K Number
K100029
Device Name
MEPILEX BORDER AG DRESSING
Date Cleared
2010-09-15

(252 days)

Product Code
Regulation Number
N/A
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
Mepilex Border Ag dressing is indicated for the management of exuding wounds such as leg and foot ulcers, pressure ulcers, traumatic and surgical wounds, superficial and partial thickness burns. Mepilex Border Ag can also be used under compression bandaging. Silver sulfate present in the dressing helps reduce microbial colonization on the dressing.
Device Description
Mepilex Border Ag consists of a Safetac soft silicone wound contact layer, an absorbent polyurethane foam pad containing a silver compound and activated carbon, a layer with super absorbent polyacrylate fibres, a non woven and a vapour permeable waterproof film. Mepilex Border Ag is a soft silicone foam dressing that absorbs exudate, maintains a moist wound healing environment and has antimicrobial properties. Mepilex Border Ag contains silver sulfate that when in contact with fluid releases silver ions to inactivate a wide range of wound related pathogens (bacteria and fungi), shown in vitro. By reducing the number of wound related putnogens (bacteria and lung), shown in the Mepilex Border Ag has been shown to inactivate wound related pathogens up to 7 days in vitro.
More Information

Mepilex Ag Foam Dressing

Not Found

No
The device description and performance studies focus on the physical and antimicrobial properties of the wound dressing, with no mention of AI or ML technology.

No
The device is a wound dressing designed for managing exuding wounds and preventing microbial colonization, not for providing a therapeutic intervention like drug delivery or structural support.

No

The device description clearly states it is a wound dressing that absorbs exudate, maintains a moist wound healing environment, and has antimicrobial properties. There is no mention of it being used to diagnose conditions or diseases.

No

The device description clearly indicates it is a physical wound dressing composed of multiple material layers, not software.

Based on the provided information, this device is not an IVD (In Vitro Diagnostic).

Here's why:

  • Intended Use: The intended use is for the management of exuding wounds. This is a therapeutic application, not a diagnostic one.
  • Device Description: The description details a wound dressing with absorbent and antimicrobial properties. It does not describe a device used to examine specimens from the human body to provide information for diagnosis, monitoring, or screening.
  • Performance Studies: The performance studies focus on biocompatibility and antimicrobial properties of the dressing itself, not on the analysis of biological samples.
  • Lack of IVD Characteristics: There is no mention of analyzing blood, urine, tissue, or any other biological specimen. There is no mention of providing diagnostic information.

The mention of "shown in vitro" refers to laboratory testing of the dressing's antimicrobial properties against pathogens in a controlled environment, not the use of the device to diagnose a condition in a patient.

N/A

Intended Use / Indications for Use

Mepilex Border Ag dressing is indicated for the management of exuding wounds such as leg and foot ulcers, pressure ulcers, traumatic and surgical wounds, superficial and partial thickness burns. Mepilex Border Ag can also be used under compression bandaging. Silver sulfate present in the dressing helps reduce microbial colonization on the dressing.

Product codes (comma separated list FDA assigned to the subject device)

FRO

Device Description

Mepilex Border Ag consists of a Safetac soft silicone wound contact layer, an absorbent polyurethane foam pad containing a silver compound and activated carbon, a layer with super absorbent polyacrylate fibres, a non woven and a vapour permeable waterproof film.

Mepilex Border Ag is a soft silicone foam dressing that absorbs exudate, maintains a moist wound healing environment and has antimicrobial properties.

Mepilex Border Ag contains silver sulfate that when in contact with fluid releases silver ions to inactivate a wide range of wound related pathogens (bacteria and fungi), shown in vitro. By reducing the number of wound related putnogens (bacteria and lung), shown in the

Mepilex Border Ag has been shown to inactivate wound related pathogens up to 7 days in vitro.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

Not Found

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Not Found

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies (study type, sample size, AUC, MRMC, standalone performance, key results)

Summary of Biocompatibility Testing:
Mepilex Border Ag was tested for cytotoxicity, sensitization and irritation and was found to be non-cytotoxic, non-irritating and non-sensitizing.

Summary of Testing for Anti-microbial Properties
Mepilex Border Ag has been shown to provide a barrier against microbial contamination and inactivates a broad range of bacteria and function and function of the blank on and final and ASTM E2149-01: "Determining antimicrobial activity of invol penod as delivolistian in
Mepilex Border Ag has also been shown to inactivate representative bacteria and fungi for up to 8 days, as demonstrated by ASTM E2149-01.

Mepilex Border Ag also shows a sustained release of silver over this time period. Mepilex Ag has also been shown to inactivate bacteria within 30 hours, as in demonstrated by ASTM E2149-01 "Determining antimicrobial activity of immobilized antimicrobial agents".

Key Metrics (Sensitivity, Specificity, PPV, NPV, etc.)

Not Found

Predicate Device(s): If the device was cleared using the 510(k) pathway, identify the Predicate Device(s) K/DEN number used to claim substantial equivalence and list them here in a comma separated list exactly as they appear in the text. List the primary predicate first in the list.

Mepilex Ag Foam Dressing

Reference Device(s): Identify the Reference Device(s) K/DEN number and list them here in a comma separated list exactly as they appear in the text.

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information for the subject device only (e.g. presence / absence, what scope was granted / cleared under the PCCP, any restrictions, etc).

Not Found

N/A

0

Section 12: 510(k) Summary

510(k) SUMMARY

Applicant:

Mölnlycke Health Care 5550 Peachtree Parkway Suite 500 Norcross, GA 30092

Contact Person:

Steven Dowdley Director of Regulatory Affairs 678-250-7930 Tel.: Fax: 678-250-7986

Proprietary Name:

Device Name:

Mepilex Border Ag Dressing Common/Usual Name: Silver Dressing Device Classification: Unclassified

Predicate Device Mepilex Ag Foam Dressing

Description:

Mepilex Border Ag consists of a Safetac soft silicone wound contact layer, an absorbent polyurethane foam pad containing a silver compound and activated carbon, a layer with super absorbent polyacrylate fibres, a non woven and activeled canvaled candon, a fayer w
absorbent polyacrylate fibres, a non woven and a vapour permeable waterproof film.

Mepilex Border Ag is a soft silicone foam dressing that absorbs exudate, maintains a moist wound healing environment and has antimicrobial properties.

Mepilex Border Ag contains silver sulfate that when in contact with fluid releases silver ions to inactivate a wide range of wound related pathogens (bacteria and fungi), shown in vitro. By reducing the number of wound related putnogens (bacteria and lung), shown in the

Mepilex Border Ag has been shown to inactivate wound related pathogens up to 7 days in vitro.

Intended Use:

Mepilex Border Ag dressing is indicated for the management of exuding wounds such as leg and foot ulcers, pressure ulcers, to the management of extunity wounds, such as legal burns. Mepilex Border Ag can also be used under compression bandaging. Silver sulfate present in the dressing helps reduce microbial colonization on the dressing.

Summary of Biocompatibility Testing:

Mepilex Border Ag was tested for cytotoxicity, sensitization and irritation and was found to be non-cytotoxic, non-irritating and non-sensitizing.

Summary of Testing for Anti-microbial Properties

Mepilex Border Ag has been shown to provide a barrier against microbial contamination and inactivates a broad range of bacteria and function and function of the blank on and final and ASTM E2149-01: "Determining antimicrobial activity of invol penod as delivolistian in

Premarket Notification: Mepilex®Ag

Mölnlycke Health Care 2

1

K100029
page 2 of 2

Mepilex Border Ag has also been shown to inactivate representative bacteria and fungi for up to 8 days, as demonstrated by ASTM E2149-01.

Mepilex Border Ag also shows a sustained release of silver over this time period. Mepilex Ag has also been shown to inactivate bacteria within 30 hours, as in demonstrated by ASTM E2149-01 "Determining antimicrobial activity of immobilized antimicrobial agents".

Conclusion:

The date provided in this 510(k) summary concludes that Mepilex Border Ag is substantially equivalent to the currently marketed Mary of need inder in the producting to oubstantial

2

DEPARTMENT OF HEALTH & HUMAN SERVICES

Image /page/2/Picture/1 description: The image shows the logo for the U.S. Department of Health & Human Services. The logo consists of a circular seal with the text "DEPARTMENT OF HEALTH & HUMAN SERVICES • USA" arranged around the perimeter. Inside the circle is a stylized design featuring three abstract shapes that resemble waves or flowing lines.

Food and Drug Administration 10903 New Hampshire Avenue Document Control Room -WO66-G609 Silver Spring, MD 20993-0002

Mölnlycke Health Care % Mr. Steven Dowdley Global Director of Regulatory Affairs 5550 Peachtree Parkway60 Middleton Avenue North Haven, Connecticut 06473

SEP 1 5 2010

Re: K100029

Trade/Device Name: Mepilex® Border Ag Regulatory Class: Unclassified Product Code: FRO Dated: August 18, 2010 Received: August 25, 2010

Dear Mr. Dowdley:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food. Drug. and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you, however, that device labeling must be truthful and not misleading.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations. Title 21. Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); medical device reporting (reporting of medical device-related adverse events) (21 CFR 803); good manufacturing practice requirements as set

3

Page 2 - Mr. Steven Dowdley

forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please go to http://www.fda.gov/AboutFDA/CentersOffices/CDRH/CDRHOffices/ucm115809.html for the Center for Devices and Radiological Health's (CDRH's) Office of Compliance. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to

http://www.fda.gov/MedicalDevices/Safety/ReportaProblem/default.htm for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance.

You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 796-7100 or at its Internet address http://www.fda.gov/MedicalDevices/Resourcesfor You/Industry/default.htm.

Sincerely yours.

erely yours,

N. Melkerson

Mark N. Melkerso Director Division of Surgical, Orthopedic and Restorative Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

4

Section 3: Indications for Use Statement

PREMARKET NOTIFICATION

Indications for Use

510(k) Number K1000029: Device Name: Mepilex® Border Ag

Indications for Use:

Mepilex Border Ag dressing is indicated for the management of exuding wounds such as leg and foot ulcers, pressure ulcers, traumatic and surgical wounds, superficial and partial thickness burns. Mepilex Border Ag can also be used under compression bandaging. Silver sulfate present in the dressing helps reduce microbial colonization on the dressing.

Prescription Use
(Part 21 CFR 801 Subpart D)

Over-The-Counter Use AND/OR

(21 CFR 801 Subpart C)

. (PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER-PAGE OF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

David KroskeillKM

(Division Sign-C Division of Surgical, Orthopedic, and Restorative Devices

510(k) Number K100029

Premarket Notification: Mepilex®Ag

Mölnlycke Health Care