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510(k) Data Aggregation

    K Number
    K101465
    Date Cleared
    2010-12-13

    (201 days)

    Product Code
    Regulation Number
    872.3630
    Panel
    Dental
    Reference & Predicate Devices
    Predicate For
    AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
    Intended Use

    The Straumann® CARES® Screw-retained Bridge and Straumann® CARES® Dolder® Bar are indicated for use as bars and bridges that attach to dental implants (Straumann RN (Reqular Neck) Ø4.8mm and WN (Wide Neck) Ø6.5mm) in the treatment of partially or totally edentulous jaws for the purpose of restoring chewing function.

    The Straumann® CARES® Screw-retained Bridge is available in different sizes and spans and can be fitted on 2 to 16 implants.

    The Straumann® CARES® Dolder® Bar is available in different sizes and spans and can be fitted on 2 to 10 implant.

    Device Description

    Straumann® CARES® Screw-Retained Bridges and Straumann® CARES® Dolder® Bars are dental restorative devices intended to be attached directly to dental implants by basel screws. The Straumann CARES Screw-Retained Bridge and Straumann CARES Dolder Bar are designed with implant interfaces comparable to a single tooth abutment which are attached to a Straumann implant RN (Regular Neck) Ø 4.8 mm and WN (Wide Neck) Ø 6.5 mm.

    The implant positions and oral situation are recognized by a scan of a dental master model with implant analogs and scanbodies. Based on the scan data, the dental technician selects the proper implant interfaces and designs the bar or bridge according to a dentist's prescription.

    Once the Straumann CARES Screw-Retained Bridge or Straumann CARES Dolder Bar is designed, the digital dataset is sent to Straumann CADCAM by an internet connection where the bridge or bar is milled from a cobaltchromium-based blank.

    Straumann CARES Screw-Retained Bridges and Straumann CARES Dolder Bars allow for individual customization regarding function and esthetics. They attach directly to Straumann dental implants. The device is intended to be finished into a bridge or overdenture using standard dental laboratory techniques and materials. The devices are CAD-derived, CAMproduced and have a scanner as its data source.

    The milling blanks used for the manufacture of Straumann CARES Screw-Retained Bridge and Straumann CARES Dolder Bar are manufactured from a cobalt chromium base metal alloy, which has been tested and found biocompatible for its intended use. The cobalt chromium alloy meets the physical and mechanical requirements of ISO 22674, Dentistry - Metallic materials for fixed and removable restorations and appliances and ISO 9693, Metal-ceramic dental restorative systems.

    AI/ML Overview

    The provided 510(k) summary for the Straumann® CARES® Screw-Retained Bridge and Straumann® CARES® Dolder® Bar describes non-clinical testing to demonstrate substantial equivalence to predicate devices. This submission focuses on material properties, biocompatibility, and mechanical performance rather than AI-driven insights or diagnostic accuracy. Therefore, many standard AI/ML study components, such as sample size for test/training sets, expert qualifications for ground truth, adjudication methods, and MRMC studies, are not applicable here.

    Here's an analysis of the provided information:

    1. Table of Acceptance Criteria and Reported Device Performance

    The acceptance criteria and performance are presented in several tables within the document for different aspects of the device.

    Table 1: Metallic Material Properties (Derived from Table 2 in document)

    PropertyUnitAcceptance Criteria with and without Thermal TreatmentConclusion
    ColornaSilver grayPassed
    Densityg/cm³8.3Passed
    Solubility in watermg/linsolublePassed
    Proof strength Rp0.2MPa> 360Passed
    Vickers hardnessHV10260na
    Elongation after fracture%> 2.0Passed
    CTE (25-500°C)10-6 K-114.4na
    Solidus°C1320na
    Liquidus°C1420na

    Table 2: Ceramic Bonding Properties (Derived from Table 3 in document)

    Veneering PorcelainDebonding/Crack-Initiation Strength $\tau_b$ [MPa]Acceptance CriterionConclusion
    Initial MC (GC)> 25 MPaN/A (implied from results)Passed
    IPS InLine (Ivoclar Vivadent)> 25 MPaN/A (implied from results)Passed
    HeraCeram (Heraeus Kulzer)> 25 MPaN/A (implied from results)Passed
    VM13 (Vita Zahnfabrik)> 25 MPaN/A (implied from results)Passed

    Table 3: Biocompatibility Testing (Derived from Table 4 in document)

    Test MethodBiocompatibility Acceptance CriteriaResults
    Cytotoxicity of extract< 30 %Passed
    Organic leachables qualitativenana
    Leachables quantitativenana

    Table 4: Static Corrosion Testing (Derived from Table 5 in document)

    Composite MaterialUnitsAcceptance CriterionResults
    Cobalt (Co)µg/cm²≤ 100Passed
    Chromium (Cr)µg/cm²≤ 100Passed
    Aluminum (Al)µg/cm²≤ 100Passed
    Titanium (Ti)µg/cm²≤ 100Passed
    Niobium (Nb)µg/cm²≤ 100Passed
    Tungsten (W)µg/cm²≤ 100Passed
    Silicon (Si)µg/cm²≤ 100Passed
    Manganese (Mn)µg/cm²≤ 100Passed
    Iron (Fe)µg/cm²≤ 100Passed
    Beryllium (Be)µg/cm²≤ 100Passed
    Cadmium (Cd)µg/cm²≤ 100Passed

    Table 5: Dynamic Fatigue Testing (Derived from Table 6 in document)

    Composite MaterialResults
    Minimal body testing (Connection testing)Passed
    Free hanging bridge (Connector testing)Passed
    Free end pontic bridge (Connector testing)Passed

    2. Sample size used for the test set and the data provenance

    The document specifies "Non-Clinical Testing" was performed. However, it does not specify the sample size for individual tests (e.g., number of samples for proof strength, number of samples for cytotoxicity). It also does not mention data provenance (e.g., country of origin, retrospective or prospective) as the testing is related to manufacturing material properties, not patient data.

    3. Number of experts used to establish the ground truth for the test set and the qualifications of those experts

    This information is not applicable to this submission. The "ground truth" here is based on internationally recognized standards (ISO 22674, ISO 9693) and established material science and biocompatibility testing methodologies, not expert interpretation of medical images or patient records. The results are quantitative measurements against predefined criteria.

    4. Adjudication method for the test set

    This is not applicable as the tests involve objective, quantitative measurements against predefined criteria, not subjective interpretations requiring adjudication.

    5. If a multi-reader multi-case (MRMC) comparative effectiveness study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

    This is not applicable. This submission is for a medical device (dental bridge/bar) and its material properties and manufacturing process, not an AI/ML diagnostic or assistive device. There are no "human readers" or AI assistance involved in the described testing.

    6. If a standalone (i.e., algorithm only without human-in-the-loop performance) was done

    This is not applicable. The device is an implantable dental restoration, not an algorithm. While CADCAM software is used in its design, the testing performed is for the physical product, not the standalone performance of the software as a diagnostic or AI tool. The document states: "Validation of the CARES Visual CAD software provides evidence that design parameters for the Straumann CARES Screw-Retained Bridges and Straumann CARES Dolder Bars have met their pre-determined acceptance criteria and that dental restorations meeting their design specifications can be manufactured by Straumann CAM milling devices." This refers to the software's ability to produce designs that meet specifications for manufacturing, not its "standalone performance" in an AI/ML context.

    7. The type of ground truth used

    The ground truth used for this submission is based on:

    • International Standards: ISO 22674 (Dentistry - Metallic materials for fixed and removable restorations and appliances) and ISO 9693 (Metal-ceramic dental restorative systems) for physical and mechanical requirements.
    • Biocompatibility Standards: Implicitly, standards related to biocompatibility testing for medical devices.
    • Established Material Science Metrics: Specific quantifiable parameters like density, proof strength, elongation, corrosion rates, and cytotoxicity.

    8. The sample size for the training set

    This is not applicable. There is no "training set" in the context of material and device performance testing for a traditional medical device like this, which is not an AI/ML product.

    9. How the ground truth for the training set was established

    This is not applicable for the same reasons as point 8.

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