K Number
K040832
Device Name
C-PORT ANASTOMOSIS SYSTEM (DEPLOYMENT SYSTEM, CLIP, ACCESSORIES), MODEL FG-000050
Manufacturer
Date Cleared
2005-11-10

(589 days)

Product Code
Regulation Number
878.4300
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
The Cardica® C-Port™ Anastomosis System is intended for the creation of anastomoses in blood vessels and grafts, including use in coronary artery bypass grafting procedures.
Device Description
The Cardica C-Port™ Anastomosis System is a sterile, single-patient use device. The Cardica® C-Port™ Anastomosis System is designed to create a reliable and consistent end-to-side anastomosis between a conduit and a small vessel. The product consists of accessories to assist in conduit loading and a device that completes the anastomosis with stainless steel clips. Once the conduit has been loaded onto the device, and the device positioned against the target vessel, the anastomosis is created by pushing an actuation button.
More Information

No
The device description focuses on mechanical components and the creation of anastomoses using stainless steel clips, with no mention of AI or ML capabilities. The "Mentions AI, DNN, or ML" section explicitly states "Not Found".

Yes
The device is intended for the creation of anastomoses in blood vessels and grafts, including use in coronary artery bypass grafting procedures, which is a therapeutic intervention.

No.
The device is described as an anastomosis system used to create connections between blood vessels and grafts, particularly in bypass grafting procedures. Its function is to facilitate a surgical procedure, not to diagnose a medical condition or disease.

No

The device description explicitly states it is a sterile, single-patient use device consisting of accessories and a device that completes the anastomosis with stainless steel clips, actuated by a button. This clearly describes a physical, hardware-based medical device.

Based on the provided information, the Cardica® C-Port™ Anastomosis System is not an IVD (In Vitro Diagnostic) device.

Here's why:

  • Intended Use: The intended use is for the creation of anastomoses in blood vessels and grafts, specifically in coronary artery bypass grafting procedures. This is a surgical procedure performed directly on the patient's body.
  • Device Description: The device is described as a surgical tool that creates an anastomosis using stainless steel clips. This is a mechanical device used during surgery.
  • Lack of IVD Characteristics: IVD devices are used to examine specimens (like blood, urine, or tissue) outside of the body to provide information about a patient's health. The description of the C-Port system does not involve any such testing of specimens.

Therefore, the Cardica® C-Port™ Anastomosis System is a surgical device, not an In Vitro Diagnostic device.

N/A

Intended Use / Indications for Use

The Cardica® C-Port™ Anastomosis System is intended for the creation of anastomoses in blood vessels and grafts, including use in coronary artery bypass grafting procedures.

Product codes

FZP

Device Description

The Cardica C-Port™ Anastomosis System is a sterile, single-patient use device. The Cardica® C-Port™ Anastomosis System is designed to create a reliable and consistent end-to-side anastomosis between a conduit and a small vessel. The product consists of accessories to assist in conduit loading and a device that completes the anastomosis with stainless steel clips. Once the conduit has been loaded onto the device, and the device positioned against the target vessel, the anastomosis is created by pushing an actuation button.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

blood vessels and grafts, including use in coronary artery bypass grafting procedures.

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Not Found

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies

All necessary bench, animal, and clinical testing has been performed on the C-Port™ Anastomosis System and packaging to ensure substantial equivalence to the predicate devices and to ensure the safety and effectiveness of the device.

Key Metrics

Not Found

Predicate Device(s)

K962043, K020779, K031623, K994160

Reference Device(s)

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information

Not Found

§ 878.4300 Implantable clip.

(a)
Identification. An implantable clip is a clip-like device intended to connect internal tissues to aid healing. It is not absorbable.(b)
Classification. Class II.

0

NOV 1 0 2005

K040832

C-Port Anastomosis System Premarket Notification

APPENDIX A 510(K) SUMMARY

This summary of 510(k) safety and effectiveness information is submitted in accordance with the requirements of SMDA 1990 and 21 CFR $807.92.

Name, Address, Phone and Fax number of the Applicant A. Cardica, Inc.

900 Saginaw Drive Redwood City, CA 94063 Telephone: (650)-364-9975 Fax: (650)-364-3134

B. Contact Persons

Sevrina Ciucci Senior Regulatory Affairs Associate Telephone: (650)-331-7147 Fax: (650)-331-3134

். Date Prepared

March 29, 2004

D. Device Name

.

Trade Name: Cardica® C-Port™ Anastomosis System Classification Name: Cardiovascular Surgical Instruments

E. Device Description

The Cardica C-Port™ Anastomosis System is a sterile, single-patient use device. The Cardica® C-Port™ Anastomosis System is designed to create a reliable and consistent end-to-side anastomosis between a conduit and a small vessel. The product consists of accessories to assist in conduit loading and a device that completes the anastomosis with stainless steel clips. Once the conduit has been loaded onto the device, and the device positioned against the target vessel, the anastomosis is created by pushing an actuation button.

F. Intended Use

The C-Port™ Anastomosis System is intended for the creation of anastomoses in blood vessels and grafts, including use in coronary artery bypass grafting procedures.

G. Substantial Equivalence

The C-Port™ Anastomosis System is substantially equivalent to US Surgical Corporation's Auto Suture™ Modified VCS™ Clip™ Applier (K962043, 21 CFR 878.4800 and the Ethicon ENDOPATH™ and PROXIMATE™ Linear Cutters and Staplers (K020779, 21 CFR 878.4750), and the Coalescent Surgical U-Clip™ (K031623, K994160, 21 CFR 870.4300). The subject device is substantially equivalent to the predicate devices with regard to indications, device characteristics, method of use, labeling, and materials.

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H. Device Testing Results and Conclusion

All necessary bench, animal, and clinical testing has been performed on the C-Port™ Anastomosis System and packaging to ensure substantial equivalence to the predicate devices and to ensure the safety and effectiveness of the device.

·

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Image /page/2/Picture/1 description: The image shows the seal of the Department of Health and Human Services (HHS) of the United States. The seal features a stylized eagle with three lines forming its body and wings, symbolizing health, services, and people. The text "DEPARTMENT OF HEALTH AND HUMAN SERVICES - USA" is arranged in a circular pattern around the eagle.

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

NOV I 0 2005

Cardica. Inc. c/o Ms. Laurie Hook Clinical Affairs Manager 900 Saginaw Drive Redwood City, CA 94063

Re: K040832

Trade Name: Cardica® C-Port™ Anastomosis System Regulation Number: 21 CFR 878.4300 Regulation Name: Implantable Clip Regulatory Class: Class II (Two) Product Code: FZP Dated: August 09, 2005 Received: August 10, 2005

Dear Ms. Hook:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

3

Page 2 - Ms. Laurie Hook

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050. This letter will allow you to begin marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Office of Compliance at (240) 276-0120. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 443-6597 or at its Internet address http://www.fda.gov/cdrh/industry/support/index.html.

Sincerely yours,

Diving R. Vichner

Bram D. Zuckerman, M.D. Director Division of Cardiovascular Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

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APPENDIX F INDICATIONS FOR USE STATEMENT

510(k) Number (if known): K 04 0832

Cardica® C-Port™ Anastomosis System Device Name:

Indications For Use:

The Cardica® C-Port™ Anastomosis System is intended for the creation of anastomoses in blood vessels and grafts, including use in coronary artery bypass grafting procedures.

(PLEASE DO NOT WRITE BELOW THIS LINE - CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Duma R. La chner

(Division Sign-Off) (Division of Cardiovascular Devices

510(k) Number_KO 40 8 3 2

Prescription Use X (Per 21 CFR 801.109) (Optional Format 1-2-9 OR

Over-The-Counter Use