K Number
K123616
Date Cleared
2012-12-21

(28 days)

Product Code
Regulation Number
892.1560
Reference & Predicate Devices
Predicate For
N/A
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

The A6 Portable Ultrasonic Diagnostic System with added transducer is a general-purpose ultrasonic imaging instrument intended for use by a qualified physician for evaluation of Abdomen, Cardiac, Small Organ (Thyroid, parathyroid, submaxillar, gland, testes and breast.), Peripheral Vascular, Trans-vaginal, Trans-rectal, Musculo-skeletal (Conventional and Superficial), Pediatric, Fetal, OB/Gyn and Urology. This device is intended to adult, pregnant woman, pediatric, and neonate.

Device Description

The A6 Portable Ultrasonic Diagnostic System with added transducer is a general purpose, portable, software controlled and ultrasound diagnostic system. This ultrasonic device is designed to project ultrasound waves into body tissue and to present the returned echo information on the monitor. The resulting information is displayed in B-Mode, M-Mode and THI- Mode or in the combined mode (i.e. B/M-Mode). This system is a Track I device that employs an array of probes that include linear array and convex linear array with a frequency range of approximately 2.0 MHz to 12 MHz.

AI/ML Overview

The provided 510(k) K123616 submission for the SonoScape A6 Portable Ultrasonic Diagnostic System and its associated transducers concerns a traditional substantial equivalence determination. This type of submission relies on demonstrating that the new device is as safe and effective as a legally marketed predicate device, often by showing it has the same technological characteristics and intended use, or that any differences do not raise new questions of safety or effectiveness.

Crucially, this document explicitly states: "No clinical testing was required." This means there was no study performed to directly test the diagnostic performance of the device against a set of acceptance criteria in a clinical setting. The acceptance criteria for this device are primarily related to meeting established medical device safety and performance standards for ultrasound systems, rather than diagnostic accuracy metrics like sensitivity or specificity.

Therefore, many of the requested points below about specific study details (like sample size for test sets, number of experts, adjudication methods, MRMC studies, or standalone performance) cannot be answered from this document because such clinical performance studies were not conducted.

Here's a breakdown of the information that can be extracted or inferred from the provided text, particularly in the context of device acceptance:


1. Table of Acceptance Criteria and Reported Device Performance

For this type of traditional 510(k), acceptance criteria are typically met by adherence to recognized standards and by demonstrating that the device functions according to its technical specifications and intended use without raising new safety or effectiveness concerns compared to the predicate. The "reported device performance" is essentially that it meets these standards and functions as intended, similar to the predicate.

Acceptance Criteria CategorySpecific Criteria / Standard MetReported Device Performance
Safety and Effectiveness (General)Substantial Equivalence to Predicate Device (SonoScape A6, K101337)The device is determined to be Substantially Equivalent (SE) to the predicate device in respect of safety and effectiveness.
Technological CharacteristicsSame fundamental technology as the predicate device.The A6 Portable Ultrasonic Diagnostic System with added transducer incorporates the same fundamental technology as the predicate device.
Acoustic Output MeasurementsNEMA UD 2 Acoustic Output Measurement Standard for Diagnostic Ultrasound Equipment: 2004Acoustic output is measured and calculated per NEMA UD 2 Acoustic Output Measurement Standard for Diagnostic Ultrasound Equipment: 2004. All transducers used with the A6 are track 1 (meaning their acoustic output is within specified Track 1 limits).
Electrical, Thermal, Mechanical SafetyIEC 60601-1: 2005 (General Requirements for Safety), IEC 60601-1-2: 2007 (EMC), IEC 60601-2-37: 2008 (Specific for Ultrasonic Equipment)The device has been found to conform to applicable medical device safety standards in regards to thermal, mechanical and electrical safety.
BiocompatibilityImplied standard for patient contact materials.All patient contact materials are biocompatible.
Design SpecificationsInternal design specifications for the device and added transducers.Laboratory testing was conducted to verify that the A6 Portable Ultrasonic Diagnostic System with added transducer met all design specification.
Intended UseConsistent with predicate device's intended use across various anatomical regions and patient populations.The intended uses for the system and each transducer (Abdomen, Cardiac, Small Organ, Peripheral Vascular, Transvaginal, Transrectal, Musculo-skeletal, Pediatric, Fetal, OB/Gyn and Urology for adult, pregnant woman, pediatric, and neonate) are considered substantially equivalent to the predicate.

2. Sample size used for the test set and the data provenance (e.g. country of origin of the data, retrospective or prospective)

  • Not applicable / No specific clinical test set: The submission explicitly states, "No clinical testing was required." The acceptance was based on engineering and performance verification against recognized standards and comparison to a predicate device, not on diagnostic performance in a test set of patient data.

3. Number of experts used to establish the ground truth for the test set and the qualifications of those experts (e.g. radiologist with 10 years of experience)

  • Not applicable: As no clinical testing was required, there was no test set requiring ground truth established by experts.

4. Adjudication method (e.g. 2+1, 3+1, none) for the test set

  • Not applicable: As no clinical testing was required, there was no test set requiring adjudication.

5. If a multi-reader multi-case (MRMC) comparative effectiveness study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

  • No: This was not a comparative effectiveness study involving human readers or AI. It's a 510(k) for an ultrasound system, comparing it to a previous version of the same system.

6. If a standalone (i.e. algorithm only without human-in-the-loop performance) was done

  • No: The device is an ultrasonic diagnostic system, requiring a human operator (qualified physician) for its intended use. It is not an algorithm for standalone diagnostic performance.

7. The type of ground truth used (expert consensus, pathology, outcomes data, etc.)

  • No clinical ground truth used: For the purposes of this 510(k), ground truth was established by adherence to technical specifications, engineering measurements against industry standards (e.g., NEMA UD 2, IEC 60601 series), and verification that the device's technical characteristics and intended use were substantially equivalent to the predicate device.

8. The sample size for the training set

  • Not applicable: As no clinical testing was required and this is not an AI/algorithm-based submission, there was no training set in the conventional sense for diagnostic performance.

9. How the ground truth for the training set was established

  • Not applicable: No training set was used.

{0}------------------------------------------------

K123616

SonoScape Company LTD

A6 Portable Ultrasonic Diagnostic System

Tab 4 510(k) Summary

DEC 2 1 2012

This summary of 510(k) safety and effectiveness information is being submitted in accordance with the requirements of SMDA 1990 and 21 CFR §807.92

The assigned 510(k) number:

Date of submission: November 15, 2012

Submitter:

SonoScape Company Limited

Address: 4F, Yizhe Building, Yuquan Road, Nanshan, Shenzhen 518051, P.R.China

Tel: (86) 755-26722890

Fax: (86) 755-26722850

Contact Person: Zhou Wenping

Submission Correspondent:

Ms. Diana Hong & Mr. Lee Fu

Mid-Link Consulting Co., Ltd

P.O. Box 237-023, Shanghai, 200237, China

Tel: +86-21-22815850

Fax: 240-238-7587

Email: info@mid-link.net

Proposed Device Identification:

  • Trade/Proprietary Name: A6 Portable Ultrasonic Diagnostic System

  • Common Name: Diagnostic Ultrasound System and Transducers

  • Classification:

Regulatory Class: II

21 CFR 892.1560 Ultrasonic Pulsed Echo Imaging System(90-IYO)

.

510(k) Summary

{1}------------------------------------------------

21 CFR 892.1570 Diagnostic Ultrasound Transducer(90-ITX)

Legally Marketed Predicate Device:

SonoScape A6 Portable Ultrasonic Diagnostic System 510(k) Number: K101337

Description:

The A6 Portable Ultrasonic Diagnostic System with added transducer is a general purpose, portable, software controlled and ultrasound diagnostic system. This ultrasonic device is designed to project ultrasound waves into body tissue and to present the returned echo information on the monitor. The resulting information is displayed in B-Mode, M-Mode and THI- Mode or in the combined mode (i.e. B/M-Mode). This system is a Track I device that employs an array of probes that include linear array and convex linear array with a frequency range of approximately 2.0 MHz to 12 MHz.

Intended Use Statement:

The A6 Portable Ultrasonic Diagnostic System with added transducer is a general-purpose ultrasonic imaging instrument intended for use by a qualified physician for evaluation of t Abdomen, Cardiac, Small Organ (Thyroid, parathyroid, parotid, submaxillary gland, testes and breast.), Peripheral Vascular, Transvaginal, Transrectal, Musculo-skeletal (Conventional and Superficial), Pediatric, Fetal, OB/Gyn and Urology. This device is intended to adult, pregnant woman, pediatric, and neonate.

Technological Characteristics:

The A6 Portable Ultrasonic Diagnostic System with added transducer incorporates the same fundamental technology as the predicate device. The device has been tested as Track 1 Device per the FDA Guidance document "Information for Manufacturers Secking Marketing Clearance of Diagnostic Ultrasound Systems and Transducers" issued September 9, 2008. The acoustic output is measured and calculated per NEMA UD 2 Acoustic Output Measurement Standard for Diagnostic Ultrasound Equipment: 2004. All transducers used with the A6 Portable Ultrasonic Diagnostic System are track 1. All patient contact materials

: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

510(k) Summary

{2}------------------------------------------------

are biocompatible. The technology characteristics of the A6 Portable Ultrasonic Diagnostic System with these modifications do not affect the safety or efficacy of the device.

Testing:

Laboratory testing was conducted to verify that the A6 Portable Ultrasonic Diagnostic

System with added transducer met all design specification and was substantially equivalent :: : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : to the Predicate Device. The device has been found to conform to applicable medical device safety standards in regards to thermal, mechanical and electrical safety as well as :: : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : biocompatibility. Acoustic output is measured and calculated according to "Acoustic Output Measuring Standard for Diagnostic Ultrasound Equipment". .....

IEC 60601-1; 2005 Medical Electrical Equipment - Part 1: General Requirements for Safety IEC 60601-1-2: 2007 Medical Electrical Equipment - Part 1-2: General Requirements for Safety - Collateral Standard: Electromagnetic Compatibility -- Requirements and Tests. IEC 60601-2-37: 2008 Medical electrical equipment -- Part 2-37: Particular requirements for the basic safety and essential performance of ultrasonic medical diagnostic and monitoring i ..:.... ::::: . . . . . . . ... : .. .. equipment.

NEMA UD 2-2004, Acoustic Output Measurement Standard for Diagnostic Ultrasound Equipment Version 3.

Clinical Test:

No clinical testing was required.

Substantially Equivalent Conclusion

The proposed device, A6 Portable Ultrasonic Diagnostic System, is determined to be Substantially Equivalent (SE) to the predicate device in respect of safety and effectiveness.

510(k) Summary

{3}------------------------------------------------

DEPARTMENT OF HEALTH & HUMAN SERVICES

Image /page/3/Picture/1 description: The image is a black and white seal for the Department of Health & Human Services - USA. The seal is circular with the text "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" arranged around the perimeter. In the center of the seal is an abstract symbol that resembles an eagle or bird-like figure with stylized wings.

Public Health Service

Food and Drug Administration 10903 New Hampshire Avenue Document Control Center - WO66-G609 Silver Spring, MD 20993-002

SonoScape Company Limited % Ms. Diana Hong & Mr. Lee Fu General Manager Mid-Link Consulting Co., Ltd. P.O. Box 237-023, Shanghai, 200237 CHINA

DEC 2 1 2012

Re: K123616.

Trade/Device Name: Portable Ultrasonic Diagnostic System Regulation Number: 21 CFR 892.1560 Regulation Name: Ultrasonic pulsed echo imaging system Regulatory Class: II Product Code: IYO and ITX Dated: November 23, 2012 Received: November 23, 2012

Dear Ms. Hong:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and we have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

This determination of substantial equivalence applies to the following transducers intended for use with the Portable Ultrasonic Diagnostic System, as described in your premarket notification:

Transducer Model Number

6V4 Micro-curved Array 6V5 Micro-curved Array EC2 Micro-curved Array BCC9-4 Micro-curved Array C612 Micro-curved Array C312 Micro-curved Array

C351 Curved Array C352 Curved Array C543 Curved Array L745 Linear Array L746 Linear Array

{4}------------------------------------------------

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 895. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

This letter will allow you to begin marketing your device as described in your premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus permits your device to proceed to market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please go to http://www.fda.gov/AboutFDA/CentersOffices/CDRH/CDRHOffices/ucm115809.htm for the Center for Devices and Radiological Health's (CDRH's) Office of Compliance. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to

http://www.fda.gov/MedicalDevices/Safety/ReportaProblem/default.htm for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance.

If you have any questions regarding the content of this letter, please contact Shahram Vaezy at (301) 796-6242.

Sincerely yours,

Janine M. Morris

Director Division of Radiological Health Office of In Vitro Diagnostics and Radiological Health Center for Devices and Radiological Health

Enclosure(s)

{5}------------------------------------------------

Tab 2 Indications for Use

510(k) Number: K123616

Device Name: Portable Ultrasonic Diagnostic System ·

Indications for Use:

The A6 Portable Ultrasonic Diagnostic System with added transducer is a general-purpose ultrasonic imaging instrument intended for use by a qualified physician for evaluation of Abdomen, Cardiac, Small Organ (Thyroid, parathyroid, submaxillar, gland, testes Vascular, Trans-vaginal, Trans-rectal, Musculo-skeletal and breast.), Peripheral (Conventional and Superficial), Pediatric, Fetal, OB/Gyn and Urology. This device is intended to adult, pregnant woman, pediatric, and neonate.

Prescription Use (Part 21 CFR 801 Subpart D) AND/OR

Over-The-Counter Use (21 CFR 807 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LANE-CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of In Vitro Diagnostics and Radiological Health (OIR)

(Division Sign Off)
Division of Radiological Health
Office of In Vitro Diagnostic and Radiological Health
510(k) K123616

Tab 2 Indications for use

{6}------------------------------------------------

System: SonoScape A6 Diagnostic Ultrasound Pulsed Echo System

Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

General(TRACK 1ONLY)Specific(TRACKS 1 & 3)Mode of OperationOther*
BMPWDCWDColorDopplerPower(Amplitude)DopplerCombinedSpecify
OphthalmicOphthalmic
FetalImaging&OtherFetalAbdominalPPNote 1Note 2
Intra-operative Specify
Intra-operative Neuro
Laparoscopic
PediatricPPNote 1Note 2
Small Organ (specify)PPNote 1Note 2,3
Neonatal Cephalic
Adult Cephalic
Trans-rectalPPNote 1Note 2
Trans-vaginalPPNote 1Note 2
Trans-urethral
Trans-esoph.(non-Card)
Musculo-skeletal(Conventional)PPNote 1Note 2
Musculo-skeletal(Superficial)PPNote 1Note 2
Intravascular
Other (Urology)PPNote 1Note 2
Other (Ob/GYN)PPNote 1Note 2
CardiacCardiac AdultPPNote 1Note 2
Cardiac PediatricPPNote 1Note 2
Intravascular(Cardiac)
Trans-esoph.(Cardiac)
Intra-cardiac
Other (specify)
PeripheralVesselPeripheral vesselPPNote 1Note 2

N = new indication;

Note 1: B/M

Note 2: THI (Tissue Harmonic Imaging). The feature does not use contrast agents.

Note 3: Small Organ (Thyroid, parathyroid, parotid, submaxillary gland, testes and breast.)

(Division Sign Off)

Division of Radiological Health

Tab 2 Indications for use

Office of In Vitro Diagnostics and Radiological Health

510(K) K123616

{7}------------------------------------------------

6V4 Micro-curved Array Transducer: Diagnostic Ultrasound Transducer

Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Clinical ApplicationMode of Operation
General(TRACK 1ONLY)Specific(TRACKS 1 & 3)BMPWDCWDColorDopplerPower(Amplitude)DopplerOther*CombinedOther*Specify
OphthalmicOphthalmic
FetalImaging&OtherFetal
Abdominal
Intra-operative Specify
Intra-operative Neuro
Laparoscopic
Pediatric
Small Organ (specify)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginalPPNote 1Note 2
Trans-urethral
Trans-esoph.(non-Card)
Musculo-skeletal(Conventional)
Musculo-skeletal(Superficial)
Intravascular
Other (Urology)
Other (Ob/GYN)PPNote 1Note 2
CardiacCardiac Adult
Cardiac Pediatric
Intravascular(Cardiac)
Trans-esoph.(Cardiac)
Intra-cardiac
Other (specify)
PeripheralVesselPeripheral vessel
Other (specify)

N = new indication;

P = previously cleared by FDA;

E = added under this appendix

Note 1: B/M

Note 2: THI (Tissue Harmonic Imaging). The feature does not use contrast agents. Note 3: Small Organ (Thyroid, parathyroid, parotid, submaxillary gland, testes and breast.)

Sammy Thomas
(Division Sign Off)

Division of Radiological Health

Office of In Vitro Diagnostics and Radiological Health

510(k) K123616

{8}------------------------------------------------

6V5 Micro-curved Array Transducer: Diagnostic Ultrasound Transducer

Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Clinical ApplicationMode of Operation
General(TRACK 1.ONLY)Specific(TRACKS 1 & 3)BMPWDCWDColorDopplerPower(Amplitude)DopplerOther*CombinedOther*Specify
OphthalmicOphthalmic
FetalImaging&OtherFetal
Abdominal
Intra-operative Specify
Intra-operative Neuro
Laparoscopic
Pediatric
Small Organ (specify)
Neonatal Cephalic
Adult Cephalic
Trans-rectalPPNote 1Note 2
Trans-vaginalPPNote 1Note 2
Trans-urethral
Trans-esoph.(non-Card)
Musculo-skeletal(Conventional)
Musculo-skeletal(Superficial)
Intravascular
Other (Urology)PPNote 1Note 2
Other (Ob/GYN)PPNote 1Note 2
CardiacCardiac Adult
Cardiac Pediatric
Intravascular(Cardiac)
Trans-esoph.(Cardiac)
Intra-cardiac
Other (specify)
PeripheralVesselPeripheral vessel
Other (specify)

N = new indication;

P = previously cleared by FDA;

E = added under this appendix

Note 1: B/M

Note 2: THI (Tissue Harmonic Imaging). The feature does not use contrast agents.

Note 3: Small Organ (Thyroid, parathyroid, parotid, submaxillary gland, testes and breast.)

(Division Sign Off)

Division of Radiological Health

Office of In Vitro Diagnostics and R

2-4

510(k) K123616

{9}------------------------------------------------

Transducer: EC2 Micro-curved Array Diagnostic Ultrasound Transducer

Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Clinical ApplicationMode of OperationOther*
General(TRACK 1ONLY)Specific(TRACKS 1 & 3)BMPWDCWDColorDopplerPower(Amplitude)DopplerCombinedSpecify
OphthalmicOphthalmic
FetalImaging&OtherFetal
Abdominal
Intra-operative Specify
Intra-operative Neuro
Laparoscopic
Pediatric
Small Organ (specify)
Neonatal Cephalic
Adult Cephalic
Trans-rectalPPNote 1Note 2
Trans-vaginalPPNote 1Note 2
Trans-urethral
Trans-esoph.(non-Card)
Musculo-skeletal(Conventional)
Musculo-skeletal(Superficial)
Intravascular
Other (Urology)PPNote 1Note 2
Other (Ob/GYN)PPNote 1Note 2
CardiacCardiac Adult
Cardiac Pediatric
Intravascular(Cardiac)
Trans-esoph. (Cardiac)
Intra-cardiac
Other (specify)
PeripheralVesselPeripheral vessel
Other (specify)

N = new indication;

P = previously cleared by FDA;

E = added under this appendix

Note 1: B/M

Note 2: THI (Tissue Harmonic Imaging). The feature does not use contrast agents.

Note 3: Small Organ (Thyroid, parathyroid, parotid, submaxillary gland, testes and breast.)

(Division Sign Off)

Division of Radiological Health

Indications for use

Office of In Vitro Diagnostics and Radiological Health

510(k) K123616

{10}------------------------------------------------

BCC9-4 Micro-curved Array Transducer: Diagnostic Ultrasound Transducer

Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Clinical ApplicationMode of Operation
General(TRACK 1ONLY)Specific(TRACKS 1 & 3)BMPWDCWDColorDopplerPower(Amplitude)DopplerOther*CombinedOther*Specify
OphthalmicOphthalmic
FetalImaging&OtherFetalAbdominalIntra-operative SpecifyIntra-operative NeuroLaparoscopicPediatricSmall Organ (specify)Neonatal CephalicAdult Cephalic
Trans-rectalPPNote 1Note 2
Trans-vaginalPPNote 1Note 2
Trans-urethral
Trans-esoph.(non-Card)
Musculo-skeletal(Conventional)
Musculo-skeletal(Superficial)
Intravascular
Other (Urology)PPNote 1Note 2
Other (Ob/GYN)PPNote 1Note 2
CardiacCardiac Adult
Cardiac Pediatric
Intravascular(Cardiac)
Trans-esoph.(Cardiac)
Intra-cardiac
Other (specify)
PeripheralVesselPeripheral vessel
Other (specify)

N = new indication;

P = previously cleared by FDA;

E = added under this appendix

Note 1: B/M

Note 2: THI (Tissue Harmonic Imaging). The feature does not use contrast agents. Note 3: Small Organ (Thyroid, parathyroid, parotid, submaxillary gland, testes and breast.)

(Division Sign Off)

Division of Radiological Health

Indications for use

Office of In Vitro Diagnostics and Radiological Health

510(k) K123616

{11}------------------------------------------------

C612 Micro-curved Array Transducer: Diagnostic Ultrasound Transducer

Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Clinical ApplicationMode of Operation
General(TRACK 1ONLY)Specific(TRACKS 1 & 3)BMPWDCWDColorDopplerPower(Amplitude)DopplerOther*CombinedOther*Specify
OphthalmicOphthalmic
FetalImaging&OtherFetalAbdominalPPNote 1Note 2
Intra-operative SpecifyIntra-operative Neuro
LaparoscopicPediatricSmall Organ (specify)PPNote 1Note 2
Neonatal CephalicAdult Cephalic
Trans-rectalTrans-vaginal
Trans-urethralTrans-esoph.(non-Card)
Musculo-skeletal(Conventional)
Musculo-skeletal(Superficial)
IntravascularOther (Urology)Other (Ob/GYN)
CardiacCardiac AdultCardiac PediatricPPNote 1Note 2
Intravascular(Cardiac)
Trans-esoph.(Cardiac)Intra-cardiacOther (specify)
PeripheralVesselPeripheral vessel
Other (specify)

N = new indication;

P = previously cleared by FDA;

E ▼ added under this appendix

Note 1: B/M

Note 2: THI (Tissue Harmonic Imaging). The feature does not use contrast agents. Note 3: Small Organ (Thyroid, parathyroid, parotid, submaxillary gland, testes and breast.)

(Division Sign Off)

Indications for use

Division of Radiological Health ാനിറേ of In Vitro Diagnostics and Radiological Health

510(k) K123616

{12}------------------------------------------------

C312 Micro-curved Array Transducer: Diagnostic Ultrasound Transducer

Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Clinical ApplicationMode of Operation
General(TRACK 1ONLY)Specific(TRACKS 1 & 3)BMPWDCWDColorDopplerPower(Amplitude)DopplerOther*CombinedOther*Specify
OphthalmicOphthalmic
FetalImaging&OtherFetalAbdominalIntra-operative SpecifyIntra-operative NeuroLaparoscopicPediatricSmall Organ (specify)Neonatal CephalicAdult CephalicTrans-rectalTrans-vaginalTrans-urethralTrans-esoph.(non-Card)Musculo-skeletal(Conventional)Musculo-skeletal(Superficial)IntravascularOther (Urology)Other (Ob/GYN)
CardiacCardiac AdultCardiac PediatricIntravascular(Cardiac)Trans-esoph. (Cardiac)Intra-cardiacOther (specify)PPPNote 1Note 2
PeripheralVesselPeripheral vesselOther (specify)

N = new indication;

P = previously cleared by FDA;

E = added under this appendix

Note 1: B/M

Note 2: THI (Tissue Harmonic Imaging). The feature does not use contrast agents. Note 3: Small Organ (Thyroid, parathyroid, parotid, submaxillary gland, testes and breast.)

Sam Thain
(Division Sign Off)

Division of Radiological Health

Office of in Vitro Diagnostics and

510(k) K123616

{13}------------------------------------------------

Transducer: C351 Curved Array Diagnostic Ultrasound Transducer

Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Clinical ApplicationMode of Operation
General(TRACK 1ONLY)Specific(TRACKS 1 & 3)BMPWDCWDColorDopplerPower(Amplitude)DopplerOther*CombinedOther*Specify
OphthalmicOphthalmic
FetalImaging&OtherFetalPPNote 1Note 2
AbdominalPPNote 1Note 2
Intra-operative Specify
Intra-operative Neuro
Laparoscopic
Pediatric
Small Organ (specify)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph.(non-Card)
Musculo-skeletal(Conventional)
Musculo-skeletal(Superficial)
Intravascular
Other (Urology)PPNote 1Note 2
Other (Ob/GYN)PPNote 1Note 2
CardiacCardiac Adult
Cardiac Pediatric
Intravascular(Cardiac)
Trans-esoph. (Cardiac)
Intra-cardiac
Other (specify)
PeripheralVesselPeripheral vessel
Other (specify)

N = new indication;

P = previously cleared by FDA;

E = added under this appendix

Note 1: B/M

Note 2: THI (Tissue Harmonic Imaging). The feature does not use contrast agents. Note 3: Small Organ (Thyroid, parathyroid, parotid, submaxillary gland, testes and breast.)

Danu Than
(Division Sign Off)

Division of Radiological Health

Office of In Vitro Diagnostics and Radiolo

510(k) K123616

2-9

{14}------------------------------------------------

C352 Curved Array Transducer: Diagnostic Ultrasound Transducer

Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Clinical ApplicationMode of Operation
General(TRACK 1ONLY)Specific(TRACKS 1 & 3)BMPWDCWDColorDoppler.Power(Amplitude)DopplerOther*CombinedOther*Specify
OphthalmicOphthalmic
FetalImaging&OtherFetalAbdominalPPPPNote 1Note 1Note 2Note 2
LaparoscopicPediatricSmall Organ (specify)Neonatal CephalicAdult CephalicTrans-rectalTrans-vaginalTrans-urethralTrans-esoph.(non-Card)Musculo-skeletal(Conventional)Musculo-skeletal(Superficial)Intravascular
Other (Urology)Other (Ob/GYN)PPPPNote 1Note 1Note 2Note 2
CardiacCardiac AdultCardiac PediatricIntravascular(Cardiac)Trans-esoph.(Cardiac)Intra-cardiacOther (specify)
PeripheralVesselPeripheral vesselOther (specify)

N = new indication;

P = previously cleared by FDA;

E = added under this appendix

Note 1: B/M

Note 2: THI (Tissue Harmonic Imaging). The feature does not use contrast agents. Note 3: Small Organ (Thyroid, parathyroid, parotid, submaxillary gland, testes and breast.)

(Division Sign Off)

Division of Radiological Health

Office of In Vitro Diagnostics and Radio

510(k) K123616

2-10

{15}------------------------------------------------

C543 Curved Array Transducer: Diagnostic Ultrasound Transducer

Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Clinical ApplicationMode of Operation
General(TRACK 1ONLY)Specific(TRACKS 1 & 3)BMPWDCWDColorDopplerPower(Amplitude)DopplerOther*CombinedOther*Specify
OphthalmicOphthalmic
FetalImaging&OtherFetal
AbdominalPPNote 1Note 2
Intra-operative Specify
Intra-operative Neuro
Laparoscopic
PediatricPPNote 1Note 2
Small Organ (specify)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph.(non-Card)
Musculo-skeletal(Conventional)
Musculo-skeletal(Superficial)
CardiacIntravascular
Other (Urology)
Other (Ob/GYN)
Cardiac Adult
Cardiac Pediatric
Intravascular(Cardiac)
Trans-esoph. (Cardiac)
Intra-cardiac
PeripheralVesselOther (specify)
Peripheral vessel
Other (specify)

N = new indication; P = previously cleared by FDA; E = added under this appendix

Note 1: B/M

Note 2: THI (Tissue Harmonic Imaging). The feature does not use contrast agents. Note 3: Small Organ (Thyroid, parathyroid, parotid, submaxillary gland, testes and breast.)

Dan Thom
(Division Sign Off)

División of Radiological Health

Office of In Vitro Diagnostics and Radiological

510(k) K123616

Indications for use

{16}------------------------------------------------

L745 Linear Array Transducer: Diagnostic Ultrasound Transducer

Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Clinical ApplicationMode of Operation
General(TRACK 1ONLY)Specific(TRACKS 1 & 3)BMPWDCWDColorDopplerPower(Amplitude)DopplerOther*CombinedOther*Specify
OphthalmicOphthalmic
FetalImaging&OtherFetal
Abdominal
Intra-operative Specify
Intra-operative Neuro
Laparoscopic
Pediatric
Small Organ (specify)PPPNote 1Note 2,3
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph.(non-Card)
Musculo-skeletal(Conventional)PPPNote 1Note 2
Musculo-skeletal(Superficial)PPPNote 1Note 2
Intravascular
Other (Urology)
Other (Ob/GYN)
CardiacCardiac Adult
Cardiac Pediatric
Intravascular(Cardiac)
Trans-esoph. (Cardiac)
Intra-cardiac
Other (specify)
PeripheralVesselPeripheral vesselPPPNote 1
Other (specify)

N = new indication;

P = previously cleared by FDA;

E = added under this appendix

Note 1: B/M

Note 2: THI (Tissue Harmonic Imaging). The feature does not use contrast agents. Note 3: Small Organ (Thyroid, parathyroid, parotid, submaxillary gland, testes and breast.)

(Division Sign Off)

Division of Radiological Hea

Office of In Vitro Diagnostics and Radio

510(k) K123616

2-12

{17}------------------------------------------------

L746 Linear Array Transducer: Diagnostic Ultrasound Transducer

Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Clinical ApplicationMode of Operation
General(TRACK 1ONLY)Specific(TRACKS 1 & 3)BMPWDCWDColorDopplerPower(Amplitude)DopplerOther*CombinedOther*Specify
OphthalmicOphthalmic
FetalImaging&OtherFetal
Abdominal
Intra-operative Specify
Intra-operative Neuro
Laparoscopic
Pediatric
Small Organ (specify)PPPNote 1Note 2,3
Neonatal Cephalic
Adult Cephalic
Trans-rectalTrans-vaginalTrans-urethralTrans-esoph.(non-Card)Musculo-skeletal(Conventional)Musculo-skeletal(Superficial)IntravascularOther (Urology)Other (Ob/GYN)PPPPNote 1Note 1Note 2Note 2
CardiacCardiac AdultCardiac PediatricIntravascular(Cardiac)Trans-esoph.(Cardiac)Intra-cardiacOther (specify)
PeripheralVesselPeripheral vesselPPNote 1Note 2
Other (specify)

N = new indication;

P = previously cleared by FDA;

.......

E = added under this appendix

Note 1: B/M

Note 2: THI (Tissue Harmonic Imaging). The feature does not use contrast agents. Note 3: Small Organ (Thyroid, parathyroid, parotid, submaxillary gland, testes and breast.)

(Division Sign Off)

Division of Radiological Heatth

Office of In Vitro Diagnostics and Radiological

Indications for use

-510(k) K123616

§ 892.1560 Ultrasonic pulsed echo imaging system.

(a)
Identification. An ultrasonic pulsed echo imaging system is a device intended to project a pulsed sound beam into body tissue to determine the depth or location of the tissue interfaces and to measure the duration of an acoustic pulse from the transmitter to the tissue interface and back to the receiver. This generic type of device may include signal analysis and display equipment, patient and equipment supports, component parts, and accessories.(b)
Classification. Class II (special controls). A biopsy needle guide kit intended for use with an ultrasonic pulsed echo imaging system only is exempt from the premarket notification procedures in subpart E of part 807 of this chapter subject to the limitations in § 892.9.