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510(k) Data Aggregation

    K Number
    K211516
    Date Cleared
    2021-08-24

    (99 days)

    Product Code
    Regulation Number
    880.6250
    Reference & Predicate Devices
    Predicate For
    N/A
    AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
    Intended Use

    A patient examination glove is a disposable device intended for medical purposes that is worn upon the examiner's hands to prevent contamination between patient and examiner.

    Device Description

    The subject device is powder free vinyl synthetic patient examination gloves. The subject device is blue. The design of subject device is addressing the standards as ASTM D6124, ASTM D5151, and ASTM D5250. The subject device is non-sterile.

    AI/ML Overview

    The provided text is a 510(k) Summary for a medical device, "Disposable Vinyl Nitrile Synthetic Gloves Powder Free" (K211516). This document details the device's characteristics and its equivalence to a predicate device, as submitted to the FDA.

    Based on the nature of the device (disposable patient examination gloves) and the content of the summary, the "device" in question is not an AI/ML-driven diagnostic or assistive technology. Instead, it is a physical medical device. Therefore, the questions related to AI/ML device performance metrics (such as MRMC studies, standalone algorithm performance, number of experts for ground truth, training set size, etc.) are not applicable to this document.

    The acceptance criteria and performance are related to the physical properties, safety, and regulatory compliance of the gloves.

    Here's the information that can be extracted from the provided text, related to the device's acceptance criteria and how it meets them:

    1. A table of acceptance criteria and the reported device performance

    Test MethodologyPurposeAcceptance CriteriaReported Device PerformanceResult
    ASTM D5250Physical DimensionsLength: ≥230 mm Width (S): 85±5 mm Width (M): 95±5 mm Width (L): 105±5 mm Width (XL): 115±5 mm Thickness (Finger): ≥0.08 mm Thickness (Palm): ≥0.08 mmLength: >230 mm Width (S): 88-90 mm Width (M): 95-97 mm Width (L): 106-108 mm Width (XL): 113-116 mm Finger Thickness: 0.08-0.10 mm Palm Thickness: 0.09 mmPass
    ASTM D5151WatertightnessMeet the requirements of ASTM D5151 AQL 2.50/125 leaksPass
    ASTM D6124Powder ContentMeet the requirements of ASTM D6124 < 2.0 mg0.11 mg/glovePass
    ASTM D412Physical properties (Before Aging)Tensile Strength: ≥11 MPa Ultimate Elongation: ≥300%Tensile Strength: 15.2-17.8 MPa Ultimate Elongation: 417-606%Pass
    ASTM D412Physical properties (After Aging)Tensile Strength: ≥11 MPa Ultimate Elongation: ≥300%Tensile Strength: 12.4-16.9 MPa Ultimate Elongation: 370-568%Pass
    ISO 10993-5CytotoxicityNon-cytotoxicUnder conditions of the study, did not show potential toxicity to L-929 cells.Pass
    ISO 10993-10IrritationNon-irritatingUnder the conditions of the study, not an irritant.Pass
    ISO 10993-10SensitizationNon-sensitizingUnder conditions of the study, not a sensitizer.Pass

    2. Sample size used for the test set and the data provenance

    • Sample Size for Physical/Performance Tests: The specific sample sizes for each physical test (e.g., number of gloves tested for dimensions, powder content, or tensile strength) are not explicitly stated for all tests. For the watertightness test (ASTM D5151), the result "0/125 leaks" implies a sample size of 125 units were tested.
    • Data Provenance: The document does not specify the country of origin for the test data for the subject device beyond the manufacturer being in China. The tests are "non-clinical" (laboratory-based physical and biocompatibility testing), not human clinical studies. The data would be prospective as it's generated specifically for this submission.

    3. Number of experts used to establish the ground truth for the test set and the qualifications of those experts

    Not applicable. This is not an AI/ML device requiring expert adjudication/ground truth for image interpretation or diagnosis. The "ground truth" for these physical and biocompatibility tests is based on established laboratory testing methodologies and international standards (ASTM, ISO).

    4. Adjudication method (e.g. 2+1, 3+1, none) for the test set

    Not applicable. Adjudication methods are typically for human interpretation of data in studies, not for standardized physical/chemical/biocompatibility testing of a physical product.

    5. If a multi-reader multi-case (MRMC) comparative effectiveness study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

    Not applicable. This is not an AI/ML device.

    6. If a standalone (i.e. algorithm only without human-in-the-loop performance) was done

    Not applicable. This is not an AI/ML device. Performance is of the physical glove itself, not an algorithm.

    7. The type of ground truth used (expert consensus, pathology, outcomes data, etc)

    The "ground truth" for the device's performance is based on established international standards and laboratory testing protocols (ASTM D5250, ASTM D6124, ASTM D5151, ASTM D412, ISO 10993-5, ISO 10993-10). These standards define the methodologies and acceptance criteria for physical, chemical, and biological properties of examination gloves.

    8. The sample size for the training set

    Not applicable. There is no "training set" as this is not an AI/ML device.

    9. How the ground truth for the training set was established

    Not applicable.

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