K Number
K070364
Device Name
100KGY E-POLY MAXROM ACETABULAR LINERS
Manufacturer
Date Cleared
2007-05-03

(85 days)

Product Code
Regulation Number
888.3350
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
1) Non-inflammatory degenerative joint disease including osteoarthritis and avascular necrosis. 2) Rheumatoid arthritis. 3) Correction of functional deformity. 4) Treatment of non-union, femoral neck fracture, and trochanteric fractures of the proximal femur with head involvement, unmanageable using other techniques. 5) Revision of previously failed total hip arthroplasty. Cemented and Uncemented Applications
Device Description
Biomet Manufacturing Corp. is modifying the manufacturing process of ultrahigh molecular weight polyethylene (UHMWPE) used in the fabrication of polyethylene acetabular components. The modified manufacturing process results in a higher cross-linked polyethylene. The highly cross-linked UHMWPE is infused with medical grade Vitamin E.
More Information

Not Found

No
The summary describes a modification to the manufacturing process of a polyethylene component for hip arthroplasty. There is no mention of software, algorithms, or data processing that would indicate the use of AI or ML. The focus is on material science and manufacturing.

Yes
The device is a medical implant intended to treat various joint diseases and fractures, which falls under the definition of a therapeutic device.

No
The provided text describes a medical device, specifically a polyethylene acetabular component for hip arthroplasty, which is an implant used for treatment, not for diagnosing conditions. Its intended uses are corrections, treatments, and revisions of joint issues, not for identifying diseases.

No

The device description clearly states it is a modification to the manufacturing process of ultrahigh molecular weight polyethylene (UHMWPE) used in the fabrication of physical polyethylene acetabular components, which are hardware.

Based on the provided information, this device is not an IVD (In Vitro Diagnostic).

Here's why:

  • Intended Use: The intended use clearly describes a device for surgical implantation to treat various hip joint conditions. This is a therapeutic device, not a diagnostic one.
  • Device Description: The description details a modified polyethylene material for use in acetabular components (part of a hip implant). This is a physical implant, not a reagent, instrument, or system used to examine specimens from the human body.
  • Lack of IVD Characteristics: There is no mention of analyzing biological samples (blood, urine, tissue, etc.), detecting markers, or providing diagnostic information.

IVD devices are used to perform tests on specimens taken from the human body to provide information for diagnosis, monitoring, or screening. This device is a medical implant used for treatment.

N/A

Intended Use / Indications for Use

    1. Non-inflammatory degenerative joint disease including osteoarthritis and avascular necrosis.
    1. Rheumatoid arthritis.
    1. Correction of functional deformity.
    1. Treatment of non-union, femoral neck fracture, and trochanteric fractures of the proximal femur with head involvement, unmanageable using other techniques.
    1. Revision of previously failed total hip arthroplasty.

Cemented and Uncemented Applications

Product codes (comma separated list FDA assigned to the subject device)

JDI, LWJ, LPH, MAY

Device Description

Biomet Manufacturing Corp. is modifying the manufacturing process of ultrahigh molecular weight polyethylene (UHMWPE) used in the fabrication of polyethylene acetabular components. The modified manufacturing process results in a higher cross-linked polyethylene. The highly cross-linked UHMWPE is infused with medical grade Vitamin E.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

Hip

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Not Found

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies (study type, sample size, AUC, MRMC, standalone performance, key results)

Non-Clinical Testing: Non-clinical laboratory testing was performed to determine substantial equivalence. The results indicated that the device was functional within its intended use.
Clinical Testing: None provided as a basis for substantial equivalence.

Key Metrics (Sensitivity, Specificity, PPV, NPV, etc.)

Not Found

Predicate Device(s): If the device was cleared using the 510(k) pathway, identify the Predicate Device(s) K/DEN number used to claim substantial equivalence and list them here in a comma separated list exactly as they appear in the text. List the primary predicate first in the list.

K050327

Reference Device(s): Identify the Reference Device(s) K/DEN number and list them here in a comma separated list exactly as they appear in the text.

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information for the subject device only (e.g. presence / absence, what scope was granted / cleared under the PCCP, any restrictions, etc).

Not Found

§ 888.3350 Hip joint metal/polymer semi-constrained cemented prosthesis.

(a)
Identification. A hip joint metal/polymer semi-constrained cemented prosthesis is a device intended to be implanted to replace a hip joint. The device limits translation and rotation in one or more planes via the geometry of its articulating surfaces. It has no linkage across-the-joint. This generic type of device includes prostheses that have a femoral component made of alloys, such as cobalt-chromium-molybdenum, and an acetabular resurfacing component made of ultra-high molecular weight polyethylene and is limited to those prostheses intended for use with bone cement (§ 888.3027).(b)
Classification. Class II.

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K070364 page 1 of 2

Image /page/0/Picture/1 description: The image shows the word "BIOMET" in a bold, sans-serif font. The letters are outlined in black, with a white fill. The letters are all capitalized and evenly spaced. The "O" in the word is a perfect circle, while the other letters are more angular. The overall impression is one of strength and stability.

510(k) Summarv

Preparation Date: February 5, 2007

Applicant / Sponsor: Biomet Manufacturing Corp. MAY - 3 2007

Contact Person: Tracy Bickel Johnson, RAC

Proprietary Name: 100 kGy E-Poly™ MaxRom™ Acetabular Liners

Common Name: UHMWPE Liners

Classification Name(s):

  • LPH- prosthesis, hip, semi-constrained, metal/polymer, porous uncemented (888,3358); .
  • JDI- prosthesis, hip, semi-constrained, metal/polymer, cemented (888.3350); �
  • LWJ- prosthesis, hip, semi-constrained, metal/polymer, uncemented (888.3360); .
  • . MAY- prosthesis, hip, semi-constrained, metal/ceramic/polymer, cemented or non-porous cemented, osteophilic finish (888.3353)
  • LZO- prosthesis, hip, semi-constrained, metal/ceramic/polymer, cemented or non-porous. . uncemented (888.3353)

Legally Marketed Devices To Which Substantial Equivalence Is Claimed: K050327- E-

Poly™ (Vitamin E) Acetabular Liners

Device Description: Biomet Manufacturing Corp. is modifying the manufacturing process of ultrahigh molecular weight polyethylene (UHMWPE) used in the fabrication of polyethylene acetabular components. The modified manufacturing process results in a higher cross-linked polyethylene. The highly cross-linked UHMWPE is infused with medical grade Vitamin E.

Intended Une:

    1. Non-inflammatory degenerative ioint disease including osteoarthritis and avascular necrosis.
    1. Rheumatoid arthritis.
    1. Correction of functional deformity.
    1. Treatment of non-union, femoral neck fracture, and trochanteric fractures of the proximal femur with head involvement, unmanageable using other techniques.
    1. Revision of previously failed total hip arthroplasty.

Cemented and Uncemented Applications

Summary of Technologies: The intended use, indications, contraindications, and design specifications of the subject components remain identical to its predicate counterpart, with the exception of a manufacturing change. The raw material being utilized in the manufacture of both the subject and the predicate devices remains a ultra-high molecular weight polyethylene (UHMWPE) per ASTM F-648. The modifications to the manufacturing process of this polyethylene will be introduced in order to create a higher cross-linked polyethylene. The safety and effectiveness of this cross-linked polyethylene in acetabular applications are adequately supported by the substantial equivalence information, materials data, and testing results provided within this Premarket Notification.

Image /page/0/Picture/26 description: The image shows mailing and shipping addresses. The mailing address is P.O. Box 557, Monroe, WA 98272. The shipping address is 140 E. Main St. Monroe, WA 98272. There is also an office number listed as 360-794-6777.

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Page 2 of 2

510(K) Notification Biomet Manufacturing Corp. 100 kGy E-Poly™ MaxRom™ Acetabular Liners Page 2 of 2

Non-Clinical Testing: Non-clinical laboratory testing was performed to determine substantial equivalence. The results indicated that the device was functional within its intended use.

Clinical Testing: None provided as a basis for substantial equivalence.

All trademarks are property of Biomet, Inc.

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Public Health Service

Image /page/2/Picture/2 description: The image shows the logo for the U.S. Department of Health & Human Services. The logo features a stylized eagle with its wings spread, symbolizing protection and care. The words "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" are arranged in a circular pattern around the eagle.

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

Biomet Manufacturing Corp. % Ms. Tracy Bickel Johnson, RAC Manager, Regulatory Affairs P.O. Box 587 Warsaw, Indiana 46581-0587

MAY - 3 2007

Re: K070364

Trade/Device Name: 100kGy E-Poly™ MaxRom™ Acetabular Liners Regulation Number: 21 CFR 888.3350 Regulation Name: Hip joint metal/polymer semi-constrained cemented prosthesis Regulatory Class: II Product Code: JDI, LWJ, LPH, MAY Dated: April 3, 2007 Received: April 4, 2007

Dear Ms. Johnson:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

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Page 2 - Ms. Tracy Bickel Johnson, RAC

systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050. This letter will allow you to begin marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Office of Compliance at (240) 276-0120. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21 CFR Part 807.97). You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (240) 276-3150 or at its Internet address http://www.fda.gov/cdrl/industry/support/index.html.

Sincerely yours.

Barbara Buchum

Mark N. Melkerson Director Division of General. Restorative and Neurological Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

4

Indications for Use

Ko703 510(k) Number (if known):

1 1 1 1

Device Name: 100kGy E-Poly™ MaxRom™ Acetabular Components

Indications For Use:

    1. Non-inflammatory degenerative joint disease including osteoarthritis and avascular necrosis.
    1. Rheumatoid arthritis.
    1. Correction of functional deformity.
    1. Treatment of non-union, femoral neck fracture, and trochanteric fractures of the proximal femur with head involvement, unmanageable using other techniques.
    1. Revision of previously failed total hip arthroplasty.

Cemented and Uncemented Applications

Prescription Use _ YES (Part 21 CFR 801 Subpart D) AND/OR

Over-The-Counter Use NO (21 CFR 807 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Barbara Buchum

SIPPER Division of General, Restorative, and Neurological Devices

510(k) Number K070364

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