K Number
K033436
Date Cleared
2005-03-16

(505 days)

Product Code
Regulation Number
870.1200
Reference & Predicate Devices
Predicate For
N/A
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

Reprocessed Diagnostic Ultrasound Catheters are intended for intravascular or intracardiac ultrasound imaging in order to provide visualization of vascular anatomy, cardiac and great vessel anatomy and physiology, or other devices in the heart. The device is intended for use in the right heart only.

Reprocessed Diagnostic Ultrasound Catheters are indicated for visualization of vascular anatomy, cardiac and great vessel anatomy and physiology, or other devices in the heart, as well as measurement of blood flow. The Reprocessed Diagnostic Ultrasound Catheter is intended for use in the right side of the heart only.

Device Description

Diagnostic ultrasound catheters are specially designed ultrasonic catheters that provide two-dimensional imaging using an ultrasound transducer. The ultrasound transducer is at the distal tip of the catheter and can be positioned for ultrasound imaging by a steering mechanism that rotates the catheter tip and variable deflection. Diagnostic ultrasound catheters incorporate a handpiece, a flexible shaft and a distal tip section containing an ultrasound transducer. The ultrasound catheter is 10 French with 90 cm insertion length.

AI/ML Overview

The provided text describes the reprocessed ultrasound catheter by Alliance Medical Corporation and references a 510(k) submission (K033436). However, the document does not contain specific acceptance criteria, detailed results of a study proving the device meets those criteria, or information on specific statistical analyses like MRMC studies or effect sizes for human readers.

The document primarily focuses on establishing substantial equivalence to a predicate device (AcuNav™ Diagnostic Ultrasound Catheter, K992631) based on identical design, materials, intended use, clinical applications, performance specifications, and method of operation.

Here's an attempt to answer the questions based on the available information, noting where data is absent:

1. A table of acceptance criteria and the reported device performance

The document states that "Bench and laboratory testing was conducted to demonstrate performance (safety and effectiveness) of the Reprocessed Ultrasound Catheters." The performance data reported are categories of testing, not specific quantitative criteria or results.

Acceptance Criterion (Implicit)Reported Device Performance
Biocompatibility requirements metBiocompatibility testing performed. Conclusion: "Reprocessed Ultrasound Catheters perform as originally intended."
Reprocessing process validatedValidation of reprocessing performed. Conclusion: "Reprocessed Ultrasound Catheters perform as originally intended."
Sterilization process validatedSterilization Validation performed. Conclusion: "Reprocessed Ultrasound Catheters perform as originally intended."
Functional equivalence to original deviceFunction test(s) performed. Conclusion: "Reprocessed Ultrasound Catheters perform as originally intended." (Also states "same standard," "identical")
Packaging integrity maintained after reprocessing/sterilizationPackaging Validation performed. Conclusion: "Reprocessed Ultrasound Catheters perform as originally intended."

2. Sample size used for the test set and the data provenance (e.g. country of origin of the data, retrospective or prospective)

The document does not specify the sample size for any of the performance tests (biocompatibility, reprocessing validation, sterilization validation, function tests, packaging validation). It also does not explicitly state the provenance of the data (country of origin) or whether the tests were retrospective or prospective. Given the nature of bench and laboratory testing, it is generally prospective.

3. Number of experts used to establish the ground truth for the test set and the qualifications of those experts (e.g. radiologist with 10 years of experience)

This information is not provided in the document. The document describes technical performance tests, not studies involving expert interpretation of medical images or data.

4. Adjudication method (e.g. 2+1, 3+1, none) for the test set

This information is not applicable and not provided. The testing described is technical performance validation, not human-read clinical evaluation requiring adjudication.

5. If a multi reader multi case (MRMC) comparative effectiveness study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

No such study (MRMC comparative effectiveness with human readers and AI assistance) is mentioned or implied in the document. This device is a reprocessed physical medical device, not an AI diagnostic tool.

6. If a standalone (i.e. algorithm only without human-in-the-loop performance) was done

This question is not applicable as the device is a reprocessed physical medical device, not an algorithm or AI system.

7. The type of ground truth used (expert concensus, pathology, outcomes data, etc)

For the technical performance tests mentioned (biocompatibility, reprocessing, sterilization, function, packaging), the "ground truth" would be established by validated test methodologies and specifications, comparing the reprocessed device's performance against the original device's specifications or established safety standards. It does not involve expert consensus on medical images, pathology, or outcomes data in the clinical sense.

8. The sample size for the training set

This question is not applicable to this type of device. There is no mention of a "training set" as this is not an AI/machine learning device.

9. How the ground truth for the training set was established

Not applicable.

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KO33436 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

MAR 1 6 2005

Alliance Medical Corporation

Submitter:

Image /page/0/Picture/2 description: The image shows a logo with three curved lines above the word "ALLIANCE". The lines are thick and black, and they curve upwards and to the right. The word "ALLIANCE" is written in a simple sans-serif font, and it is located directly below the curved lines. The logo is simple and modern, and it is likely used to represent a company or organization.

ALLIANCE

SECTION B: 510(k) SUMMARY

10232 South 5 Ist Street Phoenix, Arizona 85044

ILL 480.763.5300
FAX 480.763.5310 Tالا Free 888.888.3433 www.alliance-medical.com

Submitter:Alliance Medical Corporation10232 South 51 st StreetPhoenix, Arizona 85044
Contact:Moira BartonRegulatory Affairs Manager(480) 763-5350 (o)(480) 763-5310 (f)mbarton@alliance-medical.com
Date of preparation:October 3, 2003
Name of device:Trade/Proprietary Name: Reprocessed Ultrasound CatheterCommon or Usual Name: Diagnostic Ultrasound Transducer CatheterClassification Name: Catheter, Intravascular, Diagnostic
Predicate device:AcuNav™ Diagnostic Ultrasound Catheter
K992631
Device description:Diagnostic ultrasound catheters are specially designedultrasonic catheters that provide two-dimensional imaging usingan ultrasound transducer. The ultrasound transducer is at thedistal tip of the catheter and can be positioned for ultrasoundimaging by a steering mechanism that rotates the catheter tipand variable deflection. Diagnostic ultrasound cathetersincorporate a handpiece, a flexible shaft and a distal tip sectioncontaining an ultrasound transducer. The ultrasound catheter is10 French with 90 cm insertion length.
Intended use:Reprocessed Diagnostic Ultrasound Catheters are intended forintravascular or intracardiac ultrasound imaging in order toprovide visualization of vascular anatomy, cardiac and greatvessel anatomy and physiology, or other devices in the heart.The device is intended for use in the right heart only.
Indications statement:Reprocessed Diagnostic Ultrasound Catheters are indicated forvisualization of vascular anatomy, cardiac and great vesselanatomy and physiology, or other devices in the heart, as wellas measurement of blood flow. The Reprocessed DiagnosticUltrasound Catheter is intended for use in the right side of theheart only.
Technological characteristics:The design, materials, and intended use of ReprocessedUltrasound Catheters are identical to the predicate devices. The

Alliance Medical Corporation
Reprocessed Ultrasound Catheters
Traditional 510(k)10

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mechanism of action of Reprocessed Ultrasound Catheters is mechanism of dotion of dotion of that the same standard luentical to the prodicate cals and sizes are utilized. There are mochaniour doolig intended use, clinical applications, no changes to the claim ance specifications, or method of operation.

Alliance Medical Corporation's reprocessing of ultrasound Allianoo Moules removal of adherent visible soil and catheters indiados rom individual ultrasound catheter is tested for appropriate function of its components prior to packaging and labeling operations.

Bench and laboratory testing was conducted to demonstrate Performance data: performance (safety and effectiveness) of the Reprocessed Ultrasound Catheters.

  • Biocompatibility .
  • Validation of reprocessing .
  • Sterilization Validation .
  • Function test(s) .
  • Packaqing Validation ●

Performance testing demonstrates that Reprocessed Ultrasound Catheters perform as originally intended.

Conclusion:

Alliance Medical Corporation concludes that the modified device (the Reprocessed Ultrasound Catheter) is safe, effective and substantially equivalent to the predicate devices as described herein.

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Image /page/2/Picture/2 description: The image shows the logo for the U.S. Department of Health and Human Services. The logo features a stylized image of an eagle with three lines forming its body and wings. The text "DEPARTMENT OF HEALTH AND HUMAN SERVICES - USA" is arranged in a circular pattern around the eagle. The logo is black and white.

SEP - 6 2006

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

Alliance Medical Corporation c/o Ms. Moira Barton Regulatory Affairs Manager 10232 South 51st Street Phoenix, Arizona 85044

Re: K033436

Trade/Device Name: Reprocessed Ultrasound Catheter Regulation Number: 21 CFR 870.1200 Regulation Name: Diagnostic Intravascular Catheter Regulatory Class: II (Two) Product Code: NLI Dated: January 19, 2004 Received: January 21, 2005

Dear Ms. Barton:

This letter corrects our substantially equivalent letter of March 16, 2005.

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug. and Cosmetic Act (Act) that do not require approval of a premarket approval (PMA). You may. therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA). it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

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Page 2 - Ms. Moira Barton

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (sections 531-542 of the Act); 21 CFR 1000-1050.

This letter will allow you to continue marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Office of Compliance at (240) 276-0120. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (240) 276-3150 or at its Internet address http://www.fda.gov/cdrh/dsma/dsmamain.html

Sincerely yours,

B. Bimiena for

Bram D. Zuckerman, M.D. Director Divison of Cardioascular Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure (2)

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Page 3 - Ms. Moira Barton

Original model found to be SE
AccuNavTM Diagnostic Ultrasound Catheter, Model
08255790

:

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Indications for Use Statement 2.

510(k) Number (if known): KO33434

Device Name: Alliance Medical Corporation Reprocessed Ultrasound Catheter

Indications for Use: Reprocessed Diagnostic Ultrasound Catheters are Indications for Use: Replocessed Diagnosus Cardiac and great vessel anatomy
indicated for visualization of vascular anatomy, cardiac mazurement of blood indicated for visualization of vascular analy, barantes, as well as measurement of blood
and physiology, or other devices in the heart, as well as measurement of blood and physiology, or other devices in the nearly as well as work in the first in the right side of the heart only.

Prescription Use _ (per 21 CFR 801.109) ਾ

Over-the-Counter Use _________________________________________________________________________________________________________________________________________________________

Concurrence of CDRH, Office of Device Evaluation (ODE)

Blummlamar

(Division Sign-Off) Division of Cardiovascular Devices 510(k) Numbər _

§ 870.1200 Diagnostic intravascular catheter.

(a)
Identification. An intravascular diagnostic catheter is a device used to record intracardiac pressures, to sample blood, and to introduce substances into the heart and vessels. Included in this generic device are right-heart catheters, left-heart catheters, and angiographic catheters, among others.(b)
Classification. Class II (performance standards).