K Number
K111910
Device Name
GLADIATOR HIP STEM
Date Cleared
2011-10-14

(101 days)

Product Code
Regulation Number
888.3330
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
The Gladiator Hip Stems are intended for use in uncemented total hip arthroplasty for reduction or relief of pain and/or improved hip function in skeletally mature patients. Indications for Use: 1. non-inflammatory degenerative joint disease such as osteoarthritis, avascular necrosis, ankylosis, protrusio acetabuli, and painful hip dysplasia; 2. inflammatory degenerative joint disease such as rheumatoid arthritis; 3. correction of functional deformity; and, 4. revision procedures where other treatments or devices have failed. The Gladiator cpTi Plasma Sprayed hip stem is intended for cementless hip arthroplasty. The Cemented hip stem is intended for cemented hip arthroplasty.
Device Description
The Gladiator stems are modular hip stems that couple with modular necks. Design features of the stems are summarized below: - Cementless stem with proximal cpTi plasma spray coating. - Available in 10 sizes - Manufactured from Ti alloy - Cemented - Available in 5 sizes - Manufactured from CoCr alloy - Distal centralizers available
More Information

Not Found

No
The summary describes a mechanical implant (hip stem) and its physical properties and testing. There is no mention of software, algorithms, or data processing that would indicate the use of AI/ML.

Yes
The device is intended for use in total hip arthroplasty to reduce or relieve pain and improve hip function, addressing conditions like degenerative joint disease and functional deformity.

No

The device is a hip stem intended for use in total hip arthroplasty to replace or improve hip function, not to diagnose a condition.

No

The device description clearly outlines physical components made of Ti alloy and CoCr alloy, intended for surgical implantation. There is no mention of software as the primary or sole component.

No, this device is not an IVD (In Vitro Diagnostic).

Here's why:

  • IVD Definition: In Vitro Diagnostics are medical devices used to perform tests on samples taken from the human body (like blood, urine, or tissue) to provide information about a person's health.
  • Device Description: The Gladiator Hip Stems are physical implants designed to be surgically placed within the body to replace a damaged hip joint.
  • Intended Use: The intended use clearly states that the device is for "uncemented total hip arthroplasty" and is used to "reduce or relieve pain and/or improve hip function." This is a surgical intervention, not a diagnostic test performed on a sample outside the body.

The information provided describes a surgical implant, not a device used for in vitro diagnostic testing.

N/A

Intended Use / Indications for Use

The Gladiator Hip Stems are intended for use in uncemented total hip arthroplasty for reduction or relief of pain and/or improved hip function in skeletally mature patients.
Indications for Use:

    1. non-inflammatory degenerative joint disease such as osteoarthritis, avascular necrosis, ankylosis, protrusio acetabuli, and painful hip dysplasia;
    1. inflammatory degenerative joint disease such as rheumatoid arthritis;
    1. correction of functional deformity; and,
    1. revision procedures where other treatments or devices have failed.

The Gladiator cpTi Plasma Sprayed hip stem is intended for cementless hip arthroplasty. The cemented hip stem is intended for cemented hip arthroplasty.

Product codes (comma separated list FDA assigned to the subject device)

KWA, JDL, LPH, LZO, JDI

Device Description

The Gladiator stems are modular hip stems that couple with modular necks. Design features of the stems are summarized below:

  • Cementless stem with proximal cpTi plasma spray coating.
    • Available in 10 sizes r
    • i Manufactured from Ti alloy
  • . Cemented
    • Available in 5 sizes
    • . Manufactured from CoCr alloy
    • 배 Distal centralizers available

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

Hip

Indicated Patient Age Range

Skeletally mature patients

Intended User / Care Setting

Not Found

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies (study type, sample size, AUC, MRMC, standalone performance, key results)

The Gladiator Hip Stems were evaluated via mechanical testing; including fatigue, fretting; and distraction evaluation. A review of these results indicates that the Gladiator Hip Stems are equivalent to predicate devices and are capable of withstanding expected in vivo loading without failure. The GLADIATOR® Hip Stems have been tested in distal and proximal fatigue evaluation per the loading regimen prescribed by ISO 7206-4, -6 and -8.

Key Metrics (Sensitivity, Specificity, PPV, NPV, etc.)

Not Found

Predicate Device(s): If the device was cleared using the 510(k) pathway, identify the Predicate Device(s) K/DEN number used to claim substantial equivalence and list them here in a comma separated list exactly as they appear in the text. List the primary predicate first in the list.

K100866, K091423, K021346, K012091, K052915, K060358, K953111, K042992, K082924

Reference Device(s): Identify the Reference Device(s) K/DEN number and list them here in a comma separated list exactly as they appear in the text.

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information for the subject device only (e.g. presence / absence, what scope was granted / cleared under the PCCP, any restrictions, etc).

Not Found

§ 888.3330 Hip joint metal/metal semi-constrained, with an uncemented acetabular component, prosthesis.

(a)
Identification. A hip joint metal/metal semi-constrained, with an uncemented acetabular component, prosthesis is a two-part device intended to be implanted to replace a hip joint. The device limits translation and rotation in one or more planes via the geometry of its articulating surfaces. It has no linkage across-the-joint. This generic type of device includes prostheses that consist of a femoral and an acetabular component, both made of alloys, such as cobalt-chromium-molybdenum. The femoral component is intended to be fixed with bone cement. The acetabular component is intended for use without bone cement (§ 888.3027).(b)
Classification. Class III.(c)
Date PMA or notice of completion of PDP is required. A PMA or a notice of completion of a PDP is required to be filed with the Food and Drug Administration on or before May 18, 2016, for any hip joint metal/metal semi-constrained prosthesis with an uncemented acetabular component that was in commercial distribution before May 28, 1976, or that has, on or before May 18, 2016, been found to be substantially equivalent to a hip joint metal/metal semi-constrained prosthesis with an uncemented acetabular component that was in commercial distribution before May 28, 1976. Any other hip joint metal/metal semi-constrained prosthesis with an uncemented acetabular component shall have an approved PMA or a declared completed PDP in effect before being placed in commercial distribution.

0

KIII910 (pq1/2)

OCT 1 4 2011

510{k} Summary of Safety and Effectiveness

In accordance with the Food and Drug Administration Rule to implement provisions of the Safe Medical Devices Act of 1990 and in conformance with 21 CFR 807, this information serves as a Summary of Safety and Effectiveness for the use of the PROFEMUR® Gladiator Hip Stems.

| Submitted By: | Wright Medical Technology, Inc.
5677 Airline Rd, Arlington TN, 38002
(800) 238-7188 |
|--------------------------------------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| Date: | September 30, 2011 |
| Contact Person: | Gregory Neal
Regulatory Affairs Specialist II |
| Proprietary Name: | Gladiator Hip Stems |
| Common Name: | Hip Stem |
| Classification Name and Reference: | 21 CFR 888.3330 Hip joint metal/metal semi-
constrained, with an uncemented acetabular
component prosthesis
Class III |
| Subject Product Code and Panel Code: | Orthopedics/87/KWA, JDL, LPH, LZO, JDI |
| Predicate Devices Name and Number: | PROFEMUR ® Hip System Modular Necks
PROFEMUR ® Z
PROFEMUR ® Hip System
PROFEMUR ® X™ Hip Stem
PROFEMUR ® TL Hip Stem
CORAIL ® Hip Prosthesis
DYNASTY ® BIOFOAM™ Acetabular System
510(k): K100866, K091423, K021346, K012091,
K052915, K060358, K953111, K042992, K082924 |
| Predicate Classification and Number: | Orthopedics/87/ KWA, 888.3330 |

Device Information

A. Device Description

The Gladiator stems are modular hip stems that couple with modular necks. Design features of the stems are summarized below:

  • Cementless stem with proximal cpTi plasma spray coating .
    • Available in 10 sizes r
    • i Manufactured from Ti alloy
  • . Cemented
    • Available in 5 sizes
    • . Manufactured from CoCr alloy
    • 배 Distal centralizers available

1

The Gladiator Hip Stems were evaluated via mechanical testing; including fatigue, fretting; and distraction evaluation. A review of these results indicates that the Gladiator Hip Stems are equivalent to predicate devices and are capable of withstanding expected in vivo loading without failure.

8. Intended Use

The Gladiator Hip Stems are intended for use in uncemented total hip arthroplasty for reduction or relief of pain and/or improved hip function in skeletally mature patients.

Indications for Use

    1. non-inflammatory degenerative joint disease such as osteoarthritis, avascular necrosis, ankylosis, protrusio acetabuli, and painful hip dysplasia;
    1. inflammatory degenerative joint disease such as rheumatoid arthritis;
  • correction of functional deformity; and, 3.
    1. revision procedures where other treatments or devices have failed

The Gladiator cpTi Plasma Sprayed hip stem is intended for cementless hip arthroplasty. The Cemented hip stem is intended for cemented hip arthroplasty.

C. Technological Characteristic of the Device

The GLADIATOR® Hip Stems have the same technological characteristics as the predicate device. GLADIATOR® Hip Stems are straight cemented and uncemented hip stems with a modular design. They feature a proximal trapezoidal cross-section and a distal rectangular cross-section. For fixation stability in three planes, the stem has a vertically tapered profile in the frontal and lateral planes. The materials used for the GLADIATOR® Hip Stems are identical to the materials used for the predicate devices.

D. Nonclinical Testing

The GLADIATOR® Hip Stems have been tested in distal and proximal fatigue evaluation per the loading regimen prescribed by ISO 7206-4, -6 and -8.

E. Clinical Testing

Clinical data was not provided for the class III hip stem.

F. Conclusions

The indications for use of the Gladiator Hip Stems are identical to the previously cleared predicate devices. The design features and materials of the subject devices are substantially equivalent to those of the predicate devices. The fundamental scientific technology of the modified devices has not changed relative to the predicate devices. The safety and effectiveness of the Gladiator Hip Stems are adequately supported by the substantial equivalence information, materials information, and analysis data provided within this Premarket Notification.

2

Food and Drug Administration 10903 New Hampshire Avenue Document Control Room -WO66-G609 Silver Spring, MD 20993-0002

OCT 1 4 2011

Wright Medical Technology, Inc. % Matt Paul 5677 Airline Rd Arlington, TN 38002

Re: K111910

Trade/Device Name: Gladiator Hip Stems Regulation Number: 21 CFR 888.3330 Regulation Name: Hip joint metal/metal semi-constrained, with an uncemented acetabular component prosthesis Regulatory Class: Class III Product Code: KWA, JDL, LPH, LZO, JDI Dated: October 12, 2011 Received: October 13, 2011

Dear Mr. Paul:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you, however, that device labeling must be truthful and not misleading.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must

3

Page - 2 - Mr. Matt Paul

comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); medical device reporting (reporting of medical device-related adverse events) (21 CFR 803); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please go to http://www.fda.gov/AboutFDA/CentersOffices/CDRH/CDRHOffices/ucm115809.htm for the Center for Devices and Radiological Health's (CDRH's) Office of Compliance. Also, please note the regulation entitled. "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to

http://www.fda.gov/MedicalDevices/Safety/ReportaProblem/default.htm for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance.

You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 796-7100 or at its Internet address http://www.fda.gov/MedicalDevices/ResourcesforYou/Industry/default.htm.

Sincerely yours.

Erin Keith

Sr Mark N. Melkerson Director Division of Surgical, Orthopedic and Restorative Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

4

Indications for Use

510(k) Number (if known): K1119106pq 1/1)

Device Name: Gladiator Hip Stems

Indications For Use:

    1. non-inflammatory degenerative joint disease such as osteoarthritis, avascular necrosis, ankylosis, protrusio acetabuli, and painful hip dysplasia; .
  • inflammatory degenerative joint disease such as rheumatoid arthritis; 2.
  • correction of functional deformity; and, ന്
  • revision procedures where other treatments or devices have failed. 4.

The Gladiator cpTi Plasma Sprayed hip stem is intended for cementless hip arthroplasty.

The Gladiator Cemented hip stem is intended for cemented hip arthroplasty.

Prescription Use _ X (Part 21 CFR 801 Subpart D) AND/OR

Over-The-Counter Use _ (21 CFR 807 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Richard Owens to MXM

(Division Sign-Off) Division of Surgical, Orthopedic, and Restorative Devices

K111910
510(k) Number