K Number
K971911
Manufacturer
Date Cleared
1997-06-03

(36 days)

Product Code
Regulation Number
876.1620
Reference & Predicate Devices
N/A
Predicate For
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

The LuMax Cystometry Tube Set is intended to be used in the exact same manner as the previous tube sets manufactured by NASP and cleared by FDA under K911865/B. The intended use of these tube sets is to provide a conduit from a liquid resevoir to the infusion lumen of a bladder pressure catheter.
The LuMax Cystometry Tube Set is to be used to provide a conduit from a liguid reservoir to the infusion lumen of a bladder catheter whenever filling a bladder is required in conjunction with performing a Urodynamic Cystometry test.

Device Description

The LuMax Cystometry Tube Set consists of a vented spike with a drip chamber for connection to the liquid reservoir, usually a one to three liter saline or DI water bag, a roller clamp for regulating fluid flow rates, and a male luer lock connector for connecting to the filling lumen of the bladder catheter. It is assembled with polyurethane tubing giving it an overall length of 72 inches.

AI/ML Overview

The LuMax Cystometry Tube Set is a Class II medical device intended to provide a conduit from a liquid reservoir to the infusion lumen of a bladder pressure catheter. The device was found to be substantially equivalent to an existing administration tube set from North American Sterilization and Packaging Company (NASP) (K911865/B).

1. Table of Acceptance Criteria and Reported Device Performance

Test TypeAcceptance Criteria (Required Specifications)Reported Device Performance
Physical Bench Testing
Visual ExaminationVisual inspection for workmanship.All samples met required specifications.
Tensile Strength TestingRefer to Attachment H for specific specifications.All samples met required specifications.
Pressure Withstand TestingRefer to Attachment H for specific specifications.All samples met required specifications.
SterilizationSterility Assurance Level (SAL) of better than 10⁻⁶.Complete kill of Bacillus var niger spores, proving SAL > 10⁻⁶.
PackagingPackaging identical to predicate device's standards.Identical to MedAmicus Urodynamic Fiberoptic Pressure Catheter products (sealed Tyvek Pouch, carton for shipping).

2. Sample Sizes Used for the Test Set and Data Provenance

  • Physical Bench Testing: "Sample devices" were subjected to physical bench testing. The exact number of samples is not explicitly stated in the provided text, but it is implied that a sufficient number was tested to make a general statement about all samples meeting specifications.
  • Sterilization Validation: "Sample product" was used for sterilization validation. The exact number of samples is not explicitly stated.
  • Data Provenance: The data is retrospective, generated from in-house bench testing and sterilization validation performed by MedAmicus, Inc. The country of origin for the data is implicitly the United States, given the company's address and communication with the FDA.

3. Number of Experts Used to Establish Ground Truth for the Test Set and Qualifications of Those Experts

No external experts were explicitly mentioned as being used to establish a ground truth for the device's performance in the provided text. The "ground truth" for the physical and sterilization tests was based on established engineering specifications and validation methods (e.g., AAMI method for sterilization).

4. Adjudication Method for the Test Set

Not applicable. The tests performed were objective physical and sterilization validation tests against predefined specifications, not subjective assessments requiring adjudication by multiple readers or experts.

5. Multi-Reader Multi-Case (MRMC) Comparative Effectiveness Study

No multi-reader multi-case (MRMC) comparative effectiveness study was conducted or reported. This device is a passive conduit tube set, and its performance is not evaluated in terms of human reader improvement with or without AI assistance.

6. Standalone Performance Study (Algorithm Only Without Human-in-the-Loop Performance)

Yes, a standalone study was performed. The device performance (physical bench testing, sterilization, and packaging) was evaluated in an "algorithm-only" or "device-only" manner without human interaction influencing the core performance metrics being tested. The device itself was the subject of the performance tests.

7. Type of Ground Truth Used

  • Physical Bench Testing: Engineering specifications and material science standards (e.g., for tensile strength, pressure withstand) were used as the ground truth.
  • Sterilization: The AAMI method's criteria for a Sterility Assurance Level (SAL) of better than 10⁻⁶, demonstrated by a complete kill of 1 million spores of Bacillus var niger after a half-cycle, served as the ground truth.

8. Sample Size for the Training Set

Not applicable. This device is a passive medical device, not an AI/ML algorithm requiring a "training set."

9. How the Ground Truth for the Training Set Was Established

Not applicable. This device is a passive medical device, not an AI/ML algorithm requiring a "training set."

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JUN - 3 1997

PAGE I OF 3

510(k) Summary

LuMax Cystometry Tube Set

General Information

Classification Class II

Trade NameLuMax Cystometry Tube Set
SubmitterMedAmicus, Inc.15301 Highway 55 WestMinneapolis, MN 55447
ContactDennis S. MadisonVice President of Administration and regulatory Affairs(612) 559-2613

Predicate Devices

Administration tube set from North American Sterilization and Packaging Company (NASP).

Device Description Information

Intended Use

The LuMax Cystometry Tube Set is intended to be used in the exact same manner as the previous tube sets manufactured by NASP and cleared by FDA under K911865/B. The intended use of these tube sets is to provide a conduit from a liquid resevoir to the infusion lumen of a bladder pressure catheter.

Device Description

The LuMax Cystometry Tube Set consists of a vented spike with a drip chamber for connection to the liquid reservoir, usually a one to three liter saline or DI water bag, a roller clamp for regulating fluid flow rates, and a male luer lock connector for connecting to the filling lumen of the bladder catheter. It is assembled with polyurethane tubing giving it an overall length of 72 inches.

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The materials used in the manufacture of the tube set are used in similar tubing sets and in urologic catheters. The methods of packaging and sterilization are the same as MedAmicus uses in its Fiberoptic Catheter line.

PAGE ZOF 3

100 100 100 100 100 100

Device Performance / Product Testing

Sample devices will be subjected to physical bench testing. Tests will include visual examination for workmanship, tensile strength testing and pressure withstand testing. All samples will meet the required specifications. Test descriptions and specifications are contained in Attachment H.

Sterilization Information

The sterilization cycle for the LuMax Cystometry Tube Set will be identical to the cycle for the Urodynamic Fiberoptic Catheters.The ETO sterilization cycle for these products was validated using the AAMI method of three half cycles and one full cycle.

Validation tests were performed with spore strips (one million spores of Bacillus var niger) placed in sample product and sterilized at one half the regular cycle. The results showed a complete kill which proves a Sterility Assurance Level (SAL) of better than 10°. See Attachment D for further information.

Packaging

The packaging materials for the package are identical to the MedAmicus Urodynamic Fiberoptic Pressure Catheter products. The product is placed within a sealed Tyvek Pouch. The sterile product, with appropriated labeling, is then placed in a carton for shipping.

Substantial Equivalence

The LuMax Cystometry Tube Set is intended to provide a conduit from a saline or DI resevoir and the infusion lumen of a bladder pressure catheter. The basic design, methods of manufacturing, and materials used are identical to existing administration tube sets cleared by the FDA. Our application of this device is substantially equivalent to the aforementioned standard medical devices already approved for use. The clinical indications for use remain unchanged. MedAmicus believes the LuMax

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Cystometry Tube Set is substantially equivalent to currently marketed medical administration tube sets employing the same technology.

Conclusion

In conclusion, MedAmicus believes the LuMax Cystometry Tube Set is substantially equivalent to the predicate administration tube sets. The intended use, materials, sterilization, packaging, labeling, and method of operation and manufacturing methods are substantially equivalent.

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Image /page/3/Picture/0 description: The image shows the seal of the U.S. Department of Health & Human Services. The seal is circular and contains the words "DEPARTMENT OF HEALTH & HUMAN SERVICES. USA" around the perimeter. In the center of the seal is a stylized eagle with its wings spread.

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

JUN - 3 1997

Mr. Dennis S. Madison Vice President of Administration and Regulatory Affairs MedAmicus, Inc. 15301 Highway 55 West Plymouth, Minnesota 55447

Re: K971911

LuMax Cystometry Tube Set .... Dated: April 24, 1997 Received: April 28, 1997 Regulatory Class: II 21 CFR 876.1620/Procode: 78 FEN

Dear Mr. Madison:

We have reviewed your Section 510(k) notification of intent to market the device referenced above and we have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (Premarket Approval), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 895. A substantially equivalent determination assumes compliance with the Good Manufacturing Practice for Medical Devices: General (GMP) regulation (21 CFR Part 820) and that, through periodic GMP inspections, the Food and Drug Administration (FDA) will verify such assumptions. Failure to comply with the GMP regulation may result in regulatory action. In addition, FDA may publish further announcements concerning your device in the Federal Register. Please note: this response to your premarket notification submission does not affect any obligation you might have under sections 531 through 542 of the Act for devices under the Electronic Product Radiation Control provisions, or other Federal laws or regulations.

This letter will allow you to begin marketing your device as described in your 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801 and additionally 809.10 for in vitro diagnostic devices), please contact the Office of Compliance at (301) 594-4616. Additionally, for questions on the promotion and advertising of your device, please contact the Office of Compliance at (301) 594-4639. Also, please note the regulation entitled. "Misbranding by reference to premarket notification" (21 CFR 807.97). Other general information on your responsibilities under the Act may be obtained from the Division of Small Manufacturers Assistance at its toll-free number (800) 638-2041 or (301) 443-6597 or at its internet address "http://www.fda.gov/cdrh/dsmamain.html".

Sincerely yours,

William Yin, Ph.D.

Lillian Yin. Ph.D. Director, Division of Reproductive. Abdominal, Ear, Nose and Throat, and Radiological Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

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S10(k) Number (if known): K9719 ||

ADMINISTRATION TOBINE SET Device Name: Cystomersey

Indications For Use:

The LuMax Cystometry Tube Set is to be used to provide a conduit from a liguid reservoir to the infusion lumen of a bladder catheter whenever filling a bladder is required in conjunction with performing a Urodynamic Cystometry test .

(PLEASE DO NOT WRITE BELOW THIS LINE - CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Peter R. Sutherg
(Division Sign-Off)

Division of Reproductive, Abdominal, ENT, and Radiological Devices 510(k) Number 719

Prescription Use (Per 21 CFR. 801.109)

OR

Over-The-Counter Use

(Optional Format 1-2-96)

§ 876.1620 Urodynamics measurement system.

(a)
Identification. A urodynamics measurement system is a device used to measure volume and pressure in the urinary bladder when it is filled through a catheter with carbon dioxide or water. The device controls the supply of carbon dioxide or water and may also record the electrical activity of the muscles associated with urination. The device system may include transducers, electronic signal conditioning and display equipment, a catheter withdrawal device to enable a urethral pressure profile to be obtained, and special catheters for urethral profilometry and electrodes for electromyography. This generic type of device includes the cystometric gas (carbon dioxide) device, the cystometric hydrualic device, and the electrical recording cystometer, but excludes any device that uses air to fill the bladder.(b)
Classification. Class II (special controls). The device is exempt from the premarket notification procedures in subpart E of part 807 of this chapter subject to § 876.9.