K Number
K210253
Date Cleared
2021-11-05

(280 days)

Product Code
Regulation Number
880.6250
Reference & Predicate Devices
Predicate For
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

A powder-free patient examination glove is a disposable device intended for medical purposes that is worn on the examiner's hand or finger to prevent contamination between patient and examiner

Device Description

Latex Examination Powder Free Gloves are manufactured to meet all the current specifications listed under the ASTM Specification D3578 - 19, Standard Specification for Rubber Examination Gloves. They are made from Natural Rubber Latex. These gloves are natural in color is added) and are powder free.

AI/ML Overview

Here's a breakdown of the acceptance criteria and study information based on the provided document:

1. Table of Acceptance Criteria and Reported Device Performance

Test MethodStandardPurpose of TestingAcceptance CriteriaReported Device Performance
DimensionASTM D3578-19LengthMin 230 mm for all sizesSmall: 240 mm, Medium: 240 mm, Large: 240 mm, Extra Large: 241 mm (All Pass)
WidthSmall: 80 ± 10 mm, Medium: 95 ± 10 mm, Large: 111 ± 10 mm, Extra Large: 120 ± 10 mmSmall: 85 mm, Medium: 93 mm, Large: 105 mm, Extra Large: 115 mm (All Pass)
Thickness (Palm)0.08 mm min for all sizesSmall: 0.09 mm, Medium: 0.09 mm, Large: 0.10 mm, Extra Large: 0.09 mm (All Pass)
Thickness (Finger)0.08 mm min for all sizesSmall: 0.12 mm, Medium: 0.12 mm, Large: 0.13 mm, Extra Large: 0.12 mm (All Pass)
Physical PropertiesASTM D3578-19Tensile Strength (Before Aging)18 MPa Minimal for all sizesSmall: 18.04 MPa, Medium: 19.13 MPa, Large: 18.26 MPa, Extra Large: 18.64 MPa (All Pass)
Tensile Strength (After Aging)14 MPa Minimal for all sizesSmall: 15.02 MPa, Medium: 18.12 MPa, Large: 16.01 MPa, Extra Large: 15.06 MPa (All Pass)
Ultimate Elongation (Before Aging)650% Min for all sizesSmall: 651%, Medium: 654%, Large: 650%, Extra Large: 650% (All Pass)
Ultimate Elongation (After Aging)500% Min for all sizesSmall: 501%, Medium: 601%, Large: 501%, Extra Large: 502% (All Pass)
Watertight TestASTM D5151-19Detection of HolesSample size: 200 pcs, Inspection level: GI, AQL 1.5, Acceptance Number 7, Rejection Number 8Small: 0, Medium: 0, Large: 0, Extra Large: 0 (All Pass)
Residual PowderASTM D6124-06 (Reapproved 2017)Residual powder in gloves2 mg per glove or lessSmall: 0.62 mg/glove, Medium: 0.46 mg/glove, Large: 0.61 mg/glove, Extra Large: 0.61 mg/glove (All Pass)
Protein ContentASTM D5712-15Extractable protein in natural rubberLess than 200 µg/dm²Small: 124.36 µg/dm², Medium: 140.78 µg/dm², Large: 134.26 µg/dm², Extra Large: 159.46 µg/dm² (All Pass)
BiocompatibilityISO 10993-10Primary Skin IrritationNot a primary skin irritantNot a primary skin irritant under the conditions of the study (Pass)
Dermal SensitizationNot a contact sensitizerNot a contact sensitizer under the conditions of the study (Pass)
ISO 10993-5In vitro cytotoxicityNo data available for predicate (Tested for subject device)Cytotoxic for undiluted and 1:2 dilutions, non-cytotoxic for 1:4, 1:8, 1:16, 1:32 dilutions for subject device (Different from predicate, but indicates testing)
ISO 10993-11Acute Systemic ToxicityNo data available for predicate (Tested for subject device)Did not induce any systemic toxicity for subject device (Different from predicate, but indicates testing)

2. Sample Size Used for the Test Set and Data Provenance

  • Dimension Tests: While specific sample sizes for each dimension measurement aren't individually listed, the watertight test indicates a sample size of 200 pieces for that particular test. For residual powder, the sample size was 5 pieces. For protein content, the sample size was 3 pieces.
  • Data Provenance: The document does not explicitly state the country of origin or whether the data is retrospective or prospective. Given that the manufacturer is Bestsafe Glove Co., LTD. based in Thailand, it is highly likely that the testing was conducted in Thailand or by laboratories compliant with international standards on behalf of the manufacturer. The tests are presented as part of a 510(k) submission, typically involving tests specifically conducted for the device seeking clearance.

3. Number of Experts Used to Establish the Ground Truth for the Test Set and Their Qualifications

  • This information is not applicable as the document describes performance testing for medical gloves against established ASTM and ISO standards, not a diagnostic or AI-driven device requiring human expert ground truth for image interpretation or similar tasks. The "ground truth" here is defined by the objective measurement criteria within the specified standards.

4. Adjudication Method for the Test Set

  • This information is not applicable for the same reasons as point 3. The testing involves objective measurements against established numerical and qualitative criteria defined by the standards.

5. If a Multi-Reader Multi-Case (MRMC) Comparative Effectiveness Study Was Done, If So, What Was the Effect Size of How Much Human Readers Improve with AI vs. Without AI Assistance

  • This information is not applicable. The device is a physical medical glove, not an AI-assisted diagnostic or imaging device. Therefore, no MRMC study or AI assistance comparison was performed.

6. If a Standalone (i.e., algorithm only without human-in-the-loop performance) Was Done

  • This information is not applicable. The device is a physical medical glove, not a software or AI-based device.

7. The Type of Ground Truth Used

  • The ground truth for the performance of the gloves is established through objective measurements against predefined criteria and thresholds set by international standards for medical gloves, specifically:
    • ASTM D3578-19 (Standard Specification for Rubber Examination Gloves)
    • ASTM D5151-19 (Standard Test Method for Detection of Holes in Medical Gloves)
    • ASTM D6124-06 (Reapproved 2017) (Standard Test Method for Residual Powder on Medical Gloves)
    • ASTM D5712-15 (Standard Test Method for Analysis of Aqueous Extractable Protein in Natural Rubber)
    • ISO 10993-10 (Biological evaluation of medical devices – Part 10: Tests for irritation and skin sensitization)
    • ISO 10993-5 (Biological evaluation of medical devices – Part 5: Tests for in vitro cytotoxicity)
    • ISO 10993-11 (Biological evaluation of medical devices – Part 11: Tests for systemic toxicity)

8. The Sample Size for the Training Set

  • This information is not applicable. The device is a physical product, not a machine learning model, so there is no "training set."

9. How the Ground Truth for the Training Set Was Established

  • This information is not applicable for the same reason as point 8.

{0}------------------------------------------------

Image /page/0/Picture/0 description: The image shows the logo of the U.S. Food and Drug Administration (FDA). On the left is the Department of Health & Human Services logo. To the right of that is the FDA logo, with the letters "FDA" in a blue square. Next to that is the text "U.S. FOOD & DRUG ADMINISTRATION" in blue.

November 5, 2021

Bestsafe Glove CO., LTD. Piyawat Chirasakulkarun Chief Executive Officer 52/43 Wat Khot Hin-Khao Phai Road, T. Tubma Muang Rayong, Rayong 21000 Thailand

Re: K210253

Trade/Device Name: Best Glove-Latex Powder Free Examination Glove Regulation Number: 21 CFR 880.6250 Regulation Name: Non-powdered patient examination glove Regulatory Class: Class I, reserved Product Code: LYY Dated: May 25, 2021 Received: August 30, 2021

Dear Piyawat Chirasakulkarun:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. Although this letter refers to your product as a device, please be aware that some cleared products may instead be combination products. The 510(k) Premarket Notification Database located at https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpmn/pmn.cfm identifies combination product submissions. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you, however, that device labeling must be truthful and not misleading.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal

{1}------------------------------------------------

statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); medical device reporting of medical device-related adverse events) (21 CFR 803) for devices or postmarketing safety reporting (21 CFR 4, Subpart B) for combination products (see https://www.fda.gov/combination-products/guidance-regulatory-information/postmarketing-safety-reportingcombination-products); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820) for devices or current good manufacturing practices (21 CFR 4, Subpart A) for combination products; and, if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21 CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to https://www.fda.gov/medical-device-safety/medical-device-reportingmdr-how-report-medical-device-problems.

For comprehensive regulatory information about medical devices and radiation-emitting products, including information about labeling regulations, please see Device Advice (https://www.fda.gov/medicaldevices/device-advice-comprehensive-regulatory-assistance) and CDRH Learn (https://www.fda.gov/training-and-continuing-education/cdrh-learn). Additionally, you may contact the Division of Industry and Consumer Education (DICE) to ask a question about a specific regulatory topic. See the DICE website (https://www.fda.gov/medical-device-advice-comprehensive-regulatoryassistance/contact-us-division-industry-and-consumer-education-dice) for more information or contact DICE by email (DICE@fda.hhs.gov) or phone (1-800-638-2041 or 301-796-7100).

Sincerely,

For Clarence W. Murray, III, Ph.D. Assistant Director DHT4B: Division of Infection Control and Plastic Surgery Devices OHT4: Office of Surgical and Infection Control Devices Office of Product Evaluation and Quality Center for Devices and Radiological Health

Enclosure

{2}------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration

Indications for Use

Form Approved: OMB No. 0910-0120 Expiration Date: January 31, 2017 See PRA Statement below.

510(k) Number (if known) K210253

Device Name

BEST GLOVE -LATEX POWDER FREE EXAMINATION GLOVE

Indications for Use (Describe)

A powder-free patient examination glove is a disposable device intended for medical purposes that is worn on the examiner's hand or finger to prevent contamination between patient and examiner

Type of Use (Select one or both, as applicable)

Prescription Use (Part 21 CFR 801 Subpart D)

× Over-The-Counter Use (21 CFR 801 Subpart C)

CONTINUE ON A SEPARATE PAGE IF NEEDED.

This section applies only to requirements of the Paperwork Reduction Act of 1995.

DO NOT SEND YOUR COMPLETED FORM TO THE PRA STAFF EMAIL ADDRESS BELOW.

The burden time for this collection of information is estimated to average 79 hours per response, including the time to review instructions, search existing data sources, gather and maintain the data needed and complete and review the collection of information. Send comments regarding this burden estimate or any other aspect of this information collection, including suggestions for reducing this burden, to:

Department of Health and Human Services Food and Drug Administration Office of Chief Information Officer Paperwork Reduction Act (PRA) Staff PRA Staff@fda.hhs.gov

"An agency may not conduct or sponsor, and a person is not required to respond to, a collection of information unless it displays a currently valid OMB number.

{3}------------------------------------------------

Image /page/3/Picture/0 description: The image shows the logo for BESTSAFE GLOVE CO., LTD. The logo features a blue hand on the left side, followed by the word "BESTSAFE" in blue, with a plus sign in the middle of the word. Below the word "BESTSAFE" is the company name "BESTSAFE GLOVE CO., LTD" in smaller blue letters. There is a registered trademark symbol in the upper right corner of the logo.

52/43 WATKODHIN-KAOPHAI RD. T.TUBMA, A.MUANG, RAYONG, RAYONG. THAILAND 21000 TAX ID:0215563006105 TEL OFFICE : 038-949877-79 FAX : (+66)038-694493, 038-949899 TEL H/P : +66-0-86-3173770 , +66-0-81-4022099 ,+66-0-62-325-6558 EMAIL : SALES@BESTSAFE.CO.TH WEBSITE : WWW.BESTSAFE.CO.TH I WWW.BESTSAFEGLOVE.COM

510(k) SUMMARY K210253 Latex Powder Free Examination Glove

1.0 Applicant Information

Applicant:BESTSAFE GLOVE CO., LTD
Address52/43 Watkodhin-Kaophai Rd. T. Tubma,A. Muang Rayong Rayong. THAILAND 21000
Phone Number:+66 (038)-949880
Fax Number:+66 (038)-949850
Name of Contact Person:Piyawat Chirasakulkarun
Contact Number:+66 81 4022099
Contact Email:sales@bestsafe.co.th
Preparation date:September 6, 2021
2.0Device Identification:
Trade/Proprietary Name(s):BEST GLOVE -LATEX POWDER FREE EXAMINATION GLOVE
Common Name:Latex Powder Free Examination Gloves
Classification Name:Patient Examination Gloves
510(k):K210253
Device Class:I
Product Code:LYY
Registration Number21 CFR 880.6250
Review PanelGeneral Hospital
3.0Predicate Device
Device Name:MPXX™ Powder Free Natural Rubber Latex Examination Gloves
Manufacturer:Total Glove Company Sdn. Bhd.
510(k):K110250
Device Class:I
Product Code:LYY

{4}------------------------------------------------

Image /page/4/Picture/0 description: The image shows the logo for BESTSAFE GLOVE CO., LTD. The logo features a blue hand on the left side, followed by the word "BESTSAFE" in blue with a plus sign in the middle. Below "BESTSAFE" is the text "BESTSAFE GLOVE CO., LTD" in a smaller font size. There is a registered trademark symbol in the upper right corner of the logo.

52/43 WATKODHIN-KAOPHAI RD. T.TUBMA, AMUANG, RAYONG, RAYONG. THAILAND 21000 TEL OFFICE : 038-949877-79 FAX : (+66)038-694493, 038-949899 TAX ID:0215563006105 TEL H/P : +66-0-86-3173770 , +66-0-81-4022099 ,+66-0-62-325-6558 EMAIL : SALES@BESTSAFE.CO.TH WEBSITE : WWW.BESTSAFE.CO.TH I WWW.BESTSAFEGLOVE.COM

4.0 Description of the Device:

Latex Examination Powder Free Gloves are manufactured to meet all the current specifications listed under the ASTM Specification D3578 - 19, Standard Specification for Rubber Examination Gloves. They are made from Natural Rubber Latex. These gloves are natural in color is added) and are powder free.

5.0 Indication for Use of the Device:

A powder-free patient examination glove is a disposable device intended for medical purposes that is worn on the examiner's hand or finger to prevent contamination between patient and examiner

6.0 Comparison of Technological characteristics between predicate and subject devices

CharacteristicsReferences/StandardsDevice performanceComparison
PredicateCurrent
510(k) Number-K110250K210253---
Manufacturer(s)-Total Glove Company Sdn.Bhd.BESTSAFE GLOVE CO.,LTD---
Name of device-MPXX TM Powder Free NaturalRubber Latex ExaminationGlovesBEST GLOVE -LATEXPOWDER FREEEXAMINATION GLOVE---
Indication for UseMedical GlovesGuidance Manual,Issued on January 22,2008MPXX TM Powder Free NaturalRubber Latex ExaminationGloves are single use deviceintended for medical purposesthat is worn on the hand ofhealthcare and similarpersonnel to preventcontamination betweenhealthcare and the patient.A powder-free patientExamination Glove is adisposable device intendedfor medical purposes that isworn on the examiner's handor finger to preventcontamination betweenpatient and examinerSame
MaterialASTM D3578-19Natural Rubber LatexNatural Rubber LatexIdentical
ColorNatural ColoNatural ColoSame
SizeMedical GloveGuidance Manual-Labeling- Issued onJanuary 22, 2008Extra SmallSmallMediumLargeExtra LargeSmallMediumLargeExtra LargeDifferent
CharacteristicsReferences/StandardsDevice performanceComparison
Single UseMedical GlovesGuidance Manual -Issued on January 22,2008Single useSingle useSame
Sterile/Non-sterile-Non-sterileNon-sterileSame
DimensionASTM D3578-19Length230 mm minimumLength230 mm minSimilar
SizeActual value
Small240
Medium240
Large240
Extra Large241
WidthMedium: 95 mm ± 10 mm(for Medium size)Different
SizeActual value
Small85
Medium93
Large105
Extra Large115
ThicknessASTM D3578-19Finger = 0.08 mm. minPalm = 0.08 mm. MinFinger = 0.08 mm. minPalm = 0.08 mm. MinSimilar
SizePalm(Actual value)Finger(Actual value)
Small0.090.12
Medium0.090.12
Large0.100.13
Extra Large0.090.12

{5}------------------------------------------------

Image /page/5/Picture/0 description: The image shows the logo for BESTSAFE. On the left is a blue hand. To the right of the hand is the word "BESTSAFE" in blue, with a plus sign in the upper left corner of the word. Below the word "BESTSAFE" is the text "BESTSAFE GLOVE CO.,LTD" in a smaller font.

52/43 WATKODHIN-KAOPHAI RD. T.TUBMA, A.MUANG, RAYONG, RAYONG. THAILAND 21000 TEL OFFICE : 038-949877-79 FAX : (+66)038-694493, 038-949899 TAX ID:0215563006105 TEL H/P : +66-0-86-3173770 , +66-0-81-4022099 ,+66-0-62-325-6558

WEBSITE : WWW.BESTSAFE.CO.TH I WWW.BESTSAFEGLOVE.COM EMAIL : SALES@BESTSAFE.CO.TH

{6}------------------------------------------------

Image /page/6/Picture/0 description: The image shows the logo for BESTSAFE GLOVE CO., LTD. The logo features a blue hand on the left side. To the right of the hand is the word "BESTSAFE" in blue, with a plus sign incorporated into the "B". Below "BESTSAFE" is the text "BESTSAFE GLOVE CO.,LTD" also in blue.

52/43 WATKODHIN-KAOPHAI RD. T.TUBMA, A.MUANG, RAYONG, RAYONG. THAILAND 21000 TEL OFFICE : 038-949877-79 FAX : (+66)038-694493, 038-949899 TAX ID:0215563006105 TEL H/P : +66-0-86-3173770 , +66-0-81-4022099 ,+66-0-62-325-6558 WEBSITE : WWW.BESTSAFE.CO.TH I WWW.BESTSAFEGLOVE.COM EMAIL : SALES@BESTSAFE.CO.TH

CharacteristicsReferences/StandardsDevice performanceComparison
PredicateCurrent
Physical PropertiesASTM D3578-19Before AgingTensile Strength18 MPa minAfter AgingTensile Strength14 MPa minBefore AgingTensile Strength (18 MPa min) Size Actual value Small 18.04 Medium 19.13 Large 18.26 Extra Large 18.64Similar
CharacteristicsReferences/StandardsDevice performanceComparison
PredicateCurrent
Water Tight Test(1000 ml)ASTM D5151 – 19Pass AQL 1.5After AgingTensile Strength (14 MPa min) Size Actual value Small 15.02 Medium 18.12 Large 16.01 Extra Large 15.06Pass AQL 1.5SameSimilar
Powder ResidualASTM D6124-06(Reapproved 2017)Meet $≤$ 2.0 mg/glove$≤$ 2.0 mg/gloveSimilar
Size Residual powder content (mg/glove) Small 0.62 Medium 0.46 Large 0.61 Extra Large 0.61
Before AgingUltimate Elongation650% minAfter AgingUltimate Elongation500% min (after aging)Before AgingUltimate Elongation : 650% min Size Actual value Small 651 Medium 654 Large 650 Extra Large 650Similar
BiocompatibilityPrimary Skin Irritation -ISO 10993-10 ThirdEdition 2010-08-01Not a primary skin irritant under the conditions of the studyNot a primary skin irritant under the conditions of the studySame
Dermal Sensitization -ISO 10993-10 ThirdEdition 2010-08-01Not a contact sensitizer under the conditions of the studyNot a contact sensitizer under the conditions of the studySame
In vitro cytotoxicityISO10993-5 :2009(E)No data is availableUnder the conditions of the study cytotoxic for undiluted (neat) and 1:2 dilutions but noncytotoxic for 1:4, 1:8, 1:16 and 1:32 dilutions. Moreover, under the conditions of the study, non acute systemic toxic.Different
Acute Systemic ToxicityISO10993-11:2017(E)No data is availableUnder the conditions of the study, did not induce any systemic toxicity.Different
After AgingUltimate Elongation : 500% min Size Actual value Small 501 Medium 601 Large 501 Extra Large 502Similar

{7}------------------------------------------------

Image /page/7/Picture/0 description: The image contains the logo for BESTSAFE GLOVE CO., LTD. The logo features a blue hand on the left side, followed by the word "BESTSAFE" in blue with a white cross in the middle of the "B". Below "BESTSAFE" is the text "BESTSAFE GLOVE CO., LTD" in a smaller font size. There is a registered trademark symbol in the upper right corner of the logo.

52/43 WATKODHIN-KAOPHAI RD. T.TUBMA, A.MUANG, RAYONG, RAYONG. THAILAND 21000 TAX ID:0215563006105 TEL OFFICE : 038-949877-79 FAX : (+66)038-694493, 038-949899 TEL H/P : +66-0-86-3173770 , +66-0-81-4022099 ,+66-0-62-325-6558

WEBSITE : WWW.BESTSAFE.CO.TH I WWW.BESTSAFEGLOVE.COM EMAIL : SALES@BESTSAFE.CO.TH

{8}------------------------------------------------

Image /page/8/Picture/0 description: The image shows the logo for BESTSAFE GLOVE CO., LTD. The logo features a blue hand on the left side, followed by the word "BESTSAFE" in blue, with a plus sign in the middle of the word. Below "BESTSAFE" is the text "BESTSAFE GLOVE CO.,LTD" also in blue. There is a registered trademark symbol in the upper right corner of the logo.

52/43 WATKODHIN-KAOPHAI RD. T.TUBMA, A.MUANG, RAYONG, RAYONG. THAILAND 21000

TAX ID:0215563006105 TEL OFFICE : 038-949877-79 FAX : (+66)038-694493, 038-949899 TEL H/P : +66-0-86-3173770 , +66-0-81-4022099 ,+66-0-62-325-6558

WEBSITE : WWW.BESTSAFE.CO.TH | WWW.BESTSAFEGLOVE.COM EMAIL : SALES@BESTSAFE.CO.TH

7.0 Summary of Non-clinical performance Tests

Test MethodStandardPurpose of testingAcceptance CriteriaResultStatus
DimensionASTM D3578-19Standard Specification for RubberExamination GlovesTo determine the lengthof the glovesMin 230 mm for all sizesSmall: 240 mmMedium: 240 mmLarge: 240 mmExtra Large: 241 mmPass
ASTM D3578-19Standard Specification for RubberExamination GlovesTo determine the widthof the glovesSmall: 80 ± 10 mmMedium: 95±10mmLarge: 111± 10 mmExtra Large: 120 ± 10 mmSmall: 85 mmMedium: 93 mmLarge: 105 mmExtra Large: 115 mmPass
ASTM D3578-19Standard Specification for RubberExamination GlovesTo determine thethickness of the glovesPalm 0.08 mm minFinger 0.08 mm min for all sizesSmall: Palm 0.09 mm, Finger: 0.12 mmMedium: Palm: 0.09 mm, Finger: 0.12 mmLarge: Palm 0.10 mm, Finger: 0.13 mmExtra Large: Palm 0.09 mm, Finger: 0.12 mmPass
PhysicalPropertiesASTM D3578-19Standard Specification for RubberExamination GlovesTo Determine thephysical properties-Tensile strengthBefore AgeingTensile Strength 18MpaMinimal for all sizesAfter Ageing TensileStrength 14MpaMinimal for all sizesBefore AgeingSmall: 18.04 MPaMedium: 19.13 MPaLarge: 18.26 MPaExtra Large: 18.64 MPaAfter ageing:Small: 15.02 MPaMedium: 18.12 MPaLarge: 16.01 MPaExtra Large: 15.06 MPaPass

{9}------------------------------------------------

Image /page/9/Picture/0 description: The image contains the logo for BESTSAFE GLOVE CO., LTD. The logo features a blue hand on the left side, followed by the word "BESTSAFE" in large, bold, blue letters. Below "BESTSAFE" is the text "BESTSAFE GLOVE CO.,LTD" in smaller, blue letters. There is a registered trademark symbol in the upper right corner of the logo.

52/43 WATKODHIN-KAOPHAI RD. T.TUBMA, A.MUANG, RAYONG, THAILAND 21000

TEL OFFICE : 038-949877-79 FAX : (+66)038-694493, 038-949899 TEL H/P : +66-0-86-3173770 , +66-0-81-4022099 ,+66-0-62-325-6558 TAX ID:0215563006105

WEBSITE : WWW.BESTSAFE.CO.TH | WWW.BESTSAFEGLOVE.COM EMAIL : SALES@BESTSAFE.CO.TH

Test MethodStandardPurpose of testingAcceptance CriteriaResultStatus
PhysicalPropertiesASTM D3578-19Standard Specification for RubberExamination GlovesTo Determine thephysical properties-Ultimate ElongationBefore AgeingUltimate Elongation650% Min for all sizesAfter Ageing UltimateElongation 500% Minfor all sizesBefore AgeingSmall: 651%Medium: 654 %Large:650%Extra Large:650%After ageing:Small:501%Medium: 601%Large:501%Extra Large:502%Pass
Watertight testASTM D5151-19Standard Test Method for Detectionof Holes in MedicalGlovesTo determine the holes inthe glovesSample size: 200 pcsInspection level : GlAQL 1.5Acceptance Number 7Rejection Number 8The batch size for this sampling is 35,001-150,000. Hence, according to the singlesampling plan GI, the sample to be drawnis under code L equivalent to 200 pcs withaccept 7 and reject 8 to be accept underAQL 1.5.Small: 0 (Zero)Medium: 0 (Zero)Large:0 (Zero)Extra Large:0 (Zero)Pass
ResidualpowderASTM D6124-06 (Reapproved 2017)Standard Test Method for ResidualPowder on Medical GlovesTo determine the residualpowder in the gloves2 mg per glove or lessSample size : 5 pcsRequirement: 2 mg per glove or lessResultSmall:0.62 mg/gloveMedium: 0.46 mg/gloveLarge: 0.61 mg/gloveExtra Large:0.61 mg/glovePass

{10}------------------------------------------------

Image /page/10/Picture/0 description: The image shows the logo for BESTSAFE GLOVE CO., LTD. The logo features a blue hand on the left, followed by the word "BESTSAFE" in blue, with a plus sign in the middle of the word. Below "BESTSAFE" is the text "BESTSAFE GLOVE CO., LTD" in a smaller font, also in blue. There is a registered trademark symbol in the upper right corner of the logo.

52/43 WATKODHIN-KAOPHAI RD. T.TUBMA, AMUANG, RAYONG, RAYONG. THAILAND 21000

TEL OFFICE : 038-949877-79 FAX : (+66)038-694493, 038-949899 TAX ID : 0215563006105 TEL H/P : +66-0-86-3173770 , +66-0-81-4022099 ,+66-0-62-325-6558 EMAIL : SALES@BESTSAFE.CO.TH WEBSITE : WWW.BESTSAFE.CO.TH I WWW.BESTSAFEGLOVE.COM

Status Test Method Standard Acceptance Criteria Purpose of testing Result Protein content ASTM D5712 - 15, Standard Test Less than 200 µg/dm² Pass To determine the Sample size : 3 pcs extractable protein in Method for Analysis of Aqueous Requirement: Less than 200 µg/dm2 Extractable Protein in Natural the gloves Result Small:124.36 ug /dm2 Rubber. Medium: 140.78 µg /dm² Large: 134.26 µg /dm² Extra 159.46 µg /dm²

The performance test data of the non-clinical tests meet following standards:

ASTM D 3578 – 19 Standard Specification for Rubber Examination Gloves

ASTM D 5151-19: Standard Test Method for Detection of Holes in Medical Gloves

ASTM D6124-06 (Reapproved 2017) Standard Test Method for Residual Powder on Medical Gloves

ASTM D5712 - 15, Standard Test Method for Analysis of Aqueous Extractable Protein in Natural Rubber.

{11}------------------------------------------------

Image /page/11/Picture/0 description: The image shows the logo for BESTSAFE GLOVE CO., LTD. The logo features a blue hand on the left side, followed by the word "BESTSAFE" in blue, with a plus sign in the middle of the word. Below "BESTSAFE" is the text "BESTSAFE GLOVE CO., LTD" in a smaller font size.

BESTSAFE GLOVE CO.,LTD. | บริษัท เบสท์เซฟ โกลฟ จำกัด 52/43 WATKODHIN-KAOPHAI RD. T.TUBMA, AMUANG, RAYONG, RAYONG. THAILAND 21000 TEL OFFICE : 038-949877-79 FAX : (+66)038-694493, 038-949899 TAX ID:0215563006105 TEL H/P : +66-0-86-3173770 , +66-0-81-4022099 ,+66-0-62-325-6558 EMAIL : SALES@BESTSAFE.CO.TH WEBSITE : WWW.BESTSAFE.CO.TH I WWW.BESTSAFEGLOVE.COM

8.0 Summary of Clinical Performance Tests:

Not Applicable

9.0 Conclusion:

The conclusion drawn from the non-clinical tests demonstrates that the subject device Latex Examination Powder Free Gloves is as safe, as effective, and performs as well as or better than the legally marketed predicate device K110250

--END--

§ 880.6250 Non-powdered patient examination glove.

(a)
Identification. A non-powdered patient examination glove is a disposable device intended for medical purposes that is worn on the examiner's hand or finger to prevent contamination between patient and examiner. A non-powdered patient examination glove does not incorporate powder for purposes other than manufacturing. The final finished glove includes only residual powder from manufacturing.(b)
Classification. Class I (general controls). The device, when it is a finger cot, is exempt from the premarket notification procedures in subpart E of part 807 of this chapter subject to the limitations in § 880.9.