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510(k) Data Aggregation

    K Number
    K220284
    Date Cleared
    2022-07-08

    (157 days)

    Product Code
    Regulation Number
    880.6250
    Reference & Predicate Devices
    Predicate For
    N/A
    AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
    Intended Use

    A patient examination glove is a disposable device intended for medical purposes that is worn on the examiner's hands or fingers to prevent contamination between patient and examiner.

    Device Description

    Powder Free Blue Nitrile Examination Glove meets all the current specifications listed under the ASTM Specification D6319-19, Standard Specification for Nitrile Examination Gloves for Medical Application. The principle operation and mechanism of this device is to prevent contamination between patient and examiner and this principle is achieved through testing of barrier, physical properties and other testing stated in the performance data. This device is for over-the counter single use.

    AI/ML Overview

    The document provided describes the acceptance criteria and performance data for a Powder Free Nitrile Examination Glove (Blue), K220284, in comparison to a predicate device. This is a medical device submission, and the studies described are non-clinical performance data to demonstrate substantial equivalence, not studies related to AI or diagnostic algorithms. Therefore, many of the requested fields related to AI/algorithm performance (e.g., MRMC studies, standalone performance, training set details) are not applicable.

    Here's the information that can be extracted:

    1. Table of Acceptance Criteria and Reported Device Performance

    Test MethodologyPurposeAcceptance CriteriaReported Device PerformanceResult
    ASTM D6319-19: DimensionsTo measure the physical length and width of the glovesLength: XS-Min 220mm, S-Min 220mm, M-Min 230mm, L-Min 230mm, XL-Min 230mmMinimal Value for Length: XS: 240mm, S: 246mm, M: 240mm, L: 250mm, XL: 251mmPASS
    Width: XS-70 ± 10mm, S-80 ± 10mm, M-95 ± 10mm, L-110 ± 10mm, XL-120 ± 10mmMinimal Value for Width: XS: 73mm, S: 84mm, M: 93mm, L: 104mm, XL: 111mmPASS
    ASTM D6319-19: Physical PropertiesTo measure the tensile strength and elongation before and after agingTensile Strength: Before Aging: 14.0 MPa, After Aging: 14.0 MPaTensile Strength: Before Aging: Minimal Value: 19.10 MPa, After Accelerated Aging: Minimal Value: 19.0 MPaPASS
    Ultimate Elongation: Before Aging: min. 500%, After Aging: min. 400%Ultimate Elongation: Before Aging Minimal Value: 520%, After Aging Minimal Value: 480%PASS
    ASTM D6319-19: ThicknessTo measure the physical palm and finger thickness of the glovesPalm-Min. 0.05mmPalm Minimal Value: XS: 0.07mm, S: 0.07mm, M: 0.07mm, L: 0.07mm, XL: 0.07mmPASS
    Finger-Min. 0.05mmFinger Minimal Value: XS: 0.11mm, S: 0.11mm, M: 0.11mm, L: 0.11mm, XL: 0.12mmPASS
    ASTM D6319-19: Freedom from Holes TestingTo detect the presence of holes in gloveMeet AQL 2.5 at G1Meet AQL 2.5 at G1PASS
    ISO 10993-10: Primary Skin IrritationTo determine the irritation potential of glove when exposed to skin surfaceNot an irritantUnder the condition of study, not an irritantPASS
    ISO 10993-10: Dermal SensitizationTo determine the sensitization potential of glove when exposed to skin surfaceNot a SensitizerUnder the condition of study, not a sensitizerPASS
    ISO 10993-11: Acute Systemic ToxicityTo evaluate the adverse systemic reaction potential from gloveNot induce systemic toxicityDid not induce systemic ToxicityPASS
    ASTM D6124-06: Residual Powder AnalysisTo check the amount of powder residue from glove surfaceResidual powder test (< 2 mg/glove)Average 0.10mg/glovePASS

    2. Sample size used for the test set and the data provenance

    The document specifies "Minimal Value" and "Average" for various measurements, indicating that multiple samples were tested, but it does not provide the exact sample size for each test (e.g., number of gloves tested for dimensions, physical properties, etc.).

    Data provenance: The testing was performed by KGM Gloves Sdn. Bhd. for their own device. The location of the manufacturer is Malaysia. The testing data is non-clinical performance data, likely gathered prospectively as part of product development and quality control.

    3. Number of experts used to establish the ground truth for the test set and the qualifications of those experts

    Not applicable. The "ground truth" here refers to objective physical and chemical properties measured by standardized tests (e.g., ASTM and ISO standards) and laboratory procedures, not expert interpretation of medical images or other subjective assessments.

    4. Adjudication method for the test set

    Not applicable. The tests involve objective measurements and standardized protocols, not human adjudication.

    5. If a multi reader multi case (MRMC) comparative effectiveness study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

    Not applicable. This document is for a physical medical device (examination gloves), not an AI-powered diagnostic or assistive tool.

    6. If a standalone (i.e. algorithm only without human-in-the-loop performance) was done

    Not applicable. This is not an algorithmic device.

    7. The type of ground truth used

    The ground truth used consists of objective measurements and laboratory test results against established international and national standards (ASTM D6319-19, ISO 10993-10, ISO 10993-11, ASTM D6124-06). For example, a glove's length is its measured length, and its tensile strength is the result obtained from the specified test method.

    8. The sample size for the training set

    Not applicable. There is no "training set" as this is not a machine learning/AI device.

    9. How the ground truth for the training set was established

    Not applicable. There is no "training set" as this is not a machine learning/AI device.

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