K Number
K093714
Manufacturer
Date Cleared
2009-12-10

(8 days)

Product Code
Regulation Number
892.1570
Reference & Predicate Devices
Predicate For
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

The SQNOACE X8 system and transducers are intended for diagnostic ultrasound imaging and fluid analysis of the human body. The clinical applications include: General, abdomen, obstetrics, gynecology, vascular, extremity, pediatric, cardiac, breast, urology, neonatal cephalic, trans-esophageal. and etc.

Device Description

The SONOACE X8 is a general purpose, mobile, software controlled, diagnostic ultrasound system. Its function is to acquire ultrasound data and to display the data as 2D mode, M mode, Color Doppler mode, Power Doppler mode, PW Spectral Doppler, CW Spectral Doppler mode, and Tissue Doppler Image mode on the LCD display. It also provides the 3D/4D imaging mode using the 3D/4D probe in the Mechanical scan mode. The SONOACE X8 has real time acoustic output display with two basic indices, a mechanical index and a thermal index, which are both automatically displayed. The system also provides for the measurement of anatomical structures and for analysis packages that provide information used for clinical diagnostic purposes by competent health care professionals.

AI/ML Overview

The provided submission (K093714) for the SONOACE X8 Diagnostic Ultrasound System is a 510(k) Premarket Notification. This type of submission focuses on demonstrating "substantial equivalence" to a legally marketed predicate device, rather than proving safety and effectiveness through clinical trials with specific acceptance criteria and performance metrics against ground truth.

Therefore, the document does not contain the information requested in questions 1-9 directly. The submission establishes equivalence based on technological characteristics and intended uses being similar to previously cleared devices (K0635580 and K092159). There are no specific acceptance criteria for performance metrics (like sensitivity, specificity, or similar quantitative measures for an AI-enabled device) or a study proving the device meets such criteria as would be found in a de novo or PMA submission.

The document discusses compliance with recognized safety and performance standards for diagnostic ultrasound systems as part of establishing substantial equivalence. These standards are general for the device type, not specific acceptance criteria for a novel AI capability's performance.

Here's what can be inferred or stated from the document, with explanations why other information is not present:


1. A table of acceptance criteria and the reported device performance

  • Acceptance Criteria: Not explicitly stated as performance metrics (e.g., sensitivity, specificity, accuracy) for a specific clinical task. The "acceptance criteria" for a 510(k) submission like this are implicitly demonstrating substantial equivalence to predicate devices and adherence to relevant industry standards for safety and fundamental operational characteristics. The device is assessed against safety standards such as UL 60601-1, CSA C22.2 No. 601.1, IEC60601-2-37, EN/IEC60601-1, EN/IEC60601-1-2, NEMA UD-2, NEMA UD-3, IEC 61157, and ISO10993-1 (biocompatibility).
  • Reported Device Performance: No specific quantitative performance metrics (like sensitivity, specificity, etc.) are reported in the summary that would be tied to clinical acceptance criteria. The performance is deemed substantially equivalent to the predicate devices for the listed clinical applications (General, abdomen, obstetrics, gynecology, vascular, extremity, pediatric, cardiac, breast, urology, neonatal cephalic, trans-esophageal, etc.) and modes of operation (2D, M-mode, Color Doppler, Power Doppler, PW Spectral Doppler, CW Spectral Doppler, Tissue Doppler Image, 3D/4D).

2. Sample size used for the test set and the data provenance (e.g., country of origin of the data, retrospective or prospective)

This information is not provided in the 510(k) summary. For ultrasound systems seeking substantial equivalence, performance is typically confirmed through engineering testing, comparison to predicate devices, and adherence to performance standards, rather than extensive clinical efficacy studies with specific test sets in the same manner as a novel AI algorithm.


3. Number of experts used to establish the ground truth for the test set and the qualifications of those experts (e.g., radiologist with 10 years of experience)

This information is not provided. Ground truth establishment by experts for specific clinical tasks is generally not required for this type of 510(k) submission, as it's not evaluating the diagnostic performance of a novel AI algorithm against a reference standard.


4. Adjudication method (e.g., 2+1, 3+1, none) for the test set

This information is not provided. Clinical study design details such as adjudication methods are not typically part of a 510(k) summary for a general diagnostic ultrasound system.


5. If a multi-reader multi-case (MRMC) comparative effectiveness study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

This information is not applicable/provided. The SONOACE X8 is a diagnostic ultrasound system, not explicitly described as having AI assistance for human readers in this submission. Therefore, an MRMC comparative effectiveness study regarding AI assistance would not be relevant to this submission.


6. If a standalone (i.e., algorithm only without human-in-the-loop performance) was done

This information is not applicable/provided. The SONOACE X8 is a hardware and software system for generating ultrasound images and data, not a standalone algorithm.


7. The type of ground truth used (expert consensus, pathology, outcomes data, etc.)

This information is not provided. As explained above, specific ground truth for performance evaluation of a novel diagnostic claim is not presented in this substantial equivalence summary. The "ground truth" for a general ultrasound system is its ability to accurately produce images and measurements in accordance with its intended use and technical specifications, which would be verified through engineering and phantom testing, and comparison to predicate devices.


8. The sample size for the training set

This information is not applicable/provided. This submission does not pertain to an AI algorithm that would have a training set.


9. How the ground truth for the training set was established

This information is not applicable/provided. This submission does not pertain to an AI algorithm that would have a training set with established ground truth.


In summary: The K093714 document is a 510(k) summary for a diagnostic ultrasound system. Its purpose is to demonstrate substantial equivalence to existing devices and compliance with safety and performance standards for ultrasound technology. It does not provide the kind of performance data (e.g., accuracy, sensitivity, specificity) and study details (sample sizes, ground truth establishment, expert qualifications, adjudication methods) that would be expected for a novel AI-enabled device with specific diagnostic claims requiring clinical validation.

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K093714

510(k) Premarket Notification

SONOACE X8 Diagnostic Ultrasound System

DEC 1 0 2009

510(K) SUMMARY OF SAFETY AND EFFECTIVENESS

This summary of safety and effectiveness is provided as part of this Premarket Notification in compliance with 21 CFR, Part 807, Subpart E, Section 807.92.

1. Submitter's Information: 21 CFR 807.92(a)(1)

MEDISON CO., LTD. 1003, Daechi-dong, Gangnam-gu, Seoul 135-280, Korea

Contact Person:

Mr. Kyung-Am, Shim Regulatory Affairs Manager

Telephone:82.2.2194.1381
Facsimile:82.2.2194.1399
Email:kashim@medison.com

Data Prepared: September 7, 2009

2. Name of the device:

Common/Usual Name:

Diagnostic Ultrasound System and Accessories

Proprietary Name:

SONOACE X8 Diagnostic Ultrasound System

Classification Names:FR NumberProduct Code
Ultrasonic Pulsed Doppler Imaging System892.1550IYN
Ultrasound Pulsed Echo Imaging System892.1560IYO
Diagnostic Ultrasound Transducer892.1570ITX

3. Identification of the predicate or legally marketed device:

K063580, SONOACE X8 Diagnostic Ultrasound System K092159, ACCUVIX V20 Diagnostic Ultrasound System

4. Device Description:

The SONOACE X8 is a general purpose, mobile, software controlled, diagnostic ultrasound system. Its function is to acquire ultrasound data and to display the data as 2D mode, M mode, Color Doppler mode, Power Doppler mode, PW Spectral Doppler, CW Spectral Doppler mode, and Tissue Doppler Image mode on the LCD display. It also provides the 3D/4D imaging mode using the 3D/4D probe in the Mechanical scan mode.

The SONOACE X8 has real time acoustic output display with two basic indices, a

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mechanical index and a thermal index, which are both automatically displayed. The system also provides for the measurement of anatomical structures and for analysis packages that provide information used for clinical diagnostic purposes by competent health care professionals.

The SONOACE X8 has been designed to meet the following product safety standards:

  • UL 60601-1, Safety requirements for Medical Equipment
  • CSA C22.2 No. 601.1, Safety requirements for Medical Equipment
  • IEC60601-2-37. Diagnostic Ultrasound Safety Standards
  • EN/IEC60601-1, Safety requirements for Medical Equipment
  • EN/IEC60601-1-2, EMC requirements for Medical Equipment
  • NEMA UD-2. Acoustic Output Measurement Standard for Diagnostic Ultrasound Equipment
  • NEMA UD-3, Standard for Real Time Display of Thermal and Mechanical Acoustic Output Indices on Diagnostic Ultrasound Equipment
  • IEC 61157. Declaration of the acoustic output
  • ISO10993-1. Biocompatibility

5. Intended Uses:

The SQNOACE X8 system and transducers are intended for diagnostic ultrasound imaging and fluid analysis of the human body.

The clinical applications include:

General, abdomen, obstetrics, gynecology, vascular, extremity, pediatric, cardiac, breast, urology, neonatal cephalic, trans-esophageal. and etc.

6. Technological Characteristics:

The SONOACE X8 is substantially equivalent to the SONOACE X8 Diagnostic Ultrasound System, cleared via K063580, and the ACCUVIX V20 Diagnostic Ultrasound System, cleared via K092159. All systems transmit ultrasonic energy into patients, then perform post processing of received echoes to generate on-screen display of anatomic structures and fluid flow within the body. All system allow for specialized measurements of structures and flow, and calculations.

END of 510(K) Summary

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Image /page/2/Picture/0 description: The image shows the logo for the U.S. Department of Health & Human Services. The logo consists of a stylized human figure with three arms or extensions, representing health and human services. The figure is positioned to the right of a circular text that reads "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA".

DEPARTMENT OF HEALTH & HUMAN SERVICES

Food and Drug Administration 10903 New Hampshire Avenue Document Mail Center - WO66-G609 Silver Spring, MD 20993-0002

Medison Co., Ltd. % Mr. Mark Job Responsible Third Party Official Regulatory Technology Services LLC 1394 25th Street NW BUFFALO MN 55313

DEC 1 0 2009

Re: K093714

Trade/Device Name: SONOACE X8 Diagnostic Ultrasound System Regulation Number: 21 CFR 892.1550 Regulation Name: Ultrasonic pulsed doppler imaging system' Regulatory Class: II Product Code: IYO, IYN, and ITX Dated: December 1, 2009 Received: December 2, 2009

Dear Mr. Job:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and we have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

This determination of substantial equivalence applies to the following transducers intended for use with the SONOACE X8 Diagnostic Ultrasound System, as described in your premarket notification:

Transducer Model Number
3D2-6ETC2-5EPNEV4-9ESP2-4AA
3D4-8EKC2-8HL5-12EDP2-4AH
3D4-8ETC3-7EPL4-7ELP3-5AC
3D4-9ESC4-9/10EDL5-12/50EPP3-7AC
3D5-9EKER4-9/10EDL5-12ECCW 2.0
3DC2-6EV4-9/10EDL5-12EPCW 4.0
C2-5ELNER4-9ESMPT4-7

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Page 2 - Mr. Mark Job

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

This letter will allow you to begin marketing your device as described in your premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus permits your device to proceed to market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please go to http://www.fda.gov/AboutFDA/CentersOffices/CDRHOffices/ucm115809.htm for the Center for Devices and Radiological Health's (CDRH's) Office of Compliance. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to

http://www.fda.gov/MedicalDevices/Safety/ReportaProblem/default.htm for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance.

If you have any questions regarding the content of this letter, please contact Paul Hardy at (301) 796-6542.

Sincerely yours,

Janine M. Morris Acting Director, Division of Reproductive, Abdominal, and Radiological Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure(s)

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Section 1.3 INDICATIONS FOR USE

DIAGNOSTIC ULTRASOUND INDICATIONS STATEMENT
510(k) No.:K093714
Device Name:SONOACE X8 Diagnostic Ultrasound System
Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal (See Note 3)PPPPPNote 1Notes 2, 7, 8
AbdominalPPPPPNote 1Notes 2, 7, 8
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal Imaging& OtherLaparoscopic
PediatricPPPPPNote 1Note 2,4,5,6,7,8,9
Small Organ (See Note 5)PPPPPNote 1Note 2,5,6,8,9
Neonatal CephalicPPPPPNote 1
Adult CephalicPPPPPNote 1Note 4, 7
Trans-rectalPPPPPNote 1Note 2, 3, 8
Trans-vaginalPPPPPNote 1Note 2, 3, 8
Trans-urethral
Trans-esoph. (non-Cardiac)NNNNNNote 1Note 4, 7
Musculo-skel. (Convent.)PPPPPNote 1Note 2,5,6,8,9
Musculo-skel. (Superfic.)PPPPPNote 1Note 2,5,6,8,9
Intra-luminal
Other (spec.)
Cardiac AdultPPPPPNote 1Note 4, 7
CardiacCardiac PediatricPPPPPNote 1Note 4, 7
Trans-esophageal (Cardiac)NNNNNNote 1Note 4, 7
Other (spec.)
PeripheralVesselPeripheral vesselPPPPPNote 1Note 5, 6, 9
Other (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler, B/Power Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scroturn and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Per 21 CFR 801.109)

(Division Sign-Off)
---------------------

Division of Reproductive, Abdominal,
and Radiological Devices

510(k) NumberK093714
------------------------

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510(k) No.:
Device Name:3D2-6ET for use with SONOACE X8
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal (See Note 3)PPPPNote 1Notes 2, 7, 8
AbdominalPPPPNote 1Notes 2, 7, 8
Fetal Imaging& OtherIntra-operative (See Note 6)
Intra-operative (Neuro.)
Laparoscopic
PediatricPPPPNote 1Notes 2, 7, 8
Small Organ (See Note 5)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)
Intra-luminal
Other (spec.)
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (spec.)
Peripheral vessel
PeripheralVesselOther (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Per 21 CFR 801.109)

(Division Sign-Off)
Division of Reproductive, Abdominal,
and Radiological Devices
510(k) Number K93714

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510(k) No .:

3D4-8EK for use with SONOACE X8Device Name:Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows
Clinical ApplicationBMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
General(Track I only)Ophthalmic
Fetal Imaging& OtherFetal (See Note 3)ppppNote 1Notes 2, 7, 8
AbdominalppppNote 1Notes 2, 7, 8
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Laparoscopic
PediatricppppNote 1Notes 2, 7, 8
Small Organ (See Note 5)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)
Intra-luminal
Other (spec.)
CardiacCardiac Adult
Cardiac Pediatric
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralVesselPeripheral vessel
Other (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

  • Note 6: Abdominal organs and peripheral vessel
    Note 7: Tissue Hannonic Imaging (THI)

Note 8: 3D imaging

Note 9: Panoramic imaging

Concurrence of CDRH, Office of Device Evaluation (ODE) Prescription Use (Pey 21 CFR 801.109)

(Division Sign-Off) Division of Reproductive, Abdominal. and Radiological Dev

510(k) Number

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510(k) No.:
Device Name:3D4-8ET for use with SONOACE X8
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
Ophthalmic
Fetal (See Note 3)PPPPNote 1Notes 2, 7, 8
AbdominalPPPPNote 1Notes 2, 7, 8
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal Imaging& OtherLaparoscopic
PediatricPPPPNote 1Notes 2, 7, 8
Small Organ (See Note 5)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)
Intra-luminal
Other (spec.)
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralVesselPeripheral vessel
Other (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Note 9: Panoramic imaging

Concurrence of CDRH, Office of Device Evaluation (ODE) Prescription Use (Per 21 CFR 801.109)

Heleum

(Division Sign-Off) Division of Reproductive, Abdominal. and Radiological I 510(k) Numbe

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510(k) No .: Device Name: 3D4-9ES for use with SONOACE X8 Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows: Intended Use: Clinical Application Mode of Operation (includes simultaneous B-mode) General Specific B M PWD CWD Color Combined Other (Track I only) (Tracks I & III) Doppler* (Spec.) (Spec.) Ophthalmic Ophthalmic Fetal (See Note 3) Abdominal Intra-operative (See Note 6) Intra-operative (Neuro.) Fetal Imaging Laparoscopic Pediatric & Other Small Organ (See Note 5) Neonatal Cephalic Adult Cephalic Trans-rectal P P P P Notes 2, 8 Note 1 Trans-vaginal P P Notes 2, 8 P P Note 1 Trans-urethral Trans-esoph. (non-Cardiac) Musculo-skel. (Convent.) Musculo-skel. (Superfic.) Intra-luminal Other (spec.) Cardiac Adult Cardiac Cardiac Pediatric Trans-esophageal (Cardiac) Other (spec.) Peripheral Peripheral vessel Vessel Other (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler, B/Power Doppler/PW Doppler/PW Doppler. B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Note 9: Panoramic imaging

Concurrence of CDRH, Office of Device Evaluation (ODE) Prescription Use (Per 21 CFR 801.109)

Division Sign Off

(Division Sign-Off) Division of Reproductive, Abdominal, and Radiological Devic 510(k) Number

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510(k) No.:
Device Name:3D5-9EK for use with SONOACE X8
Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal (See Note 3)
Abdominal
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal Imaging& OtherLaparoscopic
Pediatric
Small Organ (See Note 5)
Neonatal Cephalic
Adult Cephalic
Trans-rectalPPPPNote 1Notes 2, 8
Trans-vaginalPPPPNote 1Notes 2, 8
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)
Intra-luminal
Other (spec.)
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralVesselPeripheral vessel
Other (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Note 9: Panoramic imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Rer 21 CFR 801.109)

(Division Sign-Off)
Division of Reproductive, Abdominal,
and Radiological Devices

510(k) Number

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510(k) No .:
Device Name:3DC2-6 for use with SONOACE X8
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal (See Note 3)NNNNNote 1Notes 2, 7, 8
AbdominalNNNNNote lNotes 2, 7, 8
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal ImagingLaparoscopic
& OtherPediatricNNNNNote 1Notes 2, 7, 8
Small Organ (See Note 5)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)
Intra-luminal
Other (spec.)
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralPeripheral vessel
VesselOther (spec.)

N= new indication; P= previously cleared; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Per 21 CFR 801.109)

Hes. Klem

gn-C (fr) (Divisic Division of Reproductive, Abdominal and Radiological D 510(k) Number

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510(k) No .: Device Name: C2-5EL for use with SONOACE X8 Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows: Intended Use: Clinical Application Mode of Operation (includes simultaneous B-mode) General Specific B PWD CWD M Color Combined Other (Track I only) (Tracks I & III) Doppler* (Spec.) (Spec.) Ophthalmic Ophthalmic Fetal (See Note 3) P P P P Note 1 Notes 2, 7, 8 Abdominal P Notes 2, 7, 8 P P P Note l Intra-operative (See Note 6) Intra-operative (Neuro.) Fetal Imaging Laparoscopic & Other Pediatric P P P P Note l Notes 2, 7, 8 Small Organ (See Note 5) Neonatal Cephalic Adult Cephalic Trans-rectal Trans-vaginal Trans-urethral Trans-esoph. (non-Cardiac) Musculo-skel. (Convent.) Musculo-skel. (Superfic.) Intra-luminal Other (spec.) Cardiac Adult Cardiac Cardiac Pediatric Trans-esophageal (Cardiac) Other (spec.) Peripheral Peripheral vessel Vessel Other (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Per 21 CFR 801.109)

Sign-0 Division of Reproductive, Abdominal, and Radiological D 510(k) Number

{12}------------------------------------------------

510(k) No .: Device Name: C2-5EP for use with SONOACE X8 Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows: Intended Use: Clinical Application Mode of Operation (includes simultaneous B-mode) Specific General B M PWD CWD Color Combined Other (Track I only) (Tracks I & III) Doppler3 (Spec.) (Spec.) Ophthalmic Ophthalmic Fetal (See Note 3) N Note 1 Notes 2, 7, 8 N N N Abdominal N N N N Note 1 Notes 2, 7, 8 Intra-operative (See Note 6) Intra-operative (Neuro.) Laparoscopic Fetal Imaging & Other Pediatric N Note 1 Notes 2, 7, 8 N N N Small Organ (See Note 5) Neonatal Cephalic Adult Cephalic Trans-rectal Trans-vaginal Trans-urethral Trans-esoph. (non-Cardiac) Musculo-skel. (Convent.) Musculo-skel. (Superfic.) Intra-luminal Other (spec.) Cardiac Adult Cardiac Cardiac Pediatric Trans-csophagcal (Cardiac) Other (spec.) Peripheral Peripheral vessel Vessel Other (spec.)

N= new indication; P= previously cleared; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Per 21 CFR 801.109)

(Division Sign-Off) Division of Reproductive, Abdominal, and Radiological I 510/k) Number

{13}------------------------------------------------

510(k) No.:
C2-8 for use with SONOACE X8Device Name:
Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:Intended Use:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
GeneralSpecificBMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
(Track I only)(Tracks I & III)
OphthalmicOphthalmic
Fetal (See Note 3)NNNNNote 1Notes 2, 7, 8
AbdominalNNNNNote 1Notes 2, 7, 8
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal Imaging& OtherLaparoscopic
PediatricNNNNNote 1Notes 2, 7, 8
Small Organ (See Note 5)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)
Intra-luminal
Other (spec.)
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralVesselPeripheral vessel
Other (spec.)

N= new indication; P= previously cleared; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler, B/Power Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Per 21 CFR 801.109)

Herlea

(Division Sign-Off) Division of Reproductive, Abdominal and Radiological Dev 510(k) Number

{14}------------------------------------------------

510(k) No.:
Device Name:C3-7EP for use with SONOACE X8
Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
General(Track I only)Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal Imaging& OtherFetal (See Note 3)PPPPNote 1Notes 2, 7, 8
AbdominalPPPPNote 1Notes 2, 7, 8
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Laparoscopic
PediatricPPPPNote 1Notes 2, 7, 8
Small Organ (See Note 5)
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)
Intra-luminal
Other (spec.)
CardiacCardiac Adult
Cardiac Pediatric
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralVesselPeripheral vessel
Other (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Note 9: Panoramic imaging

Concurrence of CDRH, Office of Device Evaluation (ODE) Prescription Use(Per 21 CER 801.109)

Hestum

Sign-Off) (Division Division of Reproductive, Abdominal, and Radiclogical Devi 510(k) Numbe

{15}------------------------------------------------

510(k) No .:
Device Name:C4-9/10ED for use with SONOACE X8
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
GeneralSpecificBMPWDCWDColorCombined*Other
(Track I only)(Tracks I & III)Doppler*(Spec.)(Spec.)
OphthalmicOphthalmic
Fetal (See Note 3)PPPPNote 1Note 2, 8
AbdominalPPPPNote 1Note 2, 8
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal ImagingLaparoscopic
& OtherPediatricPPPPNote lNote 2, 8
Small Organ (See Note 5)PPPPNote lNote 2, 8
Neonatal CephalicPPPPNote 1Note 2, 8
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)
Intra-luminal
Other (spec.)
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralPeripheral vesselPPPPNote 1Note 2, 8
VesselOther (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler, B/Power Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Per 21 CFR 801.109)

(Division Sign-Off) Division of Reproductive, Abdominal, and Radiological Dev 510(k) Number

{16}------------------------------------------------

510(k) No.: Device Name:

Device Name:ER4-9/10ED for use with SONOACE X8
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
GeneralSpecificBMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
(Track I only)(Tracks I & III)
OphthalmicOphthalmic
Fetal (See Note 3)
Abdominal
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal Imaging& OtherLaparoscopic
Pediatric
Small Organ (See Note 5)
Neonatal Cephalic
Adult Cephalic
Trans-rectalPPPPNote 1Note 2, 8
Trans-vaginalPPPPNote 1Note 2, 8
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)1
Intra-luminal
Other (spec.)
CardiacCardiac Adult
Cardiac Pediatric
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralVesselPeripheral vessel
Other (spec.)

N= new indication; P= previously cleared by FDA K092159; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler, B/Power Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Per 21 CFR 801.109)

(Division Sign-Off)
Division of Reproductive, Abdominal,
and Radiological Devices

510(k) NumberK093714
------------------------

{17}------------------------------------------------

PU CHAED C ..

DIAGNOSTIC ULTRASOUND INDICATIONS FOR USE STATEMENT

510(k) No.: Darria AT

Device Traine:E V4->> TULD for use With SONUACE A8Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal (See Note 3)AbdominalIntra-operative (See Note 6)Intra-operative (Neuro.)
Fetal Imaging& OtherLaparoscopicPediatric
Small Organ (See Note 5)Neonatal CephalicAdult Cephalic
Trans-rectalPPPPNote 1Note 2, 8
Trans-vaginalTrans-urethralTrans-esoph. (non-Cardiac)Musculo-skel. (Convent.)Musculo-skel. (Superfic.)Intra-luminalPPPPNote 1Note 2, 8
Other (spec.)
CardiacCardiac AdultCardiac PediatricTrans-esophageal (Cardiac)Other (spec.)
PeripheralVesselPeripheral vesselOther (spec.)

N= new indication; P= previously cleared by FDA K092159; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

  • Note 6: Abdominal organs and peripheral vessel
  • Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)

Prescription Use (Per 21 CFR 801.109)

(Division Sign-Off)
Division of Reproductive, Abdominal,

Radiological Devices

S/N Number: 093714

{18}------------------------------------------------

510(k) No.:
Device Name:NER4-9ES for use with SONOACE X8
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal (See Note 3)
Abdominal
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal Imaging& OtherLaparoscopic
Pediatric
Small Organ (See Note 5)
Neonatal Cephalic
Adult Cephalic
Trans-rectalPPPPNote 1Note 2, 8
Trans-vaginalPPPPNote 1Note 2, 8
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)
Intra-luminal
Other (spec.)
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralVesselPeripheral vessel
Other (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescriptiop Use (Per 2Y CFR 801.109)

(Division Sign-Off)

Division of Reproductive, Abdominal, and Radiological D 510(k) Number

{19}------------------------------------------------

510(k) No.:
Device Name: NEV4-9ES for use with SONOACE X8
Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
Ophthalmic
Fetal Imaging& OtherFetal (See Note 3)
Abdominal
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Laparoscopic
Pediatric
Small Organ (See Note 5)
Neonatal Cephalic
Adult Cephalic
Trans-rectalPPPPNote 1Note 2, 8
Trans-vaginalPPPPNote 1Note 2, 8
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)
Intra-luminal
Other (spec.)
CardiacCardiac Adult
Cardiac Pediatric
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralVesselPeripheral vessel
Other (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppier/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Per 21 CFR 801.109)
(Division Sign-Off)
Division of Reproductive, Abdominal, and Radiological Devices
510(k) NumberK093714

{20}------------------------------------------------

510(k) No.:
Device Name:HL5-12ED for use with SONOACE X8
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal (See Note 3)
Abdominal
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal Imaging& OtherLaparoscopic
PediatricPPPPNote 1Note 2, 5, 6, 7, 9
Small Organ (See Note 5)PPPPNote 1Note 2, 5, 6, 7, 9
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)PPPPNote 1Note 2, 5, 6, 7, 9
Musculo-skel. (Superfic.)PPPPNote 1Note 2, 5, 6, 7, 9
Intra-luminal
Other (spec.)
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralVesselPeripheral vesselPPPPNote 1Note 2, 5, 6, 7, 9
Other (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler, B/Power Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Note 9: Panoramic imaging

Concurrence of CDRH, Qffice of Device Evaluation (ODE) Prescription Use (Per 21 CFR 801.109)

Hul

(Division Sign-Off) Division of Reproductive, Abdominal, and Radiological De 510(k) Number

{21}------------------------------------------------

510(k) No.:
Device Name:L4-7EL for use with SONOACE X8
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal (See Note 3)
Abdominal
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal Imaging& OtherLaparoscopic
PediatricPPPPNote 1Note 2, 5, 6, 7, 9
Small Organ (See Note 5)PPPPNote 1Note 2, 5, 6, 7, 9
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)PPPPNote 1Note 2, 5, 6, 7, 9
Musculo-skel. (Superfic.)PPPPNote 1Note 2, 5, 6, 7, 9
Intra-luminal
Other (spec.)
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralVesselPeripheral vesselPPPPNote 1Note 2, 5, 6, 7, 9
Other (spec.)

N= new indication; P= previously cleared by FDA K092159; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Note 9: Panoramic imaging

Concurrence of CDRH, Office of Device Evaluation (ODE) Prescription Use (Per 21 CFR 801.109)

(Division Sign-Off) Division of Reproductive, Abdominal, and Radiological Dey 510(k) Number

{22}------------------------------------------------

510(k) No .:
Device Name:L5-12/50EP for use with SONOACE X8
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal (See Note 3)AbdominalIntra-operative (See Note 6)Intra-operative (Neuro.)
Fetal ImagingLaparoscopic
& OtherPediatricPPPpNote 1Note 2, 5, 6, 7, 9
Small Organ (See Note 5)PPPPNote lNote 2, 5, 6, 7, 9
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)PPPPNote lNote 2, 5, 6, 7, 9
Musculo-skel. (Superfic.)PPPPNote lNote 2, 5, 6, 7, 9
Intra-luminal
Other (spec.)
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralPeripheral vesselPPpPNote 1Note 2, 5, 6, 7, 9
VesselOther (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Note 9: Panoramic imaging

Concurrence of CDRH, Office of Device Evaluation (ODE) Prescription Use (Per 2) CFR 801.109)

signature

(Division Sign-Off) Division of Reproductive, Abdominal, and Radiological 510(k) Number

{23}------------------------------------------------

510(k) No.:
Device Name: L5-12EC for use with SONOACE X8
Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColor Doppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal (See Note 3)
Abdominal
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal Imaging& OtherLaparoscopic
PediatricPPPPNote 1Note 2, 5, 6, 7, 9
Small Organ (See Note 5)PPPPNote 1Note 2, 5, 6, 7, 9
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)PPPPNote 1Note 2, 5, 6, 7, 9
Musculo-skel. (Superfic.)PPPPNote 1Note 2, 5, 6, 7, 9
Intra-luminal
Other (spec.)
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralVesselPeripheral vesselPPPPNote 1Note 2, 5, 6, 7, 9
Other (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)

Prescription Use (Per21 CFR 801.109)

(Division Sign-Off) Division of Reproductive, Abdominal, and Radiological De 510(k) Number

{24}------------------------------------------------

510(k) No.:
Device Name:L5-12EP for use with SONOACE X8
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
GeneralSpecificBMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
(Track I only)(Tracks I & III)
OphthalmicOphthalmic
Fetal (See Note 3)
Abdominal
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal Imaging& OtherLaparoscopic
PediatricNNNNNote 1Note 2, 5, 6, 7, 9
Small Organ (See Note 5)NNNNNote 1Note 2, 5, 6, 7, 9
Neonatal Cephalic
Adult Cephalic
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)NNNNNote 1Note 2, 5, 6, 7, 9
Musculo-skel. (Superfic.)NNNNNote 1Note 2, 5, 6, 7, 9
Intra-luminal
Other (spec.)
Cardiac Adult
CardiacCardiac Pediatric
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralVesselPeripheral vesselNNNNNote 1Note 2, 5, 6, 7, 9
Other (spec.)

N= new indication; P= previously cleared; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription/Use (Per 21CFR 801.109)

(Division Sign-Off) Division of Reproductive, Abdominal, and Radiological D 510(k) Number

{25}------------------------------------------------

510(k) No .: Device Name: MPT4-7 for use with SONOACE X8 Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows: Clinical Application Mode of Operation (includes simultaneous B-mode) General Specific B M PWD CWD Color Combined Other (Track I only) (Tracks I & III) Doppler* (Spec.) (Spec.) Ophthalmic Ophthalmic Fetal (See Note 3) Abdominal Intra-operative (See Note 6) Intra-operative (Neuro.) Fetal Imaging Laparoscopic & Other Pediatric Small Organ (See Note 5) Neonatal Cephalic Adult Cephalic Trans-rectal Trans-vaginal Trans-urethral Trans-esoph. (non-Cardiac) P P P P P Note l Note 7, 8 Musculo-skel. (Convent.) Musculo-skel. (Superfic.) Intra-luminal Other (spec.) Cardiac Adult Cardiac Cardiac Pediatric Trans-esophageal (Cardiac) P P P P P Note l Note 7, 8 Other (spec.) Peripheral Peripheral vessel Vessel Other (spec.)

N= new indication; P= previously cleared by FDA K092159; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Per 21 CFR 801.109)

(Division Sign-Off)
Division of Reproductive, Abdominal,
and Radiological Devices
510(k) Number K093714

{26}------------------------------------------------

510(k) No.:
Device Name:P2-4AA for use with SONOACE X8
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal (See Note 3)
AbdominalNNNNNNote 1Note 4, 7
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal Imaging& OtherLaparoscopic
Pediatric
Small Organ (See Note 5)
Neonatal Cephalic
Adult CephalicNNNNNNote 1Note 4, 7
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)
Intra-luminal
Other (spec.)
Cardiac AdultNNNNNNote 1Note 4, 7
CardiacCardiac PediatricNNNNNNote 1Note 4, 7
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralVesselPeripheral vessel
Other (spec.)

N= new indication; P= previously cleared; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Per 21 CER 801.109)

vision Sign-Off

(Division/Sign-Off)
Division of Reproductive, Abdominal,
and Radiological Devices
510(k) Number K093714

{27}------------------------------------------------

510(k) No .:

Device Name: P2-4AH for use with SONOACE X8 Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows: Intended Use:

Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal (See Note 3)
AbdominalPPPPPNote 1Note 4, 7
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal Imaging& OtherLaparoscopic
Pediatric
Small Organ (See Note 5)
Neonatal Cephalic
Adult CephalicPPPPPNote 1Note 4, 7
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)
Intra-luminal
Other (spec.)
Cardiac AdultPPPPPNote 1Note 4, 7
CardiacCardiac PediatricPPPPPNote 1Note 4, 7
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralVesselPeripheral vessel
Other (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note I: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler, B/Power Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Note 9: Panoramic imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Per 21 CFR 801.109)

(Division Sign-Off)

roductive Andominal

510(k) Number

{28}------------------------------------------------

510(k) No .:
Device Name:P3-5AC for use with SONOACE X8
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
GeneralSpecificBMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
(Track I only)(Tracks I & III)
OphthalmicOphthalmic
Fetal (See Note 3)
AbdominalPPPPPNote 1Note 4, 7
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal ImagingLaparoscopic
& OtherPediatric
Small Organ (See Note 5)
Neonatal Cephalic
Adult CephalicPPPPPNote 1Note 4, 7
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)
Intra-luminal
Other (spec.)
Cardiac AdultPPPPPNote 1Note 4, 7
CardiacCardiac PediatricPPPPPNote 1Note 4, 7
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralPeripheral vessel
VesselOther (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Per/21 CFR 801.109)

Hed

(Division Sign-Off)
Division of Reproductive, Abdominal,
and Radiological Devices,

510(k) Number K01211

{29}------------------------------------------------

510(k) No.:

510(k) No.:P3-7AC for use with SONOACE X8
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
Ophthalmic
Fetal (See Note 3)
AbdominalPPPPPNote 1Note 4, 7
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal Imaging& OtherLaparoscopic
Pediatric
Small Organ (See Note 5)
Neonatal Cephalic
Adult CephalicPPPPPNote 1Note 4, 7
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)
Intra-luminal
Other (spec.)
CardiacCardiac AdultPPPPPNote 1Note 4, 7
Cardiac PediatricPPPPPNote 1Note 4, 7
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralVesselPeripheral vessel
Other (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler, B/Power Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Per 21 CFR 801.109)

Reproductive, Abdominal, and Radiological 510(k) Numbe

{30}------------------------------------------------

510(k) No.:
Device Name:CW 2.0 for use with SONOACE X8
Intended Use:Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:
Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
General(Track I only)Specific(Tracks I & III)BMPWDCWDColorDoppler*Combined*(Spec.)Other(Spec.)
OphthalmicOphthalmic
Fetal (See Note 3)
Abdominal
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal Imaging& OtherLaparoscopic
Pediatric
Small Organ (See Note 5)
Neonatal Cephalic
Adult CephalicP
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)
Intra-luminal
Other (spec.)
Cardiac AdultP
CardiacCardiac PediatricP
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralVesselPeripheral vesselP
Other (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Per 21 CFR 801.109)

Signature of

teproductive, Abdominal,

{31}------------------------------------------------

510(k) No .:

Device Name: CW 4.0 for use with SONOACE X8 Intended Use: Diagnostic ultrasound imaging or fluid flow analysis of the human body as follows:

Clinical ApplicationMode of Operation (*includes simultaneous B-mode)
GeneralSpecificBMPWDCWDColorCombined*Other
(Track I only)(Tracks I & III)Doppler*(Spec.)(Spec.)
OphthalmicOphthalmic
Fetal (See Note 3)
Abdominal
Intra-operative (See Note 6)
Intra-operative (Neuro.)
Fetal ImagingLaparoscopic
& OtherPediatricP
Small Organ (See Note 5)
Neonatal Cephalic
Adult CephalicP
Trans-rectal
Trans-vaginal
Trans-urethral
Trans-esoph. (non-Cardiac)
Musculo-skel. (Convent.)
Musculo-skel. (Superfic.)
Intra-luminal
Other (spec.)
CardiacCardiac AdultP
Cardiac PediatricP
Trans-esophageal (Cardiac)
Other (spec.)
PeripheralPeripheral vesselP
VesselOther (spec.)

N= new indication; P= previously cleared by FDA K063580; E= added under Appendix E

Additional Comments:

Color Doppler includes Power (Amplitude) Doppler

Note 1: B/M, B/PW Doppler, B/Color Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler/PW Doppler, B/Color Doppler/Color M

Note 2: Includes imaging for guidance of biopsy

Note 3: Includes infertility monitoring of follicle development

Note 4: Color M-mode

Note 5: For example: thyroid, parathyroid, breast, scrotum and penis in adult, pediatric and neonatal patients

Note 6: Abdominal organs and peripheral vessel

Note 7: Tissue Harmonic Imaging (THI)

Note 8: 3D imaging

Concurrence of CDRH, Office of Device Evaluation (ODE)
Prescription Use (Per 21 CFR 801.109)

Division Sign-Off

Division of Reproductive, Abdominal,
and Radiological Devices

§ 892.1570 Diagnostic ultrasonic transducer.

(a)
Identification. A diagnostic ultrasonic transducer is a device made of a piezoelectric material that converts electrical signals into acoustic signals and acoustic signals into electrical signals and intended for use in diagnostic ultrasonic medical devices. Accessories of this generic type of device may include transmission media for acoustically coupling the transducer to the body surface, such as acoustic gel, paste, or a flexible fluid container.(b)
Classification. Class II.