K Number
K971345
Device Name
CHOL OR CHOLESTEROL
Date Cleared
1997-05-29

(49 days)

Product Code
Regulation Number
862.1175
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
Cholesterol Reagent is intended for the quantitative determination of serum total cholesterol using Beckman SYNCHRON CX Systems. The results are used in the diagnosis and treatment of disorders involving excess cholesterol in the blood as well as lipid and lipoprotein metabolism disorders.
Device Description
Not Found
More Information

Not Found

Not Found

No
The summary describes a reagent for a laboratory analyzer and does not mention any AI or ML components or functionalities.

No.
Explanation: The device is a diagnostic reagent for measuring cholesterol levels, which aids in diagnosis and treatment, but it does not directly treat a disorder or condition itself.

Yes
The "Intended Use / Indications for Use" section states: "The results are used in the diagnosis and treatment of disorders involving excess cholesterol in the blood as well as lipid and lipoprotein metabolism disorders." This indicates its use in diagnosing conditions.

No

The device description is not found, but the intended use clearly describes a "Cholesterol Reagent" for use with a "Beckman SYNCHRON CX System," which are hardware components.

Yes, this device is an IVD (In Vitro Diagnostic).

Here's why:

  • Intended Use: The intended use explicitly states it's for the "quantitative determination of serum total cholesterol." This involves testing a biological sample (serum) outside of the body.
  • Purpose: The results are used in the "diagnosis and treatment of disorders involving excess cholesterol in the blood as well as lipid and lipoprotein metabolism disorders." This directly relates to medical diagnosis and treatment, which is a key characteristic of IVDs.
  • Device Type: It's a "Cholesterol Reagent," which is a substance used in a laboratory test to detect or measure a specific substance in a biological sample. Reagents used for diagnostic purposes are considered IVDs.
  • System Used: It's used with "Beckman SYNCHRON CX Systems," which are laboratory analyzers designed for performing in vitro diagnostic tests.

All these points align with the definition of an In Vitro Diagnostic device.

N/A

Intended Use / Indications for Use

Cholesterol Reagent is intended for the quantitative determination of serum total cholesterol using CX Systems. Beckman SYNCHRON used in the diagnosis and treatment The results are of disorders involving excess cholesterol in the lipid and lipoprotein metabolism blood as well as disorders.

Product codes

CHH

Device Description

Not Found

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

Not Found

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Not Found

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies (study type, sample size, AUC, MRMC, standalone performance, key results)

Not Found

Key Metrics (Sensitivity, Specificity, PPV, NPV, etc.)

Not Found

Predicate Device(s)

Not Found

Reference Device(s)

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information

Not Found

§ 862.1175 Cholesterol (total) test system.

(a)
Identification. A cholesterol (total) test system is a device intended to measure cholesterol in plasma and serum. Cholesterol measurements are used in the diagnosis and treatment of disorders involving excess cholesterol in the blood and lipid and lipoprotein metabolism disorders.(b)
Classification. Class I (general controls). The device is exempt from the premarket notification procedures in subpart E of part 807 of this chapter subject to § 862.9.

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Image /page/0/Picture/1 description: The image shows the logo for the U.S. Department of Health & Human Services. The logo consists of a stylized eagle with three stripes extending from its body, representing the department's mission to protect the health of all Americans and provide essential human services. The text "DEPARTMENT OF HEALTH & HUMAN SERVICES • USA" is arranged in a circular fashion around the eagle symbol.

Food and Drug Administration 2098 Gaither Road Rockville MD 20850

MAY 2 9 1997

Cynthia Shugart President Carolina Liquid Chemistries Corporation 451 West Lambert Road, Suite 207 Brea, California 92821

Re: K971345 Cholesterol Reagent Requlatory Class: I Product Code: СНН April 8, 1997 Dated: Received: April 10, 1997

Dear Ms. Shugart:

We have reviewed your Section 510(k) notification of intent to market the device referenced above and we have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act). You may, therefore, market the device, subject to the general controls provisions The general controls provisions of the Act of the Act. include requirements for annual registration, listing of devices, qood manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (Premarket Approval), it may be subject to such additional controls. Existing major requlations affecting your device can be found in the Code of Federal Requlations, Title 21, Parts 800 to 895. A substantially equivalent determination assumes compliance with the Good Manufacturing Practice for Medical Devices: General (GMP) requlation (21 CFR Part 820) and that, through periodic GMP inspections, the Food and Drug Administration (FDA) will verify such assumptions. Failure to comply with the GMP requlation may result in regulatory action. In addition, FDA may publish further announcements concerning your device in the Federal Reqister. Please note: this response to your premarket notification submission does not affect any obligation you might have under sections 531 through 542 of the Act for devices under the Electronic Product Radiation Control provisions, or other Federal laws or regulations.

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All Property of the Property

Under the Clinical Laboratory Improvement Amendments of 1988 (CLIA-88), this device may require a CLIA complexity categorization. To determine if it does, you should contact the Centers for Disease Control and Prevention (CDC) at (770) 488-7655.

This letter will allow you to begin marketing your device as described in your 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801 and additionally 809.10 for in vitro diagnostic devices), please contact the Office of Compliance at (301) 594-4588. Additionally, for questions on the promotion and advertising of your device, please contact the Office of Compliance at (301) 594-4639. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21 CFR 807.97). Other general information on your responsibilities under the Act may be obtained from the Division of Small Manufacturers Assistance at its toll-free number (800) 638-2041 or (301) 443-6597 or at its internet address "http://www.fda.gov/cdrh/dsmamain.html".

Sincerely yours,
Steven Litman

Steven I. Gutman, M.D., M.B.A. Director Division of Clinical Laboratory Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

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Page_ 3 of 36

510(k) Number (if known): _

Device Name: Cholesterol Reagent

Indications For Use:

Cholesterol Reagent is intended for the quantitative determination of serum total cholesterol using CX Systems. Beckman SYNCHRON

used in the diagnosis and treatment The results are of disorders involving excess cholesterol in the lipid and lipoprotein metabolism blood as well as disorders.

(PLEASE DO NOT WAITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE IF NEEDED!

Concurrence of CDRH, Office of Device Evaluation (ODE)

510(k) Number

(Division Sign-Off)
Division of Clinical Laboratory Devices
15971345

Prescription Use
(Per 21 CFR 801.109)

Over - The - Counter Use_

(Optional Format 1-2-96)

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OR