K Number
K100614
Device Name
HALLMARK ANTERIOR CERVCIAL PLATE SYSTEM, HALLMARK FIVE-LEVEL CERVICAL PLATES
Date Cleared
2010-05-04

(61 days)

Product Code
Regulation Number
888.3060
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
The Hallmark™ Anterior Cervical Plate System is intended for anterior fixation to the cervical spine from C2 to C7. The specific clinical indications include: a) Degenerative disc disease (as defined as back pain of discogenic origin with degenerative disc confirmed by patient history and radiographic studies); b) Spondylolisthesis: c) Fracture; d) Spinal stenosis; e) Deformities (i.e., scoliosis, kyphosis, and/or lordosis) f) Tumor; g) Pseudoarthrosis; h) Revision of previous surgery
Device Description
The Hallmark Anterior Cervical Plate System is comprised of a variety of non-sterile, single use, titanium alloy (6AL-4V ELI, per ASTM F136) components that allow a surgeon to build an anterior cervical implant construct. The system is attached to the anterior aspect of the vertebral body by means of screws to the cervical spine. The system consists of an assortment of screws, plates and associated instrumentation.
More Information

Not Found

No
The device description and performance studies focus on mechanical properties and equivalence to predicate devices, with no mention of AI or ML.

Yes
The device is intended for anterior fixation to the cervical spine to treat various medical conditions like degenerative disc disease, fractures, tumors, and deformities, which are therapeutic interventions.

No

Explanation: The device is an anterior cervical plate system used for fixation to the cervical spine, designed to build an implant construct. Its intended use and indications for use describe surgical treatment for spinal conditions, not diagnosis.

No

The device description explicitly states it is comprised of physical components made of titanium alloy, including screws, plates, and associated instrumentation, which are hardware.

Based on the provided information, this device is not an IVD (In Vitro Diagnostic).

Here's why:

  • IVD Definition: In Vitro Diagnostics are tests performed on samples taken from the human body, such as blood, urine, or tissue, to detect diseases, conditions, or infections.
  • Device Description: The Hallmark Anterior Cervical Plate System is described as a system of titanium alloy components (screws, plates, and instrumentation) intended for surgical implantation to fix the cervical spine.
  • Intended Use: The intended use is for anterior fixation to the cervical spine for various conditions. This is a surgical procedure, not a diagnostic test performed on a sample outside the body.

The device is a surgical implant used in vivo (within the living body), not an in vitro diagnostic test.

N/A

Intended Use / Indications for Use

The Hallmark™ Anterior Cervical Plate System is intended for anterior fixation to the cervical spine from C2 to C7. The specific clinical indications include:

  • a) Degenerative disc disease (as defined as back pain of discogenic origin with
  • degenerative disc confirmed by patient history and radiographic studies);
  • b) Spondylolisthesis:
  • c) Fracture;
  • d) Spinal stenosis;
  • e) Deformities (i.e., scoliosis, kyphosis, and/or lordosis)
  • f) Tumor;
  • g) Pseudoarthrosis;
  • h) Revision of previous surgery

Product codes (comma separated list FDA assigned to the subject device)

KWQ

Device Description

The Hallmark Anterior Cervical Plate System is comprised of a variety of non-sterile, single use, titanium alloy (6AL-4V ELI, per ASTM F136) components that allow a surgeon to build an anterior cervical implant construct. The system is attached to the anterior aspect of the vertebral body by means of screws to the cervical spine. The system consists of an assortment of screws, plates and associated instrumentation.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

cervical spine from C2 to C7

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Not Found

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies (study type, sample size, AUC, MRMC, standalone performance, key results)

Mechanical evaluations were conducted to demonstrate that the Hallmark Anterior Cervical Plate System with the addition of the Five-Level Cervical Plates is substantially equivalent to predicate devices and systems that have been cleared by FDA for the purpose of building a spinal implant construct in the cervical spine.

Key Metrics (Sensitivity, Specificity, PPV, NPV, etc.)

Not Found

Predicate Device(s): If the device was cleared using the 510(k) pathway, identify the Predicate Device(s) K/DEN number used to claim substantial equivalence and list them here in a comma separated list exactly as they appear in the text. List the primary predicate first in the list.

K050892, K073479

Reference Device(s): Identify the Reference Device(s) K/DEN number and list them here in a comma separated list exactly as they appear in the text.

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information for the subject device only (e.g. presence / absence, what scope was granted / cleared under the PCCP, any restrictions, etc).

Not Found

§ 888.3060 Spinal intervertebral body fixation orthosis.

(a)
Identification. A spinal intervertebral body fixation orthosis is a device intended to be implanted made of titanium. It consists of various vertebral plates that are punched into each of a series of vertebral bodies. An eye-type screw is inserted in a hole in the center of each of the plates. A braided cable is threaded through each eye-type screw. The cable is tightened with a tension device and it is fastened or crimped at each eye-type screw. The device is used to apply force to a series of vertebrae to correct “sway back,” scoliosis (lateral curvature of the spine), or other conditions.(b)
Classification. Class II.

0

Premarket Notification Special 510(k) Blackstone Medical, Inc. Hallmark Anterior Cervical Plate System Modification

510(k) SUMMARY

Hallmark Anterior Cervical Plate System Modification - Five-Level Cervical Plates

Darla Chew, Regulatory Affairs Director

Sponsor:

..............................................................................................................................................................................

Blackstone Medical, Inc. 1211 Hamburg Turnpike Suite 300 Wayne, NJ 07470

DarlaChew@Orthofix.com

Regulatory Affairs Manger

1720 Bray Central Dr. McKinney, TX 75069

3004606875

469-742-8824 469-742-2256

Martin Sprunck

Orthofix, Inc.

2183449

MAY - 4 2010

Registration Number:

Contact Person: Telephone Number: Fax Number: Email:

Submitter:

Manufacturer:

Registration Number:

Contract Manufacturer:

Structure Medical, Inc. 2975 S. Horseshoe Drive Naples, Florida 34104

System Name:

Trade Name (Component): Hallmark Five-Level Cervical Plates

Anterior Cervical Plate System Common Name (System):

Product Code: KWQ - Appliance, Fixation, Spinal Intervertebral Body

Class II Device, 888.3060 - Spinal intervertebral body Regulatory Classification: fixation orthosis

Hallmark Anterior Cervical Plate System

Orthopedic Device Panel Review Panel:

Predicate Devices:

Blackstone Hallmark Anterior Cervical Plate System (K050892 SE 5/11/05) Life Spine Kinetic-SL Anterior Cervical Plate System (K073479 SE 1/9/28)

Hallmark Anterior Cervical Plate System Modification - 510(k) Summary

1

Intended Use / Indications for Use

The Hallmark™ Anterior Cervical Plate System is intended for anterior fixation to the cervical spine from C2 to C7. The specific clinical indications include:

  • a) Degenerative disc disease (as defined as back pain of discogenic origin with
  • degenerative disc confirmed by patient history and radiographic studies);
  • b) Spondylolisthesis:
  • c) Fracture;
  • d) Spinal stenosis;
  • e) Deformities (i.e., scoliosis, kyphosis, and/or lordosis)
  • f) Tumor;
  • g) Pseudoarthrosis;
  • h) Revision of previous surgery

Technological Characteristics

The Hallmark Anterior Cervical Plate System is comprised of a variety of non-sterile, single use, titanium alloy (6AL-4V ELI, per ASTM F136) components that allow a surgeon to build an anterior cervical implant construct. The system is attached to the anterior aspect of the vertebral body by means of screws to the cervical spine. The system consists of an assortment of screws, plates and associated instrumentation.

Basis of Substantial Equivalence

Mechanical evaluations were conducted to demonstrate that the Hallmark Anterior Cervical Plate System with the addition of the Five-Level Cervical Plates is substantially equivalent to predicate devices and systems that have been cleared by FDA for the purpose of building a spinal implant construct in the cervical spine.

Hallmark Anterior Cervical Plate System Modification - 510(k) Summary

2

Image /page/2/Picture/1 description: The image shows the logo for the U.S. Department of Health and Human Services. The logo features a stylized depiction of an eagle or bird with outstretched wings. The bird is positioned within a circular border, and the text "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" is arranged around the upper portion of the circle.

Food and Drug Administration 10903 New Hampshire Avenue Document Control Room -WO66-G609 Silver Spring, MD 20993-0002

MAY - 4 2010

Blackstone Medical, Inc. % Ms. Darla Chew Regulatory Affairs Director 1211 Hamburg Turnpike, Suite 300 Wayne, New Jersey 07470

Re: K100614

Trade/Device Name: Hallmark Five-Level Cervical Plates Regulation Number: 21 CFR 888.3060 Regulation Name: Spinal intervertebral body fixation orthosis Regulatory Class: Class II Product Code: KWQ Dated: April 27, 2010 Received: April 28, 2010

Dear Ms. Chew:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you; however, that device labeling must be truthful and not misleading.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act

3

Page 2 - Ms. Darla Chew

or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); medical device reporting (reporting of medical device-related adverse events) (21 CFR 803); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please go to http://www.fda.gov/AboutFDA/CentersOffices/CDRH/CDRHOffices/ucm115809.htm for the Center for Devices and Radiological Health's (CDRH's) Office of Compliance. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to

http://www.fda.gov/MedicalDevices/Safety/ReportaProblem/default.htm for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance.

You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 796-7100 or at its Internet address http://www.fda.gov/MedicalDevices/ResourcesforYou/Industry/default.htm.

Sincerely vours. Mark Melke

Director Division of Surgical, Orthopedic, and Restorative Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

4

Indications for Use Statement

510(k) Number (if known):

System Name: Hallmark Anterior Cervical Plate System Device Name: Hallmark Five-Level Cervical Plates

Indications for Use:

The Hallmark 151 Anterior Cervical Plate System is intended for anterior fixation to the cervical spine from C2 to C7. The specific clinical indications include:

  • a) Degenerative disc disease (as defined as back pain of discogenic origin with degenerative disc confirmed by patient history and radiographic studies);
  • b) Spondylolisthesis;
  • c) Fracture;

d) Spinal stenosis;

  • e) Deformities (i.e., scoliosis, kyphosis, and/or lordosis)
    f) Tumor;

g) Pseudoarthrosis;

  • h) Revision of previous surgery
    Prescription Use X (Part 21 C.F.R. 801 Subpart D) AND/OR

Over-The-Counter Use (21 C.F.R. 807 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE -- CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

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(Division Sign-Off) Division of Surgical, Orthopedic, and Restorative Devices

K 100614 510(k) Number_