K Number
K081377
Device Name
NUVASIVE SURGICAL MESH SYSTEM
Manufacturer
Date Cleared
2009-01-15

(244 days)

Product Code
Regulation Number
878.3300
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdparty
Intended Use
The Surgical Mesh System is intended to be implanted to reinforce soft tissue where weakness exists. The device is intended for one-time use.
Device Description
The original NuVasive Surgical Mesh System consists of a series of specialized shapes and sizes of mostly flat embroidered mesh and a radiographic marker. The meshes typically contain pre-formed reinforced holes to provide secure and easy to find suture or tissue anchor locations.
More Information

Not Found

No
The summary describes a physical surgical mesh and does not mention any software, algorithms, or data processing that would indicate the use of AI/ML.

Yes
The device is implanted to reinforce soft tissue where weakness exists, which is a therapeutic function.

No
The device is described as an implantable mesh for reinforcing soft tissue, with no mention of diagnostic capabilities, imaging, or analysis of medical conditions.

No

The device description clearly states it consists of "embroidered mesh and a radiographic marker," which are physical hardware components, not software.

No, this device is not an IVD (In Vitro Diagnostic).

Here's why:

  • Intended Use: The intended use is to be "implanted to reinforce soft tissue where weakness exists." This describes a device that is surgically placed within the body to provide structural support.
  • Device Description: The description details a "Surgical Mesh System" consisting of "embroidered mesh" and a "radiographic marker." This is consistent with a surgical implant.
  • Lack of IVD Characteristics: An IVD device is used in vitro (outside the body) to examine specimens (like blood, urine, or tissue) to provide information for diagnosis, monitoring, or screening. This device does not perform any such function.

The information provided clearly indicates this is a surgical implant, not an in vitro diagnostic device.

N/A

Intended Use / Indications for Use

The NuVasive Surgical Mesh System is intended to reinforce soft tissue where weakness exists. The device is intended for one-time use.

Product codes

FTL

Device Description

The original NuVasive Surgical Mesh System consists of a series of specialized shapes and sizes of mostly flat embroidered mesh and a radiographic marker. The meshes typically contain pre-formed reinforced holes to provide secure and easy to find suture or tissue anchor locations.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

soft tissue

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Not Found

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies

Not Applicable

Key Metrics

Not Found

Predicate Device(s)

K053215

Reference Device(s)

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information

Not Found

§ 878.3300 Surgical mesh.

(a)
Identification. Surgical mesh is a metallic or polymeric screen intended to be implanted to reinforce soft tissue or bone where weakness exists. Examples of surgical mesh are metallic and polymeric mesh for hernia repair, and acetabular and cement restrictor mesh used during orthopedic surgery.(b)
Classification. Class II.

0

VII. 510(k) Summary

In accordance with Title 21 of the Code of Federal Regulations, Part 807, and in particular §807.92, the following summary of information is provided:

A. Submitted by:

Laetitia Cousin Director of Regulatory Affairs and Quality Assurance NuVasive, Incorporated 4545 Towne Centre Court San Diego, California 92121 Telephone: (858) 909-1868 Fax: (858) 909-2068

B. Device Name

Trade or Proprietary Name: Common or Usual Name: Classification Name: Device Class: Classification: Product Code:

NuVasive Surgical Mesh System Surgical Mesh Surgical Mesh Class II $878.3300 FTL

C. Predicate Devices

The subject Surgical Mesh System is substantially equivalent to the Surgical Mesh System currently distributed commercially in the U.S. by NuVasive (K053215).

D. Device Description

The original NuVasive Surgical Mesh System consists of a series of specialized shapes and sizes of mostly flat embroidered mesh and a radiographic marker. The meshes typically contain pre-formed reinforced holes to provide secure and easy to find suture or tissue anchor locations.

E. Intended Use

The NuVasive Surgical Mesh System is intended to reinforce soft tissue where weakness exists. The device is intended for one-time use.

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Comparison to Predicate Devices F.

The subject device has indications for use identical to those of its predicate, and employs the same principles of operation.

G. Summary of Non-Clinical Tests

(Not Applicable).

H. Summary of Clinical Tests

(Not Applicable).

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DEPARTMENT OF HEALTH & HUMAN SERVICES

Image /page/2/Picture/1 description: The image shows the logo for the U.S. Department of Health & Human Services. The logo features a stylized eagle with three bars representing the agency's mission. The text "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" is arranged in a circular pattern around the eagle.

Public Health Service

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

NuVasive, Inc. % Ms. Laetitia Cousin Senior Director, Regulatory & Clinical Affairs and Ouality Assurance 7475 Lusk Boulevard San Diego, California 92121

Re: K081377

Trade/Device Name: NuVasive Surgical Mesh Regulation Number: 21 CFR 878.3300 Regulation Name: Surgical mesh Regulatory Class: II Product Code: FTL Dated: December 15, 2008 Received: December 16, 2008

Dear Ms. Cousin:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate for use stated in the encreated of the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The I ou may a controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act that I Drimas Intacted and regulations administered by other Federal agencies. You must or uny I vith all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set

JAN 1 5 2009

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Page 2 - Ms. Laetitia Cousin

forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

This letter will allow you to begin marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Center for Devices and Radiological Health's (CDRH's) Office of Compliance at (240) 276-0115. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding postmarket surveillance. please contact CDRH's Office of Surveillance and Biometric's (OSB's) Division of Postmarket Surveillance at (240) 276-3474. For questions regarding the reporting of device adverse events (Medical Device Reporting (MDR)), please contact the Division of Surveillance Systems at (240) 276-3464. You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (240) 276-3150 or at its Internet address http://www.fda.gov/cdrh/industry/support/index.html.

Sincerely yours,

Mark N Millman

Mark N. Melkerson Director Division of General, Restorative and Neurological Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

4

Indications for Use

510(k) Number (if known):

NuVasive Surgical Mesh Device Name:

Indications For Use:

The Surgical Mesh System is intended to be implanted to reinforce soft tissue where weakness exists. The device is intended for one-time use.

Prescription Use X (Part 21 CFR 801 Subpart D)

ﺔ ﺍﻟﺘﻲ ﺗﻌ

AND/OR

Over-The-Counter Use (21 CFR 807 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Offige of Device Evaluation (ODE)

(Division Sign-Off) Division of General, Restorative, and Neurological Devices

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510(k) Number K081377