K Number
K061443
Date Cleared
2006-06-23

(30 days)

Product Code
Regulation Number
882.1900
Reference & Predicate Devices
Predicate For
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

The intended use of the Smart USBLite device system is for the recording of auditory evoked potential, otoacoustic emissions, & auditory steady-state evoked potential data. The product is intended to be used as a diagnostic aid in auditory and hearing related disorders, as an objective measure of cochlear function, and as an adjunctive tool in the estimation of behavioral hearing thresholds on patients of all ages.

Device Description

Smart USBLite is an auditory evoked potential and otoacoustic emission system that is capable of recording and measuring auditory evoked potential, otoacoustic emission, and auditory steady-state evoked potential data. The Smart USBLite system combines the following FDA 510(k) previously cleared devices into a repackaged, smaller-sized, single integrated unit: SmartEP (K904926), SmartScreener (K925648), SmartOAE (K964426), SmartTrOAE (K023859), SmartEP-ASSR (K031051), and Opti-Amp DC-Powered (K052060).

AI/ML Overview

The Smart USBLite is an auditory evoked potential and otoacoustic emission system that records and measures auditory evoked potential, otoacoustic emission, and auditory steady-state evoked potential data. It combines several previously cleared predicate devices into a repackaged, smaller-sized, single integrated unit. The device is intended as a diagnostic aid for auditory and hearing-related disorders, an objective measure of cochlear function, and an adjunctive tool for estimating behavioral hearing thresholds across all patient ages.

The study presented does not include specific acceptance criteria with quantifiable metrics for performance, nor does it detail a standalone study proving the device meets particular performance thresholds. Instead, the submission relies on demonstrating substantial equivalence to predicate devices through a comparison of technological characteristics and specifications. The "acceptance criteria" appear to be satisfied by the device's adherence to the same intended use, methodologies, and performance specifications as the established predicate devices, coupled with certification for electrical safety and electromagnetic compatibility.

Here's a breakdown of the requested information based on the provided text:

1. Table of Acceptance Criteria and Reported Device Performance

As mentioned, explicit quantifiable acceptance criteria with corresponding reported performance metrics are not provided in the document. The submission focuses on claiming substantial equivalence to predicate devices. The "performance" is implicitly accepted if the new device's specifications are the same as the predicate devices or within acceptable limits for a repackaged unit.

However, the closest representation of "acceptance criteria" and "reported device performance" can be extrapolated from the "Specifications" table by comparing the "Predicate Devices" column to the "Device Under Current 510(k) Review (Smart USBLite)" column. The acceptance criterion for each parameter is implicitly the specification of the predicate device, and the reported performance is the "Same" or adjusted value for the Smart USBLite.

ParameterAcceptance Criteria (Predicate Device Specification)Reported Device Performance (Smart USBLite)
Intended UseStimulate, record, & process auditory evoked potentials, auditory evoked potential screening, elicitation and measurement of otoacoustic emissions, and auditory steady-state evoked potentials. Diagnostic aid for auditory and hearing related disorders, objective measure of cochlear function, adjunctive tool for estimation of behavioral hearing thresholds.Same
Indications for UseRecording & analysis of physiological data for diagnosis of auditory/hearing-related disorders; determination of cochlear function.Same
Target PopulationAll AgesSame
DesignExternal box housing circuitry connected to personal computer via USB.Same
MaterialsAssorted electrical components, circuit boards, sound transducers, microphone, electrodes, disposable probe ear tips.Same
SterilityNone requiredSame
BiocompatibilityCompletely BiocompatibleSame
Anatomical SiteEar canal, arms, and headSame
Energy DeliveryStimulation of the ear with sound signalsSame
Where UsedClinical SettingSame
SafetyMeets EN 60601-1Same
Operating Temperature15°C to 40°CSame
Storage Temperature5°C to 50°CSame
Relative Humidity15% to 90% (at 40°C Non-Condensing)Same
Atmospheric PressureNone SpecifiedSame
Mode of OperationContinuousSame
Type of ProtectionClass I (IEC 601)Same
Degree of ProtectionType B (IEC 601)Same
Protection Against FluidsIPX0 - Ordinary Equipment (IEC 601)Same
Degree of MobilityPortable EquipmentSame
Vibration and ShockN/ASame
Expected Lifetime10 Years from date of manufactureSame
Power SupplyExternal medical grade power supply (3 Outputs: +15V, -15V, +5V) OR Internal medical grade power supply (3 Outputs: +15V, -15V, +5V)External medical grade power supply (1 Output: +5V (2A))
Rated Input Current1.3 Amps or 2.0 Amps0.5 Amps
Rated Frequency50-60 HzSame
Rated Input Voltage100-240 VoltsACSame
Rated Max Input Power40 Watts10 Watts
Fuse TypeN/A (External Power Supply) or Time Lag Fuse (IEC 60127-2 compliant)N/A (External Power Supply)
Fuse RatingN/A (External Power Supply) or 1.6 Amps, 250 VoltsACN/A (External Power Supply)
Patient Isolation4000Vdc, 10 Mega OhmsSame
A/D Resolution16 bitSame
Artifact RejectionProgrammableSame
Input ChannelsSmartEP, SmartScreener, SmartEP-ASSR: 1-4 Channels; SmartOAE, SmartTrOAE: 1-2 ChannelsSmart USBLite (EP, Screener, ASSR): 1 Channel; Smart USBLite (DPOAE, TrOAE): 1 Channel
GainSmartEP, SmartScreener, SmartEP-ASSR: Variable (30k-300k); SmartOAE: Fixed (100); SmartTrOAE: Fixed (100)Smart USBLite (EP, Screener, ASSR): Fixed (100k); Smart USBLite (DPOAE): Same; Smart USBLite (TrOAE): Same
Lowpass FilterSmartEP, SmartScreener: Variable (30-5000 Hz); SmartOAE: 100 kHz; SmartTrOAE: 5000 Hz; SmartEP-ASSR: Variable (30-5000 Hz)Smart USBLite (EP, Screener): Fixed (1500 Hz); Smart USBLite (DPOAE): Same; Smart USBLite (TrOAE): Same; Smart USBLite (ASSR): Fixed (300 Hz)
Highpass FilterSmartEP, SmartScreener, SmartEP-ASSR: Variable (1-500 Hz); SmartOAE: 200 Hz; SmartTrOAE: 450 HzSmart USBLite (EP, Screener, ASSR): Fixed (30 Hz); Smart USBLite (DPOAE): Same; Smart USBLite (TrOAE): Same
Filter SlopeSmartEP, SmartScreener, SmartEP-ASSR: 6 dB/octave; SmartTrOAE: 24 dB/octaveSmart USBLite (EP, Screener, ASSR): 12 dB/octave; Smart USBLite (TrOAE): Same
Notch Filter50/60HzSame
Noise LevelSmartEP, SmartScreener, SmartEP-ASSR: 0.33 μV RMS (1-3000 Hz), 0.12 μVpp for 1024 averaged sweeps; SmartOAE, SmartTrOAE: 40 μV RMSSmart USBLite (EP, Screener, ASSR): 0.13 μV RMS (30-1500 Hz), 0.1 μVpp for 1024 averaged sweeps; Smart USBLite (DPOAE, TrOAE): Same
Input ImpedanceOpti-Amp DC Powered: 5 MegaOhmsSame
CMR RatioOpti-Amp DC Powered: 117 dB at 60Hz, 110 dB at 1kHzSame
Auditory Stimuli TypesClicks, Pure Tones, Multifrequency Stimuli, Tone BurstsSame
Duration25-5000 µsec or ContinuousSame
EnvelopesLinear, Blackman, Gaussian, Hanning, Rectangular, Triangular, Trapezoidal, Exact Blackman, Cosine, Cosine Squared, Cosine CubedSame
Intensity0-125 dB SPL (EP/Screener), 55-80 dB SPL (OAE), 60-90 dB SPL (TrOAE), 0-80 dB SPL (ASSR)Same
Repetition Rate1-100 Hz or ContinuousSame
Test Frequencies500-16,000 HzSame
PresentationMonaural or Binaural (EP/Screener/ASSR); Monaural (OAE/TrOAE)Same
MaskingWhite Noise ProgrammableSame
TransducersInsert Earphones, Bone Vibrator, Headphones, Sound Field, Ear ProbeInsert Earphones, Headphones, Ear Probe
Analysis WindowVariable (up to 2.5 msec) or Fixed (25.6 msec, 102.4 msec, 2.5-22.5 msec)Same
Artifact Rejection ThresholdUser Selectable or Automated/FixedSame
Measured ValuesResponse Level, Noise Level, Signal to Noise Ratio, Response Latency, FrequencySame
Computer TypePersonal ComputerSame
Operating SystemMicrosoft Windows 2000 or XPSame
Interface ConnectionUSB (Universal Serial Bus)Same

2. Sample size used for the test set and the data provenance (e.g. country of origin of the data, retrospective or prospective)

The document does not describe a "test set" in the context of clinical data or patient samples. The study is a technical comparison for substantial equivalence. The "test" in this context refers to engineering verification and validation activities to ensure the new device meets its design specifications and electrical safety standards; these do not typically involve patient data.

3. Number of experts used to establish the ground truth for the test set and the qualifications of those experts (e.g. radiologist with 10 years of experience)

Not applicable. No "test set" involving expert-established ground truth for clinical performance is described. The comparison is based on technical specifications and adherence to safety standards.

4. Adjudication method (e.g. 2+1, 3+1, none) for the test set

Not applicable. There is no clinical test set requiring adjudication of ground truth.

5. If a multi reader multi case (MRMC) comparative effectiveness study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

Not applicable. This device is a measurement system, not an AI-assisted diagnostic tool for human readers, and no MRMC study is mentioned.

6. If a standalone (i.e. algorithm only without human-in-the-loop performance) was done

This is not an algorithm-only device. It is a hardware and software system for audiological measurements. The "study" for this submission is a declaration of conformance to design controls and safety standards, and a comparison of technical specifications to predicate devices. It states that "all verification and validation activities have been performed for the Smart USBLite device," and that "The results have demonstrated that all predetermined acceptance criteria have been met." However, no details of these specific verification and validation activities are provided in the summary beyond adherence to general standards (e.g., EN60601-1).

7. The type of ground truth used (expert consensus, pathology, outcomes data, etc.)

Not applicable in the clinical sense. The "ground truth" for the device's technical specifications and safety would be established by engineering standards, testing protocols, and comparison to the predicate devices' established performance. For example, the noise level specifications are a technical measurement, not a clinical "ground truth."

8. The sample size for the training set

Not applicable. This device is not an AI/ML device that requires a training set of data.

9. How the ground truth for the training set was established

Not applicable. This device is not an AI/ML device that requires a training set.

{0}------------------------------------------------

KO61443

    1. 2

JUN 2 3 2006

:

Special 510(k) Summary

:

Prepared By:Intelligent Hearing Systems6860 SW 81st StreetMiami, FL 33143
Telephone:(305) 668-6102
FAX:(305) 668-6103
Contact Person:Edward Miskiel
Date Summary prepared:May 23, 2006
Name of the Device:Smart USBLite (with options of SmartEP, SmartScreener,SmartOAE, SmartTrOAE, and SmartEP-ASSR)
Common Name:Auditory Evoked Potential System & Otoacoustic Device
Classification Name:Auditory Evoked Response Stimulator (per CFR 882.1900)& Audiometer (per CFR 874.1050)
Predicate Device(s):SmartEP (K904926), SmartScreener (K925648), SmartOAE(K964426), SmartTrOAE (K023859), SmartEP-ASSR(K031051), and Opti-Amp DC-Powered (K052060).
Device Description:Smart USBLite is an auditory evoked potential andotoacoustic emission system that is capable of recordingand measuring auditory evoked potential, otoacousticemission, and auditory steady-state evoked potential data.
The Smart USBLite system combines the following FDA510(k) previously cleared devices into a repackaged,smaller-sized, single integrated unit: SmartEP (K904926),SmartScreener (K925648), SmartOAE (K964426),SmartTrOAE (K023859), SmartEP-ASSR (K031051), andOpti-Amp DC-Powered (K052060).
Intended Use:The Smart USBLite device is intended to be used as adiagnostic aid in auditory and hearing related disorders, asan objective measure of cochlear function, and as anadjunctive tool in the estimation of behavioral hearingthresholds on patients of all ages. This is the sameintended use as that of the predicate devices.

・・・・・・・・・

{1}------------------------------------------------

Technological Characteristics:

The Intelligent Hearing Systems (IHS) family of products is intended to be used for recording and analysis of human physiological data for the purpose of neurological diagnosis, screening, and treatment of sensory disorders. The Smart USBLite device referenced above is the latest in a series of systems of this type marketed by IHS. Other related devices comprising the IHS family of products include:

    1. 510(k) #K904926 SmartEP Auditory Evoked Potential System
    1. 510(k) #K904926 SmartScreener Automated Auditory Evoked Potential Screening System
    1. 510(k) #K964426 SmartOAE Distortion-Product Otoacoustic Emissions System
  1. 510(k) #K023859 - SmartTrOAE Transient Otoacoustic Emissions System
    1. 510(k) #K031051 SmartEP-ASSR Auditory Steady-State Response System
  1. 510(k) #K052060 - Opti-Amp DC-Powered Physiological Signal Amplifier System

The feature modifications described in this Special 510(k) are to incorporate a repackaged variation of the listed predicate devices combined into a smaller-sized single integrated unit, the Smart USBLite. The Smart USBLite device is identical to the predicate device(s) in its intended use and methodologies, which have not changed as a result of modifications to the general specifications of the device. The Smart USBLite device can be used to perform all four different kinds of tests provided by the listed predicate devices, namely: auditory evoked potentials (AEP), auditory evoked potential screening, distortionproduct otoacoustic emissions (DPOAE), transient otoacoustic emissions (TrOAE), and auditory steadystate response (ASSR) testing.

The modifications associated with this new Smart USBLite device are mostly to the physical layout and aesthetics of the device hardware only, and do not change the software in any significant way. The new device utilizes hardware variations primarily to enhance size-reduction and portability, while still performing the same hardware functions in essentially the same ways as the predicate devices. The Smart USBLite uses the same five software packages used by the five individual predicate devices (i.e., SmartEP, SmartScreener, SmartOAE, SmartIrOAE, and SmartEP-ASSR software). The software has remained essentially the same for the new device, with small variations to accommodate differences in hardware. The same functionality and user interfaces have remained. Together, these minor hardware and software changes implement the same functionality and perform the same intended uses as the predicate devices in a single integrated unit.

The Smart USBLite hardware is very similar in electronics design to the predicate device hardware, except that the electronics hardware has been repackaged into a single, smaller, stand-alone box. Unlike the predicate devices, there is no separate pre-amplifier unit connected to the patient in the Smart USBLite system. Instead, all of the pre-amplifier electronics have been embedded inside of the SmartUSBLite receiver unit. The same patient isolation methods are used.

Besides packaging, the other minor modifications to the Smart USBLite over the previous devices are the number of input/output channels, gain, and filter specifications/characteristics. A complete comparison between the Smart USBLite and the predicate devices is given in specifications Table 1.

Figures 1-2 give simplified block diagrams for the predicate devices system hardware and the new Smart USBLite system.

{2}------------------------------------------------

Safety and Effectiveness:

The Smart USBLite utilizes many of the same design principles, circuit designs, and operating principles as are used in the predicate devices. All of the modifications of the Smart USBLite device were designed in accordance with procedures that meet FDA QSR Design Control and ISO-13485:2003 specifications.

The Smart USBLite device will be evaluated and certified for both electromagnetic compatibility and electrical safety prior to release, by a certified National Recognized Test Laboratory (NRTL),

Washington Laboratories, Ltd. 7560 Lindbergh Dr. Gaithersburg, Maryland 20879,

which will conduct the appropriate EMI/EMC testing for medical equipment, to elements of the requirements of:

  • . EN60601-1:1990: "Medical Electrical Equipment, Part I : General Requirements for Safety."
  • EN60601-1-2:2001: "Medical Electrical Equipment, Part 1: General Requirements for Safety.2.Collateral . Standard: Electromagnetic Compatibility – Requirements and Tests"
  • . EN55011:1998: "Industrial, Scientific, & Medical (ISM) Radio-Frequency Equipment – Radio Disturbances Characteristics - Limits & Methods of Measurements"
  • EN61000-3-2:1995: "Electromagnetic Compatibility (EMC) Part 3-2:Limits for Harmonic Current . Emissions "
  • EN61000-3-3:1995: "Electromagnetic Compatibility (EMC) Part 3-3: Limits of Voltage Fluctuations and . Flicker in Low-Voltage Supply Systems for Equipment with Rated Current up to 16 A "

{3}------------------------------------------------

Substantial Equivalence Based on Assessment of Performance Data:

The Smart USBLite is substantially equivalent to the predicate SmartEP, SmartOAE, SmartTrOAE, SmartEP-ASSR, and Opti-Amp DC-Powered devices marketed by Intelligent Hearing Systems with FDA 510(k) clearance numbers K904926, K925648, K964426, K023859, K031051, and K052060 (respectively). The intended use of the device has not changed as a result of modifications to the general or electrical specifications of the device(s) listed below.

SPECIFICATIONS

ParameterPredicate DevicesSmartEP (K904926)SmartScreener (K925648)SmartOAE (K964426)SmartTrOAE (K023859)SmartEP-ASSR (K031051)Opti-Amp DC Powered (K052060)Device Under Current 510(k)ReviewSmart USBLite
Intended UseSmartEP: Stimulate, record, &process auditory evoked potentialsSmartScreener: Stimulate, record, &process auditory evoked potentialsusing simplified user interface, withautomated evoked response detectionSmartOAE: Elicitation andmeasurement of distortion productotoacoustic emissionsSmartTrOAE: Elicitation andmeasurement of transient andspontaneous otoacoustic emissionsSmartEP-ASSR: Stimulate, record, &process auditory steady-state evokedpotentials.Same
Indications for UseSmartEP, SmartScreener, & SmartEP-ASSR: The recording & analysis ofphysiological data necessary for thediagnosis of auditory and hearing-related disorders.SmartOAE & SmartTrOAE:Determination of cochlear function inpatients of all ages.Same
Target PopulationAll AgesSame
DesignExternal box housing circuitryconnected to personal computer via aUSB connectionSame
MaterialsAssorted electrical components,circuit boards, sound transducers,microphone, electrodes, anddisposable probe ear tipsSame
SterilityNone requiredSame
BiocompatibilityCompletely BiocompatibleSame
Anatomical SiteEar canal, arms, and headSame
Energy DeliveryStimulation of the ear with soundsignalsSame
Where UsedClinical SettingSame
SafetyMeets EN 60601-1Same
General
Operating Temperature15°C to 40°CSame
Storage Temperature5°C to 50°CSame
Relative Humidity15% to 90% (at 40°C Non-Condensing)Same
Atmospheric PressureNone SpecifiedSame
Mode of OperationContinuousSame
Type of ProtectionClass I (IEC 601)Same
Degree of ProtectionType B (IEC 601)Same
Protection AgainstFluidsIPX0 - Ordinary Equipment(IEC 601)Same
Degree of MobilityPortable EquipmentSame
Vibration and ShockN/ASame
Expected Lifetime10 Years from date of manufactureSame
Electrical Specifications
Power SupplyPredicate Hardware Version # 1:External medical grade power supply3 Outputs: +15V (2.5A), -15V(0.5A), and +5V (5A)ORPredicate Hardware Version # 2:Internal medical grade power supply3 Outputs: +15V (2A), -15V (0.7A)and +5V (5A)External medical grade power supply1 Output: +5V (2A)
Rated Input CurrentPredicate Hardware Version # 1:1.3 AmpsORPredicate Hardware Version # 2:2.0 Amps0.5 Amps
Rated Frequency50-60 HzSame
Rated Input Voltage100-240 VoltsACSame
Rated Max Input Power40 Watts10 Watts
Fuse TypePredicate Hardware Version # 1:N/A (External Power Supply)ORPredicate Hardware Version # 2:Time Lag Fuse (IEC 60127-2compliant)N/A (External Power Supply)
Fuse RatingPredicate Hardware Version # 1:N/A (External Power Supply)ORPredicate Hardware Version # 2:1.6 Amps, 250 VoltsACN/A (External Power Supply)
Patient Isolation4000Vdc, 10 Mega OhmsSame
Data Acquisition
A/D Resolution16 bitSame
Artifact RejectionProgrammableSame
Input ChannelsSmartEP, SmartScreener, SmartEP-ASSR:1-4 Channels (Optically Isolated)SmartOAE, SmartTrOAE:1-2 ChannelsSmart USBLite (EP, Screener,ASSR):1 Channel (Optically Isolated)Smart USBLite (DPOAE, TrOAE):1 Channel (Optically Isolated)
Amplifiers/Filters
GainSmartEP, SmartScreener, SmartEP-ASSR:Variable (30k-300k)SmartOAE:Fixed (100)Smart USBLite (EP, Screener,ASSR):Fixed (100k)Smart USBLite (DPOAE):SameSmart USBLite (TrOAE):Same
Lowpass FilterSmartEP, SmartScreener:Variable (30-5000 Hz)Smart USBLite (EP, Screener):Fixed (1500 Hz)
SmartOAE:100 kHzSmart USBLite (DPOAE):Same
SmartTrOAE:5000 HzSmart USBLite (TrOAE):Same
SmartEP-ASSR:Variable (30-5000 Hz)Smart USBLite (ASSR):Fixed (300 Hz)
Highpass FilterSmartEP, SmartScreener, SmartEP-ASSR:Variable (1-500 Hz)Smart USBLite (EP, Screener, ASSR):Fixed (30 Hz)
SmartOAE:200 HzSmart USBLite (DPOAE):Same
SmartTrOAE:450 HzSmart USBLite (TrOAE):Same
Filter SlopeSmartEP, SmartScreener, SmartEP-ASSR:6 dB/octaveSmart USBLite (EP, Screener, ASSR):12 dB/octave
SmartTrOAE:24 dB/octaveSmart USBLite (TrOAE):Same
Notch Filter50/60HzSame
Noise LevelSmartEP, SmartScreener, SmartEP-ASSR:0.33 μV RMS (1-3000 Hz)0.12 μVpp for 1024 averaged sweepsSmart USBLite (EP, Screener, ASSR):0.13 μV RMS (30-1500 Hz)0.1 μVpp for 1024 averaged sweeps
SmartOAE, SmartTrOAE:40 μV RMSSmart USBLite (DPOAE, TrOAE):Same
Input ImpedanceOpti-Amp DC Powered:5 MegaOhmsSame
CMR RatioOpti-Amp DC Powered:117 dB at 60Hz,110 dB at 1kHzSame
Auditory Stimuli
TypesSmartEP, SmartScreener, SmartEP-ASSR:Clicks, Pure Tones, MultifrequencyStimuliSame
SmartOAE:Multifrequency Tones
SmartTrOAE:Clicks, Tone Bursts
DurationSmartEP, SmartScreener, SmartEP-ASSR, SmartTrOAE:25-5000 µsecSame
SmartOAE:Continuous
EnvelopesLinear, Blackman, Gaussian, Hanning,Rectangular, Triangular, Trapezoidal,Exact Blackman, Cosine, CosineSquared, Cosine CubedSame
IntensitySmartEP, SmartScreener:0-125 dB SPL
SmartOAE:55-80 dB SPLSmartTrOAE:60-90 dB SPLSame
SmartEP-ASSR:0-80 dB SPL
Repetition RateSmartEP, SmartScreener, SmartEP-ASSR:1-100 Hz
SmartOAE:ContinuousSame
SmartTrOAE:1-50 Hz
Test Frequencies500-16,000 HzSame
PresentationSmartEP, SmartScreener, SmartEP-ASSR:Monaural or BinauralSame
SmartOAE, SmartTrOAE:Monaural
MaskingWhite Noise ProgrammableSame
TransducersInsert Earphones, Bone Vibrator,Headphones, Sound Field, Ear ProbeInsert Earphones, Headphones, EarProbe
Analysis & MeasurementParameters
Analysis WindowSmartEP, SmartEP-ASSR:Variable (up to 2.5 msec)Same
SmartScreener:Fixed (25.6 msec)
SmartOAE:Fixed (102.4 msec)SmartTrOAE:Fixed (2.5-22.5 msec post-stimulus)
Artifact RejectionThresholdSmartEP, SmartScreener, SmartEP-ASSR, SmartTrOAE:User SelectableSmartOAE:Automated/FixedSame
Measured ValuesResponse Level (dB SPL)Noise Level (dB SPL)Signal to Noise Ratio (dB SPL)Response Latency (msec)Frequency (Hz)Same
Computer Requirements
Computer TypePersonal ComputerSame
Operating SystemMicrosoft Windows 2000 or XPSame
Interface ConnectionUSB (Universal Serial Bus)Same

Particular (1) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

{5}------------------------------------------------

... and those state and the state and the second and the

.

:: :

{6}------------------------------------------------

and the consideration in the successful control consistence in the consistent of

:

{7}------------------------------------------------

15 4-8 dose of the control control control controlled in

:

{8}------------------------------------------------

Table 1: General, electrical, and performance specifications of predicate devices & current device under Special 510(k) review.

:

{9}------------------------------------------------

Image /page/9/Figure/0 description: This image is a block diagram of predicate device hardware. The diagram includes components such as electrodes, an ear probe, earphones/headphones, and a pre-amplifier labeled as (Opti-Amp DC-Powered). The pre-amplifier has an isolation of 400 Volts DC and 10 MegaOhms, and it connects to a desktop or laptop computer via a fiber optic cable and a predicate hardware receiver unit. The power supply is medical grade and operates at 120/240 Volts, providing +/-15 Volts DC and +5 Volts DC.

Figure 1: Block diagram of the predicate devices hardware system. This system uses an Opti-Amp pre-amplifier unit (refer to FDA 510(k) numbers K914876 and K052060) connected to the patient, which is powered by one of two schemes: 1) Two AA batteries housed internally (K914876), or 2) +15Volts taken from the hardware receiver unit and regulated using a high voltage isolation DC-DC converter (K052060).


.

{10}------------------------------------------------

Image /page/10/Figure/0 description: This image is a block diagram of the Smart USBLite Hardware unit. The diagram shows the different components of the system, including the ear probe, electrodes, desktop or laptop computer, power supply, and earphones or headphones. The Smart USBLite Hardware unit has an isolation of 400 Volts DC, 10 MegaOhms and requires +5 VoltsDC.

Figure 2: Block diagram of the Smart USBLite system. The pre-amplifier electronics are embedded inside the receiver unit so there is no separate pre-amplifier unit. The patient cables are connected directly to the Smart USBLite box. The patient is afforded protection by using a high voltage isolation DC-DC converter (rated up to 4000 volts DC, 10 Mega Ohms), as in K052060. The Smart USBLite system derives its power from a +5V, 2A external medical grade power supply, which meets the appropriate safety requirements (IEC60601-1, UL2601-1, CSA601.1, EN60601-1, and EN60950).

のことになる。

.........

. .

{11}------------------------------------------------

Product Labeling

There have been no changes in intended use, advertisements, and directions for use due to the type of modifications to the original SmartEP, SmartScreener, SmartOAE, SmartTrOAE, and SmartEP-ASSR devices marketed by Intelligent Hearing Systems with FDA 510(k) clearance numbers K904926, K925648, K964426, K023859, and K031051 (respectively). The only changes in product labeling between the predicate device(s) and the device under current Special 510(k) review are in the electrical rating label, which includes a change in the reference model number (M011120) and the power specifications. Both changes have resulted from the modifications mentioned in this Special 510(k). The electrical rating label for the Smart USBLite box is shown in the figure below.

Image /page/11/Figure/2 description: The image shows a product label with various details. It includes the brand name "INTELLIGENT HEARING SYSTEMS" and the product name "Smart USB Lite". The label also contains manufacturing information, such as the year "2006", a reference number "M011120", and a serial number "1-1.0". Additionally, it specifies the power requirements as "+5V DC, 2A, 10W".

Figure 3: Electrical rating label for the Smart USBLite box.

、 ・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・

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Declaration of Conformity:

As required by our risk analysis, all verification and validation activities have been performed for the Smart USBLite device by designated individuals at Intelligent Hearing Systems. The results have demonstrated that all predetermined acceptance criteria have been met, in accordance with our ISO-13485 quality system. All records, including Device Master Records and Design History Files, are available for review upon request.

・・・ ・ 1936年 - 1915-2019 - 1947-1944 - 1987 - 1947 - 1997 - 1992 - 1992 - 1992 - 1992 - 1992 - 1992 - 1992 - 1992 - 1992 - 1992 - 1992 - 1992 - 1992 - 1992 - 1992 - 1992 - 19

... .. .. ..

Edward Miskiel, Ph.D. President & CEO

5/23/06

Date

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Image /page/13/Picture/1 description: The image is a black and white seal for the Department of Health & Human Services - USA. The seal is circular with the text "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" around the perimeter. In the center of the seal is an abstract image of an eagle with three heads.

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

SEP - 6 2006

Intelligent Hearing Systems c/o Mr. Edward Miskiel 6860 S. W. 81st St. Miami, FL 33143

Re: K061443

Trade/Device Name: Smart USBLite (with SmartEP, SmartScreener, SmartOAE, SmartTrOAE, & SmartEP-ASSR) Regulation Number: 21CFR 874.1050 Regulation Name: Audiometer Regulatory Class: II Product Code: GWJ; EWO; GWO; GWL Dated: May 23, 2006: Received: May 24, 2006

Dear Mr. Miskiel:

This letter corrects our substantially equivalent letter of June 23, 2006.

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (sections 531-542 of the Act); 21 CFR 1000-1050.

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Page 2 - Mr. Edward Miskiel

This letter will allow you to begin marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Office of Compliance at (240) 276-0115. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (240) 276-3150 or at its Internet address http://www.fda.gov/cdrh/industry/support/index.html.

Sincerely yours,

M.B. Eghelmsi MD

Malvina B. Eydelman, M.D. Director Division of Ophthalmic and Ear, Nose and Throat Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

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510(k) Number (if known): KD61443

Device Name: Smart USBLite (with options of SmartScreener, SmartOAE, SmartTrOAE, & SmartEP-ASSR)

Indications for Use:

The intended use of the Smart USBLite device system is for the recording of auditory evoked potential, otoacoustic emissions, & auditory steady-state evoked potential data. The product is intended to be used as a diagnostic aid in auditory and hearing related disorders, as an objective measure of cochlear function, and as an adjunctive tool in the estimation of behavioral hearing thresholds on patients of all ages.

The Smart USBLite system combines the following FDA 510(k) previously cleared devices into a repackaged, smaller-sized, single, integrated unit: SmartEP (K904926), SmartScreener (K925648), SmartOAE (K964426), SmartTrOAE (K023859), SmartEP-ASSR (K031051), and Opti-Amp DC-Powered (K052060).

The Smart USBLite is intended to be used by trained personnel in a hospital, nursery, clinic, audiologist's office or other appropriate setting.

The anatomical sites of contact are:

  • (1) The patient's scalp and possibly other body sites with the contact objects being electrodes that are capable of measuring bio-potentials
  • (2) The patient's ear with the contact object being a sound delivery device eartip, headphone, ear probe, or ear cups.

Prescription Use (Per 21 CFR 801.109)

Over-the-Counter Use _

(PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE IF NEEDED)

OR

Concurrence of CDRH, Office of Device Evaluation (ODE)
(Division Sign-Off)
Division of Ophthalmic Ear,
Nose and Throat Devises

510(k) NumberK061443
------------------------
Prescription Use
(Per 21 CFR 801.109)

§ 882.1900 Evoked response auditory stimulator.

(a)
Identification. An evoked response auditory stimulator is a device that produces a sound stimulus for use in evoked response measurements or electroencephalogram activation.(b)
Classification. Class II (performance standards).