K Number
K083024
Device Name
HYLATOPIC EMOLLIENT FOAM
Date Cleared
2009-03-27

(169 days)

Product Code
Regulation Number
N/A
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
Under the supervision of a healthcare professional, Hylatopic™ Emollient Foam, an aerosolbased emollient foam. is indicated to manage and relieve the burning, itching and pain experienced with various types of dermatoses, including atopic dermatitis, allergic contact dermatitis and radiation dermatitis. Hylatopic™ Emollient Foam also helps to relieve dry, waxy skin by maintaining a moist wound & skin environment, which is beneficial to the healing process. Hylatopic TM Emollient Foam is indicated for use in: - · Atopic Dermatitis - Allergic Contact Dermatitis - Radiation Dermatitis .
Device Description
Hylatopic™ Emollient Foam is a non-steroidal, non-sterile, off-white, low odor, fragrance free, topical aerosol foam. When Hylatopic™ Emollient Foam is dispensed, foam is formed. The propellant in the foam dissipates very quickly and the foam is then rubbed on the affected skin. The Hylatopic™ Emollient Foam when applied to diseased skin forms a protective barrier that helps to maintain a moist wound and skin environment. This device is presented as a prescription product that requires the physician to diagnosis of the disease state and prescribes the product.
More Information

Not Found

No
The device description and intended use clearly define it as a topical emollient foam for managing dermatoses. There is no mention of any software, algorithms, or data processing that would indicate the use of AI or ML. The "Mentions AI, DNN, or ML" field is explicitly marked as "Not Found".

Yes
The device is indicated to "manage and relieve the burning, itching and pain experienced with various types of dermatoses" and "helps to relieve dry, waxy skin by maintaining a moist wound & skin environment, which is beneficial to the healing process," indicating a therapeutic purpose.

No

This device is an emollient foam used to manage and relieve symptoms of various dermatoses; it does not perform diagnostic functions.

No

The device description clearly states it is a "topical aerosol foam" and describes its physical properties and application, indicating it is a physical product, not software.

Based on the provided text, this device is not an IVD (In Vitro Diagnostic).

Here's why:

  • Intended Use: The intended use clearly states that Hylatopic™ Emollient Foam is indicated to manage and relieve symptoms of various dermatoses by being applied topically to the skin. This is a therapeutic application, not a diagnostic one.
  • Device Description: The description details a topical aerosol foam that forms a protective barrier on the skin. This aligns with a treatment for skin conditions, not a test performed on a sample outside the body.
  • Lack of IVD Characteristics: There is no mention of analyzing biological samples (blood, urine, tissue, etc.) or providing information for the diagnosis of a disease or condition. The device is applied directly to the affected area for symptomatic relief and to aid healing.

Therefore, Hylatopic™ Emollient Foam is a topical medical device intended for the management of skin conditions, not an in vitro diagnostic device.

N/A

Intended Use / Indications for Use

Under the supervision of a healthcare professional, Hylatopic™ Emollient Foam, an aerosolbased emollient foam. is indicated to manage and relieve the burning, itching and pain experienced with various types of dermatoses, including atopic dermatitis, allergic contact dermatitis and radiation dermatitis. Hylatopic™ Emollient Foam also helps to relieve dry, waxy skin by maintaining a moist wound & skin environment, which is beneficial to the healing process.

Hylatopic TM Emollient Foam is indicated for use in:

  • · Atopic Dermatitis
  • Allergic Contact Dermatitis
  • Radiation Dermatitis .

Product codes

MGQ

Device Description

Hylatopic™ Emollient Foam is a non-steroidal, non-sterile, off-white, low odor, fragrance free, topical aerosol foam. When Hylatopic™ Emollient Foam is dispensed, foam is formed. The propellant in the foam dissipates very quickly and the foam is then rubbed on the affected skin. The Hylatopic™ Emollient Foam when applied to diseased skin forms a protective barrier that helps to maintain a moist wound and skin environment. This device is presented as a prescription product that requires the physician to diagnosis of the disease state and prescribes the product.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

Not Found

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Under the supervision of a healthcare professional

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies (study type, sample size, AUC, MRMC, standalone performance, key results)

Functional and performance testing has been conducted to assess the safety and effectiveness of Hylatopic™ Emollient Foam and all results are satisfactory.

Key Metrics (Sensitivity, Specificity, PPV, NPV, etc.)

Not Found

Predicate Device(s)

K024367, K041342, K060272

Reference Device(s)

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information for the subject device only (e.g. presence / absence, what scope was granted / cleared under the PCCP, any restrictions, etc)

Not Found

N/A

0

c8/3024 1/3

510 (k) Premarket Notification CONFIDENTIAL

SECTION 2

510(K) Summary

2. 510(k) Summary

Image /page/0/Picture/6 description: The image shows the logo for Collegium Pharmaceutical. The logo consists of the letters "CP" on the left, with the word "COLLEGIUM" in all caps on the top right and the word "Pharmaceutical" on the bottom right. The letters and words are in a simple, sans-serif font.

2.1 510(k) Owner's Name

Collegium Pharmaceutical, Incorporated 400 Highland Corporate Drive Cumberland, RI 02864 Device Establishment Registration Number: Collegium Pharmaceutical intends to register as a manufacturer of medical

devices.

Contact Individual 2.2

Ronald M. Gurge, Ph.D. Associate Director, Product Research & Development Collegium Pharmaceutical, Incorporated 401-762-2000, Extension 41 401-762-2043 (fax) rgurge@collegiumpharma.com

2.3 Date Summary Prepared

October 7, 2008

2.4 510(k) Device Name

Proprietary Name: Common/Usual Name: Classification Name: Panel: CFR Number: Product code:

Hylatopic™ Emollient Foam Dressing, Wound & Burn, Hydrogel w/drug and/or biologic Dressing, Wound & Burn, Hydrogel w/drug and/or biologic General & Plastic Surgery Unclassified MGQ

fax 401 762 2043 400 Highland Corporate Drive · Cumberland, RI · 02864

MAR 2 7 2009

1

510 (k) Premarket Notification CONFIDENTIAL

SECTION 2

510(k) SUMMARY (Cont'd)

2.5 Devices to Which New Device is Substantially Equivalent

  • . Sinclair (Atopiclair™) Wound and Skin Emulsion approved under 510(k) K024367, from Sinclair Pharmaceuticals, Ltd.
  • MimyX™ Cream cleared approved 510(k) K041342, from Stiefel Laboratories, Inc. .
  • Locobase® Wound and Skin Emulsion approved under 510(k) K060272, from . Ferndale Laboratories, Inc.

2.6 Device Description

Hylatopic™ Emollient Foam is a non-steroidal, non-sterile, off-white, low odor, fragrance free, topical aerosol foam. When Hylatopic™ Emollient Foam is dispensed, foam is formed. The propellant in the foam dissipates very quickly and the foam is then rubbed on the affected skin. The Hylatopic™ Emollient Foam when applied to diseased skin forms a protective barrier that helps to maintain a moist wound and skin environment. This device is presented as a prescription product that requires the physician to diagnosis of the disease state and prescribes the product.

2.7 Intended Use of the Device

Under the supervision of a healthcare professional, Hylatopic™ Emollient Foam, an aerosol-based emollient foam. is indicated to manage and relieve the burning, itching and pain experienced with various types of dermatoses, including atopic dermatitis, allergic contact dermatitis and radiation dermatitis. Hylatopic™ Emollient Foam also helps to relieve dry, waxy skin by maintaining a moist wound & skin enviromment, which is beneficial to the healing process.

Hylatopic™ Emollient Foam provides a non-steroidal alternative for the management of symptoms associated with various types of dermatoses.

Summary of Technological Characteristics of the Device Compared to the Predicate 2.8 Devices

All predicate devices referenced are non-sterile, emulsion/gel/cream types that are applied topically to relieve the symptoms of various dermatoses. When Hylatopic™ Emollient Foam is dispensed, foam is formed. The propellant in the foam dissipates very quickly and the foam is then rubbed on the affected skin. The rubbed in product is equivalent to a gel or cream.

2

KOY 30-24 3/3

510 (k) Premarket Notification CONFIDENTIAL

SECTION 2

510(k) SUMMARY (Cont'd)

2.9 Tests and Conclusions

Functional and performance testing has been conducted to assess the safety and effectiveness of Hylatopic™ Emollient Foam and all results are satisfactory.

2.10 Performance Standards

To the best of our knowledge there are no performance standards applicable to these devices that have been adopted under section 514 of the Act.

3

DEPARTMENT OF HEALTH & HUMAN SERVICES

Image /page/3/Picture/1 description: The image shows the seal of the Department of Health & Human Services (HHS). The seal features an eagle with its wings spread, surrounded by the words "DEPARTMENT OF HEALTH & HUMAN SERVICES • USA". The eagle is stylized with three thick lines forming its body and wings. The seal is circular and appears to be in black and white.

Public Health Service

MAR 2 7 2009

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

Collegium Pharmaceutical, Incorporated % Ronald M. Gurge, Ph.D Associate Director, Product Research & Developoment 400 Highland Corporate Drive Cumberland, Rhode Island

Re: K083024

Trade/Device Name: Hylatopic™ Emollient Foam Regulatory Class: Unclassified Product Code: MGQ Dated: March 24, 2009 Received: March 25, 2009

Dear Dr. Gurgc:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

4

Page 2 - Ronald M. Gurge, Ph.D

This letter will allow you to begin marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Center for Devices and Radiological Health's (CDRH's) Office of Compliance at (240) 276-0115. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding postmarket surveillance, please contact CDRH's Office of Surveillance and Biometric's (OSB's) Division of Postmarket Surveillance at (240) 276-3474. For questions regarding the reporting of device adverse events (Medical Device Reporting (MDR)), please contact the Division of Surveillance Systems at (240) 276-3464. You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (240) 276-3150 or at its Internet address http://www.fda.gov/cdrh/industry/support/index.html.

Sincerely yours,

L. Aimer. for.

Mark N. Melkerson Director Division of General, Restorative, and Neurological Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

5

K09 3024 1//

510 (k) Premarket Notification CONFIDENTIAL

SECTION 1

SUBSECTION 1.8

GENERAL INFORMATION

Statement of Indications for Use

1.8 Statement of Indications for Use

510(k) Number (if known): This submission

Device Name: Hylatopic™ Emollient Foam

Indications For Use:

Under the supervision of a healthcare professional, Hylatopic™ Emollient Foam, an aerosolbased emollient foam. is indicated to manage and relieve the burning, itching and pain experienced with various types of dermatoses, including atopic dermatitis, allergic contact dermatitis and radiation dermatitis. Hylatopic™ Emollient Foam also helps to relieve dry, waxy skin by maintaining a moist wound & skin environment, which is beneficial to the healing process.

Hylatopic TM Emollient Foam is indicated for use in:

  • · Atopic Dermatitis
  • Allergic Contact Dermatitis
  • Radiation Dermatitis .

Prescription Use X (Part 21 CFR 801 Subpart D) AND/OR

Over-The-Counter Use (21 CFR 807 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Daniel Krone for MXU 3/27/09

(Division Sign-Off) Division of General, Restorative, and Neurological Devices

510(k) Number K083024