K Number
K062490
Date Cleared
2006-10-27

(63 days)

Product Code
Regulation Number
892.2050
Reference & Predicate Devices
Predicate For
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

Visage PACS/CS: is a system for distributing, viewing, and processing medical images and reports within and outside health care environments. It is to be used only by trained and instructed health care professionals. Visage PACS consists of the following components:

Visage PACS Storage: Visage PACS Storage offers an archiving option for long-term storage of image data

Visage PACS Web: Data that are stored on the Visage PACS Storage server can be accessed simultaneously by multiple web-based viewing stations within or outside a healthcare enterprise through web clients.

Visage CS: Visage CS is a client server system that uses thin client technology for distribution of 3D image data generated from image data of state-of-the-art scanning modalities

Integration with other hospital information systems (HIS, RIS, CIS) is provided via special interfaces.

Device Description

Visage PACS is a system to distribute, view, and process medical images and reports within and outside of health care environments. It consists of the following components:

  • Visage PACS Storage -
  • Visage PACS Web -
  • Visage CS -

Visage PACS Storage: A server receives image data in DICOM format via the hospital network. This provides universal connections to archives, modalities and workstations. Visage PACS Storage offers an archiving option for long-term storage of image data.

Visage PACS Web: Data that are stored on the Visage PACS Storage server can be accessed simultaneously by multiple web-based viewing stations within a healthcare enterprise or from elsewhere outside through web clients. The image data transfer is done in DICOM format via the Intranet or the Internet. Images can be viewed directly within a web browser (Internet Explorer). The system offers simple functions for image manipulation and measurements. Reports can be viewed together with the images on one page.

Visage CS: Visage CS is a client server system that uses thin client technology for distribution of 3D image data generated from image data of state-of-the-art scanning modalities. The thin client viewer allows to view and process 3D image data. No DICOM data is transferred to the client. Instead of image data, a stream of compressed screen content information is transmitted during interaction.

AI/ML Overview

The provided document (K062496, VISAGE PACS/CS Premarket Submission Summary dated August 24, 2006) describes a Picture Archiving and Communications System (PACS) and does not contain information about acceptance criteria or a study proving the device meets those criteria in the context of clinical performance or diagnostic accuracy.

Instead, the submission focuses on:

  • Substantial Equivalence: It asserts that the VISAGE PACS/CS is substantially equivalent to a predicate device (TeraRecon AquariusNet Server/Thin client, K012086). The "Substantial Equivalence Comparison Chart" (pages 5-6) details similarities in functionality, hardware/software requirements, and features between the Visage PACS/CS, the predicate device, and a previous version of the submitter's product (RADIN 3.0). This comparison serves as the primary and only "study" presented to demonstrate equivalency and fitness for purpose.
  • Software Development Process and Risk Analysis: It states that the software was "designed, developed, tested and validated according to written procedures" and that a "risk analysis has been performed to identify all potential safety or health hazards."

Therefore, it is not possible to fill out the requested table and details because the submission does not include elements such as:

  1. Specific Acceptance Criteria related to diagnostic performance (e.g., sensitivity, specificity, AUC).
  2. Device Performance Metrics against such criteria.
  3. Details of a test set (sample size, data provenance), ground truth establishment (number/qualifications of experts, adjudication methods, type of ground truth), or training set details.
  4. Multi-Reader Multi-Case (MRMC) comparative effectiveness studies or standalone algorithm performance studies.

The document aims to establish substantial equivalence primarily through a feature-by-feature comparison with a legally marketed predicate device, rather than through a direct clinical performance study with defined acceptance criteria and statistical analysis.

No study proving the device meets acceptance criteria regarding diagnostic performance or clinical effectiveness is described in this document. The safety and effectiveness claims are based on the device's substantial equivalence to a predicate device and adherence to quality system regulations and a risk management plan.

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K06 2496

Premarket Submission VISAGE PACS/CS Summary

24 Aug 2006

A.1 510(k) Summary of Safety and Effectiveness

A.1.1 Company Identification

Mercury Computer Systems, Inc. 199 Riverneck Road Chelmsford, MA 01824-2820 United States of America

A.1.2 Official Correspondent

Richard Glasheen 199 Riverneck Road Chelmsford, MA 01824-2820 United States of America Tel.: 978-967-1843 Fax: 978-256-0588 E-Mail: rglashee@mc.com

A.1.3 Date of Submission

24 Aug 2006

A.1.4 Device Name

Trade name:VISAGE PACS/CS
Release Version:4.1
Common name:VISAGE PACS/CS
Classification Name:Picture Archiving and Communications System
Reference:per 21 CFR 892.2050
Class:II
Review Panel:Radiology
Product Classification:90 LLZ, Picture Archiving and Communications System

Guidance for the submission of premarket notifications for Guidance document: medical image management systems (issued on july 27, 2000)

A.1.5 Substantial Equivalence

The Visage PACS/CS Software is substantially equivalent, in the opinion of Mercury Computer Systems Inc., to TeraRecon AquariusNet Server/Thin client (K012086, Class II).

A.1.6 Device Description

Visage PACS is a system to distribute, view, and process medical images and reports within and outside of health care environments. It consists of the following components:

  • Visage PACS Storage -
  • Visage PACS Web -
  • Visage CS -

Visage PACS Storage

OCT 2 7 2006

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A server receives image data in DICOM format via the hospital network. This provides universal connections to archives, modalities and workstations. The modalities that are supported by Visage PACS Storage are listed in the DICOM Conformance Statement.

Visage PACS Storage offers an archiving option for long-term storage of image data. Only the data consistency on archive media is guaranteed, the system provider has to take own appropriate means (e.g. redundancy) for safety against data loss caused by media destruction. Without the archiving option, the Visage PACS system features no components for long-term data archiving. Additional archiving on film or in digital form is therefore necessary.

Visage PACS Web

Data that are stored on the Visage PACS Storage server can be accessed simultaneously by multiple web-based viewing stations within a healthcare enterprise or from elsewhere outside through web clients.

The image data transfer is done in DICOM format via the Intranet or the Internet, for example to stations located in a doctor's office, throughout hospitals or a physician's home. Strong data encryption is provided (SSL) to ensure a secure data transfer. Images can be viewed directly within a web browser (Internet Explorer). The system offers simple functions for image manipulation and measurements.

Reports can be viewed together with the images on one page.

Visage CS

Visage CS is a client server system that uses thin client technology for distribution of 3D image data generated from image data of state-of-the-art scanning modalities. The thin client viewer allows to view and process 3D image data. No DICOM data is transferred to the client. It remains on the 3D Application Server at any time, ensuring safe and consistent access to large 3D data throughout the hospital enerprise. Instead of image data, a stream of compressed screen content information is transmitted during interaction. If Visage CS is used in un-secure networks (e.g. WAN) third party VPN (Virtual Private Network) solutions have to be used to secure the data transfer between the Visage Server and the client machines.

A.1.7 Intended Use

Visage PACS is a system for distributing, viewing, and processing medical images and reports within and outside health care environments. It is to be used only by trained and instructed health care professionals. Visage PACS consists of the following components:

  • Visage PACS Storage

  • । Visage PACS Web -

    • Visage CS

Integration with other hospital information systems (HIS, RIS, CIS) is provided via special interfaces.

Visage PACS Storage

A server receives image data in DICOM format via the hospital network. This provides universal connections to archives, modalities, and workstations. The modalities that are supported by Visage PACS Storage are listed in the DICOM Conformance Statement.

Visage PACS Storage offers an archiving option for long-term storage of image data. The system guarantees the consistency of the data stored on archiving media but does not prevent data loss caused by media destruction.

Visage PACS Web

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Data that are stored on the Visage PACS Storage server can be accessed simultaneously by multiple web-based viewing stations within or outside a healthcare enterprise through web clients.

The image data are transferred in DICOM format via the Intranet or the Internet, for example to stations located in a doctor's office, throughout hospitals or a physician's home. Strong data encryption is provided (SSL) to ensure secure data transfer. Images can be viewed directly within a web browser (Internet Explorer). The system offers simple functions for image manipulation and measurements. Reports can be viewed together with the images on one page.

Visage CS

Visage CS is a client server system that uses thin client technology for distribution of 3D image data generated from image data of state-of-the-art scanning modalities.

The thin client viewer allows viewing and processing of 3D image data. No DICOM data is transferred to the client. It remains on the 3D Application Server at all times, ensuring safe and consistent access to large volumes of 3D data throughout the hospital enterprise. Instead of image data, a stream of compressed screen content information is transmitted during interaction.

If Visage CS is used in insecure networks (e.g. WAN), third party VPN (Virtual Private Network) solutions have to be used to secure data transfer between the Visage Server and the client machines.

Important Usage Notes

Visage PACS can support physicians and/or their medical staff in providing their own diagnosis for medical cases. The final decision regarding diagnoses, however, resides with the doctors and/or their medical staff in their own area of responsibility.

Although the web and thin client technologies allow the software to be run on a variety of hardware platforms, for diagnostic purposes the user must make sure that the display hardware used for reading the images complies with state-of-the-art diagnostic requirements and currently valid laws.

Mammographic images compressed by a lossy method and digitized film screen images must not be reviewed for primary image interpretations.

The computers hosting the server-side software of Visage PACS/CS must be operated in a server room ensuring the appropriate operating and environmental conditions and access control.

A.1.8 Software Development

Mercury Computer Systems, Inc. certifies that the VISAGE PACS/CS software is designed, developed, tested and validated according to written procedures. These procedures identify individuals within the organization responsible for developing and approving product specifications, coding and testing, validation testing and field maintenance. All employees receive the appropriate quality system training.

The Mercury Computer Systems, Inc. Quality System is in compliance with the following voluntary and mandatory standards and regulations:

Standard/RegulationTitle
21 CFR 820Quality Systems Regulation
ISO 9001:2000Quality Management Systems - Requirements
ISO 13485:2003Quality Systems - Medical Devices - Particular requirementsfor the application of ISO 9001

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93/42/EECMedical Device Directive
and and the beginner for the first for the first of the first and the first and the first and the first and the first and the first and the first and the first and the first(IEC) 60601-1-4------------------------------------------------------------------------------------------------------------------------------------------------------------------------------International Electrotechnical Commission

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A.1.9 Substantial Equivalence Comparison Chart

Annotation:

Our Visage product line consists of 2D Web based PACS software and a separate 3D Visage Server and Thin Clients to give the end user a complete 2D/3D PACS experience. The software backend of the Visage product is based on the RADIN 3.0 product that received 510(k) approval (K043483) from the FDA In 2004. RADIN 3.1 was granted 510(k) approval to Sohard AG which was acquired by Mercury Computer Systems, Inc. in 2005.

TeraRecon unites 2D/3D into one System, AquariusNet Server and Thin Clients, but has no PACS functionality. TeraRecon also provides the same Thin Client software suite on a stand- alone workstation, Aquarius Blue.

Image /page/4/Figure/7 description: This image shows a diagram of a medical imaging system. The diagram includes components such as an Aquarius Workstation, AquariusNET, Personal Digital Light Box, and Thin Client. The diagram also shows connections between the different components, indicating how they are integrated within the system. The text in the image includes labels for the different components, as well as the phrases "Powered by VolumePro" and "Powered by TeraRecon F-1".

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Substantial Equivalence comparison Chart
------------------------------------------------
ProductVisage PACS/CS4.1AquariusNetServer/Thin clientRADIN 3.0
Company NameMercury ComputerSystems, Inc.TeraRecon, Inc.Mercury ComputerSystems, Inc.Formally SoHardAG
510 (k) numberTBDK012086K043483
General
NetworkingTCP/IPYesTCP/IP
Image Acquisition/CommunicationDICOM CompliantYesDICOM Compliant
Image file formatsDICOM 3.0YesDICOM 3.0
Imaging modalitiesMulti ModalityYesMulti Modality
PlatformPCPCPC
Operating SystemWindowsWindowsWindows
Standard Microsoft TechnologyYesYesYes
DICOM 3.0 CompliantYesYesYes
Patient DemographicsYesYesYes
DICOM Storage SCPYesYesYes
DICOM Storage SCUYesYesYes
DICOM Query/Retrieve SCU/SCPYesYesYes
DICOM Storage CommitmentYesYesNo
HIPAA compliantYesYesYes
Secure data transmissionSSL encryption,VPN encryptionVPN, encryptionYes
User authenticationYesYesYes
User AccountYesYesYes
User groupsYesYesYes
User LevelsYesNoYes
Visage PACS/CS Online
Scalability
Concurrent user modelYesYesYes
Data Storage
Format
Original FormatYesYesYes
JPEG LosslessYesYesYes
JPEG LossyYes (5-100%)YesYes (5-100%)
WaveletYes (5-100%)Yes (0-100%)Yes (5-100%)
Storage SpaceManagement
Intelligent storagemanagementYesYesYes
Data Storage
Device
RAID, SAN, NAS250GB to severalTBRAID, SAN, NAS
DICOM Network
DICOM Confor-manceDICOM 3.0DICOM 3.0DICOM 3.0
Hardware and Soft-ware Requirementsfor server
HardwareSoftwarePC 2x Pentium III1,4 GHz or PC 1xPentium IV 3GHz(Hyperthreading),>= 1GB RAM2x 60 GB HarddiskSCSI or SATAWindows2003WorkstationLatestDell Power SolutionVolumePro(Ter-Graphicsrarecon)Board,Pentium4Intelprocessor, 2.0 GHzor faster512MB of SDRAMsystem memory120GB HardDiskDrive storageWindowsNT4.0.PC111,Pentiummin 500MHz512 MB RAM20 GB HarddiskWindows2003
ServerInternet Explorer 6Windows 2000, Win2003ServerInternet Explorer 6
Workflow Features
DICOM report inter-faceYesYesYes
File based reportinterfaceYesYesYes
URL interface forOEM integrationYesYesYes
Creation of patientmedia (DVD) ac-cording to DICOMstandardYesYesYes
Visage PACS/CS3D Server
ScalabilityYesYesYes
Data Storage For-mat
Volume DataYesYes
Hardware and Soft-ware Requirements
HardwareMinimum 2x dualcore Opteron, 8GBRAM, graphicadapter 2xFX4500, 1x 160GBHarddiskWorkstation LatestDell Power SolutionVolumePro (Terare-con) GraphicsBoard,Pentium 4 Intelprocessor, 2.0 GHzor faster512MB of SDRAMsystem memory120GB Hard DiskDrive storagePentium 2 GHz512 MB RAM50-100 GB Hard-disk
SoftwareSuSe Linux version10.0Windows NT 4.0,Windows 2000, Win2003Windows 2003ServerInternet Explorer 6
Workflow Features
URL interface forOEM integrationYesYes, added capabil-ityYes
Visage PACS/CSArchive
Storage Modules
Harddisk RAIDYesYes
SAN systemsYesYes
NAS systemsYesYes
Data Security
Data verification onmediaYesNoYes
Manipulation detec-tionYesNoYes
Database consis-tency checkYesNoYes
Archive typePACSPACS or UNCmount point storagePACS
Hardware and Soft-ware Requirements
HardwarePentium 2 GHz512 MB RAM50-100 GB Hard-diskStandard Dell HighPerformance Prod-uct
SoftwareWindows 2003ServerInternet Explorer 6Windows NT 4.0,Windows 2000
Visage PACS/CSWEB Client
Key Features
Full DICOM imageson clientsYesYesNo
No Software Installa-tion, just InternetExplorer neededYesNo, thin client alsofor 2D part. Alsohas activeX clientthat can run withinIE and does notrequire clientdownload.Yes
Supported Modali-tiesCR, CT, DR, DS,DX, ES, GM, IO,MG, MR, NM, PT,OT, RF, RT, US,XA, XCCR,CT,MR,DR, US,PT, NM, DX, OT,RF, SC, XF, XACR, CT, DR, DS,DX, ES, GM, IO,MG, MR, NM, PT,OT, RF, RT, US,XA, XC
Supported ImageTypes
Greyscale, Color,MultiframeYesYesYes
Image ManipulationFunctions
ZoomYesYesYes
Quick ZoomYesYesYes
Magnifying glassYesNoYes
PanYesYesYes
Window levelingYesYesYes
Edge enhancementYesYesYes
Grayscale inversionYesYesYes
Rotating, flippingYesYesYes
MPR, MIPYesYesNo
MeasurementFunctions
DistanceYesYesYes
AngulationYesYesYes
AreaYesYesYes
Greyscale densitiy(probe)YesYesYes
Manual distancecalibrationYesYesYes
Cine ModeYesYesYes
Workflow features
Database FiltersYesYesYes
DICOMquery/retrieve fromarchives and work-stationsYesYesYes
Change user andgroup assignment ofpatientsYesYesYes
Multiple series load-ingYesYesYes
Preloading of im-ages to the clientYesNo - Not neededYes
Study availabilitystatusYesNo - if study is inthe worklist it isavailable. Loadtime from PACSarchive for 500 im-age CT dataset is<30 secsYes
Display of imagestogether with reportsYesYesYes
Creation and Modifi-cation of advancedreport annotationsYesYesYes
Easy integration withRIS/HIS systemsYesNoYes
Windows Copy andPrint FunctionsYesYesYes
DICOM printYesYesYes
Hardware and Soft-ware Requirements
HardwareMinimum Pentium III 500 MHz, 256 MB RAM, Standard PC graphics card 1024 * 768 true color, 2 GB Harddisk space, Network or telephone adapter300MHz Pentium® MMX, Standard 2D video graphics adapterPentium III 500 MHz, (Pentium IV 2 GHz recommended) 128 MB RAM (512 MB recommended) Standard PC graphics card, 1024 * 768 minimum resolution 2 GB Harddisk Network or telephone adapter
SoftwareMicrosoft Windows 2000 or XP Internet Explorer 6.0Windows 2000, NT, XP, or 98, Win 2003Microsoft Windows 2000 or XP Internet Explorer 5.5 or 6.0
Additional Features
Multiple Monitor SupportYesYesYes
Support for High Resolution MonitorsYesYes - No upper limit
Key FeaturesThin Client Not supported by RADIN
Supported ModalitiesCT, MR, PTCT, MR, PT, US, CR, DR, XA, NM, FLCT, MR, PT
Supported Image Types
GreyscaleYesYes
Image Manipulation Functions
ZoomYesYes
PanYesYes
Window levelingYesYes
Grayscale inversionYesYes
3D Volume NavigationYesYes
MPR, MIPYesYes
Measurement Functions
Distance
AngulationYesYesYes
AreaYesYesYes
Greyscale density(probe)YesYesYes
AnnotationsYesYesYes
Cine ModeYesYesYes
Workflow features
Database FiltersYesYes
DICOMquery/retrieve fromarchives and work-stationsYesYes
Multiple series load-ingYesYes
Easy integration withRIS/HIS systemsYesNo
Windows Copy andPrint FunctionsYesYes
result image exportYesYes
predefined protocolsand layouts for eachmodality and screensetupYesYes
User defined colorand 3D renderingschemesYesYes
Large Vessel Ap-plication
Freehand croppingand patient tableremovalYesYes
Curved reformattingYesYes
Semi-automaticlarge vessel seg-mentationYesYes
Quick navigationalong vesselsYesYes
Easy measurementof vessel cross sec-tionYesYes
PET/CT and NMApplication
Optimized for com-bined PET/CT mo-dalitiesYesYes
Predefined PET/CTprotocols and NMcolormapsYesYes
MPR and VRT fu-sion display, inverseMIPYesYes
Manual correction ofspatial registrationYesYes
Hardware and Soft-ware Requirements
HardwareThe thin client runson any x86 com-patible processorsupporting theMMX instructionset (e.g. Intel Pen-tium I MMX, AMDK6, or higher).300MHz Pentium®MMX ,Standard 2Dvideo graphicsadapter
SoftwareMicrosoft Windows2000 or XPWindows 98, NT,2000, XP, Win 2003
Advanced 3D Visu-alization Features
3D and 4D Naviga-tionYesYes
Orthogonal and per-spective viewingprojectionYesYes
VRT, SVRTYesYes
Cropping and clip-pingYesYes
Additional Features
Mulitple MonitorSupportYesYes

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Mercury Computer Systems, Inc.

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Premarket Submission

VISAGE PACS/CS Summary

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Premarket Submission

VISAGE PACS/CS Summary

24 Aug 2006

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Premarket Submission

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Hardware andSoftwareRequirementsPremarket SubmissionVISAGE PACS/CS SummaryMercury Computer Systems, Inc.199 Riverneck RoadChelmsford, MA 01824-2820United States of America
HardwarePentium 2 GHz512 MB RAM50-100 GB Harddisk24 Aug 2006Standard Dell HighPerformance Product
SoftwareWindows 2003 ServerInternet Explorer 6Windows NT 4.0,Windows 2000
Visage PACS/CSWEB ClientAquariusNetServer/Thin cli-entRADIN 3.0
Key Features
Full DICOM imageson clientsYesYes
No SoftwareInstallation, justInternet ExplorerneededYesNo, thin client also for2D part. Also hasactiveX client that canrun within IE and doesnot require clientdownload.Yes
Supported ModalitiesCR, CT, DR, DS, DX,ES, GM, IO, MG, MR,NM, PT, OT, RF, RT,US, XA, XCCR,CT,MR,DR, US,PT, NM, DX, OT, RF,SC, XF, XACR, CT, DR, DS, DX,ES, GM, IO, MG, MR,NM, PT, OT, RF, RT,US, XA, XC
Supported ImageTypes
Greyscale, Color,MultiframeYesYesYes
Image ManipulationFunctions
ZoomYesYesYes
Quick ZoomYesYesYes
Magnifying glassYesNoYes
PanYesYesYes
Window levelingYesYesYes
Edge enhancementYesYesYes
Grayscale inversionYesYesYes
Rotating, flippingYesYesYes
MPR, MIPYesYesNo
MeasurementFunctions
DistanceYesYesYes
AngulationYesYesYes
AreaYesYesYes
Greyscale density(probe)YesYesYes
Manual distance cali-brationYesYesYes
Cine ModeYesYesYes
Workflow features
Database FiltersYesYesYes

:

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A.1.10Safety and Effectiveness

General Safety and Effectiveness Concerns A.1.10.1

VISAGE PACS/CS is a medical device that is to be used by trained health care professionals who are responsible for the correct and accurate use of medical images e.g. as a means for providing diagnosis.

The device labeling contains instructions for use and the intended use/indications for use. Warnings, faults etc are explained in the users manual.

Data that are compressed are properly identified in the image information as being compressed as specified by the DICOM standard. This compression identification remains with the image for the entire life of the image. The correctness of the compression 3d party software is validated by the testing routine for 3d party components during the system/integration test.

A.1.10.2 Validation and Effectiveness

The VISAGE PACS/CS risk analysis has been performed to identify all potential safety or health hazards during system operation. The hazards are controlled by a risk management plan, including hazard analysis, verification and validation tests (according to our software development process) and evaluations by hospitals.

According to our risk analysis and risk management there are no software components within the VISAGE PACS/CS Software, whose failure or latent design flaw would be expected to result in death or injury to a patient.

Requirement tracing covering specification, design, implementation and verification/validation ensures the fulfillment of all phase requirements, EHR and DMR ensures direct access to all documents.

Integration test plan defines full testing at integration and system testing level. According to this test plan integration and system testing including full testing of hazard mitigation has been performed.

Decision Reviews at the conclusion of each software development phase ensure the fulfillment of the phase results and the validity of the Intended Use and the risk analysis. Testing is an integral part of our Software Design Process.

A.1.10.3 Substantial Equivalence

Any differences between the VISAGE PACS/CS Software and the substantially equivalent device have no significant influence on safety and effectiveness.

A.1.10.4 Technological characteristics

VISAGE PACS/CS is a stand-alone software package used on general purpose hardware, as long as the minimum hardware requirements specified in the manuals are met.

It is based upon standard Microsoft™ technology,

The device does not contact the patient, nor does it control any life sustaining devices.

A physician, providing ample opportunity for competent human intervention interprets images and information delivered by VISAGE PACS/CS.

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A.1.10.5 Conclusion

We believe that the 510(k) premarket notification contains adequate information and data to enable FDA to determine substantial equivalence to the predicate device.

VISAGE PACS/CS has been and will be manufactured in accordance with the mandatory and voluntary standards listed in this submission.

This submission contains the result of the hazard analysis and all potential hazards have been classified as minor.

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Image /page/16/Picture/1 description: The image is a circular seal or logo. It features the emblem of the U.S. Department of Health & Human Services (HHS). The emblem consists of a stylized caduceus-like symbol with three lines extending from a central point, resembling a bird in flight. The text "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" is arranged around the perimeter of the circle.

Food and Drug Administration 9200 Corporate Blvd. Rockville MD 20850

OCT 2 7 2006

Mr. Richard Glasheen Official Correspondent Mercury Computer Systems, Inc. 199 Riverneck Road CHELMSFORD MA 01824-2820

Re: K062490

Trade/Device Name: VISAGE PACS/CS Regulation Number: 21 CFR 892.2050 Regulation Name: Picture archiving and communications system Regulatory Class: II Product Code: LLZ Dated: August 24, 2006 Received: August 31, 2006

Dear Mr. Glasheen:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (Premarket Approval), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Image /page/16/Picture/10 description: The image is a black and white circular logo. The logo contains the text "1906-2006" at the top, "PA" in the center, and "Centennial" at the bottom. There are three stars below the word "Centennial". The logo appears to be a commemorative emblem for a centennial celebration.

Protecting and Promoting Public Health

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Page 2 -

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

This letter will allow you to begin marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Office of Compliance at one of the following numbers, based on the regulation number at the top of this letter:

21 CFR 876.xxx(Gastroenterology/Renal/Urology)240-276-0115
21 CFR 884.xxx(Obstetrics/Gynecology)240-276-0115
21 CFR 894.xxx(Radiology)240-276-0120
Other240-276-0100

Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (240) 276-3150

or at its Internet address http://www.fda.gov/cdrl/industry/support/index.html.

Sincerely yours,

Nancy C. Hogdon

Nancy C. B rogdon Director, Division of Reproductive, Abdominal, and Radiological Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

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Section D: Statement of Indications for Use

Amended Version 1: Indication for Use Amendment Date: 17 Oct 2006

510(k) Number: K062490 Device Name: VISAGE PACS/CS Indications for Use:

Visage PACS/CS: is a system for distributing, viewing, and processing medical images and reports within and outside health care environments. It is to be used only by trained and instructed health care professionals. Visage PACS consists of the following components:

Visage PACS Storage: Visage PACS Storage offers an archiving option for long-term storage of image data

Visage PACS Web: Data that are stored on the Visage PACS Storage server can be accessed simultaneously by multiple web-based viewing stations within or outside a healthcare enterprise through web clients.

Visage CS: Visage CS is a client server system that uses thin client technology for distribution of 3D image data generated from image data of state-of-the-art scanning modalities

Integration with other hospital information systems (HIS, RIS, CIS) is provided via special interfaces.

Prescription Use

David h. Sageman

(Division Sign-Off) Division of Reproductive, Abdominal, and Radiological Devices 510(k) Number ________________________________________________________________________________________________________________________________________________________________

§ 892.2050 Medical image management and processing system.

(a)
Identification. A medical image management and processing system is a device that provides one or more capabilities relating to the review and digital processing of medical images for the purposes of interpretation by a trained practitioner of disease detection, diagnosis, or patient management. The software components may provide advanced or complex image processing functions for image manipulation, enhancement, or quantification that are intended for use in the interpretation and analysis of medical images. Advanced image manipulation functions may include image segmentation, multimodality image registration, or 3D visualization. Complex quantitative functions may include semi-automated measurements or time-series measurements.(b)
Classification. Class II (special controls; voluntary standards—Digital Imaging and Communications in Medicine (DICOM) Std., Joint Photographic Experts Group (JPEG) Std., Society of Motion Picture and Television Engineers (SMPTE) Test Pattern).