K Number
K091395
Date Cleared
2009-06-05

(25 days)

Product Code
Regulation Number
870.1025
Reference & Predicate Devices
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

Indicated for use by health care professionals whenever there is a need for monitoring the physiological parameters of patients. Intended for monitoring and recording of and to generate alarms for multiple physiological parameters of adults, pediatrics and neonates in hospital environments. The MP5 is also intended for use in transport situations within and outside of hospital environments.

Device Description

The Philips IntelliVue MP5 Patient Monitor is a device for monitoring and recording of and to generate alarms for, multiple physiological parameters. The modification is the introduction of software release G.1.

AI/ML Overview

Here's a summary of the acceptance criteria and study information based on the provided text for the Philips IntelliVue MP5 Patient Monitor:

1. Table of Acceptance Criteria and Reported Device Performance

The provided document does not contain a specific table detailing quantitative acceptance criteria and corresponding reported device performance metrics. Instead, it states:

Criterion TypeDetails
Acceptance Criteria"Pass/Fail criteria were based on the specifications cleared for the predicate device."
Device Performance"Test results showed substantial equivalence. The results demonstrate that the Philips IntelliVue MP5 Patient Monitor meets all reliability requirements and performance claims."

2. Sample Size Used for the Test Set and Data Provenance

The document does not specify the sample size used for the test set or the data provenance (e.g., country of origin, retrospective or prospective). It simply mentions "Verification, validation, and testing activities."

3. Number of Experts Used to Establish Ground Truth for the Test Set and Qualifications

The document does not provide information about the number of experts used to establish ground truth or their qualifications.

4. Adjudication Method for the Test Set

The document does not specify any adjudication method used for the test set.

5. Multi-Reader Multi-Case (MRMC) Comparative Effectiveness Study

No multi-reader multi-case (MRMC) comparative effectiveness study is mentioned in the provided text, nor is there any discussion of an effect size for human readers improving with or without AI assistance. The device is a patient monitor, not an AI-assisted diagnostic tool in the sense of image interpretation.

6. Standalone (Algorithm Only) Performance Study

The document describes "system level and regression tests as well as testing from the hazard analysis" to establish performance, functionality, and reliability. This implies standalone testing of the software (algorithm only) as part of the system, but specific details or dedicated "standalone study" results are not provided beyond the general statement of meeting requirements.

7. Type of Ground Truth Used

The document implies that the ground truth for testing was based on "specifications cleared for the predicate device" and "reliability requirements and performance claims." This suggests internal engineering specifications and expected performance, rather than external expert consensus, pathology, or outcomes data in a clinical trial sense.

8. Sample Size for the Training Set

The document does not mention any training set or its sample size. This is a software update for a patient monitor, and the testing described focuses on verification and validation against established specifications, not on an AI model that requires a distinct training phase.

9. How the Ground Truth for the Training Set Was Established

Since no training set is mentioned, there is no information on how its ground truth was established.

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KO91395

This summary of 510(k) safety and effectiveness information is submitted in accordance with the requirements of the Safe Medical Devices Act of 1990 and 21 C.F.R. §807.92.

    1. The submitter of this premarket notification is:
      JUN - 5 2009

Andreas Suchi Philips Medizin Systeme Boeblingen GmbH Hewlett-Packard-Str. 2 D-71034 Boeblingen, Germany Tel: ++49 7031 463-1291 Fax: ++49 7031 463-2442 e-mail: andreas.suchi@philips.com.

This summary was prepared on May 8, 2009.

    1. The name of the device is the Philips IntelliVue MP5 Patient Monitor.
      Classification names are as follows:
Device PanelClassificationProCodeDescription
CardiovascularDevices$870.1025, IIDSIDetector and alarm, arrhythmia
$870.1025, IIMLDMonitor, ST Segment with Alarm
$870.1025, IIMHXMonitor, Physiological, Patient(with arrhythmia detection oralarms)
$870.1100, IIDSJAlarm, Blood Pressure
$870.1110, IIDSKComputer, Blood Pressure
$870.1130, IIDXNSystem, Measurement, Blood-Pressure, Non-Invasive
$870.1435, IIDXGComputer, Diagnostic, Pre-Programmed, Single-Function
$870.1915, IIKRBProbe, Thermodilution
$870.2060, IIDRQAmplifier and SignalConditioner, Transducer Signal
$870.2300, IIDRTMonitor, Cardiac (incl.Cardiotachometer & Rate Alarm)
$870.2340, IIDPSElectrocardiograph
$870.2340, IIMLCMonitor, ST Segment
$870.2350, IIDRWElectrocardiograph, LeadSwitching Adapter
$870.2370, IIKRCTester, Electrode, Surface,Electrocardiograph
$870.2600, IDRJSystem, Signal Isolation
$870.2700, IIDQAOximeter
$870.2770, IIDSBPlethysmograph, Impedance
$870.2800, IIDSHRecorder, Magnetic tape,Medical
$870.2810, IDSFRecorder, Paper Chart
$870.2850, IIDRSExtravascular Blood PressureTransducer
$870.2900, IDSACable, Transducer andElectrode, incl. PatientConnector
Device PanelClassificationProCodeDescription
-MSXSystem, Network andCommunication, PhysiologicalMonitors
$870.2910, IIDRGTransmitters and Receivers,Physiological Signal,Radiofrequency
AnesthesiologyDevices$868.1400, IICCKAnalyzer, Gas, Carbon Dioxide,Gaseous-Phase
$868.1500, IICBQAnalyzer, Gas, Enflurane,Gaseous-Phase (AnestheticConcentration)
$868.1500, IINHOAnalyzer, Gas, Desflurane,Gaseous-Phase (AnestheticConcentration)
$868.1500, IINHPAnalyzer, Gas, Sevoflurane,Gaseous-Phase (AnestheticConcentration)
$868.1500, IINHQAnalyzer, Gas, Isoflurane,Gaseous-Phase (AnestheticConcentration)
$868.1620, IICBSAnalyzer, Gas, Halothane,Gaseous-Phase (AnestheticConcentration)
$868.1700, IICBRAnalyzer, Gas, Nitrous Oxide,Gaseous-Phase (AnestheticConcentration)
$868.1720, IICCLAnalyzer, Gas, Oxygen, Gaseous-Phase
$868.1880, IIBZCData calculator Pulmonary-function
$868.2375, IIBZQMonitor, Breathing Frequency
$868.2480, IILKDMonitor, Carbon Dioxide,Cutaneous
$868.2500, IIKLKMonitor, Oxygen, Cutaneous, forInfant not under Gas Anesthesia
General Hospitaland Personal UseDevices$880.2910, IIFLLThermometer, Electronic,Clinical
NeurologicalDevices$882.1400, IIGWRElectroencephalograph
Devices$882.1420, IGWSAnalyzer, Spectrum,Electroencephalogram Signal

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    1. The modified devices are substantially equivalent to previously cleared Philips IntelliVue MP5 Patient Monitor marketed pursuant to K062392, K063725, K71426, K81793, K082633, and K083228.
    1. The modification is the introduction of software release G.1 for the Philips IntelliVue MP5 Patient Monitor.
    1. The modified device has the same intended use as the legally marketed predicate device. The Philips IntelliVue MP5 Patient Monitor is intended for monitoring and recording of and to generate alarms for, multiple physiological parameters of adults, pediatrics and neonates in hospital environments. The MP5 is additionally intended for use in transport situations

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within and outside of hospital environments. The monitor is not intended for home use. It is intended for use by health care professionals.

    1. The modified device has the same technological characteristics as the legally marketed predicate device.
    1. Verification, validation, and testing activities establish the performance, functionality, and reliability characteristics of the modified device with respect to the predicate. Testing involved system level and regression tests as well as testing from the hazard analysis. Pass/Fail criteria were based on the specifications cleared for the predicate device and test results showed substantial equivalence. The results demonstrate that the Philips IntelliVue MP5 Patient Monitor meets all reliability requirements and performance claims.

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Image /page/3/Picture/0 description: The image shows the logo for the U.S. Department of Health and Human Services. The logo features a stylized eagle with its wings spread, and the text "DEPARTMENT OF HEALTH & HUMAN SERVICES • USA" is arranged in a circular pattern around the eagle. The eagle is black, and the text is in a sans-serif font.

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

JUN - 5 2009

Philips Medizin Systeme Boeblingen GMBH Mr. Andreas Suchi Senior Regulatory Affairs Engineer Philips Healthcare Hewlett-Packard -Str. 2 D-71034 Boeblingen, Germany

Re: K091395

Trade/Device Name: Philips IntelliVue MP5 Patient Monitor, Software Version G.1 Regulation Number: 21 CFR 870.1025 Regulation Name: Arrhythmia Detector and Alarm (including ST-segment measurement and alarm) Regulatory Class: Class II (two) Product Code: MHX Dated: May 8, 2009 Received: May 11, 2009

Dear Mr. Suchi:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food. Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA), You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

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Page 2 - Mr. Andreas Suchi

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply-with all the Act's requirements, including but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); medical device reporting (reporting of medical device-related adverse events) (21 CFR 803); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable; the electronic product radiation control provisions.(Sections 531-542 of the Act); 21 CFR 1000-1050.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please go to http://www.fda.gov/AboutFDA/CentersOffices/CDRH/CDRHOffices/ucm115809.htm for the Center for Devices and Radiological Health's (CDRH's) Office of Compliance. Also, please note the regulation entitled. "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to http://www.fda.gov/cdrh/mdr/ for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance.

You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (240) 276-3150 or at its Internet address http://www.fda.gov/cdrh/industry/support/index.html.

Sincerely yours,

Bram D. Zuckerman, M.D. Director Division of Cardiovascular Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

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Indications for Use

510(k) Number (if known): K091395

Philips IntelliVue MP5 Patient Monitor, Software Device Name: Revision G.1.

Indications for Use: Indicated for use by health care professionals whenever there is a need for monitoring the physiological parameters of patients. Intended for monitoring and recording of and to generate alarms for multiple physiological parameters of adults, pediatrics and neonates in hospital environments. The MP5 is also intended for use in transport situations within and outside of hospital environments.

Prescription Use (Part 21 CFR 801 Subpart D)

FR 801 Subpart D)

Over-The-Counter Use AND/OR (21 CFR 807 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE IF

NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Hollister for B Zuckerman

(Division Sign-Off) 6/5/09
Division of Cardiovascular Devices

510(k) Number K091395

§ 870.1025 Arrhythmia detector and alarm (including ST-segment measurement and alarm).

(a)
Identification. The arrhythmia detector and alarm device monitors an electrocardiogram and is designed to produce a visible or audible signal or alarm when atrial or ventricular arrhythmia, such as premature contraction or ventricular fibrillation, occurs.(b)
Classification. Class II (special controls). The guidance document entitled “Class II Special Controls Guidance Document: Arrhythmia Detector and Alarm” will serve as the special control. See § 870.1 for the availability of this guidance document.