K Number
K120080
Manufacturer
Date Cleared
2012-05-25

(135 days)

Product Code
Regulation Number
878.4810
Reference & Predicate Devices
Predicate For
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

The SHASER HRS2 Hair Removal System is an over-the-counter device intended for removal of unwanted hair. It is also intended for permanent reduction in unwanted hair. Permanent hair reduction is defined as the long-term stable reduction in the number of hairs re-growing when measured at 6, 9, and12 months after the completion of a treatment regimen.

Device Description

The SHASER HRS2 Hair Removal System is a personal, light-based, hair reduction system intended to be sold over-the-counter directly to the end user. The device provides permanent hair reduction as defined below using Intense Pulsed Light (IPL) technology.

The SHASER HRS2 Hair Removal System consists of a powered base unit and a tethered hand piece from which the IPL flashes are delivered to the patient's skin. The system will be sold with light carring a cloth, and user's manual.

AI/ML Overview

Here's a breakdown of the acceptance criteria and the study details for the SHASER HRS2 Hair Removal System, based on the provided 510(k) summary:

1. Acceptance Criteria and Reported Device Performance

Acceptance Criteria (Definition of Permanent Hair Reduction)Reported Device Performance (Average Hair Reduction)
Long-term stable reduction in the number of hairs regrowing when measured at 6, 9, and 12 months after the completion of a treatment regimen.At 3 months: 37% average hair reduction
At 6 months: 48% average hair reduction
At 12 months: 66% average hair reduction

Note: The acceptance criteria itself is qualitative ("long-term stable reduction"). The clinical trial aims to demonstrate that the device achieves this by reporting quantitative hair reduction percentages at specified time points.

2. Sample Size Used for the Test Set and Data Provenance

  • Sample Size: Not explicitly stated as a single number, but the study was conducted on "a population of approximately 50% female and 50% male subjects from diverse demographic sub-groups." The specific number of subjects is not provided, but it implies a cohort designed to represent a diverse user base.
  • Data Provenance: The document does not specify the country of origin of the data. It indicates a "clinical trial was conducted," suggesting prospective data collection.

3. Number of Experts Used to Establish the Ground Truth for the Test Set and Qualifications of Those Experts

This information is not provided in the given document. The summary focuses on hair count measurements without detailing expert involvement in establishing ground truth for the hair counts.

4. Adjudication Method for the Test Set

This information is not provided in the given document.

5. If a Multi Reader Multi Case (MRMC) Comparative Effectiveness Study was done

No, an MRMC comparative effectiveness study was not done. This type of study typically involves comparing human readers' performance with and without AI assistance, which is not applicable to this hair removal device.

6. If a Standalone (i.e. algorithm only without human-in-the loop performance) was done

This concept is not applicable to the SHASER HRS2 Hair Removal System. This device is a physical, light-based hair removal system, not an algorithm or AI system that would have a standalone performance measured independently of a human user. The "performance" here refers to the physical outcome of hair reduction on human subjects.

7. The type of ground truth used

The ground truth used was hair counts. These were "taken before treatment and 3, 6, and 12 months following the final treatment." This is a direct, objective measurement for assessing hair reduction.

8. The sample size for the training set

This information is not applicable as this device is a physical light-based hair removal system, not an AI/ML algorithm that would undergo training on a dataset.

9. How the ground truth for the training set was established

This information is not applicable for the reasons stated above.

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K120080

510(k) Summary of Safety and Effectiveness

This summary of 510(k) safety and effectiveness information is being submitted in accordance with the requirements of SMDA 1990 and 21 CFR 807.92,

Submitter Name:SHASER Inc.
Submitter Address :130 New Boston St., Ste 201, Woburn, MA 01801
Contact Person:Daniel L. Roth
Phone Number:(781)995-2246
Fax Number:(781)933-4640
Date Prepared:December, 2011
Device Trade Name:Shaser HRS2 Hair Removal System
Device Common Name:Light-based Hair Removal System
Classification Name:Laser surgical instrument for use in general and plasticsurgery and in dermatology, product code ONF
Predicate devices:Shaser IPL Hair Removal System, K103560Home Skinovations Silk'n Flash N Go K103184
Reason for submission:Expanded use indication

Reason for submission:

Device Description:

The SHASER HRS2 Hair Removal System is a personal, light-based, hair reduction system intended to be sold over-the-counter directly to the end user. The device provides permanent hair reduction as defined below using Intense Pulsed Light (IPL) technology.

The SHASER HRS2 Hair Removal System consists of a powered base unit and a tethered hand piece from which the IPL flashes are delivered to the patient's skin. The system will be sold with light carring a cloth, and user's manual.

Intended Use:

The SHASER HRS2 Hair Removal System is an over-the-counter device intended for removal of unwanted hair. It is also intended for permanent reduction in unwanted hair. Permanent hair reduction is defined as the long-term stable reduction in the number of hairs re-growing when measured at 6, 9, and12 months after the completion of a treatment regimen.

Performance Data

The device complies with the following U.S. Food and Drug Administration performance standards: 21 CFR § 1040.10 & 1040.11. A clinical.trial was conducted to demonstrate the safety and effectiveness of the SHASER HRS2 Hair Removal System for over the counter use for permanent reduction in hair regrowth defined as a long-term, stable reduction in hair counts following a treatment regime. In a clinical trial, test sites including arm, leg, chest, abdomen, bikini line and underarms were treated 3 times at 2 week intervals on a population of approximately 50% female and 50% male subjects from diverse demographic sub-groups. Hair counts were taken before treatment and 3, 6, and 12 months following the final treatment. The results showed an average reduction of 37%. 48%, and 66% at each respective end point.

Substantial Equivalence

Technological Characteristics and Comparison to Predicate Device(s);

The SHASER HRS2 Hair Removal System is substantially equivalent to the Shaser IPL Hair Removal System K103560 and the Home Skinovations Silk'n Flash N Go K103184

The SHASER HRS2 Hair Removal System has similar intended use and indications, and same technological characteristics, and principles of operation as the predicate devices. Any minor differences between the SHASER HRS2 Hair Removal System and its predicate devices raise no new questions of safety or effectiveness nor change the device's intended therapeutic effect in comparison to its predicates. Performance data demonstrate that SHASER HRS2 Hair Removal System is as safe and effective as its predicate devices for the stated indications. Thus, the SHASER HRS2 Hair Removal System is substantially equivalent.

MAY 2 5 2012

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DEPARTMENT OF HEALTH & HUMAN SERVICES

Image /page/1/Picture/1 description: The image shows the logo for the U.S. Department of Health & Human Services. The logo features a stylized eagle with its wings spread, symbolizing protection and service. The words "DEPARTMENT OF HEALTH & HUMAN SERVICES • USA" are arranged in a circular pattern around the eagle.

Public Health Service

Food and Drug Administration 10903 New Hampshire Avenue Document Control Room -WO66-G609 Silver Spring, MD 20993-0002

MAY 2 5 2012

Shaser, Incorporated % The CRO Group, Incorporated Mr. Glen Emelock Senior Partner 32 Harrison Street Melrose, Massachusetts 02176

Re: K120080

Trade/Device Name: SHASER HRS2 Hair Removal System Regulation Number: 21 CFR 878.4810 Regulation Name: Laser surgical instrument for use in general and plastic surgery and in dermatology Regulatory Class: Class II

Product Code: ONF Dated: March 06, 2012 Received: March 07, 2012

Dear Mr. Glen Emelock:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you; however, that device labeling must be truthful and not misleading.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

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Page 2 – Mr. Glen Emelock

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act

or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807): labeling (21 CFR Part 801): medical device reporting of medical device-related adverse events) (21 CFR 803); good manufacturing practice requirements as set forth in the quality systems (OS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please go to http://www.fda.gov/AboutFDA/CentersOffices/CDRHOffices/ucm115809.htm for the Center for Devices and Radiological Health's (CDRH's) Office of Compliance. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to

http://www.fda.gov/MedicalDevices/Safety/ReportaProblem/default.htm for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance.

You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers. International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 796-7100 or at its Internet address http://www.fda.gov/MedicalDevices/Resourcesfor You/Industry/default.htm.

Sincerely yours.

Sincerely yours,

Mark A. Milliken

Mark N. Melkerson Director Division of Surgical, Orthopedic and Restorative Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure .

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Indications for Use

510(k) Number: K120080

Device Name: SHASER HRS2 Hair Removal System

Indications For Use:

The SHASER HRS2 Hair Removal System is an over-the-counter device intended for removal of unwanted hair. It is also intended for permanent reduction in unwanted hair. Permanent hair reduction is defined as the long-term stable reduction in the number of hairs regrowing when measured at 6, 9, and12 months after the completion of a treatment regimen.

Prescription Use (Part 21 CFR 801 Subpart D)

AND/OR

Over-The-Counter Use × (21 CFR 807 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE.ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

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(Division Sign-Off) Division of Surgical, Orthopedic, and Restorative Devices

510(k) Number K120080

A-2

§ 878.4810 Laser surgical instrument for use in general and plastic surgery and in dermatology.

(a)
Identification. (1) A carbon dioxide laser for use in general surgery and in dermatology is a laser device intended to cut, destroy, or remove tissue by light energy emitted by carbon dioxide.(2) An argon laser for use in dermatology is a laser device intended to destroy or coagulate tissue by light energy emitted by argon.
(b)
Classification. (1) Class II.(2) Class I for special laser gas mixtures used as a lasing medium for this class of lasers. The devices subject to this paragraph (b)(2) are exempt from the premarket notification procedures in subpart E of part 807 of this chapter, subject to the limitations in § 878.9.