K Number
K093051
Device Name
HYLATOPIC PLUS EMOLLIENT FOAM
Date Cleared
2009-12-07

(68 days)

Product Code
Regulation Number
N/A
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
Under the supervision of a healthcare professional, Hylatopic™ Plus Emollient Foam, an aerosol-based emollient foam, is indicated to manage and relieve the burning, itching and pain experienced with various types of dermatoses, including atopic dermatitis, allergic contact dermatitis and radiation dermatitis. Hylatopic™ Plus Emollient Foam also helps to relieve dry, waxy skin by maintaining a moist wound & skin environment, which is beneficial to the healing process. Hylatopic™ Plus Emollient Foam is indicated for use in: - Atopic Dermatitis - Allergic Contact Dermatitis - Radiation Dermatitis
Device Description
Hylatopic™ Plus Emollient Foam is a non-steroidal, non-sterile, off-white, low odor, fragrance free, topical aerosol foam. When Hylatopic™ Plus Emollient Foam is dispensed, foam is formed. The propellant in the foam dissipates very quickly and the foam is then rubbed on the affected skin. The Hylatopic™ Plus Emollient Foam when applied to diseased skin forms a protective barrier that helps to maintain a moist wound and skin environment. This device is presented as a prescription product that requires the physician to diagnosis the disease state and prescribe the product.
More Information

Not Found

No
The device description and intended use clearly describe a topical emollient foam for skin conditions, with no mention of any computational or analytical capabilities that would involve AI or ML.

Yes
The device is indicated to manage and relieve burning, itching, and pain associated with various dermatoses, and helps maintain a moist environment beneficial to healing, which qualifies it as a therapeutic device.

No

The device description indicates it is an emollient foam used to manage and relieve symptoms of dermatoses, and that a physician diagnoses the disease state. It does not perform any diagnostic function.

No

The device description clearly states it is a topical aerosol foam, which is a physical substance applied to the skin, not software.

Based on the provided information, this device is not an IVD (In Vitro Diagnostic).

Here's why:

  • Intended Use: The intended use is to manage and relieve symptoms of various dermatoses by being applied topically to the skin. This is a therapeutic or symptomatic relief function, not a diagnostic one.
  • Device Description: The device is a topical aerosol foam applied to the skin to form a protective barrier. This is a physical barrier and emollient function, not a test performed on a sample taken from the body to diagnose a condition.
  • Lack of Diagnostic Activity: There is no mention of analyzing samples (blood, urine, tissue, etc.) or providing information for the diagnosis of a disease or condition.

IVD devices are used to examine specimens derived from the human body to provide information for diagnostic purposes. This device is applied to the body for therapeutic and symptomatic relief.

N/A

Intended Use / Indications for Use

Under the supervision of a healthcare professional. Hylatopic™ Plus Emollient Foam, an aerosol-based emollient foam, is indicated to manage and relieve the burning, itching and pain experienced with various types of dermatoses, including atopic dermatitis, allergic contact dermatitis and radiation dermatitis. Hylatopic™ Plus Emollient Foam also helps to relieve dry, waxy skin by maintaining a moist wound & skin environment, which is beneficial to the healing process.

Hylatopic™ Plus Emollient Foam provides a non-steroidal alternative for the management of symptoms associated with various types of dermatoses.

Hylatopic™ Plus Emollient Foam is indicated for use in:

  • Atopic Dermatitis
  • Allergic Contact Dermatitis
  • Radiation Dermatitis

Product codes

MGQ, FRO

Device Description

Hylatopic™ Plus Emollient Foam is a non-steroidal, non-sterile, off-white, low odor, fragrance free, topical aerosol foam. When Hylatopic™ Plus Emollient Foam is dispensed, foam is formed. The propellant in the foam dissipates very quickly and the foam is then rubbed on the affected skin. The Hylatopic™ Plus Emollient Foam when applied to diseased skin forms a protective barrier that helps to maintain a moist wound and skin environment. This device is presented as a prescription product that requires the physician to diagnosis the disease state and prescribe the product.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

Skin

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Healthcare professional

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies (study type, sample size, AUC, MRMC, standalone performance, key results)

Functional and performance testing has been conducted to assess the safety and effectiveness of Hylatopic™ Plus Emollient Foam and all results are satisfactory.

Key Metrics (Sensitivity, Specificity, PPV, NPV, etc.)

Not Found

Predicate Device(s)

K041342, K052643, K083024

Reference Device(s)

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information

Not Found

N/A

0

510 (k) Premarket Notification CONFIDENTIAL

SECTION 2

1

510(K) Summary

2. 510(k) Summary

Image /page/0/Picture/6 description: The image shows the logo for Collegium Pharmaceutical. The logo consists of the letters "CP" on the left, followed by the word "COLLEGIUM" in large, bold letters. Below "COLLEGIUM" is the word "Pharmaceutical" in a smaller font. The logo is simple and professional, and it is likely used to represent the company in its marketing and branding materials.

2.1 510(k) Owner's Name

Collegium Pharmaceutical, Incorporated 400 Highland Corporate Drive Cumberland, RI 02864 Device Establishment Registration Number: 3005150234

2.2 Contact Individual

Ronald M. Gurge, Ph.D. Associate Director, Product Research & Development Collegium Pharmaceutical, Incorporated 401-762-2000, Extension 41 401-762-2043 (fax) rgurge@collegiumpharma.com

2.3 Date Summary Prepared

September 29, 2009

2.4 510(k) Device Name

Proprietary Name: Hylatopic™ Plus Emollient Foam Common/Usual Name: Dressing, Wound & Burn, Hydrogel w/drug and/or biologic Classification Name: Dressing, Wound & Burn, Hydrogel w/drug and/or biologic Panel: General & Plastic Surgery CFR Number: Unclassified Product code: MGQ

400 Highland Corporate Drive · Cumberland, RI · 02864 tel 401 762 2000 fax 401 762 2043

DEC - 7 2009

1

SECTION 2

510(k) SUMMARY (Cont'd)

Devices to Which New Device is Substantially Equivalent 2.5

  • Mimyx® Cream approved under 510(k) K041342, from Stiefel Laboratories, Inc. .
  • Epiceram® Skin Barrier Emulsion approved under 510(k) K052643, from Ceragenix . Corporation.
  • Hylatopic™ Emollient Foam approved under 510(k) K083024, from Collegium . Pharmaceutical. Inc.

2.6 Device Description

Hylatopic™ Plus Emollient Foam is a non-steroidal, non-sterile, off-white, low odor, fragrance free, topical aerosol foam. When Hylatopic™ Plus Emollient Foam is dispensed, foam is formed. The propellant in the foam dissipates very quickly and the foam is then rubbed on the affected skin. The Hylatopic™ Plus Emollient Foam when applied to diseased skin forms a protective barrier that helps to maintain a moist wound and skin environment. This device is presented as a prescription product that requires the physician to diagnosis the disease state and prescribe the product.

2.7 Intended Use of the Device

Under the supervision of a healthcare professional. Hylatopic™ Plus Emollient Foam, an aerosol-based emollient foam, is indicated to manage and relieve the burning, itching and pain experienced with various types of dermatoses, including atopic dermatitis, allergic contact dermatitis and radiation dermatitis. Hylatopic™ Plus Emollient Foam also helps to relieve dry, waxy skin by maintaining a moist wound & skin environment, which is beneficial to the healing process.

Hylatopic™ Plus Emollient Foam provides a non-steroidal alternative for the management of symptoms associated with various types of dermatoses.

2.8 Summary of Technological Characteristics of the Device Compared to the Predicate Devices

All predicate devices referenced are non-sterile, emulsion/cream/foam types that are applied topically to relieve the symptoms of various dermatoses. When Hylatopic™ Plus Emollient Foam is dispensed, foam is formed. The propellant in the foam dissipates very quickly and the foam is then rubbed on the affected skin. The rubbed in product is equivalent to a cream.

2

SECTION 2

510(k) SUMMARY (Cont'd)

��

2.9 Tests and Conclusions

Functional and performance testing has been conducted to assess the safety and effectiveness of Hylatopic™ Plus Emollient Foam and all results are satisfactory.

2.10 Performance Standards

To the best of our knowledge there are no performance standards applicable to these devices that have been adopted under section 514 of the Act.

3

Image /page/3/Picture/1 description: The image shows the logo for the U.S. Department of Health and Human Services. The logo consists of a stylized depiction of an eagle or bird-like figure with outstretched wings. The text "DEPARTMENT OF HEALTH & HUMAN SERVICES • USA" is arranged in a circular pattern around the bird symbol.

Food and Drug Administration 10903 New Hampshire Avenue Document Control Room W-O66-0609 Silver Spring, MD 20993-0002

Collegium Pharmaceutical, Inc. % Ronald M. Gurge, Ph.D. Associate Director Product Research & Development 400 Highland Corporate Drive Cumberland, Rhode Island 02864

DEC - 7 2009

Re: K093051

Trade/Device Name: Hylatopic™ Plus Emollient Foam Regulation Number: Unclassified Regulation Name: N/A Regulatory Class: N/A Product Code: FRO, MGQ Dated: September 29, 2009 Received: September 30, 2009

Dear Dr. Gurge:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA), You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21

4

Page 2 - Ronald M. Gurge, Ph.D.

CFR Part 807); labeling (21 CFR Part 801); medical device reporting (reporting of medical device-related adverse events) (21 CFR 803); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please . go to http://www.fda.gov/AboutFDA/CentersOffices/CDRH/CDRHOffices/ucm115809.htm for the Center for Devices and Radiological Health's (CDRH's) Office of Compliance. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to http://www.fda.gov/cdrh/mdr/ for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance.

You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 796-7100 or at its Internet address http://www.fda.gov/cdrh/industry/support/index.html.

Sincerely yours,

cerely yours,

Fell Pato Dero

Mark N. Melkerson Director Division of Surgical, Orthopedic and Restorative Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

5

K093057

Hylatopic™ Plus Emollient Foam

.:

510 (k) Premarket Notification CONFIDENTIAL

SECTION 1

SUBSECTION 1.8

GENERAL INFORMATION

Statement of Indications for Use

Statement of Indications for Use 1.8

510(k) Number (if known):_This submission

Device Name: Hylatopic™ Plus Emollient Foam

Indications For Use:

Under the supervision of a healthcare professional, Hylatopic™ Plus Emollient Foam, and Under the supervision of a neallicate professional Prynespected the burning, itching and pain
aerosol-based emollient foam, is indicated to manage and relieve states sontact aerosol-based emotivent foam, is murchise to may be dermatits, allergic contact.
experienced with various types of dermatoses, including atopic derelieve experienced with Various types of definatosos, Microang on Foam also helps to relieve dry, dermatus and radiation definatus. Trylatopte - Frids Entericial to the healing process.

Hylatopic™ Plus Emollient Foam is indicated for use in:

  • · Atopic Dermatitis
  • Allergic Contact Dermatitis .
  • Radiation Dermatitis .

X Prescription Use (Part 21 CFR 801 Subpart D) AND/OR

Over-The-Counter Use (21 CFR 807 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Daniel Krone for MXiy

(Division Sign-Off) Division of Surgical, Orthopedic, and Restorative Devices

510(k) Number K093051.

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