K Number
K063701
Device Name
TECO HOMOCYSTEINE ENZYMATIC ASSAY
Manufacturer
Date Cleared
2007-04-11

(119 days)

Product Code
Regulation Number
862.1377
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
Teco Enzymatic Homocysteine Assay is in vitro quantitative determination of total homocysteine in serum and plasma. Homocysteine measurements are used in the diagnostics and treatment of hyperhomocysteinemia.
Device Description
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More Information

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No
The summary describes a laboratory assay for measuring homocysteine, which is a chemical test and does not involve AI/ML. There are no mentions of AI, ML, image processing, or any other indicators of AI/ML technology.

No
The device is an in vitro diagnostic assay used for quantitative determination of homocysteine for diagnostic and treatment purposes, not for direct therapeutic intervention.

Yes
The "Intended Use / Indications for Use" section states that "Homocysteine measurements are used in the diagnostics and treatment of hyperhomocysteinemia," directly indicating its diagnostic purpose.

No

The device is an in vitro diagnostic assay, which is a chemical or biological test performed on samples from the human body. This inherently involves reagents and laboratory equipment, not just software.

Yes, based on the provided information, the Teco Enzymatic Homocysteine Assay is an IVD (In Vitro Diagnostic) device.

Here's why:

  • Intended Use: The intended use explicitly states it is for the "in vitro quantitative determination of total homocysteine in serum and plasma." This means the test is performed outside of the body (in vitro) on biological samples (serum and plasma) to measure a specific substance (homocysteine).
  • Purpose: The intended use also states that these measurements are "used in the diagnostics and treatment of hyperhomocysteinemia." This indicates the device is used to aid in the diagnosis and management of a medical condition.

These are key characteristics of an IVD device.

N/A

Intended Use / Indications for Use

Teco Enzymatic Homocysteine Assay is in vitro quantitative determination of total homocysteine in serum and plasma. Homocysteine measurements are used in the diagnostics and treatment of hyperhomocysteinemia.

Product codes

LPS

Device Description

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Mentions image processing

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Mentions AI, DNN, or ML

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Input Imaging Modality

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Anatomical Site

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Indicated Patient Age Range

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Intended User / Care Setting

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Description of the training set, sample size, data source, and annotation protocol

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Description of the test set, sample size, data source, and annotation protocol

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Summary of Performance Studies

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Key Metrics

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Predicate Device(s)

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Reference Device(s)

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Predetermined Change Control Plan (PCCP) - All Relevant Information

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§ 862.1377 Urinary homocystine (nonquantitative) test system.

(a)
Identification. A urinary homocystine (nonquantitative) test system is a device intended to identify homocystine (an analogue of the amino acid cystine) in urine. The identification of urinary homocystine is used in the diagnosis and treatment of homocystinuria (homosystine in urine), a heritable metabolic disorder which may cause mental retardation.(b)
Classification. Class II.

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DEPARTMENT OF HEALTH & HUMAN SERVICES

Image /page/0/Picture/1 description: The image shows the logo for the U.S. Department of Health & Human Services. The logo features a stylized depiction of an eagle or bird with outstretched wings. The words "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" are arranged in a circular pattern around the bird.

Food and Drug Administration 2098 Gaither Road Rockville MD 20850

APR 1 1 2007

Teco Diagnostics 1268 North Lakeview Avenue Anaheim, CA 92807 ATTN: Jian Vaeches

Re: K063701 Trade/Device Name: Teco Enzymatic Homocysteine Assay Regulation Number: 21 CFR 862.1377 Regulation Name: Urinary homocystine (non-quantitative) test system. Regulatory Class: Class II Product Codes: LPS Dated: February 21, 2007 Received: February 21, 2007

Dear Ms. Vaeches:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food. Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in Title 21, Code of Federal Regulations (CFR), Parts 800 to 895. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Parts 801 and 809); and good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820).

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This letter will allow you to begin marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific information about the application of labeling requirements to your device, or questions on the promotion and advertising of your device, please contact the Office of In Vitro Diagnostic Device Evaluation and Safety at (240) 276-0490. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (240) 276-3150 or at its Internet address at http://www.fda.gov/cdrh/industry/support/index.html.

Sincerely yours,

Jean M. Cooper, M.S., D.V.M.

Jean M. Cooper, M.S., D.V.M. Director Division of Chemistry and Toxicology Office of In Vitro Diagnostic Device Evaluation and Safety Center for Devices and Radiological Health

Enclosure

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Indications for Use

K063701 510(k) Number (if known):

Device Name: Teco Enzymatic Homocysteine Assay

Indications for Use:

Teco Enzymatic Homocysteine Assay is in vitro quantitative determination of total homocysteine in serum and plasma. Homocysteine measurements are used in the diagnostics and treatment of hyperhomocysteinemia.

Prescription Use V

AND/OR

Over-The-Counter Use

(Part 21 CFR 801.109) (PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of In Vitro Diagnostic Devices (OIVD)

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Carol C. Benson

Division Sign-Off

Office of In Vitro Diagnostic Device Evaluation and Safety

K063701