K Number
K160326
Date Cleared
2016-02-23

(18 days)

Product Code
Regulation Number
892.2050
Reference & Predicate Devices
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

5MP Monochrome LCD Monitor MS55i2 (ML21055, MD211G5) and 5MP Color LCD Monitor CCL550i2 (CL21550) are intended to be used in displaying and viewing medical images for diagnosis by trained medical practitioners. They are to be used in digital mammography PACS, modalities including FFDM, and breast tomosynthensis

Device Description

MS55i2 (ML21055, MD211G5) is a 21.3 inch (54 cm) monochrome LCD monitor and CCL550i2 (CL21550) is a 21.3 inch (54 cm) color LCD monitor. Their displays' resolution is 2048 x 2560 (landscape), 2560 x 2048 (portrait) supporting DVI (digital visual interface) and DisplayPort.

AI/ML Overview

Here's a breakdown of the acceptance criteria and study information for the JVC Kenwood medical monitors, based on the provided FDA 510(k) summary:

1. Table of Acceptance Criteria and Reported Device Performance

The FDA 510(k) summary for the JVC KENWOOD monitors (MS55i2 and CCL550i2) primarily focuses on demonstrating substantial equivalence to a predicate device (EIZO RadiForce GX540) rather than presenting specific, quantitative acceptance criteria and results. The "acceptance criteria" can be inferred as matching or being equivalent to the key performance specifications of the predicate device, especially those related to image quality and functionality for diagnostic medical imaging.

Feature / Acceptance Criteria (Inferred from Predicate Equivalence)Predicate Device (EIZO RadiForce GX540) SpecificationJVC KENWOOD MS55i2 (ML21055, MD211G5) PerformanceJVC KENWOOD CCL550i2 (CL21550) Performance
Response Time (typical)25ms (On/Off)25ms (On/Off)25ms (On/Off)
Resolution or Matrix Size5MP (2048 x 2560)5MP (2048 x 2560)5MP (2048 x 2560)
Screen TechnologyTFT Monochrome LCD Panel (IPS)TFT Monochrome LCD Panel (IPS)TFT Color LCD Panel (IPS)
BacklightingLEDLEDLED
Maximum LuminanceMin. 850cd/m², Typ. 1200cd/m²Min. 850cd/m², Typ. 1200cd/m²Min. 700cd/m², Typ. 1000cd/m²
DICOM Calibrated Luminance500cd/m²500cd/m²500cd/m²
Viewing Angle (CR>50)Horizontal: Typ. 176°, Vertical: Typ. 176°Horizontal: Typ. 176°, Vertical: Typ. 176°Horizontal: Typ. 176°, Vertical: Typ. 176°
Display AreaHorizontal: 337.92mm, Vertical: 422.4mmHorizontal: 337.92mm, Vertical: 422.4mmHorizontal: 337.92mm, Vertical: 422.4mm
Aspect Ratio4:54:54:5
Pixel PitchHorizontal: 0.165mm, Vertical: 0.165mmHorizontal: 0.165mm, Vertical: 0.165mmHorizontal: 0.165mm, Vertical: 0.165mm
Contrast RatioMin. 900:1, Typ. 1200:1Min. 900:1, Typ. 1200:1Min. 1000:1, Typ. 1300:1
Grayscale Tones (10-bit DisplayPort)1,024 from a palette of 16,369 tones1,024 from a palette of 12,277 tones1,024 from a palette of 65,473 tones
Grayscale Tones (8-bit)256 from a palette of 16,369 tones256 from a palette of 12,277 tones256 from a palette of 65,473 tones
Non-Uniformity CompensationDigital Uniformity Equalizer (DUE)Digital Uniformity correction SystemDigital Uniformity correction System
Input Video SignalDVI-D x1, DisplayPort x1DVI-D x1, DisplayPort x1DVI-D x1, DisplayPort x1
QA SoftwareRadiCSQA Medivisor / Medivisor NX, F-CALQA Medivisor / Medivisor NX, F-CAL
Built-in Front SensorIntegrated Front Sensor (IFS)Built-in Front SensorBuilt-in Front Sensor
Ambient Light SensorAmbient Light Sensor (ALS)Built-in ambient Light SensorBuilt-in ambient Light Sensor

Explanation of Differences and Performance Justification:

  • Grayscale Tones: While the palette size for grayscale tones differs, the document states, "But our monitors pass the exams in AAPM-TG18 4.3 'Luminance Response'. Our monitors are equivalent to the predicated device." This indicates that despite the numerical difference in palette size, the devices meet the relevant image quality standards for grayscale reproduction.
  • Non-Uniformity Compensation: The JVC KENWOOD system is considered "equivalent to the predicated device's one" in making visual performance "much better in the point of luminance (monochrome and color version) and chromaticity."
  • Maximum Luminance (CCL550i2): The color monitor has a lower maximum luminance, but the document clarifies, "However DICOM Calibrated luminance is same as the predicated device. Then actual performance for diagnosis is the same." This is a crucial point, as the calibrated luminance is what's critical for diagnostic viewing.
  • Contrast Ratio (CCL550i2): The color model's contrast ratio is higher, which is generally a positive difference.

2. Sample Size Used for the Test Set and Data Provenance

This document does not contain information about a "test set" in the context of clinical images or patient data. The evaluation is focused on the technical performance specifications of the monitors themselves. Therefore, sample sizes for test sets in this sense are not applicable.

  • Data Provenance: The data presented is from the manufacturer's (JVC KENWOOD Corporation) testing and comparison against the specifications of the predicate device. The company is based in Japan. This is more akin to bench testing of hardware specifications rather than a clinical study with patient data.

3. Number of Experts Used to Establish the Ground Truth for the Test Set and Qualifications of Those Experts

Not applicable. This is a technical comparison of monitor specifications, not an evaluation of diagnostic accuracy based on expert interpretation of images. The "ground truth" here is the adherence to technical standards and performance specifications, likely established through engineering measurements and adherence to industry standards like AAPM-TG18.

4. Adjudication Method for the Test Set

Not applicable, as no human reader studies or clinical test sets requiring adjudication are described.

5. If a Multi-Reader Multi-Case (MRMC) Comparative Effectiveness Study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

Not applicable. This 510(k) summary is for medical display monitors and does not involve AI or reader studies.

6. If a Standalone (i.e., algorithm only without human-in-the-loop performance) was done

Not applicable. This 510(k) summary is for medical display monitors and does not involve algorithms or AI performance.

7. The Type of Ground Truth Used

The "ground truth" used in this submission is primarily technical specifications and performance measurements against established industry standards (e.g., DICOM, AAPM-TG18) and direct comparison with a legally marketed predicate device. The goal is to demonstrate that the new devices perform equivalently or better in terms of visual characteristics critical for medical image diagnosis.

8. The Sample Size for the Training Set

Not applicable. There is no AI algorithm being developed or trained described in this document.

9. How the Ground Truth for the Training Set was Established

Not applicable, as there is no training set mentioned in this document.

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Image /page/0/Picture/1 description: The image shows the logo for the Department of Health & Human Services - USA. The logo is a circular seal with the text "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" around the perimeter. Inside the circle is a stylized image of three human profiles facing to the right. The profiles are stacked on top of each other, with the top profile being the smallest and the bottom profile being the largest.

Food and Drug Administration 10903 New Hampshire Avenue Document Control Center - WO66-G609 Silver Spring, MD 20993-0002

February 23, 2016

JVC KENWOOD Corporation % Mr. Tsukasa Tashiro Engineering Specialist 3-12, Moriya-cho, Kanagawa-ku Yokohama, Kanagawa 221-0022 JAPAN

Re: K160326

Trade/Device Name: 5MP Monochrome LCD Monitor MS55i2 (ML21055, MD211G5) 5MP Color LCD Monitor CCL550i2 (CL21550) Regulation Number: 21 CFR 892.2050 Regulation Name: Picture archiving and communications system Regulatory Class: II Product Code: PGY Dated: January 29, 2016 Received: February 5, 2016

Dear Mr. Tashiro:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food. Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you, however, that device labeling must be truthful and not misleading.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); medical device reporting (reporting of medical device-related adverse events) (21 CFR 803); good manufacturing practice requirements as set

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forth in the quality systems (OS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050. If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Division of Industry and Consumer Education at its toll-free number (800) 638 2041 or (301) 796-7100 or at its Internet address

http://www.fda.gov/MedicalDevices/Resourcesfor You/Industry/default.htm. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21 CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to

http://www.fda.gov/MedicalDevices/Safety/ReportaProblem/default.htm for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance.

You may obtain other general information on your responsibilities under the Act from the Division of Industry and Consumer Education at its toll-free number (800) 638-2041 or (301) 796-7100 or at its Internet address

http://www.fda.gov/MedicalDevices/ResourcesforYou/Industry/default.htm.

Sincerely yours,

Robert Ocks

Robert Ochs, Ph.D. Director Division of Radiological Health Office of In Vitro Diagnostics and Radiological Health Center for Devices and Radiological Health

Enclosure

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DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration

Indications for Use

510(k) Number (if known)

K160326
Device Name

5MP Monochrome LCD Monitor MS55i2 (ML21055, MD211G5) 5MP Color LCD Monitor CCL550i2 (CL21550)

Indications for Use (Describe)

5MP Monochrome LCD Monitor MS55i2 (ML21055, MD211G5) and

5MP Color LCD Monitor CCL550i2 (CL21550)

are intended to be used in displaying and viewing medical images for diagnosis by trained medical practitioners. They are to be used in digital mammography PACS, modalities including FFDM, and breast tomosynthensis

Type of Use (Select one or both, as applicable)

Prescription Use (Part 21 CFR 801 Subpart D)

Over-The-Counter Use (21 CFR 801 Subpart C)

CONTINUE ON A SEPARATE PAGE IF NEEDED.

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DO NOT SEND YOUR COMPLETED FORM TO THE PRA STAFF EMAIL ADDRESS BELOW.

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Form Approved: OMB No. 0910-0120

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Image /page/3/Picture/0 description: The image shows the logo for JVC KENWOOD. The logo is in a dark blue color. Below the logo is the text "creates excitement & peace of mind" in a light blue color.

510(k) SUMMARY

Submitted Information:JVC KENWOOD Corporation3-12, Moriya-cho, Kanagawa-ku,Yokohama-shi, Kanagawa, 221-0022 Japan
Contact Person:Tsukasa Tashiro, Engineering SpecialistEmail: tashiro.tsukasa@jvckenwood.comTel: +81-258-24-6611Fax: +81-258-24-6617
Date Prepared:January 29, 2016
Device Name:1. 5MP Monochrome LCD Monitor MS55i2(ML21055, MD211G5)2. 5MP Color LCD Monitor CCL550i2(CL21550)
Common Name:1. MS55i2 (ML21055, MD211G5)2. CCL550i2 (CL21550)
Classification Name:Class II(Part 892 Radiology DevicesSec. 892.2050 Picture Archiving and Communication System)
Predicate Device:5MP Monochrome LCD Monitor, RadiForce GX540 (K151883)
Device Description:MS55i2 (ML21055, MD211G5) is a 21.3 inch (54 cm) monochromeLCD monitor and CCL550i2 (CL21550) is a 21.3 inch (54 cm) colorLCD monitor. Their displays' resolution is 2048 x 2560 (landscape),2560 x 2048 (portrait) supporting DVI (digital visual interface) andDisplayPort.
Intended Use:5MP Monochrome LCD Monitor MS55i2 (ML21055, MD211G5) and5MP Color LCD Monitor CCL550i2 (CL21550)are intended to be used in displaying and viewing medical imagesfor diagnosis by trained medical practitioners.They are to be used in digital mammography PACS, modalitiesincluding FFDM, and breast tomosynthensis

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Image /page/4/Picture/0 description: The image shows the JVC KENWOOD logo in dark blue. Below the logo is the text "creates excitement & peace of mind" in a lighter blue color. The logo is simple and modern, with a focus on the company's name and tagline.

510(k) SUMMARY

Substantial Equivalence:

LCD Monitor MS55i2(ML21055, MD211G5)

EIZO RadiForce GX540LCD Monitor MS55i2(ML21055, MD211G5)Explanation ofDifferences
510(k) NumberK151883K131137JVC KENWOOD usestypical data provided by thepanelmanufacturer.For further explanationrefer to temporal responseof MS55i2.
Response Time(typical)25ms (On/Off)25ms (On/Off)
Resolution orMatrix Size5MP(2048 x 2560)5MP(2048 x 2560)-
ScreenTechnologyTFT MonochromeLCD Panel (IPS)TFT MonochromeLCD Panel (IPS)-
BacklightingLEDLED-
MaximumLuminanceMin.850cd/m²Typ.1200cd/m².Min.850cd/m²Typ.1200cd/m².-
DICOMCalibratedLuminance500cd/m²500cd/m²-
Viewing AngleCR>50Horizontal: Typ.176Vertical: Typ.176CR>50Horizontal: Typ.176Vertical: Typ.176-
Display AreaHorizontal: 337.92mmVertical: 422.4mmHorizontal: 337.92mmVertical: 422.4mm-
Aspect Ratio4:54:5-
Pixel PitchHorizontal: 0.165mmVertical: 0.165mmHorizontal: 0.165mmVertical: 0.165mm-
Contrast RatioMin.900 : 1Typ.1200 : 1Min.900 : 1Typ.1200 : 1-
GrayscaleTones10-bit (DisplayPort): 1,024from a palette of 16,369tones8-bit: 256 from a palette of16,369 tones10-bit (DisplayPort): 1,024from a palette of 12,277 tones8-bit: 256 from a palette of12,277 tonesMaximum bit depth byDisplay port is 10 bit, it byDVI is 8 bit.Tone between the predicateddevice and our monitors aredifferent. But our monitorspass the exams inAAPM-TG18 4.3"Luminance Response".Our monitors are equivalentto the predicated device
Non-UniformityCompensationDigital UniformityEqualizer (DUE)Digital Uniformity correctionSystemOur Uniformitycorrection system isequivalent to thepredicated device's one.This system is helpful tomake visual performancemuch better in the pointof luminance(monochrome and colorversion) and chromaticity.
Input Video SignalDVI-D x1DisplayPort x1DVI-D x1DisplayPort x1-
ScanningFrequency31 - 135 kHz / 24 - 61 HzFrame synchronousmode: 24.5 - 25.5 Hz, 49- 51 HzPortrait:Horizontal:129.1KHzVertical:50HzLandscape:Horizontal:103.5KHzJVC KENWOOD specifiesonly maximum scanningfrequency which is based onthe LCD panel drivingspecification.
Vertical:50Hz
Dot Clock290MHz285 MHzJVC KENWOOD specifiesthe dot clock which is basedon the LCD panel drivingspecification.
PowerRequirementsAC 100 - 120 V,200 - 240 V: 50 / 60 HzAC100-240V, 50/60HzJVC KENWOODspecification covers powerrequirement specification ofthe predicated device.
Power108 W80W-
ConsumptionLess than 0.7 WLess than 2W-
PowerDVI DMPM,DVI DMPM,-
ManagementDisplayPort 1.1aDisplayPort 1.1a-
QA SoftwareRadiCSQA Medivisor / Medivisor NXF-CAL-
SensorIntegrated Front Sensor(IFS)Built- in Front Sensor-
Backlight Sensor (BS)NoneBrightness stability iscontrolled by the built-inFront sensor.
Ambient Light Sensor(ALS)Built-in ambient Light Sensor-
Presence Sensor (PS)None-
USB Ports /Standard1 upstream,2 downstream / Rev. 2.01 upstream,2 downstream / Rev. 2.0-
Dimensionsw/o Stand(W x H x D)388 x 496 x 99 mm(AR, N) 474.5 x 390 x 98.1 mm(F) 474.5 x 390 x 103.7 mm-
EIZO RadiForce GX540LCD Monitor CCL550i2(CL21550)Explanation of Differences
510(k) NumberK151883K151007-
Response Time(typical)25ms (On/Off)25ms (On/Off)JVC KENWOOD uses typical data provided by the panel manufacturer.For further explanation refer to temporal response of CCL550i2
Resolution orMatrix Size5MP(2048 x 2560)5MP(2048 x 2560)-
ScreenTechnologyTFT Monochrome LCD Panel (IPS)TFT Color LCD Panel (IPS)-
BacklightingLEDLED-
MaximumLuminanceMin.850cd/m2Typ.1200cd/m2.Min.700cd/m2Typ. 1000cd/m2Maximum luminance of color model is lower than monochrome panel.However DICOM Calibrated luminance is same as the predicated device.
DICOMCalibratedLuminance500cd/m2500cd/m2Then actual performance for diagnosis is the same.
Viewing AngleCR>50Horizontal: Typ.176Vertical: Typ.176CR>50Horizontal: Typ.176Vertical: Typ.176-
Display AreaHorizontal: 337.92mmVertical: 422.4mmHorizontal: 337.92mmVertical: 422.4mm-
Aspect Ratio4:54:5-
Pixel PitchHorizontal: 0.165mmVertical: 0.165mmHorizontal: 0.165mmVertical: 0.165mm-
Contrast RatioMin.900 : 1Typ.1200 : 1Min.1000 : 1Typ. 1300 : 1Contrast ratio of the color model is higher than the monochrome model.
GrayscaleTones10-bit (DisplayPort): 1,024 from a palette of 16,369 tones8-bit: 256 from a palette of 16,369 tones10-bit (DisplayPort): 1,024 from a palette of 65,473 tones8-bit: 256 from a palette of 65,473 tonesMaximum bit depth by Display port is 10 bit, it by DVI is 8 bit.Tone between the predicated device and our monitors are different. But our monitors pass the exams in AAPM-TG18 4.3 "Luminance Response".Our monitors are equivalent to the predicated device
Non-UniformityCompensationDigital Uniformity Equalizer (DUE)Digital Uniformity correction SystemOur Uniformity correction system is equivalent to the predicated device's one.This system is helpful to make visual performance much better in the point of luminance (monochrome and color version) and chromaticity.
Input Video SignalDVI-D x1DisplayPort x1DVI-D x1DisplayPort x1-
ScanningFrequency31 - 135 kHz / 24 - 61 HzFrame synchronous mode: 24.5 - 25.5 Hz, 49 - 51 HzPortrait:Horizontal: 129.1 KHzVertical: 50HzLandscape:Horizontal: 103.5 KHzVertical: 50HzJVC KENWOOD specifies only maximum scanning frequency which is based on the LCD panel driving specification.
Dot Clock290MHz285 MHzJVC KENWOOD specifies the dot clock which is based on the LCD panel driving specification.
PowerRequirementsAC 100 - 120 V,200 - 240 V: 50 / 60 HzAC100-240V, 50/60HzJVC KENWOODspecification covers powerrequirement specification ofthe predicated device.
Power108 W95W-
ConsumptionLess than 0.7 WLess than 2W-
PowerDVI DMPM,DVI DMPM,-
ManagementDisplayPort 1.1aDisplayPort 1.1a-
QA SoftwareRadiCSQA Medivisor / Medivisor NXF-CAL-
SensorIntegrated Front Sensor(IFS)Built- in Front Sensor-
Backlight Sensor (BS)NoneBrightness stability iscontrolled by the built-inFront sensor.
Ambient Light Sensor(ALS)Built-in ambient Light Sensor-
Presence Sensor (PS)None-
USB Ports /1 upstream,1 upstream,-
Standard2 downstream / Rev. 2.02 downstream / Rev. 2.0-
Dimensionsw/o Stand(W x H x D)388 x 496 x 99 mm(AR, N) 474.5 x 390 x 98.1 mm(F) 474.5 x 390 x 103.7 mm-

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MS55i2 adopts exactly the same panel as the predicated device, therefore its specification is completely same as the predicated device

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Maximum luminance of the CCL550i2-panel is low, but calibrated luminance at the time of factory shipment state is 500cd/m2.

This value is same as the predicated one. Moreover, contrast ratio of CCL550i2-panel is better, and other specifications in comparison items are similar. Therefore, our monitor is equivalent to the predicated device.

JVC KENWOOD Corporation Professional & Healthcare Division

3-12, Moriya-cho, Kanagawa-ku, Yokohama-shi, Kanagawa, 221-0022 Japan

§ 892.2050 Medical image management and processing system.

(a)
Identification. A medical image management and processing system is a device that provides one or more capabilities relating to the review and digital processing of medical images for the purposes of interpretation by a trained practitioner of disease detection, diagnosis, or patient management. The software components may provide advanced or complex image processing functions for image manipulation, enhancement, or quantification that are intended for use in the interpretation and analysis of medical images. Advanced image manipulation functions may include image segmentation, multimodality image registration, or 3D visualization. Complex quantitative functions may include semi-automated measurements or time-series measurements.(b)
Classification. Class II (special controls; voluntary standards—Digital Imaging and Communications in Medicine (DICOM) Std., Joint Photographic Experts Group (JPEG) Std., Society of Motion Picture and Television Engineers (SMPTE) Test Pattern).