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510(k) Data Aggregation

    K Number
    K212182
    Date Cleared
    2021-12-11

    (151 days)

    Product Code
    Regulation Number
    880.6250
    Reference & Predicate Devices
    Predicate For
    N/A
    AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
    Intended Use

    This non-powdered patient examination glove is a disposable device intended for medical purposes that is worn on the examiner's hand to prevent contamination between patient and examiner.

    Device Description

    The subject device in this 510(k) Notification is Iconic Nitrile Glove - Powder Free Nitrile Examination Glove. The subject device is a patient examination glove made from Nitrile compound, Blue color, powder free and non-sterile (Per 21 CFR 880.6250, class I). The device meets the specifications in ASTM D6319-19 Standard specification for Nitrile Examination Gloves. The available sizes of the subject devices are Small, Medium, Large, X-Large.

    AI/ML Overview

    The provided text describes the acceptance criteria and the results of a study for the "Iconic Nitrile Glove," a non-powdered patient examination glove.

    Here's the breakdown of the requested information:

    1. A table of acceptance criteria and the reported device performance

    Characteristics/Test MethodologyPurposeAcceptance CriteriaReported Device Performance (Average Results)Final Status
    Freedom from hole - ASTM D5151-19Freedom from holeAQL 2.5Non sterile (for all sizes: Small, Medium, Large, X-Large)Pass
    DimensionsOverall Length (mm)Min 230mmSmall: 234.9, Medium: 246, Large: 236.5, X-Large: 241.0Pass
    DimensionsWidth (±10mm)Small - 80, Medium- 95, Large-110, X-large-120Small: 84.7, Medium: 97.4, Large: 106.4, X-Large: 114.6Pass
    DimensionsThickness at PalmMin: 0.05 mmSmall: 0.10, Medium: 0.06, Large: 0.08, X-Large: 0.09Pass
    DimensionsThickness at FingertipMin: 0.05 mmSmall: 0.12, Medium: 0.10, Large: 0.13, X-Large: 0.13Pass
    ASTM D6319-19 (Before Aging)Physical properties before aging - Tensile Strength14 MPa, min.Small: 21.2, Medium: 25, Large: 18.9, X-Large: 18.4Pass
    ASTM D6319-19 (Before Aging)Physical properties before aging - Ultimate Elongation500 % minSmall: 896.3, Medium: 893.8, Large: 919.7, X-Large: 930.9Pass
    ASTM D6319-19 (After Accelerated Aging)Physical properties after accelerated aging - Tensile Strength14 MPa, min.Small: 23.5, Medium: 26.8, Large: 22.2, X-Large: 19.3Pass
    ASTM D6319-19 (After Accelerated Aging)Physical properties after accelerated aging - Ultimate Elongation400 % minSmall: 879.2, Medium: 787.9, Large: 855.3, X-Large: 858.6Pass
    Powder-free Residue - ASTM D6124-06Powder-free Residue< 2.0 mg per gloveSmall: 0.78, Medium: 0.24, Large: 0.38, X-Large: 0.54Pass
    ISO 10993-5Test for Invitro cytotoxicityCytotoxic Characteristics (Pass)PassPass
    ISO 10993-10Test for irritation and Skin SensitizationNon - Skin Sensitized (Pass)PassPass
    ISO 10993-11Tests for systemic toxicityNot induce systemic toxicity (Pass)PassPass
    ISO 10993-23Tests for irritationNon-Irritant (Pass)PassPass

    2. Sample size used for the test set and the data provenance
    The document does not explicitly state the sample size for each test (e.g., how many gloves were tested for pinholes, or how many samples for biocompatibility). However, it refers to standard methodologies like ASTM D6319-19, ASTM D5151-19, ASTM D6124-06, and ISO 10993 series, which inherently define sample sizes for achieving statistical significance. The data provenance is not specified beyond the fact that the tests were conducted for "Iconic Medicare Sdn Bhd" located in Malaysia. It is a non-clinical, laboratory-based testing scenario.

    3. Number of experts used to establish the ground truth for the test set and the qualifications of those experts
    Not applicable. For this type of device (nitrile gloves), the ground truth is established through adherence to standardized international test methods (ASTM and ISO standards) and their specific acceptance criteria, rather than expert consensus on subjective observations.

    4. Adjudication method for the test set
    Not applicable. As the ground truth is based on quantitative measurements and adherence to specified standard criteria, no human adjudication method (like 2+1 or 3+1) is mentioned or implied.

    5. If a multi-reader multi-case (MRMC) comparative effectiveness study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance
    Not applicable. This device is a nitrile glove, not an AI-powered diagnostic or assistance tool. Therefore, an MRMC study is irrelevant.

    6. If a standalone (i.e. algorithm only without human-in-the-loop performance) was done
    Not applicable. This device is a nitrile glove, not an algorithm.

    7. The type of ground truth used
    The ground truth is established by adherence to internationally recognized standards (ASTM D6319-19, ASTM D5151-19, ASTM D6124-06, ISO 10993-5, ISO 10993-10, ISO 10993-11, ISO 10993-23) which define specific physical, mechanical, and biological properties and their acceptance limits.

    8. The sample size for the training set
    Not applicable. This is not an AI/machine learning device, so there is no concept of a "training set."

    9. How the ground truth for the training set was established
    Not applicable, as there is no training set for this device.

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