K Number
K111069
Device Name
OSTEOSYMBIONICS, ST TEMPORALIS IMPLANT
Date Cleared
2011-09-22

(157 days)

Product Code
Regulation Number
878.3550
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
The OsteoSymbionics ST Temporalis Implant is indicated to correct temporal hollowing in patients who have had surgery involving the pterional / lateral approach to the cranium, including pterional / lateral craniotomy or decompressive craniectomy. The OsteoSymbionics ST Temporalis Implant augments the space normally occupied by the temporalis muscle. The implant is used for the reconstruction of temporal contour deformities; the reconstruction of temporal defects, and / or the augmentation / reconstruction of the space normally occupied by the temporalis muscle / temporal area (s).
Device Description
The OsteoSymbionics Temporal Implants are pre-formed implantable prosthetic implants intended to fill soft-tissue defects in a patient's cranial/craniofacial temporal region. The implants are composed of longterm implantable-grade solid silicone elastomer. The implants are available in left and right, and come in two different sizes, small and medium. The devices are provided sterile, and are attached to native tissue with commercially available suture materials.
More Information

Not Found

No
The summary describes a pre-formed silicone implant for soft-tissue defects and does not mention any computational or analytical capabilities that would suggest AI/ML.

No.
The device is described as an implantable prosthetic used for reconstruction and augmentation of the temporal region, not for treating or curing a disease or disorder.

No.
The text describes a surgically implanted prosthetic device used for reconstruction, not for diagnosing a medical condition.

No

The device description explicitly states the device is a "pre-formed implantable prosthetic implant" composed of "longterm implantable-grade solid silicone elastomer," indicating it is a physical hardware device, not software.

No, this device is not an IVD (In Vitro Diagnostic).

Here's why:

  • IVD Definition: In Vitro Diagnostics are medical devices used to perform tests on samples taken from the human body (like blood, urine, tissue) to provide information about a person's health. These tests are performed outside of the body.
  • Device Description: The OsteoSymbionics ST Temporalis Implant is a pre-formed, implantable prosthetic device made of silicone elastomer. It is surgically implanted into the patient's cranial/craniofacial temporal region to correct physical deformities.
  • Intended Use: The intended use is to physically augment and reconstruct temporal contour deformities and defects. This is a surgical intervention, not a diagnostic test performed on a sample.

The information provided clearly describes a surgically implanted device used for physical reconstruction, which falls outside the scope of In Vitro Diagnostics.

N/A

Intended Use / Indications for Use

The OsteoSymbionics ST Temporalis Implant is Indicated to correct temporal hollowing in patients who have had surgery involving the pterional / Lateral approach to the cranium, including pterional / lateral craniotomy or decompressive craniotomy. The OsteoSymbionics St Temporalis Implant augments the space normally occupied by the temporalis muscle. The Implant is used for the reconstruction of temporal contour deformities; the reconstruction of temporal defects, and / or the augmentation / reconstruction of the space normally occupied by the temporalis muscle / temporal area (s).

Product codes

MNF

Device Description

The OsteoSymbionics Temporal Implants are pre-formed implantable prosthetic implants intended to fill soft-tissue defects in a patient's cranial/craniofacial temporal region. The implants are composed of longterm implantable-grade solid silicone elastomer. The implants are available in left and right, and come in two different sizes, small and medium. The devices are provided sterile, and are attached to native tissue with commercially available suture materials.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

cranial/craniofacial temporal region / temporalis muscle / temporal area(s)

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Not Found

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies (study type, sample size, AUC, MRMC, standalone performance, key results)

The non-clinical safety and effectiveness data established that the OsteoSymbionics Temporal Implant has comparable chemical characteristics as the Implatech device (based upon literature comparison). Physical property testing included tensile, durometer and tear strength of materials representing the manufacturing and sterilization parameters. Biocompatibility data from the MAF was augmented with an agar overlay cytotoxicity study. Bioburden testing was conducted to support the sterilization testing. LAL testing demonstrated less than 0.005EU/ml. Shelf-life aging labeling claims are supported by product use history.

Key Metrics (Sensitivity, Specificity, PPV, NPV, etc.)

Not Found

Predicate Device(s)

K943644, K002568

Reference Device(s)

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information

Not Found

§ 878.3550 Chin prosthesis.

(a)
Identification. A chin prosthesis is a silicone rubber solid device intended to be implanted to augment or reconstruct the chin.(b)
Classification. Class II.

0

K111069

SECTION 5 510(K) SUMMARY

Submitted on behalf of:

SEP 2 2 2011

Company Name: Ms. Cynthia Brogan, President OsteoSymbionics, LLC 1768 East 25th Street Cleveland, Ohio 44114 Registration No: 3007223102 Phone: (216) 881-8500 e-mail: cb@osteosymbionics.com

Submitted by:

Elaine Duncan, M.S.M.E., RAC

President, Paladin Medical, Inc. PO Box 560 Stillwater, MN 55082 Telephone: Fax:

715-549-6035 715-549-5380

CONTACT PERSON: DATE PREPARED:

Elaine Duncan September 12, 2011

Trade or Proprietary Name: Common Name: Classification Name: Classification

OsteoSymbionics Temporal Implant Temporal Implant Implant, Temporal (ProCode): MNF

SUBSTANTIALLY EQUIVALENT TO:

The OsteoSymbionics Temporal Implants (made from silicone elastomer technology) are substantially equivalent to the following legally marketed predicate devices: Inc., Implantech Temporal Implant - K943644 (made from silicone elastomer) and Porex Surgical, Inc., Medpor Pterional Surgical Implant - K002568, made from porous polyethylene.

DESCRIPTION of the DEVICE:

The OsteoSymbionics Temporal Implants are pre-formed implantable prosthetic implants intended to fill soft-tissue defects in a patient's cranial/craniofacial temporal region. The implants are composed of longterm implantable-grade solid silicone elastomer. The implants are available in left and right, and come in two different sizes, small and medium. The devices are provided sterile, and are attached to native tissue with commercially available suture materials.

INDICATIONS FOR USE:

The OsteoSymbionics ST Temporalis Implant is Indicated to correct temporal hollowing in patients who have had surgery involving the pterional / Lateral approach to the cranium, including pterional / lateral craniotomy or decompressive craniotomy. The OsteoSymbionics St Temporalis Implant augments the space normally occupied by the temporalis muscle. The Implant is used for the reconstruction of temporal contour deformities; the reconstruction of temporal defects, and / or the augmentation / reconstruction of the space normally occupied by the temporalis muscle / temporal area (s).

SUMMARY of TESTING:

The non-clinical safety and effectiveness data established that the OsteoSymbionics Temporal Implant has comparable chemical characteristics as the Implatech device (based upon literature comparison). Physical property testing included tensile, durometer and tear strength of materials representing the manufacturing and sterilization parameters. Biocompatibility data from the MAF was augmented with an agar overlay cytotoxicity study. Bioburden testing was conducted to support the sterilization testing. LAL testing demonstrated less than 0.005EU/ml. Shelf-life aging labeling claims are supported by product use history.

1

Image /page/1/Picture/1 description: The image shows the logo for the U.S. Department of Health and Human Services. The logo is a circular emblem with the department's name encircling a stylized image of an eagle. The eagle is depicted with three curved lines representing its body and wings, and a single line for its tail. The text is arranged around the circle, with "U.S. DEPARTMENT OF HEALTH & HUMAN SERVICES" at the top and "USA" at the bottom.

Public Flealth Service

Food and Drug Administration 10903 New Hampshire Avenue Document Control Room -WQ66-G605 Silver Spring, MD 20993-0002

OsteoSymbionics. LLC % Paladin Medical, Inc. Elaine Duncan. MS, ME. RAC P.O. Box 560 Stillwater, Minnesota 55082

SEP 2 2 2011

Re: K111069

Trade/Device Name: OsteoSymbionics ST Temporalis Implant Regulation Number: 21 CFR 878.3550 Regulation Name: Chin prosthesis Regulatory Class: II Product Code: MNF Dated: September 12, 2011 Received: September 14, 2011

Dear Ms. Duncan:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food. Drug. and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA), You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you, however, that device labeling must be truthful and not misleading.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21

2

Page 2 - Elaine Duncan, MS, ME, RAC

CFR Part 807); labeling (21 CFR Part 801); medical device reporting (reporting of medical device-related adverse events) (21 CFR 803); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please go to http://www.lda.gov/AboutFDA/CemersOfTices/CDRHOffices/ucm115809.html for the Center for Devices and Radiological Health's (CDRH's) Office of Compliance. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to

http://www.fda.gov/MedicalDevices/Safety/ReportalProblem/default.htm for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance

You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its tollofreen mber (800) 638-2041 or (301) 796-7100 or at its Internet address http://www.fda.gov/MedicalDevices/Resourcesfor You/Industrv/default.htm.

Sincerely yours.

Erint Keith

Mark N. Melkerson Director Division of Surgical, Orthopedic and Restorative Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

3

Kiii069

Indications for Use

510(k) Number (if known):

Device Name:

The OsteoSymbionics ST Temporalis Implant is indicated to correct temporal hollowing in patients who have had surgery involving the pterional / lateral approach to the cranium, including pterional / lateral craniotomy or decompressive craniectomy. The OsteoSymbionics ST Temporalis Implant augments the space normally occupied by the temporalis muscle. The implant is used for the reconstruction of temporal contour deformities; the reconstruction of temporal defects, and / or the augmentation / reconstruction of the space normally occupied by the temporalis muscle / temporal area (s).

Prescription Use x (Part 21 CFR 801 Subpart D)

AND/OR

Over-The-Counter Use (21 CFR 801 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE OF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Division Sign-Off

Daniel Krane for MXM
(Division Sign Off)

(Division Sim Division of Surgical, Orthopedic. and Restorative Devices

510(k) Number K111069

Page 1 of 1