K Number
K091415
Date Cleared
2009-09-04

(114 days)

Product Code
Regulation Number
870.1130
Reference & Predicate Devices
Predicate For
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

Truly Automatic Wrist Blood Pressure Monitor ,Models DW100, DW200, DW500, DW700, DW701M, DW702M, DW703 are a series devices intended to measure the systolic and diastolic blood pressure and pulse rate of an adult individual by using a non-invasive technique in which an inflatable cuff is wrapped around the wrist.

The devices features include irregular pulse rhythm detection during measurement. and display a warning signal with the reading once the irregular heartbeat is detected.

Device Description

Truly Automatic Wrist Blood Pressure Monitor DW series, Models DW100, DW200, DW500, DW700, DW701M, DW702M, DW703 are designed to measure the systolic and diastolic blood pressure and pulse rate of an individual by using a non-invasive technique in which an inflatable cuff is wrapped around the wrist.

Our method to define systolic and diastolic pressure is similar to the auscultatory method but uses an electronic pressure sensor rather than a stethoscope and mercury manometer. The sensor converts tiny alterations in cuff pressure to electrical signals, by analyzing those signals to define the systolic and diastolic blood pressure and calculating pulse rate, which is a well-known technique in the market called the "oscillometric method".

Truly Automatic Wrist Blood Pressure Monitor DW series are single-mounted devices of the main unit and cuff unit. ABS is used to outer housing of the main unit. The preformed cuff unit, which is applicable to wrist circumfernan approximately between 135 and 220 mm, includes the inflatable bladder and nylon shell. All models of the wrist blood pressure monitor use a single size of cuff. The device consists of the microprocessor, the pressure sensor, the operation keys, the pump, the electromagnetic deflation control valve and the LCD. The subject devices are powered by two AAA alkaline batteries.

The device also compares the longest and the shortest time intervals of detected pulse waves to mean time interval and displays a warning signal with the reading to indicate the detection of irregular pulse rhythm when the difference of the time intervals is over 25%.

AI/ML Overview

Here's an analysis of the provided text regarding the acceptance criteria and study for the Truly Automatic Wrist Blood Pressure Monitor DW series:

1. Table of Acceptance Criteria and Reported Device Performance

The document explicitly states the accuracy acceptance criteria for both pressure and pulse rate measurements.

ParameterAcceptance CriteriaReported Device Performance
Accuracy (Pressure)± 3 mmHg± 3 mmHg (Stated as "No change, all same" compared to predicate device K014141, which had this accuracy)
Accuracy (Pulse)± 5%± 5% (Stated as "No change, all same" compared to predicate device K014141, which had this accuracy)

2. Sample Sizes Used for the Test Set and Data Provenance

The document does not explicitly state the sample size used for the test set or the data provenance (e.g., country of origin, retrospective/prospective). It only mentions that the measurement methods are "No change, all same" as the predicate devices, implying that their performance is expected to be similar.

3. Number of Experts Used to Establish the Ground Truth for the Test Set and Qualifications of Those Experts

The document does not provide information on the number of experts used or their qualifications for establishing ground truth for any tests performed specifically for this device. Blood pressure monitor studies typically compare device readings against reference measurements taken by trained professionals using a mercury sphygmomanometer, but this specific information is absent.

4. Adjudication Method for the Test Set

The document does not describe any adjudication method used for the test set.

5. Multi-Reader Multi-Case (MRMC) Comparative Effectiveness Study

No. The document does not mention a multi-reader multi-case (MRMC) comparative effectiveness study. Blood pressure monitors are typically assessed for agreement with a gold standard, not for their impact on human reader performance.

6. Standalone (Algorithm Only) Performance Study

Yes, implicitly. The listed "Accuracy Pressure" and "Accuracy Pulse" of ±3 mmHg and ±5% respectively are standalone performance metrics of the device's algorithm and hardware, without human intervention in the measurement process itself, beyond initiation. The document states that the calibration and measurement algorithms are the same ("No change, all same") as the predicate device K014141, which itself would have undergone standalone performance testing to meet its accuracy claims.

7. Type of Ground Truth Used

The document inherently refers to the auscultatory method as the ground truth. It states, "Our method to define systolic and diastolic pressure is similar to the auscultatory method but uses an electronic pressure sensor rather than a stethoscope and mercury manometer." While not explicitly detailed for this specific device's testing, the standard for validating oscillometric blood pressure monitors involves comparing their readings against those obtained by trained observers using a mercury sphygmomanometer (auscultatory method).

8. Sample Size for the Training Set

The document does not provide any information about the sample size used for a training set. This is typical for oscillometric blood pressure monitors, which often rely on well-established algorithms that may have been developed and validated over many years, rather than requiring re-training on new data for each new device model. The document states the measurement algorithm is "No change, all same" as the predicate.

9. How the Ground Truth for the Training Set Was Established

The document does not provide any information on how the ground truth for a training set was established. Given that the measurement algorithm is stated as "No change, all same" as the predicate device (Digibio Digital Blood Pressure Monitor, Model D11), it implies that the core algorithm was previously established and validated with a ground truth likely derived from the auscultatory method. The only detail provided is on the irregular heartbeat detection algorithm, where it refers to a "Software validation report I-5. Algorithm description 4. Determination method of irregular heartbeat," which would presumably detail its development and validation, but this report is not included.

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K091415

510(k) Summary

Date of Summary Preparation: 4.20.2009

SFP - 4 2009

1. Submitter's Identifications

Submitter's Name: Truly Instrument Limited

Address: Truly Industrial Area, Shanwei City, Guangdong Province China Contact Person:___ Manager Yang Jian-Hao Telephone: 86-0660-3380070 Fax: 86-0660-3380377

2. Name of the Device

Device Classification Name: System, Measurement, Blood-Pressure, 1

Non-invasive

Models: DW100, DW200, DW500, DW700, DW701M, DW702M, DW703 Classification Panel: cardio-vascular Common/Usual Name: Automatic Wrist Blood Pressure Monitor Product Code: DXN Device Classification: Class II Contraindications : N/A

3. The Perdicate Devices

a. Digibio Digital Blood Pressure Monitor, Model D11, K014141

  • b. Microlife Wrist Watch Blood Pressure Monitor, Model BP3MK1-3 (BPW100), K073398

4. Device Description

Truly Automatic Wrist Blood Pressure Monitor DW series, Models DW100, DW200, DW500, DW700, DW701M, DW702M, DW703 are designed to measure the systolic and diastolic blood pressure and pulse rate of an individual by using a non-invasive technique in which an inflatable cuff is wrapped around the wrist.

Our method to define systolic and diastolic pressure is similar to the auscultatory method but uses an electronic pressure sensor rather than a stethoscope and mercury manometer. The sensor converts tiny alterations in cuff pressure to electrical signals, by analyzing those signals to define the systolic and diastolic blood pressure and calculating pulse rate, which is a well-known technique in the market called the "oscillometric method".

Truly Automatic Wrist Blood Pressure Monitor DW series are single-mounted devices of the main unit and cuff unit. ABS is used to outer housing of the main unit. The preformed cuff unit, which is applicable to wrist circumfernan approximately between 135 and 220 mm, includes the inflatable bladder and

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nylon shell. All models of the wrist blood pressure monitor use a single size of cuff. The device consists of the microprocessor, the pressure sensor, the operation keys, the pump, the electromagnetic deflation control valve and the LCD. The subject devices are powered by two AAA alkaline batteries.

The device also compares the longest and the shortest time intervals of detected pulse waves to mean time interval and displays a warning signal with the reading to indicate the detection of irregular pulse rhythm when the difference of the time intervals is over 25%.

5. Intended use of device

Truly Automatic Wrist Blood Pressure Monitor DW series, Models DW100, DW200, DW500, DW700, DW701M, DW702M, DW703 are a series devices intended to measure the systolic and diastolic blood pressure and pulse rate of an adult individual by using a non-invasive technique in which an inflatable cuff is wrapped around the wrist.

The devices features include irregular pulse rhythm detection during measurement, and display a warning signal with the reading once the irregular heartbeat is detected.

6. Summary of Substantial Equivalence

Table 1: The difference between Truly Automatic Wrist Blood Pressure Monitor DW series and Digibio Digital Blood Pressure Monitor, Model D11.

ParameterPredicateDevices D11DW100DW200DW500DW700DW701MDW702MDW703
MeasurementalgorithmMethodOscillometricmethodNo change ,all same
Measurementsite of bodyArmWrist
Pressure SensorMPS-2107No change ,all same
CuffArm cuffWrist cuff.
SoftwareD11 software + Irregular heartbeat detection.
IrregularheartbeatdetectionMore than ±25% to the mean interval of pulse intervals:About the more detailed description of the IH detection algorithm,please refer to "Software validation report I-5. Algorithm description4. Determination method of irregular heartbeat".DW701M, DW702M and DW703 have the IH feature.
Memory Size2 x 602 x 602 x 601 x 991 x 994 x 994 x 991 x 99
MeasurementPressure Range20 ~ 280 mmHgNo change ,all same
MeasurementPulse Range40 ~ 195beats/minNo change ,all same
Measuring1 mmHgNo change ,all same

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21

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ParameterPredicateDevices D11DW100DW200DW500DW700DW701MDW702MDW703
resolution
AccuracyPressure$\pm$ 3mmHgNo change ,all same
Accuracy Pulse$\pm$ 5%No change ,all same
PressurizationSourceAutomaticinternal pumpNo change ,all same
Cuff DeflationAutomaticdeflationNo change ,all same
OperatingEnvironment1040℃1590%RHNo change ,all same
Power4X 1.5V AAA2 x 1.5V AAA
Hardware powercircuit6V powervoltage changeto 4V3V power voltage change to 4V
Hardware othercircuitNo change ,all same
Electronicelement(power circuit)DC-DC BL8503and relationelementDC-DC BL8530 and relation element
Electronicelement(other circuit)No change ,all same
PCBdifferenceThere is difference from D11, but all PCB are same in the wrist bloodpressure monitor DW series.
Display TypeLiquid crystaldisplayNo change ,all same
CoverDifference

Table 2: The difference between Truly Automatic blood pressure monitor DW series and Microlife Wrist Watch Blood Pressure Monitor, Model BP3MK1-3 (BPW100).

ParameterPredicate DevicesBP3MK1-3(BPW100)DW100DW200DW500DW700DW701MDW702MDW703
MeasurementMethodOscillometricMethodNo change - the same
Pressure SensorCapacitiveNo change - the same
MeasurementRange: BP30~280mmHg20 ~ 280 mmHg
MeasurementRange: BP40~200 beats/min40 ~ 195 beats/min

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ParameterPredicate DevicesBP3MK1-3(BPW100)DW100DW200DW500DW700DW701MDW702MDW703
Measuringresolution1mmHgNo change - the same
AccuracyPressure±3mmHgNo change - the same
AccuracyPulse±5%No change - the same
PressurizationSourceAutomatic internalpumpNo change - the same
Cuff DeflationAutomatic deflationNo change - the sameNo change - the sameNo change - the sameNo change - the sameNo change - the sameNo change - the sameNo change - the same
Memory Size992 × 602 × 601 × 991 × 994 × 994 × 991 × 99
Irregular HeartbeatDetectionMore than ±25% tothe mean interval ofpulse intervalsDW701M, DW702M and DW703 have the IH feature.
Power Source2 X1.5V AAAbatteriesNo change - the same
OperatingEnvironment1040℃1590%RHNo change - the same
Cuff AttachmentMethodBy plastic hoseconnected tomonitorNo change - the same
Display TypeLiquidcrystaldisplayLiquid crystal display

7. Conclusions

The subject devices have all features of the predicate device D11 except the new features of irregular heartbeat detection, wrist cuff and the battery power. These differences do not affect the safety and effectiveness of the subject devices.

l rregular heartbeat detection technology is same as what is used Microlife Wrist Watch Blood Pressure Monitor, Model BP3MK1-3 (BPW100), K073398.

Thus, the subject devices are substantially equivalent to the predicate devices.

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DEPARTMENT OF HEALTH & HUMAN SERVICES

Image /page/4/Picture/1 description: The image shows the seal for the Department of Health & Human Services - USA. The seal is circular with the text "DEPARTMENT OF HEALTH & HUMAN SERVICES-USA" around the perimeter. In the center of the seal is an abstract image of an eagle.

Public Health Service

Food and Drug Administration 10903 New Hampshire Avenue Document Control Room -WO66-G609 Silver Spring, MD 20993-0002

Truly Instrument Co., Ltd. c/o Mr. Yang Jian-Hao Manager Truly Industrial Area Shanwei. Guangdong 516600 China

SEP - 4 2009

Re: K091415

Trade/Device Name: Truly Automatic Wrist Blood Pressure Monitor Models DW100. DW200, DW500, DW700, DW701M, DW702M and DW703 Regulatory Number: 21 CFR 870.1130 Regulation Name: Noninvasive Blood Pressure Measurement System Regulatory Class: Class II (Two) Product Code: DXN Dated: Undated Received: August 7, 2009

Dear Mr. Yang:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general confrols provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

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Page 2 - Mr. Yang Jian-Hao

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); medical device reporting (reporting of medical device-related adverse events) (21 CFR 803); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please go to http://www.fda.gov/AboutFDA/CentersOffices/CDRH/CDRHOffices/ucm115809.htm for the Center for Devices and Radiological Health's (CDRH's) Office of Compliance. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to

http://www.fda.gov/MedicalDevices/Safety/ReportaProblem/default.htm for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance.

You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 796-7100 or at its Internet address http://www.fda.gov/MedicalDevices/Resourcesfor You/Industry/default.htm.

Sincerely yours,

Bram D. Zuckerman, M.D. Director Division of Cardiovascular Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

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TRULY®

Indication for Use

510(k) Number (if known):

Device Name: Truly Automatic Wrist Blood Pressure Monitor DW Series, Models DW100,DW200,DW500,DW700,DW701M,DW702M,DW703

Indication For Use:

Truly Automatic Wrist Blood Pressure Monitor ,Models DW100, DW200, DW500, DW700, DW701M, DW702M, DW703 are a series devices intended to measure the systolic and diastolic blood pressure and pulse rate of an adult individual by using a non-invasive technique in which an inflatable cuff is wrapped around the wrist.

The devices features include irregular pulse rhythm detection during measurement. and display a warning signal with the reading once the irregular heartbeat is detected.

Prescription Use

OR Over the Counter Use

(21 CFR Part 801 Subpart D)

(21 CFR Part 801 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE; CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of In Vitro Diagnostic Device Evaluation and Safety (OIVD)

W.M.D.

Division Sign-Off Office of In Vitro Diagnostic Device Evaluation and Safety

510(k) K091415

HongKong: 2/F, Chung Shun Knitting Centre, 1-3 Wing Yip Street, Kwai Chung, N.T., Hong Kong, TEL: (852) 2487 9803 (20 Lines) FAX: (852) 2146 5756 URL: http://www.trulyinstrument.com E-MAIL: healthcare@truly.com.hk China: Truly Industrial Area .ShanWei City. Guangdong Province ,China . TEL:86-0660-3380070 FAX · 86- 0660- 33 803 77

§ 870.1130 Noninvasive blood pressure measurement system.

(a)
Identification. A noninvasive blood pressure measurement system is a device that provides a signal from which systolic, diastolic, mean, or any combination of the three pressures can be derived through the use of tranducers placed on the surface of the body.(b)
Classification. Class II (performance standards).