K Number
K132304
Date Cleared
2013-08-21

(28 days)

Product Code
Regulation Number
892.1550
Reference & Predicate Devices
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows: Abdominal, Cardiac Adult, Cardiac other (Fetal), Cardiac Pediatric, Cerebral Vascular, Cephalic (Adult), Cephalic (Neonatal), Fetabl/Obstetric, Gynecological, Intraoperative (Vascular), Intraoperative (Cardiac), Musculoskeletal (Conventional), Musculoskeletal (Superficial), Other: Urology, Pediatric, Peripheral Vessel, Small Organ (Breast, Thyroid, Testicle), Transesophageal (Cardiac), Transrectal, Transvaginal. The clinical environments where the EPIQ Diagnostic Ultrasound System can be used include Clinics, Hospitals, and clinical point-of-care for diagnosis of patients.

Device Description

The EPIQ Diagnostic Ultrasound System is a general purpose, software controlled, diagnostic ultrasound system. Its function is to acquire ultrasound data and to display the data in various modes of operation. The device consists of two parts: the system console and the transducers. The system console contains the user interface, a display, system electronics and optional peripherals (ECG, printers). In addition to the physical knobs and buttons of the main control panel, the user interface consists of a touch screen with soft key controls, and a QWERTY keyboard. The removable transducers are connected to the system using a standard technology, multi-pin connectors. The EPIQ system uses standard transducer technology, and supports phased, linear, curved linear array, TEE, motorized 3D curved linear arrays as well as non-imaging (pencil) probes. Clinical data storage consists of a local repository as well as off-line image storage via the network, DVR, DVD, and USB storage devices. The images are stored in industrystandard formats (Ex: JPEG, AVI, DICOM) and are intended to be readable using industry-standard hardware and software. On-line review of the images is available. Secure access tools are provided to restrict and log access to the clinical data repository according to HIPAA. The system circuitry generates an electronic voltage pulse, which is transmitted to the transducer. In the transducer, a piezo electric array converts the electronic pulse into an ultrasonic pressure wave. When coupled to the body, the pressure wave transmits through body tissues. The Doppler functions of the system process the Doppler shift frequencies from the echoes of moving targets such as blood to detect and graphically display the Doppler shifts of these tissues as flow. The EPIQ system gives the operator the ability to measure anatomical structures and offers analysis packages that provide information used by competent healthcare professionals to make a diagnosis. The EPIQ system enables image guided navigation and image fusion via the optional PercuNav feature.

AI/ML Overview

The Philips EPIQ Diagnostic Ultrasound System, K132304, is a general-purpose, software-controlled diagnostic ultrasound system. It is designed to acquire ultrasound data and display it in various modes for diagnostic purposes across a wide range of clinical applications. Its acceptance for marketing was primarily based on substantial equivalence to predicate devices, rather than new clinical trials demonstrating de novo safety and effectiveness.

Here's an analysis based on the provided text:

1. Table of Acceptance Criteria and Reported Device Performance

The acceptance criteria for the EPIQ Diagnostic Ultrasound System are not presented as a direct performance table with numerical targets. Instead, acceptance is based on demonstrating substantial equivalence to previously cleared devices (Philips iU22 Diagnostic Ultrasound System, K130499, K121498, K093563, K042540, K030455) and compliance with relevant safety standards.

The reported device performance, in terms of meeting acceptance criteria for substantial equivalence, is articulated as follows:

Acceptance Criteria CategoryReported Device Performance (Summary)
Intended UseIdentical to predicate devices (diagnostic ultrasonic imaging and fluid flow analysis).
Indications for UseUnchanged from predicate devices, covering a broad range of clinical applications: Abdominal, Cardiac (Adult, Fetal, Pediatric, Trans-esophageal), Cerebral Vascular, Cephalic (Adult, Neonatal), Fetal/Obstetric, Gynecological, Intraoperative (Vascular, Cardiac), Musculoskeletal (Conventional, Superficial), Urology, Pediatric, Peripheral Vessel, Small Organ (Breast, Thyroid, Testicle), Transrectal, Transvaginal.
Technological CharacteristicsEmploys the "same fundamental scientific technology" as predicate (Track 3 system). Features like hard and soft keys are present on both, though their implementation may differ (e.g., more soft keys on EPIQ). Transducers use standard technology, with a new compact multi-pin connector being the primary hardware change.
Gray-scale and Doppler CapabilitiesIdentical to predicate devices.
Signal ProcessingEssentially the same as predicate devices.
Acoustic Output LimitsComplies with IEC 60601-2-37 Ed 2.0 and IEC 62359, Ed 2.0. Meets FDA ultrasound specific guidance (September 9, 2008).
Specific Acoustic Output ValuesIspta.3 ≤ 720 MW/cm²; MI < 1.9; TI < 6.0
Manufacturing QualityManufactured under equivalent quality systems as predicate devices.
BiocompatibilityPatient contact materials are not new and were previously cleared on the predicate iU22 system; evaluated and found to be safe.
Electrical and Physical SafetyDesigned and manufactured to the same electrical and physical safety standards (IEC 60601-1, IEC 60601-1-2, IEC 60601-1-6, IEC 60601-2-37, ISO 10993).
SoftwareSoftware Verification and Validation performed.
Risk ManagementRisk Analysis performed; Product Specifications, Design Reviews, Verification and Validation applied to system design and development.

2. Sample Size Used for the Test Set and Data Provenance

The document explicitly states: "A clinical trial was not required to demonstrate safety and effectiveness of the EPIQ Diagnostic Ultrasound System." This means there was no specific "test set" of patient data in the context of a clinical study to evaluate the device's diagnostic performance against a ground truth. The device's acceptance was based on non-clinical performance data and its substantial equivalence to previously cleared devices.

Therefore, there is no sample size for a test set of patient data as part of this 510(k) submission, and consequently, no data provenance regarding country of origin or retrospective/prospective nature of such a clinical test set.

3. Number of Experts Used to Establish Ground Truth and Qualifications

Since no clinical trial or test set with patient data was utilized for performance evaluation against a ground truth, there were no experts used to establish ground truth for a test set. The evaluation focused on engineering and regulatory compliance, and comparison to the predicate device's established performance.

4. Adjudication Method for the Test Set

As there was no clinical test set for performance evaluation, there was no adjudication method applied.

5. If a Multi-Reader Multi-Case (MRMC) Comparative Effectiveness Study was Done

No, an MRMC comparative effectiveness study was not done. The submission relies on substantial equivalence to demonstrate safety and effectiveness, rather than a direct comparison of human readers with and without AI assistance. The device is purely a diagnostic imaging system, not an AI-assisted diagnostic tool in the sense of improving human reader performance.

6. If a Standalone (i.e., algorithm only without human-in-the-loop performance) was Done

The device is a diagnostic ultrasound system. Its "performance" is inherent in its ability to acquire and display ultrasound data accurately according to its specifications and the standards it complies with. It is not an "algorithm only" device that provides interpretations or diagnoses. Its performance is fundamentally linked to human operation and interpretation. Therefore, the concept of "standalone performance" as it might apply to an AI algorithm providing diagnostic outputs (e.g., sensitivity/specificity) is not relevant or applicable here. The non-clinical performance data (e.g., phantom imaging, acoustic output measurements) would be a form of standalone testing of the system's technical capabilities.

7. The Type of Ground Truth Used

For non-clinical performance data validation, the "ground truth" would be established by technical standards and physical measurements (e.g., phantom studies for image quality, calibrated sensors for acoustic output, engineering specifications for software and hardware functionality). There was no "expert consensus, pathology, or outcomes data" ground truth used for determining the device's diagnostic accuracy in a clinical context within this submission, as a clinical trial was not performed.

8. The Sample Size for the Training Set

The document does not describe the development of a specific "training set" in the context of machine learning or AI models. The EPIQ Diagnostic Ultrasound System is presented as an evolution of existing ultrasound technology (Track 3 system and identical fundamental scientific technology to the predicate device). Therefore, there is no stated sample size for a training set as this is not a submission for an AI/ML-driven device that requires such training data to establish its core functionality.

9. How the Ground Truth for the Training Set was Established

Since no training set for an AI/ML model is mentioned or appears to be relevant to this submission, the question of how its ground truth was established is not applicable. The ground truth for validating the system's performance would relate to engineering and regulatory standards, and established metrics for ultrasound image quality and safety.

{0}------------------------------------------------

K132304

510(k) Summary of Safety and Effectiveness EPIQ Diagnostic Ultrasound System

This summary of safety and effectiveness information is submitted in accordance with 21CFR §807.92

    1. Submitter's name, address, telephone number, contact person. Philips Ultrasound, Inc. 22100 Bothell Everett Hwy Bothell, WA 98021-8431
      AUG
      21 2013

Jessica Stenberg, Regulatory Affairs Specialist Contact person: Email: Jessica. Stenberg@philips.com Tel: (425) 487-7371 Fax: (425) 487-8666

Date prepared: June 27th, 2013

    1. Name of the device, including the trade or proprietary name if applicable, the common or usual name, and the classification name, if known:
      Common/usual name: Diagnostic ultrasound system and transducers Proprietary name: EPIQ Ultrasound System

These devices are classified as follows:

Classification Name21 CFR SectionProduct Code
Ultrasonic Pulsed Doppler Imaging System892.1550IYN
Ultrasonic Pulsed Echo Imaging System892.1560IYO
Diagnostic Ultrasound Transducer892.1570ITX

As stated in 21 CFR, parts 892.1550, 892.1560, 892.1570, and 892.1750 each of these generic types of devices have been classified as Class II.

3. Substantially Equivalent Devices

Philips Ultrasound believes the EPIQ Ultrasound System is substantially equivalent to the following currently marketed devices:

Product510(k)
Philips iU22 Diagnostic Ultrasound SystemK130499, K121498, K093563, K042540,K030455

{1}------------------------------------------------

4. Device Description

The EPIQ Diagnostic Ultrasound System is a general purpose, software controlled, diagnostic ultrasound system. Its function is to acquire ultrasound data and to display the data in various modes of operation.

The device consists of two parts: the system console and the transducers. The system console contains the user interface, a display, system electronics and optional peripherals (ECG, printers). In addition to the physical knobs and buttons of the main control panel, the user interface consists of a touch screen with soft key controls, and a QWERTY keyboard.

The removable transducers are connected to the system using a standard technology, multi-pin connectors. The EPIQ system uses standard transducer technology, and supports phased, linear, curved linear array, TEE, motorized 3D curved linear arrays as well as non-imaging (pencil) probes.

Clinical data storage consists of a local repository as well as off-line image storage via the network, DVR, DVD, and USB storage devices. The images are stored in industrystandard formats (Ex: JPEG, AVI, DICOM) and are intended to be readable using industry-standard hardware and software. On-line review of the images is available. Secure access tools are provided to restrict and log access to the clinical data repository according to HIPAA.

The system circuitry generates an electronic voltage pulse, which is transmitted to the transducer. In the transducer, a piezo electric array converts the electronic pulse into an ultrasonic pressure wave. When coupled to the body, the pressure wave transmits through body tissues. The Doppler functions of the system process the Doppler shift frequencies from the echoes of moving targets such as blood to detect and graphically display the Doppler shifts of these tissues as flow.

The EPIQ system gives the operator the ability to measure anatomical structures and offers analysis packages that provide information used by competent healthcare professionals to make a diagnosis. The EPIQ system enables image guided navigation and image fusion via the optional PercuNav feature

5. Technological Comparison to Predicate Devices

The EPIQ system is based on the latest technology in circuitry, memory, and essential hardware. While this hardware is new, the intended use and indications for use of the device remain unchanged from the Predicate iU22 system (K130499, K121498, K093563, K042540, K030455).

{2}------------------------------------------------

Both the EPIQ system and the predicate iU22 use both hard and soft keys for operating controls. On the EPIQ system hard keys (knobs, buttons) have been changed to soft keys.

The EPIQ system offers a suite of transducers which have essentialy the same hardware save the connector. The EPIQ system has a new multipin connector which is compact as in comparison to the iU22 transducer connectors. The transducers represent the only patient contact materials of the Ultrasound System. The EPIQ system introduces no new patient contact materials that have not been previously cleared on the predicate iU22 system.

The EPIQ system is a Track 3 system that employs the same fundamental scientific technology as the predicate iU22 system.

6. Indications for Use

Abdominal, Cardiac Adult, Cardiac other (Fetal), Cardiac Pediatric, Cerebral Vascular, Cephalic (Adult), Cephalic (Neonatal), Fetabl/Obstetric, Gynecological, Intraoperative (Vascular), Intraoperative (Cardiac), Musculoskeletal (Conventional), Musculoskeletal (Superficial), Other: Urology, Pediatric, Peripheral Vessel, Small Organ (Breast, Thyroid, Testicle), Transesophageal (Cardiac), Transrectal, Transvaginal.

The clinical environments where the EPIQ Diagnostic Ultrasound System can be used include Clinics, Hospitals, and clinical point-of-care for diagnosis of patients.

7. Safety Considerations

As a track 3 ultrasound device the EPIQ Ultrasound System is designed to comply with the acoustic output display requirements of IEC 60601-2-37 Ed 2.0 (Particular requirements for the basic safety and essential performance of ultrasonic medical and monitoring equipment) and IEC 62359, Ed 2.0 (Ultrasonics - Field characterization - Test methods for the determination of thermal and mechanical indices related to medical diagnostic ultrasonic fields).

The EPIQ Ultrasound System complies with the referenced standard as well as the FDA ultrasound specific guidance for Industry and FDA Staff - Information for Manufacturers Seeking Marketing Clearance of Diagnostic Ultrasound Systems and Transducers (September 9, 2008).

The system acoustic output limits are:

  • Ispta.3 ≤ 720 MW/cm² .
  • . MI < 1.9
  • . 11 < 6.0

The system and transducers are compliant to:

{3}------------------------------------------------

  • . IEC 60601-1: Medical electrical equipment. General requirements for basic safety and essential performance, 2005, Amendment 1, 2012
  • · IEC 60601-1-2 Medical Electrical Equipment Part 1-2, General Requirements for Basic Safety and Essential Performance – Collateral Standard Electromagnetic Compatibility, 2007
  • · IEC 60601-1-6 Medical Electrical Equipment Part 1-6, General Requirements for Basic Safety and Essential Performance – Usability, 2010
  • · IEC 60601-2-37: Medical electrical equipment. Particular requirements for the basic safety and essential performance of ultrasonic medical diagnostic and monitoring equipment, 2007
  • · IEC 62359, Ultrasonics Field characterization Test methods for the determination of thermal and mechanical indices related to medical diagnostic ultrasonic fields, 2010

8. Nonclinical Performance Data

Philips Ultrasound performed the following testing to ensure the safety and effectiveness of the EPIQ device:

  • . Software Verification and Validation
  • . Non-Clinical Performance Data
  • . Non-Clinical Tests
    • . IEC 60601-1: Medical electrical equipment. General requirements for basic safety and essential performance, 2005, Amendment 1, 2012
    • . IEC 60601-1-2 Medical Electrical Equipment – Part 1-2, General Requirements for Basic Safety and Essential Performance – Collateral Standard Electromagnetic Compatibility, 2007
    • . IEC 60601-1-6 Medical Electrical Equipment - Part 1-6, General Requirements for Basic Safety and Essential Performance - Usability, 2010
    • . IEC 60601-2-37: Medical electrical equipment. Particular requirements for the basic safety and essential performance of ultrasonic medical diagnostic and monitoring equipment, 2007
    • ISO 10993: Biological evaluation of medical devices. .
  • . Quality assurance measures applied to the system design and development include, but were not limited to:
    • . Risk Analysis
    • . Product Specifications
    • Design Reviews ●
    • . Verification and Validation

{4}------------------------------------------------

9. Clinical Data

A clinical trial was not required to demonstrate safety and effectiveness of the EPIQ Diagnostic Ultrasound System. Clinical validation is unnecessary as EPIQ introduces no new indications for use, no new modes or features that have not been previously cleared on the identified predicates. The clinical safety and effectiveness of ultrasound systems with these characteristics are historically accepted for both predicate and subject devices.

10. Conclusion

The EPIQ Ultrasound System and transducers is substantially equivalent in safety and effectiveness to the predicate devices identified above:

  • . The predicate devices and EPIQ are indicated for the diagnostic ultrasonic imaging and fluid flow analysis.
  • . The predicate devices and EPIQ have the same gray-scale and Doppler capabilities.
  • . The predicate devices and EPIQ use essentially the same technologies for imaging, Doppler functions and signal processing.
  • . The predicate devices and EPIQ have acoustic output levels within the Track 3 FDA limits.
  • The predicate devices and EPIQ are manufactured under equivalent quality . systems.
  • . The predicate devices and EPIQ are manufactured of materials with equivalent bio safety. The materials have been evaluated and found to be safe for this application.
  • . The predicate devices and EPIQ are designed and manufactured to the same electrical and physical safety standards.

514 Performance Standards

There are no Sec. 514 performance standards for this device.

Prescription Status

This is a prescription device. The prescription device statement appears in the labeling.

Sterilization Sites

Not applicable. No components supplied sterile.

Track This is a Track 3 system

{5}------------------------------------------------

Image /page/5/Picture/1 description: The image shows the logo for the U.S. Department of Health & Human Services. The logo consists of a circular seal with the text "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" arranged around the perimeter. Inside the circle is a stylized symbol resembling an eagle or bird in flight, composed of three curved lines. The symbol is positioned to the right of the text.

Food and Drug Administration 10903 New Hampshire Avenue Document Control Center - WO66-G609 Silver Spring, MD 20993-0002

August 21, 2013

PHILIPS ULTRASOUND, INC. C/O MARK JOB REVIEWER REGULATORY TECHNOLOGY SERVICES LLC 1394 25TH STREET NW BUFFALO MN 55313

Re: K132304

Trade/Device Name: EPIQ Diagnostic Ultrasound System Regulation Number: 21 CFR 892.1550 Regulation Name: Ultrasonic pulsed doppler imaging system Regulatory Class: II Product Code: IYN, IYO, ITX Dated: July 23, 2013 Received: July 29, 2013

Dear Mr. Job:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you, however, that device labeling must be truthful and not misleading.

This determination of substantial equivalence applies to the following transducers intended for use with the Philips EPIO Diagnostic Ultrasound System. as described in your premarket notification:

Transducer Model Number
C5-1C8-5C9-2
C10-3vC10-4ecD2cwc
D2tcdD5cwcL12-3
L12-5 50L15-7ioL18-5
S5-1S7-3tS8-3
S12-4V6-2X5-1
X6-1X7-2t

{6}------------------------------------------------

Page 2-Mr. Job

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807): labeling (21 CFR Part 801); medical device reporting (reporting of medical device-related adverse events) (21 CFR 803); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Division of Small Manufacturers, International and Consumer Assistance at its tollfree number (800) 638 2041 or (301) 796-7100 or at its Internet address

http://www.fda.gov/MedicalDevices/ResourcesforYou/Industry/default.htm. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to

http://www.fda.gov/MedicalDevices/Safety/ReportaProblem/dcfault.htm for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance.

You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 796-7100 or at its Internet address http://www.fda.gov/MedicalDevices/ResourcesforYou/Industry/default.htm.

Sincercly yours.

Smh.7)

for

Janine Morris Director, Division of Radiological Health Office of In Vitro Diagnostics and Radiological Health Center for Devices and Radiological Health

Enclosure

{7}------------------------------------------------

Indications for Use

K132304 510(k) Number (if known):

Device Name: Philips EPIQ Diagnostic Ultrasound System

Indications for Use:

Fetal/Obstetric Gynecological Intra-operative (Vascular, Cardiac) Abdominal Pediatric Small Organ (Breast, Thyroid, Testicle) Cephalic (Adult, Neonatal) Trans-rectal Trans-vaginal Musculoskeletal (Conventional and Superficial) Urology Cardiac (Adult, Pediatric, Fetal, Trans-esophageal) Fetal Echo Peripheral Vessel Vascular (Cerebral)

The clinical environments where the EPIQ Diagnostic Ultrasound System can be used include Clinics, Hospitals, and clinical point-of-care for diagnosis of patients.

Prescription Use __ X_ (Part 21 CFR 801 Subpart D) AND/OR

Over-The-Counter Use ____ (21 CFR 807 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of In Vitro Diagnostics and Radiological Health (OlR)

Michael D. O'Hara

(Division Sign Off) Division of Radiological Health Office of In Vitro Diagnostic and Radiological Health

510(k) K132304

Page 11 of 121

{8}------------------------------------------------

:10(k) No: _

System: EPIQ Ultrasound System

510(k) No: ___________________________________________________________________________________________________________________________________________________________________ Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Clinical ApplicationMode of Operation {*includes simultaneous B-mode}
GeneralSpecificBMPWDCWDCalorCombinedOther
(Track I only)(Tracks & III)Doppler*(Spec.)(Spec.)
OphthalmicOphthalmic
Fetal / OBNNત્ત્વNNote: 1,2,3Note: 5,6,7,8,9,10,12,13,17
AbdominalNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,15,16,17
Intra-operative (Cardiac)ત્તNNNNote: 1,2,3Note: 5,8,9,10,11,12,13
Intra-operative (Vascular)NNત્વNote: 1,2,3Note: 5,8,9,10,11,12.13
Fetal ImagingLaparoscopic
& OtherPediatricNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
Small Organ (breast, thyroid,testicle)NNNNote: 1,2,3Note:5,6,8,9,10,11.12,13,15,17
Neonatal CephalicNNNNNote: 1,2,3Note: 5,8,9,10,11,12,13,17
Adult CephalicNగ్NNNote: 1,2,3Note: 8,9,10,11,12,13,17
Trans-rectalNNડીNNote: 1,2,3Note:5,6,8,9,10,11,12,13,15,17
Trans-vaginalNNNote: 1.2,3Note:5,6,7,8,9,10,11,12,13,15,17
Trans-urethral
Trans-esoph, (non-Cardiac)
Musculo-skel. (Conventional)NNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
Musculo-skel. (Superficial)NNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
Intra-luminal
Other: GYNNNNNNote: 1,2,3Note:5,6,7,8,9,10,11,12,13,15,17
Other: UrologyNNNNNote: 1,2,3Note:5,6,8,9,10,11,12,13,15,17
CardiacCardiac AdultNನಿNNNote: 1,2,3,4Note: 10,11,12,13,14
Cardiac PediatricNત્વNNote: 1,2,3,4Note: 10,11,12,13,14
Trans-esophageal (Cardiac)Nાર્તNNote: 1,2,3,4Note: 10,11,12,13,14
Other (Fetal Echo)NNNNote: 1,2,3,4Note: 5,6,8,10,12,13,14
PeripheralPeripheral vesselNNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
VesselCerebral vascularહિNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
N= new indicationAdditional Comments:
*Color Doppler includes Color Amplitude DopplerNote 9: Color Power Angio (CPA)
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude;B+MNote 10: Harmonic Imaging
Note 2: Combined modes include: B+M+ColorNote 11: Contrast Imaging
Note 3: Combined modes include: B+Color+PWD;B+Amplitude+PWDNote 12: 3D/4D Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD;B+Amplitude+CWDNote 13: XRES
Note 5: SonoCTNote 14: TDI
Note 6: Imaging for guidance of biopsyNote 15: Elastography
Note 7: Infertility monitoring of follicle developmentNote 16: ElastPQ (for Liver)
Note 8: Panoramic ImagingNote 17: PercuNav

:

{9}------------------------------------------------

510(k) No:

510(k) No:
System:EPIQ Ultrasound System
Transducer:CS-1
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal / OBNNNNNote: 1,2,3Note: 5,6,7,8,9,10,12,13
AbdominalNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,16,17
Fetal Imaging& OtherIntra-operative (Cardiac)
Intra-operative (Vascular)
Laparoscopic
PediatricNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
Small Organ (breast, thyroid, testicle)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)
Musculo-skel. (Superficial)
Intra-luminal
Other: GYNNNNNNote: 1,2,3Note: 5,6,7,8, 910,11,12,13,17
Other: UrologyNNNNNote: 1,2,3Note: 5,6,,8, 9,10,11,12,13,17
CardiacCardiac Adult
Cardiac Pediatric
Trans-esophageal (Cardiac)
Other (Fetal Echo)NNNNNote: 1,2,3Note: 5,6,10,12,13
PeripheralVesselPeripheral vesselNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
Cerebral vascular
N= new indication
Additional Comments:
*Color Doppler includes Color Amplitude DopplerNote 9: Color Power Angio (CPA)
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude;B+MNote 10: Harmonic Imaging
Note 2: Combined modes include: B+M+ColorNote 11: Contrast Imaging
Note 3: Combined modes include: B+Color+PWD;B-Amplitude+PWDNote 12: 3D/4D Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD;8-Amplitude+CWDNote 13: XRES
Note 5: SonoCTNote 14: TDI
Note 6: Imaging for guidance of biopsyNote 15: Elastography
Note 7: Infertility monitoring of follicle developmentNote 16: ElastPQ (for Liver)
Note 8: Panoramic ImagingNote 17: PercuNav
510(k) No:
System:EPIQ Ultrasound System
Transducer:C8-5
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal Imaging& OtherFetal / OB
AbdominalNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13
Intra-operative (Cardiac)
Intra-operative (Vascular)
Laparoscopic
PediatricNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13
Small Organ (breast, thyroid, testicle)
Neonatal CephalicNNNNNote: 1,2,3Note: 5,6,8,9,10,12,13
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)
Musculo-skel. (Superficial)
Intra-luminal
Other: GYN
Other: Urology
CardiacCardiac Adult
Cardiac Pediatric
Trans-esophageal (Cardiac)
Other (Fetal Echo)
PeripheralVesselPeripheral vesselNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13
Cerebral VascularNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13
N= new indication
Additional Comments:Note 9: Color Power Angio (CPA)
*Color Doppler includes Color Amplitude DopplerNote 1: Combined modes include: B+PWD; B+Color; B+Amplitude;B+MNote 10: Harmonic Imaging
Note 2: Combined modes include: B+M+ColorNote 3: Combined modes include: B+Color+PWD;B+Amplitude+PWDNote 11: Contrast Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD;B+Amplitude+CWDNote 12: 3D/4D Imaging
Note 5: SonoCTNote 13: XRES
Note 6: Imaging for guidance of biopsyNote 14: TDI
Note 7: Infertility monitoring of follicle developmentNote 15: Elastography
Note 8: Panoramic ImagingNote 16: ElastPQ (for Liver)

{10}------------------------------------------------

{11}------------------------------------------------

510(k) No:
System:EPIQ Ultrasound System
Transducer:C9-2
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Mode of Operation (*includes simultaneous B-mode)
GeneralClinical ApplicationSpecificColorCombined *Other
(Track I only)(Tracks I & III)BMPWDCWDDoppler*(Spec.)(Spec.)
OphthalmicOphthalmic
Fetal / OBNote: 5,6,7,8,9,10,12,13,17
NNNNNote: 1,2,3
AbdominalNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
Intra-operative (Cardiac)
Intra-operative (Vascular)
Fetal ImagingLaparoscopic
& OtherPediatricNote: 5,6,8,9,10,11,12,13,17
NNNNNote: 1,2,3
Small Organ (breast, thyroid,
testicle)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)
Musculo-skel. (Superficial)
Intra-luminalNote: 5,6,8,9,10,11,12,13,17
Other: GYNNNNNNote: 1,2,3
Other: UrologyNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (Fetal Echo)NNNNNote: 1,2,3Note: 5,6,10,12,13
PeripheralPeripheral vesselNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
VesselCerebral Vascular
N= new indication
Additional Comments:
* Color Doppler includes Color Amplitude DopplerNote 9: Color Power Angio (CPA)
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude;Note 10: Harmonic Imaging
B+MNote 2: Combined modes include: B+M+ColorNote 11: Contrast Imaging
Note 3: Combined modes include: B+Color+PWD;
B+Amplitude+PWDNote 12: 3D/4D Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD;Note 13: XRES
Note 5: SonoCTB+Amplitude+CWDNote 14: TDI
Note 6: Imaging for guidance of biopsyNote 15: Elastography
Note 7: Infertility monitoring of follicle developmentNote 16: ElastPQ (for Liver)
Note 8: Panoramic ImagingNote 17: PercuNav
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
GeneralSpecificBMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
(Track I only)(Tracks I & III)
OphthalmicOphthalmic
Fetal / OBNNNNNote: 1,2,3Note:5,6,7,8,9,10,12,13,17
Abdominal
Intra-operative (Cardiac)
Intra-operative (Vascular)
Fetal Imaging& OtherLaparoscopic
Pediatric
Small Organ (breast, thyroid,testicle)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginalNNNNNote: 1,2,3Note:5,6,7,8,9,10,11,12,13,15,17
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)
Musculo-skel. (Superficial)
Intra-luminal
Other: GYNNNNNNote: 1,2,3Note:5,6,7,8,9,10,11,12,13,15,17
Other: UrologyNNNNNote: 1,2,3Note:5,6,7,8,9,10,11,12,13,15,17
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (Fetal Echo)NNNNNote: 1,2,3Note: 5,6,8,10,12,13
PeripheralVesselPeripheral vessel
Cerebral Vascular
N= new indication
Additional Comments:
*Color Doppler includes Color Amplitude DopplerNote 9: Color Power Angio (CPA)
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude;B+MNote 10: Harmonic Imaging
Note 2: Combined modes include: B+M+ColorNote 11: Contrast Imaging
Note 3: Combined modes include: B+Color+PWD;B+Amplitude+PWDNote 12: 3D/4D Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD;B+Amplitude+CWDNote 13: XRES

{12}------------------------------------------------

Note 6: Imaging for guidance of biopsy

Note 8: Panoramic Imaging

Note 7: Infertility monitoring of follicle development

DIAGNOSTIC ULTRASOUND INDICATIONS FOR USE STATEMENT

510(k) No: EPIQ Ultrasound System System: Transducer: C10-3v Intended Use:

Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Note 15: Elastography Note 16: ElastPQ {for Liver)

Note 17: Percu Nav

{13}------------------------------------------------

Note 5: SonoCT

Note 6: Imaging for guidance of biopsy

Note 8: Panoramic Imaging

Note 7: Infertility monitoring of follicle development

DIAGNOSTIC ULTRASOUND INDICATIONS FOR USE STATEMENT

510(k) No: EPIQ Ultrasound System System: C10-4ec Transducer: Intended Use:

Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
GeneralSpecificBMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
(Track I only)(Tracks I & III)
OphthalmicOphthalmic
Fetal / OBNNNNNote: 1,2,3Note: 5,6,8,9,10,12,13,17
Abdominal
Intra-operative (Cardiac)
Intra-operative (Vascular)
Fetal Imaging& OtherLaparoscopic
Pediatric
Small Organ (breast, thyroid,testicle)
Neonatal Cephalic
Adult Cephalic
Trans-rectalNNNNNote: 1,2,3Note: 5,6,7,8,9,10,11,12,13,17
Trans-vaginalNNNNNote: 1,2,3Note: 5,6,7,8,9,10,11,12,13,17
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)
Musculo-skel. (Superficial)
Intra-luminal
Other: GYNNNNNNote: 1,2,3Note:5,6,7,8,9,10,11,12,13,17
Other: UrologyNNNNNote: 1,2,3Note:5,6,7,8,9,10,11,12,13,17
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (Fetal Echo)NNNNNote: 1,2,3Note: 5,8,9,10,12,13
PeripheralPeripheral vesselNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
VesselCerebral Vascular
N= new indication
Additional Comments:
*Color Doppler includes Color Amplitude DopplerNote 9: Color Power Angio (CPA)
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude;B+MNote 10: Harmonic Imaging
Note 2: Combined modes include: B+M+ColorNote 11: Contrast Imaging
Note 3: Combined modes include: B+Color+PWD;Note 12: 3D/4D Imaging
B+Amplitude+PWDNote 4: Combined modes include: B+CWD; B+Color+CWD;Note 13: XRES

Note 14: TDI Note 15: Elastography

Note 17: PercuNav

Note 16: ElastPQ (for Liver)

{14}------------------------------------------------

Note 8: Panoramic Imaging

DIAGNOSTIC ULTRASOUND INDICATIONS FOR USE STATEMENT

510(k) No: System: EPIQ Ultrasound System Transducer: D2cwc Intended Use:

Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal / OB
Abdominal
Intra-operative (Cardiac)
Intra-operative (Vascular)
Fetal Imaging& OtherLaparoscopic
Pediatric
Small Organ (breast, thyroid,testicle)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)
Musculo-skel. (Superficial)
Intra-luminal
Other: GYN
Other: Urology
Cardiac AdultN
CardiacCardiac PediatricN
Trans-esophageal (Cardiac)
Other (Fetal Echo)
PeripheralVesselPeripheral vessel
Cerebral Vascular
N= new indication
Additional Comments:
*Color Doppler includes Color Amplitude DopplerNote 9: Color Power Angio (CPA)
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude;B+MNote 10: Harmonic Imaging
Note 2: Combined modes include: B+M+ColorNote 11: Contrast Imaging
Note 3: Combined modes include: B+Color+PWD;B+Amplitude+PWDNote 12: 3D/4D Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD;B+Amplitude+CWDNote 13: XRES
Note 5: SonoCTNote 14: TDI
Note 6: Imaging for guidance of biopsyNote 15: Elastography
Note 7: Infertility monitoring of follicle developmentNote 16: ElastPQ (for Liver)

Note 17: Percu Nav

{15}------------------------------------------------

DIAGNOSTIC ULTRASOUND INDICATIONS FOR USE STATEMENT

510(k) No: EPIQ Ultrasound System System: Transducer: D2tcd Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler *Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal / OB
Abdominal
Intra-operative (Cardiac)
Intra-operative (Vascular)
Fetal Imaging& OtherLaparoscopic
Pediatric
Small Organ (breast, thyroid,testicle)
Neonatal Cephalic
Adult CephalicN
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)
Musculo-skel. (Superficial)
Intra-luminal
Other: GYN
Other: Urology
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (Fetal Echo)
PeripheralVesselPeripheral vessel
Cerebral VascularN
N= new indicationAdditional Comments:
* Color Doppler includes Color Amplitude DopplerNote 9: Color Power Angio (CPA)
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude;B+MNote 10: Harmonic Imaging
Note 2: Combined modes include: B+M+ColorNote 11: Contrast Imaging
Note 3: Combined modes include: B+Color+PWD;B+Amplitude+PWDNote 12: 3D/4D Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD;B+Amplitude+CWDNote 13: XRES
Note 5: SonoCTNote 14: TDI
Note 6: Imaging for guidance of biopsyNote 15: Elastography
Note 7: Infertility monitoring of follicle developmentNote 16: ElastPQ (for Liver)
Note 8: Panoramic ImagingNote 17: PercuNav

{16}------------------------------------------------

diagnostic ultrasound Indications for use statement

510(k) No:
System:EPIQ Ultrasound System
Transducer:D5cwc
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal Imaging& OtherFetal / OB
Abdominal
Intra-operative (Cardiac)
Intra-operative (Vascular)
Laparoscopic
Pediatric
Small Organ (breast, thyroid,testicle)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)
Musculo-skel. (Superficial)
Intra-luminal
Other: GYN
Other: Urology
CardiacCardiac Adult
Cardiac Pediatric
Trans-esophageal (Cardiac)
Other (Fetal Echo)
PeripheralVesselPeripheral vesselN
Cerebral VascularN
N= new indication
Additional Comments:
*Color Doppler includes Color Amplitude DopplerNote 9: Color Power Angio (CPA)
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude;B+MNote 10: Harmonic Imaging
Note 2: Combined modes include: B+M+ColorNote 11: Contrast Imaging
Note 3: Combined modes include: B+Color+PWD;B+Amplitude+PWDNote 12: 3D/4D Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD;B+Amplitude+CWDNote 13: XRES
Note 5: SonoCTNote 14: TDI
Note 6: Imaging for guidance of biopsyNote 15: Elastography
Note 7: Infertility monitoring of follicle developmentNote 16: ElastPQ (for Liver)
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal Imaging& OtherFetal / OB
AbdominalNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
Intra-operative (Cardiac)
Intra-operative (Vascular)
Laparoscopic
Pediatric
Small Organ (breast, thyroid, testicle)NNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
Neonatal CephalicNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)NNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
Musculo-skel. (Superficial)NNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
Intra-luminal
Other: GYN
Other: Urology
CardiacCardiac Adult
Cardiac Pediatric
Trans-esophageal (Cardiac)
Other (Fetal Echo)
PeripheralVesselPeripheral vesselNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17
Cerebral VascularNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13,17

{17}------------------------------------------------

510(k) No:

DIAGNOSTIC ULTRASOUND INDICATIONS FOR USE STATEMENT

* Color Doppler includes Color Amplitude DopplerNote 9: Color Power Angio (CPA)
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude;B+MNote 10: Harmonic Imaging
Note 2: Combined modes include: B+M+ColorNote 11: Contrast Imaging
Note 3: Combined modes include: B+Color+PWD;B+Amplitude+PWDNote 12: 3D/4D Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD;B+Amplitude+CWDNote 13: XRES
Note 5: SonoCTNote 14: TDI
Note 6: Imaging for guidance of biopsyNote 15: Elastography
Note 7: Infertility monitoring of follicle developmentNote 16: ElastPQ (for Liver)
Note 8: Panoramic ImagingNote 17: PercuNav

{18}------------------------------------------------

DIAGNOSTIC ULTRASOUND INDICATIONS FOR USE STATEMENT

510(k) No: EPIQ Ultrasound System System: Transducer: L12-5 50 Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows: Intended Use:

Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal / OBNNNNNote: 1,2,3Note: 5,6,8,9,10,12,13
AbdominalNNNNNote: 1,2,3Note:5,6,8,9,10,11,12,13,15,17
Intra-operative (Cardiac)
Intra-operative (Vascular)
Fetal Imaging& OtherLaparoscopic
PediatricNNNNNote: 1,2,3Note: 5,6,8,10,11,12,13,17
Small Organ (breast, thyroid,testicle)NNNNNote: 1,2,3Note:5,6,8,9,10,11,12,13,15,17
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)NNNNNote: 1,2,3Note:5,6,8,9,10,11,12,13,17
Musculo-skel. (Superficial)NNNNNote: 1,2,3Note:5,6,8,9,10,11,12,13,17
Intra-luminal
Other: GYN
Other: Urology
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (Fetal Echo)
PeripheralVesselPeripheral vesselNNNNNote: 1,2,3Note:5,6,8,9,10,11,12,13,17
Cerebral VascularNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13
N= new indicationAdditional Comments:

*Color Doppler includes Color Amplitude Doppler Note 9: Color Power Angio (CPA) Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude; Note 10: Harmonic Imaging B+M Note 2: Combined modes include: B+M+Color Note 11: Contrast Imaging Note 3: Combined modes include: 8+Color+PWD; Note 12: 3D/4D Imaging B+Amplitude+PWD Note 4: Combined modes include: 8+CWD; B+Color+CWD; Note 13: XRES B+Amplitude+CWD Note 5: SonoCT Note 14: TDI Note 15: Elastography Note 6: Imaging for guidance of biopsy Note 7: Infertility manitoring of follicle development Note 16: ElastPQ (for Liver) Note 8: Panoramic Imaging Note 17: Percu Nav

{19}------------------------------------------------

DIAGNOSTIC ULTRASOUND INDICATIONS FOR USE STATEMENT

510(k) No: EPIQ Ultrasound System System: Transducer: L15-7io Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows: Intended Use: Mode of Operation (includes simultaneous B-mode) Clinical Application Specific Color Combined Other General PWD B M CWD (Track I only) (Tracks i & III) Doppler (Spec.) (Spec.) Ophthalmic Ophthalmic Fetal / OB Abdominal Intra-operative (Cardiac) ನ N N N Note: 1,2,3 Note: 5,8,9,10,11,12,13 ਮ N Note: 1,2,3 Note: 5,8,9,10,11,12,13 Intra-operative (Vascular) N N Fetal Imaging Laparoscopic Note: 5,8,9,10,11,12,13 & Other Pediatric N N N N Note: 1,2,3 Small Organ {breast, thyroid, ਮ N N N Note: 1,2,3 Note: 5,8,10,11,12,13 testicle) Neonatal Cephalic Adult Cephalic Trans-rectal Trans-vaginal Trans-urethral Trans-esoph. (non-Cardiac) Musculo-skel. (Conventional) M N N N Note: 1,2,3 Note: 5,8,9,10,12,13 Note: 5,8,9,10,12,13 Musculo-skel. (Superficial) ನಿ ನ N N Note: 1,2,3 Intra-luminal Other: GYN Other: Urology Cardiac Adult Cardiac Cardiac Pediatric Trans-esophageal (Cardiac) Other (Fetal Echo) Peripheral vessel N N N Note: 1,2,3 Note: 5,8,9,10,11,12,13 Peripheral រោ Vessel Cerebral Vascular N N Note: 1,2,3 Note: 5,8,9,10,11,12,13 N N N= new indication Additional Comments: *Color Doppler includes Color Amplitude Doppler Note 9: Color Power Angio (CPA) Note 1: Combined modes include: 8+PWD; B+Color; B+Amplitude; Note 10: Harmonic Imaging B+M Note 2: Combined modes include: B+M+Color Note 11: Contrast Imaging Note 3: Combined modes include: B+Color+PWD; Note 12: 3D/4D Imaging B+Amplitude+PWD Note 4: Combined modes include: B+CWD; B+Color+CWD; Note 13: XRES B+Amplitude+CWD Note 5: SonoCT Note 14: TDI Note 6: Imaging for guidance of biopsy Note 15: Elastography Note 7: Infertility monitoring of foilicle development Note 16: ElastPQ (for Liver) Note 8: Panoramic Imaging Note 17: PercuNav

{20}------------------------------------------------

EPIQ Diagnostic Ultrasound System

510(k) Premarket Notification

diagnostic ultrasound indications for use statement

510(k) No:System:EPIQ Ultrasound System
Transducer:L18-5
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal / OBNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13
AbdominalNNNNNote: 1,2,3Note:5,6,8,9,10,11,12,13,17
Intra-operative (Cardiac)
Intra-operative (Vascular)
Fetal Imaging& OtherLaparoscopic
PediatricNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13
Small Organ (breast, thyroid,testicle)NNNNNote: 1,2,3Note:5,6,8,9,10,11,12,13,15,17
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)NNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13
Musculo-skel. (Superficial)NNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13
Intra-luminal
Other: GYN
Other: Urology
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (Fetal Echo)
PeripheralVesselPeripheral vesselNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13
Cerebral VascularNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13
N= new indicationAdditional Comments:
*Color Doppler includes Color Amplitude DopplerNote 9: Color Power Angio (CPA)
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude;B+MNote 10: Harmonic Imaging
Note 2: Combined modes include: B+M+ColorNote 11: Contrast Imaging
Note 3: Combined modes include: B+Color+PWD;
B+Amplitude+PWDNote 12: 3D/4D Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD;B+Amplitude+CWDNote 13: XRES
Note 5: SonoCTNote 14: TDI
Note 6: Imaging for guidance of biopsyNote 15: Elastography
Note 7: Infertility monitoring of follicle developmentNote 16: ElastPQ (for Liver)
Note 8: Panoramic ImagingNote 17: PercuNav
510(k) No:
System: EPIQ Ultrasound System
Transducer: S5-1
Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal Imaging& OtherFetal / OBNNNNNNote: 1,2,3Note: 6,8,9,10,12,13, 17
AbdominalNNNNNNote: 1,2,3Note: 6,8,9,10,11,12,13,17
Intra-operative (Cardiac)
Intra-operative (Vascular)
Laparoscopic
PediatricNNNNNNote: 1,2,3Note: 6,8,9,10,11,12,13,17
Small Organ (breast, thyroid, testicle)
Neonatal Cephalic
Adult CephalicNNNNNNote: 1,2,3Note: 8,9,10,11,12,13, 17
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)
Musculo-skel. (Superficial)
Intra-luminal
Other: GYN
Other: Urology
CardiacCardiac AdultNNNNNNote: 1,2,3,4Note: 10,11,12,13,14, 17
Cardiac PediatricNNNNNNote: 1,2,3,4Note: 10,11,12,13,14, 17
Trans-esophageal (Cardiac)
Other (Fetal Echo)NNNNNNote: 1,2,3,4Note: 10,13,14
PeripheralPeripheral vesselNNNNNNote: 1,2,3Note: 6,8,9,10,11,12,13,17
VesselCerebral Vascular
N= new indication
Additional Comments:
*Color Doppler includes Color Amplitude Doppler
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude; B+MNote 9: Color Power Angio (CPA)
Note 2: Combined modes include: B+M+ColorNote 10: Harmonic Imaging
Note 3: Combined modes include: B+Color+PWD;B+Amplitude+PWDNote 11: Contrast Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD;B+Amplitude+CWDNote 12: 3D/4D Imaging
Note 5: SonoCTNote 13: XRES
Note 6: Imaging for guidance of biopsyNote 14: TDI
Note 7: Infertility monitoring of follicle developmentNote 15: Elastography
Note 8: Panoramic ImagingNote 16: ElastPQ (for Liver)
510(k) No:
System:EPIQ Ultrasound System
Transducer:57-3t
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal Imaging& OtherFetal / OB
Abdominal
Intra-operative (Cardiac)
Intra-operative (Vascular)
Laparoscopic
Pediatric
Small Organ (breast, thyroid, testicle)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)
Musculo-skel. (Superficial)
Intra-luminal
Other: GYN
Other: Urology
CardiacCardiac Adult
Cardiac Pediatric
Trans-esophageal (Cardiac)NNNNNNote: 1,2,3,4Note: 10,11,12,13,14
Other (Fetal Echo)
PeripheralVesselPeripheral vessel
Cerebral Vascular
N= new indication
Additional Comments:
*Color Doppler includes Color Amplitude DopplerNote 9: Color Power Angio (CPA)
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude;B+MNote 10: Harmonic Imaging
Note 2: Combined modes include: B+M+ColorNote 11: Contrast Imaging
Note 3: Combined modes include: B+Color+PWD;B+Amplitude+PWDNote 12: 3D/4D Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD;B+Amplitude+CWDNote 13: XRES
Note 5: SonoCTNote 14: TDI
Note 6: Imaging for guidance of biopsyNote 15: Elastography
Note 7: Infertility monitoring of follicle developmentNote 16: ElastPQ (for Liver)
Note 8: Panoramic ImagingNote 17: PercuNav
510(k) No:
System:EPIQ Ultrasound System
Transducer:S8-3
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
General(Track I only)Clinical ApplicationSpecific(Tracks I & III)Mode of Operation (*includes simultaneous B-mode)Combined*(Spec.)Other(Spec.)
BMPWDCWDColorDoppler*
OphthalmicOphthalmic
Fetal / OBNNNNNote: 1,2,3Note: 7,8,10,12,13
Abdominal
Intra-operative (Cardiac)
Intra-operative (Vascular)
Fetal Imaging& OtherLaparoscopic
PediatricNNNNNote: 1,2,3Note: 7,8,10,11,12,13
Small Organ (breast, thyroid, testicle)NNNNNote: 1,2,3Note: 8,10,12,13
Neonatal CephalicNNNNNote: 1,2,3Note: 8,10,12,13
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)
Musculo-skel. (Superficial)
Intra-luminal
Other: GYN
Other: Urology
Cardiac AdultNNNNNNote: 1,2,3,4Note: 10,11,12,13,14
CardiacCardiac PediatricNNNNNNote: 1,2,3,4Note: 10,11,12,13,14
Trans-esophageal (Cardiac)
Other (Fetal Echo)
PeripheralVesselPeripheral vessel
Cerebral Vascular
N= new indication
Additional Comments:
*Color Doppler includes Color Amplitude DopplerNote 9: Color Power Angio (CPA)
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude;B+MNote 10: Harmonic Imaging
Note 2: Combined modes include: B+M+ColorNote 11: Contrast Imaging
Note 3: Combined modes include: B+Color+PWD;B+Amplitude+PWDNote 12: 3D/4D Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD;B+Amplitude+CWDNote 13: XRES
Note 5: SonoCTNote 14: TDI
Note 6: Imaging for guidance of biopsyNote 7: Infertility monitoring of follicle developmentNote 15: ElastographyNote 16: ElastPQ (for Liver)
Note 8: Panoramic ImagingNote 17: PercuNav
Mode of Operation (*includes simultaneous B-mode)
510(k) No:System:Transducer:EPIQ Ultrasound SystemS12-4BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
General(Track I only)Specific(Tracks I & III)
OphthalmicOphthalmic
Fetal Imaging& OtherFetal / OB
Abdominal
Intra-operative (Cardiac)
Intra-operative (Vascular)
Laparoscopic
PediatricNNNNNNote: 1,2,3Note: 8, 10, 11, 12, 13
Small Organ (breast, thyroid, testicle)
Neonatal CephalicNNNNNNote: 1,2,3Note: 8,10,12,13
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)
Musculo-skel. (Superficial)
Intra-luminal
Other: GYN
Other: Urology
CardiacCardiac AdultNNNNNNote: 1,2,3,4Note: 11,12,13,14
Cardiac PediatricNNNN*NNote: 1,2,3,4Note: 11,12,13,14
Trans-esophageal (Cardiac)
Other (Fetal Echo)
PeripheralVesselPeripheral vessel
Cerebral Vascular
N= new indicationAdditional Comments:*Color Doppler includes Color Amplitude Doppler Note 9: Color Power Angio (CPA)Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude; Note 10: Harmonic ImagingB+MNote 2: Combined modes include: B+M+Color Note 11: Contrast ImagingNote 3: Combined modes include: B+Color+PWD; Note 12: 3D/4D ImagingB+Amplitude+PWDNote 4: Combined modes include: B+CWD; B+Color+CWD; Note 13: XRESB+Amplitude+CWDNote 5: SonoCT Note 14: TDINote 6: Imaging for guidance of biopsy Note 15: ElastographyNote 7: Infertility monitoring of follicle development Note 16: ElastPQ (for Liver)Note 8: Panoramic Imaging Note 17: PercuNav
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
GeneralSpecificBMPWDCWDColorDoppler*Combined *(Spec.)Other(Spec.)
(Track I only)(Tracks I & III)
OphthalmicOphthalmic
Fetal / OBNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13
AbdominalNNNNNote: 1,2,3Note: 5,6,8,9,10,11,12,13
Intra-operative (Cardiac)
Intra-operative (Vascular)
Fetal ImagingLaparoscopic
& OtherPediatric
Small Organ (breast, thyroid,
testicle)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)
Musculo-skel. (Superficial)
Intra-luminal
Other: GYN
Other: Urology
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (Fetal Echo)NNNNNote: 1,2,3Note: 5,9,10,11,13
PeripheralPeripheral vessel
VesselCerebral Vascular
N= new indication
Additional Comments:
*Color Doppler includes Color Amplitude DopplerNote 9: Color Power Angio (CPA)
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude;Note 10: Harmonic Imaging
B+M
Note 2: Combined modes include: B+M+ColorNote 11: Contrast Imaging
Note 3: Combined modes include: B+Color+PWD;B+Amplitude+PWDNote 12: 3D/4D Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD;
B+Amplitude+CWDNote 13: XRES
Note 5: SonoCTNote 14: TDI
Note 6: Imaging for guidance of biopsyNote 15: Elastography
Note 7: Infertility monitoring of follicle developmentNote 16: ElastPQ (for Liver)
Note 8: Panoramic ImagingNote 17: PercuNav
510(k) No:System:EPIQ Ultrasound System
Transducer:X5-1
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Mode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal / OB
AbdominalNNNNNote: 1,2,3Note: 8,9,10,11,12,13
Intra-operative (Cardiac)
Intra-operative (Vascular)
Fetal Imaging& OtherLaparoscopic
PediatricNNNNNote: 1,2,3Note: 8,9,10,11,12,13
Small Organ (breast, thyroid, testicle)
Neonatal Cephalic
Adult CephalicNNNNNote: 1,2,3Note: 8,9,10,11,12,13
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)
Musculo-skel. (Superficial)
Intra-luminal
Other: GYN
Other: Urology
Cardiac AdultNNNNNNote: 1,2,3,4Note: 10,11,12,13,14
CardiacCardiac PediatricNNNNNNote: 1,2,3,4Note: 10,11,12,13,14
Trans-esophageal (Cardiac)
Other (Fetal Echo)
PeripheralVesselPeripheral vessel
Cerebral Vascular
N= new indication
Additional Comments:
*Color Doppler includes Color Amplitude Doppler
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude;B+MNote 9: Color Power Angio (CPA)
Note 2: Combined modes include: B+M+ColorNote 10: Harmonic Imaging
Note 3: Combined modes include: B+Color+PWD;B+Amplitude+PWDNote 11: Contrast Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD;B+Amplitude+CWDNote 12: 3D/4D Imaging
Note 5: SonoCTNote 13: XRES
Note 6: Imaging for guidance of biopsyNote 14: TDI
Note 7: Infertility monitoring of follicle developmentNote 15: Elastography
Note 8: Panoramic ImagingNote 16: ElastPQ (for Liver)
Note 17: PercuNav
System:Transducer:EPIQ Ultrasound SystemX6-1
Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:Intended Use:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal Imaging& OtherFetal / OBNNNNNote: 1,2,3Note: 6,8,9,10,12,13
AbdominalNNNNNote: 1,2,3Note: 6,8,9,10,11,12,13,17
Intra-operative (Cardiac)
Intra-operative (Vascular)
Laparoscopic
PediatricNNNNNote: 1,2,3Note:6,8,9,10,11,12,13,17
Small Organ (breast, thyroid,testicle)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)
Musculo-skel. (Superficial)
Intra-luminal
Other: GYNNNNNNote: 1,2,3Note: 6,8,9,10,11,12,13
Other: Urology
CardiacCardiac Adult
Cardiac Pediatric
Trans-esophageal (Cardiac)
Other (Fetal Echo)
PeripheralVesselPeripheral vesselNNNNNote: 1,2,3Note: 6,8,9,10,11,12,13,17
Cerebral VascularNNNNNote: 1,2,3Note: 6,8,9,10,11,12,13,17
N= new indication
Additional Comments:
*Color Doppler includes Color Amplitude DopplerNote 9: Color Power Angio (CPA)
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude;B+MNote 10: Harmonic Imaging
Note 2: Combined modes include: B+M+ColorNote 11: Contrast Imaging
Note 3: Combined modes include: B+Color+PWD;
B+Amplitude+PWDNote 12: 3D/4D Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD;Note 13: XRES
B+Amplitude+CWD
Note 5: SonoCTNote 14: TDI
Note 6: Imaging for guidance of biopsyNote 15: Elastography
Note 7: Infertility monitoring of follicle developmentNote 16: ElastPQ (for Liver)
Note 8: Panoramic ImagingNote 17: PercuNav

{21}------------------------------------------------

{22}------------------------------------------------

{23}------------------------------------------------

{24}------------------------------------------------

:

{25}------------------------------------------------

510(k) No:
System:EPIQ Ultrasound System
Transducer:V6-2
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

{26}------------------------------------------------

{27}------------------------------------------------

510(k) No: ___________________________________________________________________________________________________________________________________________________________________

DIAGNOSTIC ULTRASOUND INDICATIONS FOR USE STATEMENT

{28}------------------------------------------------

510(k) No:
System:EPIQ Ultrasound System
Transducer:X7-2t
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks 1 & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal Imaging& OtherFetal / OB
Abdominal
Intra-operative (Cardiac)
Intra-operative (Vascular)
Laparoscopic
Pediatric
Small Organ (breast, thyroid, testicle)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Conventional)
Musculo-skel. (Superficial)
Intra-luminal
Other: GYN
Other: Urology
CardiacCardiac Adult
Cardiac Pediatric
Trans-esophageal (Cardiac)NNNNNNote: 1,2,3,4Note: 10,11,12,13,14
Other (Fetal Echo)
PeripheralVesselPeripheral vessel
Cerebral Vascular
N= new indication
Additional Comments:
*Color Doppler includes Color Amplitude DopplerNote 9: Color Power Angio (CPA)
Note 1: Combined modes include: B+PWD; B+Color; B+Amplitude; B+MNote 10: Harmonic Imaging
Note 2: Combined modes include: B+M+ColorNote 11: Contrast Imaging
Note 3: Combined modes include: B+Color+PWD; B+Amplitude+PWDNote 12: 3D/4D Imaging
Note 4: Combined modes include: B+CWD; B+Color+CWD; B+Amplitude+CWDNote 13: XRES
Note 5: SonoCTNote 14: TDI
Note 6: Imaging for guidance of biopsyNote 15: Elastography
Note 7: Infertility monitoring of follicle developmentNote 16: ElastPQ (for Liver)
Note 8: Panoramic ImagingNote 17: PercuNav

§ 892.1550 Ultrasonic pulsed doppler imaging system.

(a)
Identification. An ultrasonic pulsed doppler imaging system is a device that combines the features of continuous wave doppler-effect technology with pulsed-echo effect technology and is intended to determine stationary body tissue characteristics, such as depth or location of tissue interfaces or dynamic tissue characteristics such as velocity of blood or tissue motion. This generic type of device may include signal analysis and display equipment, patient and equipment supports, component parts, and accessories.(b)
Classification. Class II.