR 807.90(e)) 510(k) Traditional
2Submission OwnerUNIQA DENTAL LTD.
Dima Goberman - CEO
26 Tom Lantos blvd., Alon Center
Netanya 4276001
Israel
Tel : 972-77-7827367
Fax : 972-73-7372636
3Official CorrespondentContact PersonSterling Medical RegistrationDaniela Levy - Regulatory Consultant
22815 Ventura blvd.
Woodland Hills, CA 91364
Phone: 1-213-787-3027
Email: sterlingmedical2017@gmail.com
4Date PreparedTuesday, August 7, 2018
5Device Trade NameUNIQA® Dental Implants System
6Regulation DescriptionEndosseous Dental Implants Abutment
7ClassificationPrimary Product Code: DZE
Device Name : Implant, endosseous, root-form
Regulation No : 872.3640
Class : II
Panel : Dental
Secondary Product Code: NHA
8Reason for the Premarket Notification Submission: New Device
9Identification of Legally Marketed Predicate Devices :
  • Primary Predicate:
    MIS Implant Technologies Ltd Implants System K040807;

{4}------------------------------------------------

Reference Devices:

MIS Implant Technologies Ltd Implants System K163349; Astra Tech AB OsseoSpeed TX K101732 Nobel Biocare Multi Unit Abutment K072570; A.B. Dental Devices Ltd K132125, K112440; Dentin Dental Implants System K120530; in terms of intended use, indication for use, raw material, technological characteristics and performance. The primary predicate and referenced devices are Class II medical devices.

  • 10 Device Description:
    UNIQA® Dental Implant System is consist of endosseous form dental implants, internal hex implants, tapered design; cover screws, healing caps and abutment systems; The Dental Implants provided in two types of design:(a) Conical Hex; (b) Internal Hex; Each implant design is available in two options of surface treatment (1) Pure & Porous, P&P which consists of Hydroxyapatite and Calcium Phosphates; or (2) SBA - which consists of sand blast large particles with acid etched;

Dental Implants:

Conical Implant, Pure & Porous, P&P -

Measurements: Diameters 3.3, 3.75, 4.2, 5.0 mm with lengths 8, 10, 11.5, 13, 16 mm; Conical Implant, SBA -

Measurements: Diameters 3.3, 3.75, 4.2, 5.0 mm with lengths 8, 10, 11.5, 13, 16 mm; Conical Implant, Internal Hex, Pure & Porous, P&P -

Measurements: Diameters 3.3, 3.75, 4.2, 5.0 mm with lengths 8, 10, 11.5, 13, 16 mm; Conical Implant, Internal Hex, SBA -

Measurements: Diameters 3.3, 3.75, 4.2, 5.0 mm with lengths 8, 10, 11.5, 13, 16 mm; Dental Abutments:

Dental Abutments Internal Hex Connection: Locator Abutments, Angled Anatomic Abutments 15°, 25°, Angled Abutments 15°, 25°, Angled Multi Unit Abutments D-type 179,300 (provided also as set), Temporary Sleeves for Multi Unit D-type, Straight Multi Unit Abutments D-type, Ball attachment abutments, Healing Caps (Narrow, Regular, Wide), Straight anatomic abutment, Straight abutments (Regular, Wide), Straight

{5}------------------------------------------------

abutment with shoulder( Reqular, Wide), Snap on Transfer abutments, Straight Multi Unit Abutments D-type.

Dental Abutments Conical Connection: Healing Caps (Mini, Regular), Transfer Abutments (Mini, Regular), Transfer Abutment Regular, Straight Multi Unit Abutments C-type, Sleeves for Multi Unit C-type.

  • 11 Indication for Use:
    UNIQA® Dental Implants System is indicated for use in surgical and restorative applications for placement in the bone of the upper or lower jaw to provide support for prosthetic devices, such as artificial teeth, in order to restore the patient's chewing function. UNIQA® Dental Implants System is indicated also for immediate loading when good primary stability is achieved and with appropriate occlusal loading.

UNIQA Conical Connection Implants: #UCI & #UC7 are to be used only with straight abutments.

Conical Mini implants (Ø3.3mm) are indicated for use in surgical and restorative applications for placement only in the mandibular central, lateral incisor and maxillary lateral incisor regions of partially edentulous jaws, to provide support for prosthetic devices such as artificial teeth, in order to restore the patient chewing function. Mandibular central and lateral incisors must be splinted if using two or more narrow implants adjacent to one another.

  • 12 Performance Standards or Special Controls
    • . ISO 7405 Second edition 2008-12-15 Dentistry - Evaluation of biocompatibility of medical devices used in dentistry.
    • ISO 5832-3:1996 Implants for surgery -- Metallic materials -- Part 3: Wrought . titanium 6-aluminium 4-vanadium alloy.
    • . ISO 14801 Second edition 2007-11-15 Dentistry-Implants-Dynamic fatigue test for endosseous dental implants.
    • . ISO 11137-1:2006 Sterilization of health care products -- Radiation -- Part 1: Requirements for development, validation and routine control of a sterilization process for medical devices

{6}------------------------------------------------

  • ISO 11737-2: 2009 Sterilization of medical devices -- Microbiological methods --Part 2: Tests of sterility performed in the definition, validation and maintenance of a sterilization process
  • ASTM F-1980 16 Standard Guide for Accelerated Aging of Sterile Barrier Systems . for Medical Devices
  • . ISO 17665-1:2006 Sterilization of health care products - Moist heat - Part 1: Requirements for the development, validation and routine control of a sterilization process for medical devices
  • . ISO 17665-2:2009 Sterilization of health care products -- Moist heat -- Part 2: Guidance on the application of ISO 17665-1
  • . ISO 10993-5:2009 Biological evaluation of medical devices -- Part 5: Tests for in vitro cytotoxicity
  • FDA guidance document: Class II Special Controls Guidance Document: Root-form . Endosseous Dental Implants and Endosseous Dental Abutments - Guidance for Industry and FDA Staff.
  • Chemical and SEM analysis performed on implants per Class II Special Controls . Guidance Document: Root-form Endosseous Dental Implants and Endosseous Dental Abutments - Guidance for Industry and FDA Staff.
  • Endotoxin batch testing protocol per FDA Guidance Document Submission and . Review of Sterility Information in Premarket Notification (510(k)) Submissions for Devices Labeled as Sterile.

{7}------------------------------------------------

13 Substantial Equivalence

CharacteristicConical Implant, Pure& Porous, P&P Cat #UCIMIS - SEVEN ImplantsMIS V3 ConicalConnection implantsOsseoSpeed TX SA.B. DentalImplant systemDENTIN DentalImplant system
Primary PredicateReference DeviceReference DeviceReferenceDeviceReference Device
510(k) numberK180598K040807K163349K101732K132125K120530
ManufacturerUNIQA Dental Ltd.MIS ImplantsTechnologies ItdMIS ImplantsTechnologies ItdAstra Tech ABA.B. DentalDevice ItdDENTIN ImplantsTechnologies Ltd
Product NameConical Implant, Pure &Porous, P&PSEVEN ImplantsMIS V3 ConicalConnection DentalImplant SystemOsseoSpeed TX S15 ConicalImplantRAPID Implant
Thread DesignTapered, Double ThreadTapered, DoubleThreadTapered, DoubleThreadCylindrical taperedapex, threadedTapered, DoubleThreadTapered
Measurements:Ø / Length mm3.3 Ø: 8 ,10, 11.5, 13,163.75 Ø: 8 ,10, 11.5, 13,164.2 Ø: 8 ,10, 11.5, 13,165.0 Ø: 8 ,10, 11.5, 13,163.75 Ø: 8 ,10, 11.5,13,164.2 Ø: 8 ,10, 11.5, 13,165.0 Ø: 8 ,10, 11.5, 13,163.3 Ø: 10, 11.5, 13, 164.3 Ø: 8 ,10, 11.5, 13,164.9 Ø: 8 ,10, 11.5, 13,165.0 Ø: 8 ,10, 11.5, 13,163.0 Ø: 11, 13, 153.5 Ø: 8, 9, 11, 13, 15,174.0 Ø: 6, 8, 9, 11,13,15, 175.0 Ø: 9, 11, 13, 15, 173.5 Ø: 8 ,10,11.5, 13, 163.3 Ø: 8 ,10, 11.5, 13,163.75 Ø: 8 ,10, 11.5,13, 164.2 Ø: 8 ,10, 11.5, 13,165.0 Ø: 7, 8 ,10, 11.5,136.0 Ø: 7, 8 ,10, 11.5,13
ConnectionTypeInternal conicalconnection, coneangulation 22°Internal hexInternal conicalconnection, coneangulation 12°Internal conicalconnection, coneangulation 21ºInternal HexInternal Hex
MaterialTitanium Alloy Ti6Al4VELITitanium Alloy Ti6Al4VELITitanium Alloy Ti6Al4VELITitanium grade 4Titanium AlloyTi6Al4V ELITitanium Alloy Ti6Al4VELI
SurfaceTreatmentClean&Porous, P&P(Hydroxyapatite andCalcium Phosphates)Sand Blast and acid-etchedSand Blast and acid-etchedTiO2-blastedfluoridemodified surfaceHydroxyapatiteand CalciumPhosphatesSand Blast & AcidEtched
Self tappingYesYesYesYesYesYes
Indication for UseUNIQA Dental ® Dental ImplantsThe MIS Dental Implant SystemMIS V3 Connection Dental Implant SystemThe OsseoSpeed ImplantsA.BDENTAL DEVICES®DENTIN® Dental Implants System
System is indicated for use in surgical and restorative applications for placement in the bone of the upper or lower jaw to provide support for prosthetic devices, such as artificial teeth, in order to restore the patient's chewing function. UNIQA Dental ® Dental Implants System is indicated also for immediate loading when good primary stability is achieved and with appropriate occlusal loading. UNIQA Conical Connection Implants: #UCI & #UC7 are to be used only with straight abutments. Conical Mini implants (Ø3.3mm) are indicated for use in surgical and restorative applications for placement only in the mandibular central, lateral incisor and maxillary lateral incisor regions of partially edentulous jaws, to provide support for prosthetic devices such as artificial teeth, in order to restore the patient chewing function. Mandibular central and lateral incisors must be splinted if using two oris intended to be surgically placed in the bone of the upper or lower jaw arches to provide support for prosthetic devices, such as artificial teeth, in order to restore masticatory function.is intended to be surgically placed in the bone of the upper or lower jaw arches to provide support for prosthetic devices, such as artificial teeth, in order to restore masticatory function. When a one-stage surgical procedure is applied, the implant may be immediately loaded when good primary stability is achieved and the occlusal load is appropriate. Narrow implants (Ø3.3mm) are indicated for use in surgical and restorative applications for placement only in the mandibular central, lateral incisor and maxillary lateral incisor regions of partially edentulous jaws, to provide support for prosthetic devices such as artificial teeth, in order to restore the patient chewing function. Mandibular central and lateral incisors must be splinted if using two or more narrow implants adjacent to one another.are intended to be used: to replace missing teeth in single or multiple unit applications within the mandible or maxillafor immediate placement in extraction sites and partially or completely healed alveolar ridge situationsfor both one- and two stage surgical proceduresespecially well in soft bone applications where implants with other implant surface treatments may be less effectivetogether with immediate loading protocol in all indications, except in single tooth situations in soft bone (type IV) where implant stability may be difficult to obtain and immediate loading may not be appropriatetogether with immediate loading protocol for single tooth restorations on implants 8 mm or longerwith its 3.0 S product line for maxillary lateral incisors and mandibular lateral and central incisors.Dental Implants System is indicated for use in surgical and restorative applications for placement in the bone of the upper or lower jaw to provide support for prosthetic devices, such as artificial teeth, in order to restore the patient's chewing function. A.B. DENTAL DEVICES® Dental Implants System is indicated also for immediate loading when good primary stability is achieved and with appropriate occlusal loading. Two Stage Implants: I2,I5,I6BI. One Stage: I6, I6b, I6B. One Stage & One-Piece 3.0 mm diameter implants: I6, I6B, I6BI, are intended foris indicated for use in surgical and restorative applications for placement in the bone of the upper or lower jaw to provide support for prosthetic devices, such as artificial teeth, in order to restore the patient's chewing function. DENTIN® Dental Implants System is indicated also for immediate loading when good primary stability is achieved and with appropriate occlusal loading. Two Stage Implants: CLASSIC, RAPID, PRESTIGE. One Stage Implants: ONE PIECE DENTIN® ONEPIECE Implants 3.0 mmd are intended for placement at the mandibular central and lateral incisors and maxillary and lateral incisors. Indicated also for denture stabilization using multiple implants.
Indication forUseplacement at themandibularcentral andlateral incisorsand maxillaryand lateralincisors.Indicated alsofor denturestabilizationusing multipleimplants. Onestage & One-Piece 2.4 mmdiameterimplants fortemporary use orlong term use:I6, I6b, permitimmediate splintstability and longterm fixation ofnew or existingcrown, bridgeand prosthesis.P14 AngulatedAbutmentAdapter is to beused withimplant diameter4.2mm andhigher.
Self tappingGamma Ray
SterilizationGamma RayDouble packagingGamma RayGamma RayGamma RayGamma Ray
PackagingDouble packagingDouble packagingDouble packagingDoublepackagingDouble packaging

{8}------------------------------------------------

{9}------------------------------------------------

Image /page/9/Picture/0 description: The image shows the logo for UNIQA Dental. The word "UNIQA" is in large, green, sans-serif font, with a small maroon square above the "I". Below "UNIQA" is the word "DENTAL" in a smaller, green, sans-serif font. The logo is simple and modern.

{10}------------------------------------------------

CharacteristicConical Implant, SBACat # UC7MIS - SEVEN ImplantsMIS V3 ConicalConnection implantsOsseoSpeed TX SDENTIN Dental Implantsystem
Primary PredicateReference DeviceReference DeviceReference Device
510(k) numberK180598K040807K163349K101732K120530
ManufacturerUNIQA Dental Ltd.MIS ImplantsTechnologies ItdMIS ImplantsTechnologies ItdAstra Tech ABDENTIN ImplantsTechnologies Ltd
Product NameConical Implant, SBASEVEN ImplantsMIS V3 ConicalConnection DentalImplant SystemOsseoSpeed TX SRAPID Implant
Thread DesignTapered, Double ThreadTapered, Double ThreadTapered, Double ThreadCylindrical tapered apex,threadedTapered
Measurements:Ø / Length mm3.3 Ø: 8, 10, 11.5, 13, 163.75 Ø: 8, 10, 11.5, 13, 164.2 Ø: 8, 10, 11.5, 13, 165.0 Ø: 8, 10, 11.5, 13, 163.75 Ø: 8, 10, 11.5, 13, 164.2 Ø: 8, 10, 11.5, 13, 165.0 Ø: 8, 10, 11.5, 13, 163.3 Ø: 10, 11.5, 13, 164.3 Ø: 8, 10, 11.5, 13,164.9 Ø: 8, 10, 11.5, 13,163.0 Ø: 11, 13, 153.5 Ø: 8, 9, 11, 13, 15, 174.0 Ø: 6, 8, 9, 11, 13, 15,175.0 Ø: 9, 11, 13, 15, 173.3 Ø: 8, 10, 11.5, 13, 163.75 Ø: 8, 10, 11.5, 13, 164.2 Ø: 8, 10, 11.5, 13, 165.0 Ø: 7, 8, 10, 11.5, 136.0 Ø: 7, 8, 10, 11.5, 13
ConnectionTypeInternal conical connection,cone angulation 22°Internal hexInternal conicalconnection, coneangulation 12°Internal conicalconnection, coneangulation 21°Internal Hex
MaterialTitanium Alloy Ti6Al4V ELITitanium Alloy Ti6Al4V ELITitanium Alloy Ti6Al4VELITitanium grade 4Titanium Alloy Ti6Al4V ELI
SurfaceTreatmentSand Blast and acid-etchedSand Blast and acid-etchedSand Blast and acid-etchedTiO2-blastedfluoridemodified surfaceSand Blast & Acid Etched
Self tappingYesYesYesYesYes

{11}------------------------------------------------

Indication forUNIQA Dental ® DentalThe MIS Dental ImplantMIS V3 ConicalThe OsseoSpeed implantsDENTIN® Dental Implants
UseImplantsSystemSystem is intended to beConnection Dentalare intended to be used:System is indicated for use
indicated for use in surgicalsurgically placed in theImplant System• to replace missing teethinin surgical and restorative
and restorative applicationsbone of the upper orintended to be surgicallysingle or multiple unitapplications for placement
for placement in the bone oflower jaw arches toplaced in the bone ofapplications within thein the bone of the upper or
the upper or lower jaw toprovide support forthe upper or lower jawmandible or maxilla • forlower jaw to provide support
provide support forprosthetic devices, sucharches to provideimmediate placement infor prosthetic devices, such
prosthetic devices, such asas artificial teeth, in ordersupport for prostheticextraction sites andas artificial teeth, in order to
artificial teeth, in order toto restore masticatorydevices, such aspartially or completelyrestore the patient's
restore the patient'sfunction.artificial teeth, in orderhealed alveolar ridgechewing function. DENTIN®
chewing function. UNIQAto restore masticatorysituations •for both one-Dental Implants System is
Dental ® Dental Implantsfunction. When a one-and two stage surgicalindicated also for immediate
System is indicated also forstage surgicalprocedures • especiallyloading when good primary
immediate loading whenprocedure is applied,well in soft bonestability is achieved and
good primary stability isthe implant may beapplications wherewith appropriate occlusal
achieved and withimmediately loadedimplants with other implantloading.
appropriate occlusalwhen good primarysurface treatments may beTwo Stage Implants:
loading.stability is achieved andless effective • togetherCLASSIC, RAPID,
UNIQA Conical Connectionthe occlusal load iswith immediate loadingPRESTIGE.
Implants: #UCI & #UC7 areappropriate. Narrowprotocol in all indications,One Stage Implants: ONE
to be used only with straightimplants (Ø3.3mm) areexcept in single toothPIECE
abutments.indicated for use insituations in soft boneDENTIN® ONEPIECE
Conical Mini implantssurgical and restorative(type IV) where implantImplants 3.0 mmd are
(Ø3.3mm) are indicated forapplications forstability may be difficult tointended for placement at
use in surgical andplacement only in theobtain and immediatethe mandibular central and
restorative applications formandibular central,loading may not belateral incisors and
placement only in thelateral incisor andappropriate • together withmaxillary and lateral
mandibular central, lateralmaxillary lateral incisorimmediate loading protocolincisors. Indicated also for
incisor and maxillary lateralregions of partiallyfor single tooth restorationsdenture stabilization using
incisor regions of partiallyedentulous jaws, toon implants 8 mm ormultiple implants.
edentulous jaws, to provideprovide support forlonger • with its 3.0 S
support for prostheticprosthetic devices suchproduct line for maxillary
devices such as artificialas artificial teeth, inlateral incisors and
teeth, in order to restore theorder to restore themandibular lateral and
patient chewing function.patient chewingcentral incisors.
Mandibular central andfunction. Mandibular
lateral incisors must becentral and lateral
splinted if using two orincisors must be
more narrow implantssplinted if using two or
adjacent to one another.more narrow implants
adjacent to one another.

{12}------------------------------------------------

Self tapping
SterilizationGamma RayGamma RayGamma RayGamma RayGamma Ray
PackagingDouble packagingDouble packagingDouble packagingDouble packagingDouble packaging
CharacteristicConical Implant, Internal Hex, Pure& Porous, P&PCat# USIMIS - SEVEN ImplantsA.B. Dental Devices LtdDENTIN Dental Implantsystem
510(k) numberK180598K040807K132125K120530
ManufacturerUNIQA Dental Ltd.MIS Implants Technologies ItdA.B. Dental Device ItdDENTIN ImplantsTechnologies Ltd
Product NameConical Implant, Internal Hex, Pure &Porous, P&PSEVEN ImplantsI5 Conical ImplantRAPID Implant
Thread DesignTapered, Double ThreadTapered, Double ThreadTapered, Double ThreadTapered
Measurements:Ø / Length mm3.3 Ø: 8 ,10, 11.5, 13, 163.75 Ø: 8 ,10, 11.5, 13, 164.2 Ø: 8 ,10, 11.5, 13, 165.0 Ø: 8 ,10, 11.5, 13, 163.75 Ø: 8 ,10, 11.5, 13,164.2 Ø: 8 ,10, 11.5, 13, 165.0 Ø: 8 ,10, 11.5, 13, 163.5 Ø: 8 ,10, 11.5, 13, 163.3 Ø: 8 ,10, 11.5, 13, 163.75 Ø: 8 ,10, 11.5, 13, 164.2 Ø: 8 ,10, 11.5, 13, 165.0 Ø: 7, 8 ,10, 11.5, 136.0 Ø: 7, 8 ,10, 11.5, 13
Connection TypeInternal hexInternal hexInternal HexInternal Hex
MaterialTitanium Alloy Ti6Al4V ELITitanium Alloy Ti6Al4V ELITitanium Alloy Ti6Al4V ELITitanium Alloy Ti6Al4V ELI
Surface TreatmentClean&Porous, P&P(Hydroxyapatite and Calcium)Phosphates)Sand Blast and acid-etchedHydroxyapatite and CalciumPhosphatesSand Blast & Acid Etched
Self tappingYesYesYesYes

{13}------------------------------------------------

Indication for UseUNIQA Dental ® Dental ImplantsSystem is indicated for use insurgical and restorative applicationsfor placement in the bone of theupper or lower jaw to provide supportfor prosthetic devices, such asartificial teeth, in order to restore thepatient's chewing function. UNIQADental ® Dental Implants System isindicated also for immediate loadingwhen good primary stability isachieved and with appropriateocclusal loading.UNIQA Conical Connection Implants:#UCI & #UC7 are to be used onlywith straight abutments.Conical Mini implants (Ø3.3mm) areindicated for use in surgical andrestorative applications for placementonly in the mandibular central, lateralincisor and maxillary lateral incisorregions of partially edentulous jaws,to provide support for prostheticdevices such as artificial teeth, inorder to restore the patient chewingfunction. Mandibular central andlateral incisors must be splinted ifusing two or more narrow implantsadjacent to one another.The MIS Dental Implant System isintended to be surgically placed inthe bone of the upper or lower jawarches to provide support forprosthetic devices, such asartificial teeth, in order to restoremasticatory function.A.BDENTAL DEVICES® Dental Implants System isindicated for use in surgical and restorative applications forplacement in the bone of the upper or lower jaw to providesupport for prosthetic devices, such as artificial teeth, in orderto restore the patient's chewingfunction. A.B. DENTAL DEVICES® Dental ImplantsSystem is indicated also for immediate loading when goodprimary stability is achieved and with appropriate occlusalloading. Two Stage Implants:I2,I5,I6BI. One Stage: I6, I6b, I6B. One Stage & One-Piece3.0 mm diameter implants: I6, I6B, I6BI, are intended forplacement at the mandibular central and lateral incisors andmaxillary and lateral incisors. Indicated also for denturestabilization using multiple implants. One stage & One-Piece2.4 mm diameter implants for temporary use or long term use: I6, I6b, permitimmediate splint stability and long term fixation of new orexisting crown, bridge and prosthesis. P14 AngulatedAbutment Adapter is to be used with implant diameter4.2mm and higher.DENTIN® Dental Implants System is indicated for use insurgical and restorative applications for placement inthe bone of the upper or lower jaw to provide supportfor prosthetic devices, such as artificial teeth, in order torestore the patient's chewing function. DENTIN® DentalImplants System is indicated also for immediate loadingwhen good primary stability is achieved and withappropriate occlusal loading. Two Stage Implants:CLASSIC, RAPID, PRESTIGE.One Stage Implants: ONE PIECE DENTIN® ONEPIECEImplants 3.0 mmd are intended for placement at themandibular central and lateral incisors and maxillaryand lateral incisors. Indicated also for denture stabilizationusing multiple implants
Self tapping
SterilizationGamma RayGamma RayGamma RayGamma Ray
PackagingDouble packagingDouble packagingDouble packagingDouble packaging
CharacteristicConical Implant, Internal Hex, SBACat# US7MIS - SEVEN ImplantsDENTIN Dental Implant system
Primary PredicateReference Device
510(k) numberK180598K040807K120530
ManufacturerUNIQA Dental Ltd.MIS Implants Technologies ItdDENTIN Implants Technologies Ltd
Product NameConical Implant, Internal Hex, SBASEVEN ImplantsRAPID Implant
Thread DesignTapered, Double ThreadTapered, Double ThreadTapered
Measurements:Ø / Length mm3.3 Ø: 8, 10, 11.5, 13, 163.75 Ø: 8, 10, 11.5, 13, 164.2 Ø: 8, 10, 11.5, 13, 165.0 Ø: 8, 10, 11.5, 13, 163.75 Ø: 8, 10, 11.5, 13, 164.2 Ø: 8, 10, 11.5, 13, 165.0 Ø: 8, 10, 11.5, 13, 163.3 Ø: 8, 10, 11.5, 13, 163.75 Ø: 8, 10, 11.5, 13, 164.2 Ø: 8, 10, 11.5, 13, 165.0 Ø: 7, 8, 10, 11.5, 136.0 Ø: 7, 8, 10, 11.5, 13
Connection TypeInternal hexInternal hexInternal Hex
MaterialTitanium Alloy Ti6Al4V ELITitanium Alloy Ti6Al4V ELITitanium Alloy Ti6Al4V ELI
Surface TreatmentSand Blast and acid-etchedSand Blast and acid-etchedSand Blast & Acid Etched
Self tappingYesYesYes

{14}------------------------------------------------

{15}------------------------------------------------

Indication for UseUNIQA Dental ® Dental Implants System isindicated for use in surgical and restorativeapplications for placement in the bone of theupper or lower jaw to provide support forprosthetic devices, such as artificial teeth, inorder to restore the patient's chewingfunction. UNIQA Dental ® Dental ImplantsSystem is indicated also for immediateloading when good primary stability isachieved and with appropriate occlusalloading.UNIQA Conical Connection Implants: #UCI &#UC7 are to be used only with straightabutments.Conical Mini implants (Ø3.3mm) are indicatedfor use in surgical and restorative applicationsfor placement only in the mandibular central,lateral incisor and maxillary lateral incisorregions of partially edentulous jaws, toprovide support for prosthetic devices such asartificial teeth, in order to restore the patientchewing function. Mandibular central andlateral incisors must be splinted if using two ormore narrow implants adjacent to oneanother.The MIS Dental Implant System is intendedto be surgically placed in the bone of theupper or lower jaw arches to providesupport for prosthetic devices, such asartificial teeth, in order to restoremasticatory function.DENTIN® Dental Implants System isindicated for use in surgical and restorativeapplications for placement in the bone of theupper or lower jaw to provide support forprosthetic devices, such as artificial teeth, inorder to restore the patient's chewingfunction. DENTIN® Dental Implants Systemis indicated also for immediate loading whengood primary stability is achieved and withappropriate occlusal loading.Two Stage Implants: CLASSIC, RAPID,PRESTIGE.One Stage Implants: ONE PIECEDENTIN® ONEPIECE Implants 3.0 mmdare intended for placement at themandibular central and lateral incisors andmaxillary and lateral incisors. Indicated alsofor denture stabilization using multipleimplants.
Self tapping
SterilizationGamma RayGamma RayGamma Ray
PackagingDouble packagingDouble packagingDouble packaging

{16}------------------------------------------------

Image /page/16/Picture/0 description: The image shows the logo for UNIQA Dental. The word "UNIQA" is in large, green, sans-serif font, with a small, dark red square above the "I". Below "UNIQA" is the word "DENTAL", also in green, sans-serif font, but smaller than "UNIQA". The logo is simple and modern.

Dental Abutments

UNIQA Dental Abutments
Company / 510kUNIQA Dental Itd K180598MIS K040807
Primary Predicate
Product NameLocator Abutments # ULARLocator Abutments
Indication for UseUNIQA Dental ®Dental Implants System isindicated for use in surgical and restorativeapplications for placement in the bone of the upperor lower jaw to provide support for prostheticdevices, such as artificial teeth, in order to restorethe patient's chewing function. UNIQA Dental ®Dental Implants System is indicated also forimmediate loading when good primary stability isachieved and with appropriate occlusal loading.UNIQA Conical Connection Implants: #UCI & #UC7are to be used only with straight abutments.Conical Mini implants (Ø3.3mm) are indicated foruse in surgical and restorative applications forplacement only in the mandibular central, lateralincisor and maxillary lateral incisor regions ofpartially edentulous jaws, to provide support forprosthetic devices such as artificial teeth, in order torestore the patient chewing function. Mandibularcentral and lateral incisors must be splinted if usingtwo or more narrow implants adjacent to oneanother.The MIS Dental Implant System is intended to besurgically placed in the bone of the upper or lowerjaw arches to provide support for prostheticdevices, such as artificial teeth, in order to restoremasticatory function.
Dimensions mmHeight 1, 2, 3, 4, 5Height 0,1,2,3,4,5,6
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.
ConnectionInternal HexInternal Hex
Related accessoriesSilicon caps (Cat#ULCR)- soft, standard, strong;Metal cap(Cat#ULMR);Silicon caps: soft, standard, strong; Metal cap (MM-LFA50)
Company / 510kUNIQA Dental Itd K180598MIS K040807
Primary Predicate
Product NameAngled Anatomic Abutments# UAAREsthetic Angulated Abutment
Dimensions mmHeight 1,2,3,4 - Angle 15Height 1,2,3,4 - Angle 25Height 1,2,3 - Angle 15Height 1,2,3 - Angle 25
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.
ConnectionInternal HexInternal Hex
Company / 510kUNIQA Dental Itd #UABRMIS K040807
Primary Predicate
Product NameAngled AbutmentAngulated Cement Abutment
Dimensions mmLength 9,12 - Angle 15, 25Length 9,11 - Angle 15, 25
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.
ConnectionInternal HexInternal Hex

{17}------------------------------------------------

Company / 510kUNIQA Dental Itd K180598MIS K040807Nobel Biocare K072570
Primary PredicateReference device
Product NameAngled Multi Unit Abutment, MUA, D-type#UAMDEsthetic Angulated AbutmentMulti-Unit Abutment
Indication for UseUNIQA Dental ® Dental Implants System isindicated for use in surgical and restorativeapplications for placement in the bone of theupper or lower jaw to provide support forprosthetic devices, such as artificial teeth, inorder to restore the patient's chewingfunction. UNIQA Dental ® Dental ImplantsSystem is indicated also for immediateloading when good primary stability isachieved and with appropriate occlusalloading.UNIQA Conical Connection Implants: #UCI &#UC7 are to be used only with straightabutments.Conical Mini implants (Ø3.3mm) areindicated for use in surgical and restorativeapplications for placement only in themandibular central, lateral incisor andmaxillary lateral incisor regions of partiallyedentulous jaws, to provide support forThe MIS Dental Implant System isintended to be surgically placed inthe bone of the upper or lower jawarches to provide support forprosthetic devices, such as artificialteeth, in order to restoremasticatory function.NobelActive Multi UnitAbutment is a pre-manufacturedprosthetic component directlyconnected to the endosseousdental implant and is intendedfor use as an aid in prostheticrehabilitation.

{18}------------------------------------------------

Image /page/18/Picture/0 description: The image shows the logo for UNIQA Dental. The word "UNIQA" is in large, green, sans-serif font, with a small, dark red square above the "I". Below "UNIQA" is the word "DENTAL", also in green, sans-serif font, but smaller than "UNIQA". The logo is simple and modern.

prosthetic devices such as artificial teeth, inorder to restore the patient chewing function.Mandibular central and lateral incisors mustbe splinted if using two or more narrowimplants adjacent to one another.
DimensionsHeight 1,2,3 - Angle 17Height 1,2,3 - Angle 30Height 1,2,3 - Angle 15Height 1,2,3 - Angle 25Height 1.5, 2.5, 3.5, 4.5Angles 17, 30
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.
ConnectionInternal HexInternal HexInternal Hex/Conical
Related ComponentsSleeve for Multi Unit Abutment, MUA,Temporary, D-type#USTDSleeve for Multi Unit Abutment, MUA,Temporary, V-type#USTV+ screw (#UMSD)Sleeve=Temporary copying(29046) + screw, plastic cap,MU screw#29285Related tools are applicable
Company / 510kUNIQA Dental Itd K180598MIS K040807MIS K163349
Primary PredicateReference device
Product NameStraight Multi Unit Abutment, MUA,D-type # USMDAnatomic transgingivalAbutmentStraight Multi Unit Abutments
Indication for UseUNIQA Dental ® Dental ImplantsSystem is indicated for use in surgicaland restorative applications forplacement in the bone of the upper orlower jaw to provide support forprosthetic devices, such as artificialteeth, in order to restore the patient'schewing function. UNIQA Dental ®Dental Implants System is indicatedalso for immediate loading whengood primary stability is achieved andwith appropriate occlusal loading.UNIQA Conical Connection Implants:#UCI & #UC7 are to be used onlywith straight abutments.Conical Mini implants (Ø3.3mm) areThe MIS Dental Implant System isintended to be surgically placed inthe bone of the upper or lower jawarches to provide support forprosthetic devices, such as artificialteeth, in order to restore masticatoryfunction.MIS V3 Conical Connection DentalImplant System is intended to besurgically placed in the bone of theupper or lower jaw arches to providesupport for prosthetic devices, suchas artificial teeth, in order to restoremasticatory function. When a one-stage surgical procedure is applied,the implant may be immediatelyloaded when good primary stability isachieved and the occlusal load isappropriate. Narrow implants(Ø3.3mm) are indicated for use insurgical and restorative applicationsfor placement only in the mandibularcentral, lateral incisor and maxillary
indicated for use in surgical andrestorative applications for placementonly in the mandibular central, lateralincisor and maxillary lateral incisorregions of partially edentulous jaws,to provide support for prostheticdevices such as artificial teeth, inorder to restore the patient chewingfunction. Mandibular central andlateral incisors must be splinted ifusing two or more narrow implantsadjacent to one another.lateral incisor regions of partiallyedentulous jaws, to provide supportfor prosthetic devices such asartificial teeth, in order to restore thepatient chewing function. Mandibularcentral and lateral incisors must besplinted if using two or more narrowimplants adjacent to one another.
Dimensions mmDiameter: RegularHeights 1,2,3,4Height 1,2,3,4Diameter: RegularHeights 1,2,3,4,5
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.
ConnectionInternal HexInternal HexConical Hex
Related ComponentsSleeve, Healing Cap, plastic capSleeve, Healing Cap, plastic cap
Company / 510kUNIQA Dental Itd K180598MIS K040807Nobel Biocare K072570
Primary PredicateReference device
Product NameSet Angled Multi Unit Abutment,MUA, D-type, Castable Sleeve# UAMCEsthetic Angulated AbutmentMulti-Unit Abutment
Indication for UseUNIQA Dental ® Dental ImplantsSystem is indicated for use in surgicaland restorative applications forplacement in the bone of the upper orlower jaw to provide support forprosthetic devices, such as artificialteeth, in order to restore the patient'schewing function. UNIQA Dental ®Dental Implants System is indicatedalso for immediate loading whengood primary stability is achieved andwith appropriate occlusal loading.UNIQA Conical Connection Implants:#UCI & #UC7 are to be used onlyThe MIS Dental Implant System isintended to be surgically placed inthe bone of the upper or lower jawarches to provide support forprosthetic devices, such as artificialteeth, in order to restore masticatoryfunction.NobelActive Multi Unit Abutment is apre-manufactured prostheticcomponent directly connected to theendosseous dental implant and isintended for use as an aid inprosthetic rehabilitation.
Dimensions mmDiameter: RegularHeight 1,2,3 - Angle 17Height 1,2,3 - Angle 30Height 1,2,3 - Angle 15Height 1,2,3 - Angle 25Height 1.5, 2.5, 3.5, 4.5Angles 17, 30
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.
ConnectionInternal HexInternal HexInternal Hex/Conical
Related ComponentsThe set is available with a Plastic sleeve + Sleeve screw + instrument + Multi unit screw (#UMSD)Sleeve=Temporary copying (29046) + screw, plastic cap, MU screw#29285Related tools are applicable
Company / 510kUNIQA Dental Itd K180598MIS K040807Nobel Biocare K072570
Product NameSet Angled Multi Unit Abutment, MUA, D-type, Temporary Sleeve # UAMTEsthetic Angulated AbutmentReference deviceMulti-Unit Abutment
Dimensions mmDiameter: RegularHeight 1,2,3 - Angle 17Height 1,2,3 - Angle 30Height 1,2,3 - Angle 15Height 1,2,3 - Angle 25Height 1.5, 2.5, 3.5, 4.5Angles 17, 30
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.
ConnectionInternal HexInternal HexInternal Hex/Conical
Related ComponentsThe set is available with a Transfer sleeve + Sleeve screw + instrument + Multi unit screw (#UMSD)Sleeve=Temporary copying (29046) + screw, plastic cap, MU screw#29285
Related tools are applicable
Company / 510kUNIQA Dental Itd K180598MIS K040807Nobel Biocare K072570
Primary PredicateReference device
Product NameHealing cap for MUA, D-type #UMHDHealing CapsMulti-Unit Abutment / Healing cap#31145
Indication for UseUNIQA Dental ® Dental Implants System is indicated for use in surgical and restorative applications for placement in the bone of the upper or lower jaw to provide support for prosthetic devices, such as artificial teeth, in order to restore the patient's chewing function. UNIQA Dental ® Dental Implants System is indicated also for immediate loading when good primary stability is achieved and with appropriate occlusal loading. UNIQA Conical Connection Implants: #UCI & #UC7 are to be used only with straight abutments. Conical Mini implants (Ø3.3mm) are indicated for use in surgical and restorative applications for placement only in the mandibular central, lateral incisor and maxillary lateral incisor regions of partially edentulous jaws, to provide support for prosthetic devices such as artificial teeth, in order to restore the patient chewing function. Mandibular central and lateral incisors must be splinted if using two or more narrow implants adjacent to one another.The MIS Dental Implant System is intended to be surgically placed in the bone of the upper or lower jaw arches to provide support for prosthetic devices, such as artificial teeth, in order to restore masticatory function.NobelActive Multi Unit Abutment is a pre-manufactured prosthetic component directly connected to the endosseous dental implant and is intended for use as an aid in prosthetic rehabilitation.
Dimensions mmHeight 4.0Wide -Diameter. 5.0, 6.5; Height 3,4,5,6Narrow -Diameter 3.3, 4.3 - Height 2, 3, 4, 6,8Heights 4.1, 5.5
Standard -Diameter 4.0, 4.8, 5.5; Height2,3,4,5,6
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.
ConnectionInternal HexInternal HexInternal Hex

{19}------------------------------------------------

Image /page/19/Picture/0 description: The image shows the logo for UNIQA Dental. The word "UNIQA" is in large, green, sans-serif font, with a small, dark red square above the "i". Below "UNIQA" is the word "DENTAL", also in green, sans-serif font, but smaller than "UNIQA". The logo is simple and clean, with a focus on the company name.

{20}------------------------------------------------

Image /page/20/Picture/0 description: The image shows the logo for UNIQA Dental. The word "UNIQA" is in large, green, sans-serif font, with a small, dark red square above the "I". Below "UNIQA" is the word "DENTAL" in a smaller, green, sans-serif font. The logo is simple and clean, with a focus on the company name.

{21}------------------------------------------------

{22}------------------------------------------------

Company / 510kUNIQA Dental Itd K180598MIS K040807
Primary Predicate
Product NameBall Attachment #UBARBall Attachment
Indication for UseUNIQA Dental ® Dental Implants System isindicated for use in surgical and restorativeapplications for placement in the bone of the upperor lower jaw to provide support for prostheticdevices, such as artificial teeth, in order to restorethe patient's chewing function. UNIQA Dental ®Dental Implants System is indicated also forimmediate loading when good primary stability isachieved and with appropriate occlusal loading.UNIQA Conical Connection Implants: #UCI & #UC7are to be used only with straight abutments.Conical Mini implants (Ø3.3mm) are indicated foruse in surgical and restorative applications forplacement only in the mandibular central, lateralincisor and maxillary lateral incisor regions ofpartially edentulous jaws, to provide support forprosthetic devices such as artificial teeth, in order torestore the patient chewing function. Mandibularcentral and lateral incisors must be splinted if usingtwo or more narrow implants adjacent to oneanother.The MIS Dental Implant System is intended to besurgically placed in the bone of the upper or lowerjaw arches to provide support for prostheticdevices, such as artificial teeth, in order to restoremasticatory function.
Dimensions mmHeight 0.5,1,2,3,4,5,6, 7Height 1,2,3,4,5
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.
ConnectionInternal HexInternal Hex
Related ComponentsMetal Caps(#UBMR-0001), Silicon Caps(#UBSR-0001)Metal Caps, Silicon Caps
Company / 510kUNIQA Dental Itd K180598MIS K040807
Primary Predicate
Product NameHealing Caps #UHXXHealing Caps
Indication for UseUNIQA Dental ® Dental Implants System isThe MIS Dental Implant System is intended to be
indicated for use in surgical and restorativesurgically placed in the bone of the upper or lower
applications for placement in the bone of the upperjaw arches to provide support for prosthetic
or lower jaw to provide support for prostheticdevices, such as artificial teeth, in order to restore
devices, such as artificial teeth, in order to restoremasticatory function.
the patient's chewing function. UNIQA Dental ®
Dental Implants System is indicated also for
immediate loading when good primary stability is
achieved and with appropriate occlusal loading.
UNIQA Conical Connection Implants: #UCI & #UC7
are to be used only with straight abutments.
Conical Mini implants (Ø3.3mm) are indicated for
use in surgical and restorative applications for
placement only in the mandibular central, lateral
incisor and maxillary lateral incisor regions of
partially edentulous jaws, to provide support for
prosthetic devices such as artificial teeth, in order to
restore the patient chewing function. Mandibular
central and lateral incisors must be splinted if using
two or more narrow implants adjacent to one
another.
Dimensions mmWide (# UHCW) -Wide -
Diameter 5.5, 6.3 Height 2,3,4,5,6,7Diameter. 5.0, 6.5; Height 3,4,5,6
Narrow (# UHCN) -Diameter 3.5; Height 3, 5,7Narrow -Diameter 3.3, 4.3 - Height 2, 3, 4, 6,8
Regular (#UHCR) -Standard -
Diameter 4.6, Height 2,3,4,5,6,7Diameter 4.0, 4.8, 5.5; Height 2,3,4,5,6
MaterialTitanium alloy Ti-6AI-4V-ELI.Titanium alloy Ti-6AI-4V-ELI.
ConnectionInternal HexInternal Hex
Company / 510kUNIQA Dental Itd K180598MIS K040807
Primary Predicate

{23}------------------------------------------------

{24}------------------------------------------------

Product Name# USARStraight Anatomic AbutmentAnatomic transgingivalAbutment
Dimensions mmHeight 1,2,3,4Height 1,2,3,4
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.
ConnectionInternal HexInternal Hex
Company / 510kUNIQA Dental Itd K180598MIS K040807A.B.Dental Devices Ltd K112440
Primary PredicateReference device
Product NameStraight Abutment #USBXCemented AbutmentP3 Abutment Anti rotation
Indication for UseUNIQA Dental® Dental Implants Systemis indicated for use in surgical andrestorative applications for placement inthe bone of the upper or lower jaw toprovide support for prosthetic devices,such as artificial teeth, in order to restorethe patient's chewing function. UNIQADental® Dental Implants System isindicated also for immediate loading whengood primary stability is achieved and withappropriate occlusal loading.UNIQA Conical Connection Implants: #UCI& #UC7 are to be used only with straightabutments.Conical Mini implants (Ø3.3mm) areindicated for use in surgical and restorativeapplications for placement only in themandibular central, lateral incisor andmaxillary lateral incisor regions of partiallyedentulous jaws, to provide support forprosthetic devices such as artificial teeth,in order to restore the patient chewingfunction. Mandibular central and lateralincisors must be splinted if using two ormore narrow implants adjacent to oneanother.The MIS Dental Implant System isintended to be surgically placed inthe bone of the upper or lower jawarches to provide support forprosthetic devices, such asartificial teeth, in order to restoremasticatory function.The AB Dental Devices implants areintended for surgical placement in themaxillary and/or mandibular arch tosupport crowns, bridges, oroverdentures in edentulous or partiallyedentulous patients. 17 Integraimplant, 15 Conical implant, P15Temporary abutment, P12-T,LTemporary flat connection abutment,and P16 Straight adaptor areappropriate for immediate loadingwhen good primary stability is achievedand with appropriate occlusal loading.
Dimensions mmDiameter : Regular (#USBR)Diameter : Regular, WideDiameter : 3.0, 3.75, 5

{25}------------------------------------------------

Length 5, 7, 9, 11, 13, 15 mmDiameter : Wide (# USBW)Length 5, 7, 9, 12 mm (=Heights1,2,3,4)Length 5, 7, 9, 11, 12, 15
Length 5, 7, 9, 11, 13, 15 mm
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.
ConnectionInternal HexInternal HexInternal Hex
Company / 510kUNIQA Dental Itd K180598MIS K040807
Primary Predicate
Product NameStraight Abutment with shoulder #USSXCemented Abutment
Indication for UseUNIQA Dental ® Dental ImplantsSystem isindicated for use in surgical and restorativeapplications for placement in the bone of the upperor lower jaw to provide support for prostheticdevices, such as artificial teeth, in order to restorethe patient's chewing function. UNIQA Dental ®Dental Implants System is indicated also forimmediate loading when good primary stability isachieved and with appropriate occlusal loading.UNIQA Conical Connection Implants: #UCI & #UC7are to be used only with straight abutments.Conical Mini implants (Ø3.3mm) are indicated foruse in surgical and restorative applications forplacement only in the mandibular central, lateralincisor and maxillary lateral incisor regions ofpartially edentulous jaws, to provide support forprosthetic devices such as artificial teeth, in order torestore the patient chewing function. Mandibularcentral and lateral incisors must be splinted if usingtwo or more narrow implants adjacent to oneanother.The MIS Dental Implant System is intended to besurgically placed in the bone of the upper or lowerjaw arches to provide support for prostheticdevices, such as artificial teeth, in order to restoremasticatory function.
Dimensions mmDiameter :Heights 1,2,3,4Diameter : Regular, WideHeights 1,2,3,4
MaterialTitanium alloy Ti-6AI-4V-ELI.Titanium alloy Ti-6AI-4V-ELI.
ConnectionInternal HexInternal Hex
Company / 510kUNIQA Dental Itd K180598MIS K040807
Primary Predicate
Snap on transfer #UTSRCemented Abutment
Indication for UseUNIQA Dental ® Dental Implants System isindicated for use in surgical and restorativeapplications for placement in the bone of the upperor lower jaw to provide support for prostheticdevices, such as artificial teeth, in order to restorethe patient's chewing function. UNIQA Dental ®Dental Implants System is indicated also forimmediate loading when good primary stability isachieved and with appropriate occlusal loading.UNIQA Conical Connection Implants: #UCI & #UC7are to be used only with straight abutments.Conical Mini implants (Ø3.3mm) are indicated foruse in surgical and restorative applications forplacement only in the mandibular central, lateralincisor and maxillary lateral incisor regions ofpartially edentulous jaws, to provide support forprosthetic devices such as artificial teeth, in order torestore the patient chewing function. Mandibularcentral and lateral incisors must be splinted if usingtwo or more narrow implants adjacent to oneanother.The MIS Dental Implant System is intended to besurgically placed in the bone of the upper or lowerjaw arches to provide support for prostheticdevices, such as artificial teeth, in order to restoremasticatory function.
Diameter: Regular,Heights 1,2,3,4,5Diameter : Regular, Slim, WideHeights 1,2,3,4
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI. or gold
ConnectionInternal HexInternal Hex
Company / 510kUNIQA Dental Itd K180598MIS K040807
Primary Predicate
Product NameScrew for Abutment #USXXTi Base
Dimensions mmMeasurements:Length 8.3 mm #USWRLength 8.1 mm #USWLDiameter: Narrow, Regular, wideLength 8.1 mm
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.
Company / 510kUNIQA Dental Itd K180598MIS K040807MIS K163349
Primary PredicateReference device
Product NameStraight Multi Unit Abutment, MUA,Esthetic Angulated AbutmentStraight Multi Unit Abutments
V-type# USMV
Indication for UseUNIQA Dental ® Dental ImplantsSystem is indicated for use in surgicaland restorative applications forplacement in the bone of the upper orlower jaw to provide support forprosthetic devices, such as artificialteeth, in order to restore the patient'schewing function. UNIQA Dental ®Dental Implants System is indicatedalso for immediate loading whengood primary stability is achieved andwith appropriate occlusal loading.UNIQA Conical Connection Implants:#UCI & #UC7 are to be used onlywith straight abutments.Conical Mini implants (Ø3.3mm) areindicated for use in surgical andrestorative applications for placementonly in the mandibular central, lateralincisor and maxillary lateral incisorregions of partially edentulous jaws,to provide support for prostheticdevices such as artificial teeth, inorder to restore the patient chewingfunction. Mandibular central andlateral incisors must be splinted ifThe MIS Dental Implant System isintended to be surgically placed inthe bone of the upper or lower jawarches to provide support forprosthetic devices, such as artificialteeth, in order to restore masticatoryfunction.MIS V3 Conical Connection DentalImplant System is intended to besurgically placed in the bone of theupper or lower jaw arches to providesupport for prosthetic devices, suchas artificial teeth, in order to restoremasticatory function. When a one-stage surgical procedure is applied,the implant may be immediatelyloaded when good primary stability isachieved and the occlusal load isappropriate. Narrow implants(Ø3.3mm) are indicated for use insurgical and restorative applicationsfor placement only in the mandibularcentral, lateral incisor and maxillarylateral incisor regions of partiallyedentulous jaws, to provide support forprosthetic devices such as artificial teeth, in order to restore thepatient chewing function. Mandibularcentral and lateral incisors must besplinted if using two or more narrowimplants adjacent to one another.
using two or more narrow implants
adjacent to one another.
Dimensions mmDiameter: RegularHeight 1,2,3 - Angle 15Diameter: Regular
Heights 1,2,3,4Height 1,2,3 - Angle 25Heights 1,2,3,4,5
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.
ConnectionInternal HexInternal HexConical Hex
Related components(L=length)Screw for Multi Unit Abutmentsleeve, V-type (#UMSV-0002) -measurement 3.9 L mm ;Healing cap for Multi Unit Abutment,MUA, V-type (#UMHV-0004) - 3.1 LmmMulti unit screw measurement 3.8 Lmm;Healing Cap measurement 4.3 L mm
Company / 510kUNIQA Dental Itd K180598MIS K040807Primary PredicateMIS K163349Reference device
Product NameHealing Cap # UOHXHealing CapsHealing Cap
Dimensions mmDiameter: Mini (#UOHM) - Diameter4.0, 4.5 Heights 3, 4, 5,7Regular (#UOHR) -Diameter 4.0, 4.5, 5.0, 6.0, 7.0Heights 3, 4, 5, 7Wide -Diameter. 5.0, 6.5; Height 3,4,5,6Narrow -Diameter 3.3, 4.3 - Height 2, 3, 4, 6,8Standard -Diameter 4.0, 4.8, 5.5; Height2,3,4,5,6Diameter: SlimDiameter 3.3, 4.0, 4.8, Heights3,4,5,6,8Regular, Diameter 3.9, 4.3, 5.0,Heights 3,4,5,6,8
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.
ConnectionConical HexInternal HexConical Hex
Company / 510kUNIQA Dental Itd K180598MIS K040807Primary PredicateMIS K163349Reference device
Product NameTransfer Abutment #UOTXCemented AbutmentCementing Abutment
Dimensions mmMini Diameter: 4.5 mm, Height 1, 2,3, 4, 5 mm Lengths: 5.5, 7 mm(#UOTM)Regular Diameter: 4.5, 5.0, 6.0 mm,Height 1, 2, 3, 4, 5 mm, Lengths:4.0(not for 4.5), 5.5, 7 mm(#UOTR)Provided with:Screw Mini Conical (#UOSM-0001)Screw Regular Conical (#UOSR-0001Diameter : Regular, WideHeights 1,2,3,4Narrow Diameter: 4.0 Length 1, 3Narrow Diameter: 4.8 Length 1,2, 3Standard Diameter: 4.8 Length1,2,3,4 Height 4,6,8.Provided with:Screw MN-S0160 (mini)MD-S0200, MD-S0222 (standard)
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.
ConnectionConical HexInternal HexConical Hex
Company / 510kUNIQA Dental Itd K180598MIS K040807MIS K163349
Primary PredicateReference device
Product NameStraight Multi Unit Abutment, MUA,C-type (#UOMX)Anatomic transgingivalAbutmentMulti Unit
Indication for UseUNIQA Dental ® Dental ImplantsSystem is indicated for use in surgicaland restorative applications forplacement in the bone of the upper orlower jaw to provide support forprosthetic devices, such as artificialteeth, in order to restore the patient'schewing function. UNIQA Dental ®Dental Implants System is indicatedalso for immediate loading whengood primary stability is achieved andwith appropriate occlusal loading.UNIQA Conical Connection Implants:#UCI & #UC7 are to be used onlywith straight abutments.Conical Mini implants (Ø3.3mm) areindicated for use in surgical andrestorative applications for placementonly in the mandibular central, lateralincisor and maxillary lateral incisorregions of partially edentulous jaws,to provide support for prostheticdevices such as artificial teeth, inorder to restore the patient chewingfunction. Mandibular central andlateral incisors must be splinted ifusing two or more narrow implantsadjacent to one another.The MIS Dental Implant System isintended to be surgically placed inthe bone of the upper or lower jawarches to provide support forprosthetic devices, such as artificialteeth, in order to restore masticatoryfunction.MIS V3 Conical Connection DentalImplant System is intended to besurgically placed in the bone of theupper or lower jaw arches to providesupport for prosthetic devices, suchas artificial teeth, in order to restoremasticatory function. When a one-stage surgical procedure is applied,the implant may be immediatelyloaded when good primary stability isachieved and the occlusal load isappropriate. Narrow implants(Ø3.3mm) are indicated for use insurgical and restorative applicationsfor placement only in the mandibularcentral, lateral incisor and maxillarylateral incisor regions of partiallyedentulous jaws, to provide supportfor prosthetic devices such asartificial teeth, in order to restore thepatient chewing function. Mandibularcentral and lateral incisors must besplinted if using two or more narrowimplants adjacent to one another.
Dimensions mmMini Diameter: 4.0 Height 1, 2,3,4(#UOMM)Height 1,2,3,4Narrow Diameter: Heights 1,2,3,5Standard Diameter: Heights 1,2,3,4
Regular Diameter: 4.0, 5.0, 6.0Height 1, 2,3,4,5 (5mm not for 4Ø)(#UOMR)5(also available Angulated 17, 30 withheight 1,2)
MaterialTitanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.Titanium alloy Ti-6Al-4V-ELI.
ConnectionConical HexInternal HexConical Hex
Related ComponentsSleeve for Multi Unit Abutment, MUA,Rotation, C-type (#USTC-Rx)Diameter Regular : 4.0, 5.0, 6.0Length: 7.Sleeve for Multi Unit Abutment, MUA,Fixed, C-type (#USTC-Fx) DiameterRegular : 4.0, 5.0, 6.0 Length: 7.Screw for MUA sleeve, C-type(#UMSC-0002)Temporary cylinder (#MU-TO480)Screw (#MU-S0220)

{26}------------------------------------------------

{27}------------------------------------------------

ConnectionInternal HexInternal Hex

{28}------------------------------------------------

{29}------------------------------------------------

{30}------------------------------------------------

Image /page/30/Picture/0 description: The image shows the logo for UNIQA Dental. The word "UNIQA" is in large, green, sans-serif font, with a small, dark red square above the "Q". Below "UNIQA", the word "DENTAL" is in a smaller, green, sans-serif font. The overall design is clean and modern.

{31}------------------------------------------------

14 Summary of Equivalence:

UNIQA® Dental Implants System share the same indication for use with its Primary Predicate MIS SEVEN Implant K040807; with two differences UNIQA Conical Implants (#UCI and #UC7) are to be used only with straight abutments, and that the Conical Mini implants (Ø3.3mm) indications are similar to the Reference Device MIS V3 Conical Connection Dental Implant System K163349 the Narrow Implants. The differences do not raise different safety or effectiveness issues as verified by Fatigue testing per ISO 14801:2007.

UNIQA® Dental Implants System, line of Conical Connection Implants (#UCI and #UC7) share similarity with its Reference Device MIS V3 Conical Connection Dental Implant System K163349 and its Reference Device Astra Tech OsseoSpeed TX K101732 in terms of intended use, technological characteristics, conical connection, sterilization method, surgical procedure. The differences are as follow: UNIQA Conical Implants are available in two options of surface treatment (1) SBA - Sand Blast with acid etched in similar to its Reference Device MIS K163349; and (2) Pure & Porous, P&P which is similar to its Reference Device A.B.DENTAL DEVICES LTD K132125; UNIQA line of Conical Hex Implants 3.30 are also provided with 8 mm length, whereas with its Reference Device MIS K163349 3.3Ø implants are provided only from 10 mm length. However, UNIQA share similar implant measurement 3.3Øx8 mm length with its other Reference Device DENTIN K120530; UNIQA conical connection cone angulation is 22° whereas with its Reference Device MIS K163349 introduces 12°, and its other Reference Device OsseoSpeed TX K101732 introduces 21º; The cone angulation is very similar to the OsseoSpeed TX K101732 with a minor difference; UNIQA conical connection implants currently are not distributed with angled abutments thus raise no new and/or different risks. UNIQA implant diameter range is slightly different (3.3, 3.75, 4.2, 5.0) but still is within the range of the Reference Device (3.3, 4.9, 4.3, 5.0); The differences do not raise different safety or effectiveness issues as verified by Fatigue testing per ISO 14801:2007.

UNIQA® Dental Implants System, line of Conical Implant Internal Hex (#USI and #US7) share similarity with its Primary Predicate MIS SEVEN Implant K040807 in terms of intended use, technological characteristics, conical body design, internal hex connection, sterilization method, surgical procedure. The differences are as follow: UNIQA Conical

{32}------------------------------------------------

Implants Internal Hex are available in two options of surface treatment (1) SBA - Sand Blast with acid etched in similar to its Primary Predicate MIS K040807; and (2) Pure & Porous, P&P which is similar to its Reference Device A.B.DENTAL DEVICES LTD K132125; UNIQA line of Conical Implant Internal Hex is available in 3.3Ø, whereas with its Primary Predicate MIS K040807 is available from 3.5Ø. However, this difference doesn't raise any new risk since the same measurements are exist in the Reference Device K120530;

  • 15 Performance Testing:
    Clinical Testing - No clinical data is included in this submission.

Sterilization Validation Test was carried out with accordance to ISO 11137 in order to ensure safety and effectiveness related to UNIQA® Dental Implants - Test results have demonstrated that the SAL of 10-® was achieved and all testing requirements were met. Shelf Life Test was carried out with accordance to ASTM F-1980 in order to validate the claimed shelf life of 5 years.

Steam Sterilization Test was carried out with accordance to ISO 17665 in order to ensure safety and effectiveness related to UNIQA® Dental Abutments - Test results have demonstrated that the SAL of 10-6 was achieved and all testing requirements were met.

Biocompatibility - UNIQA Dental Implants are made of Ti6AI4V ELI using the conventional manufacturing process. Cytotoxicity testing was carried out with accordance to ISO 10993-5 in order to demonstrate that the manufacturing process did not change the biocompatibility profile. No additional biocompatibility testing was deemed necessary since the devices are constructed from medical quality raw material which conforms the international standard ASTM F-136 Eli used for human implant applications.

Fatigue test was carried out with accordance to ISO 14801 in order to verify the mechanical connection strength of implant/abutment, results have demonstrated the performance with the use of UNIQA® Dental Implants / Abutments.

Surface Test was carried out to ensure the cleanness of the implant surface, surface results were met UNIQA requirements.

Risk Assessment was carried out with accordance to ISO 14971 and has demonstrated no new safety and/or effectiveness issues.

{33}------------------------------------------------

16 Conclusion:

As verified by substantial equivalence, risk assessment and bench testing UNIQA® Dental Implants System shares similarity to its predicated devices in terms of intended use, indication for use, raw material, technological characteristics and performance. Therefore, UNIQA® Dental Implants system is considered to be substantially equivalent to its predicate devices.

§ 872.3640 Endosseous dental implant.

(a)
Identification. An endosseous dental implant is a prescription device made of a material such as titanium or titanium alloy that is intended to be surgically placed in the bone of the upper or lower jaw arches to provide support for prosthetic devices, such as artificial teeth, in order to restore a patient's chewing function.(b)
Classification. (1) Class II (special controls). The device is classified as class II if it is a root-form endosseous dental implant. The root-form endosseous dental implant is characterized by four geometrically distinct types: Basket, screw, solid cylinder, and hollow cylinder. The guidance document entitled “Class II Special Controls Guidance Document: Root-Form Endosseous Dental Implants and Endosseous Dental Implant Abutments” will serve as the special control. (See § 872.1(e) for the availability of this guidance document.)(2)
Classification. Class II (special controls). The device is classified as class II if it is a blade-form endosseous dental implant. The special controls for this device are:(i) The design characteristics of the device must ensure that the geometry and material composition are consistent with the intended use;
(ii) Mechanical performance (fatigue) testing under simulated physiological conditions to demonstrate maximum load (endurance limit) when the device is subjected to compressive and shear loads;
(iii) Corrosion testing under simulated physiological conditions to demonstrate corrosion potential of each metal or alloy, couple potential for an assembled dissimilar metal implant system, and corrosion rate for an assembled dissimilar metal implant system;
(iv) The device must be demonstrated to be biocompatible;
(v) Sterility testing must demonstrate the sterility of the device;
(vi) Performance testing to evaluate the compatibility of the device in a magnetic resonance (MR) environment;
(vii) Labeling must include a clear description of the technological features, how the device should be used in patients, detailed surgical protocol and restoration procedures, relevant precautions and warnings based on the clinical use of the device, and qualifications and training requirements for device users including technicians and clinicians;
(viii) Patient labeling must contain a description of how the device works, how the device is placed, how the patient needs to care for the implant, possible adverse events and how to report any complications; and
(ix) Documented clinical experience must demonstrate safe and effective use and capture any adverse events observed during clinical use.