K Number
K033489
Device Name
AGC TOTAL KNEE SYSTEM KNEE, ASCENT TOTAL KNEE SYSTEM, MAXIM COMPLETE KNEE SYSTEM, MAXIM ACCEL KNEE SYSTEM ALSO KNOWN
Manufacturer
Date Cleared
2004-06-02

(211 days)

Product Code
Regulation Number
888.3565
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP Authorized
Intended Use
The indications for Biomet's Non-Cemented Porous Coated Knee Components include: 1) Painful and disabled knee joint resulting from osteoarthritis, rheumatoid arthritis, traumatic arthritis, where one or more compartments are involved. 2) Correction of varus, valgus or posttraumatic deformity 3) Correction of revision of unsuccessful osteotomy, arthrodesis, or failure of previous joint replacement procedure
Device Description
All devices are metallic knee femoral and tibial base-plate components. The components are identical to those cleared in previous 510(k) submissions for cemented application. The porous coated components that are subject of this 510(k) are intended for use with components (tibial bearings, all polyethylene patellar components, non-porous coated femoral and tibial base-plates) previously covered by 510(k) submission for cemented use.
More Information

KID-402, KID-405, KID-408

No
The description focuses on the physical components of a knee replacement system and makes no mention of AI or ML.

Yes
The device is a knee replacement component intended to alleviate pain and disability caused by various arthritic conditions and deformities, which is a therapeutic purpose.

No

The device is a knee implant designed for replacement and correction of knee joint issues, not for diagnosing medical conditions.

No

The device description explicitly states that the devices are "metallic knee femoral and tibial base-plate components," which are hardware components.

Based on the provided text, this device is not an IVD (In Vitro Diagnostic).

Here's why:

  • IVD Definition: In Vitro Diagnostics are medical devices used to perform tests on samples taken from the human body (like blood, urine, or tissue) to detect diseases, conditions, or infections.
  • Device Description: The description clearly states the device is composed of "metallic knee femoral and tibial base-plate components." These are implants designed to be surgically placed within the body.
  • Intended Use: The intended uses describe the conditions the device is intended to treat within the knee joint (osteoarthritis, rheumatoid arthritis, deformities, etc.). This involves surgical intervention and implantation, not laboratory testing of samples.

Therefore, this device falls under the category of a surgical implant or prosthetic device, not an In Vitro Diagnostic.

N/A

Intended Use / Indications for Use

Intended Use: Non-cemented total knee replacement

Indications for Use: The indications for Biomet's Non-Cemented Porous Coated Knee Components include:

    1. Painful and disabled knee joint resulting from osteoarthritis, theumatoid arthritis, traumatic arthritis, where one or more compartments are involved.
    1. Correction of varus, valgus or posttraumatic deformity
    1. Correction of revision of unsuccessful osteotomy, arthrodesis, or failure of previous joint replacement procedure.

Product codes

MBH

Device Description

All devices are metallic knee femoral and tibial base-plate components. The components are identical to those cleared in previous 510(k) submissions for cemented application.

The porous coated components that are subject of this 510(k) are intended for use with components (tibial bearings, all polyethylene patellar components, non-porous coated femoral and tibial base-plates) previously covered by 510(k) submission for cemented use.

Mentions image processing

Not Found

Mentions AI, DNN, or ML

Not Found

Input Imaging Modality

Not Found

Anatomical Site

knee joint

Indicated Patient Age Range

Not Found

Intended User / Care Setting

Prescription Use

Description of the training set, sample size, data source, and annotation protocol

Not Found

Description of the test set, sample size, data source, and annotation protocol

Not Found

Summary of Performance Studies

Clinical and Non-Clinical Testing: None provided

Key Metrics

Not Found

Predicate Device(s)

K833921, K912245, K982869, K994326, K915132, K023546, K031462, K030612, K030623

Reference Device(s)

Not Found

Predetermined Change Control Plan (PCCP) - All Relevant Information

Not Found

§ 888.3565 Knee joint patellofemorotibial metal/polymer porous-coated uncemented prosthesis.

(a)
Identification. A knee joint patellofemorotibial metal/polymer porous-coated uncemented prosthesis is a device intended to be implanted to replace a knee joint. The device limits translation and rotation in one or more planes via the geometry of its articulating surfaces. It has no linkage across-the-joint. This generic type of device is designed to achieve biological fixation to bone without the use of bone cement. This identification includes fixed-bearing knee prostheses where the ultra high molecular weight polyethylene tibial bearing is rigidly secured to the metal tibial base plate.(b)
Classification. Class II (special controls). The special control is FDA's guidance: “Class II Special Controls Guidance Document: Knee Joint Patellofemorotibial and Femorotibial Metal/Polymer Porous-Coated Uncemented Prostheses; Guidance for Industry and FDA.” See § 888.1 for the availability of this guidance.

0

K033489

JUN - 2 2004

510(k) Summary

Applicant/Sponsor: Biomet, Inc.

Contact Person: Patricia Sandborn Beres Senior Regulatory Specialist

Proprietary Names: AGC® Total Knee, Ascent™ Total Knee System, Maxim® Complete Knee System, Maxim® Accel Knee System also known as the Vanguard Knee System

Common Name: Porous coated knee replacement components

Classification Name: Knee ioint patellofemorotibial metal/polymer porous coated uncemented (21 CFR 888.3565)

Legally Marketed Devices To Which Substantial Equivalence Is Claimed: AGC® Total Knee System Knee (K833921, K912245), Ascent™ Total Knee System (K982869, K994326), Maxim® Complete Knee System (K915132), Maxim® Accel Knee System (Vanguard) (K023546), Trabecular Metal Tibial and Patellar Components for the NexGen Knee System (K031462), Genesis II Total Knee System (K030612), Profix Total Knee System (K030623)

Device Description: All devices are metallic knee femoral and tibial base-plate components. The components are identical to those cleared in previous 510(k) submissions for cemented application.

The porous coated components that are subject of this 510(k) are intended for use with components (tibial bearings, all polyethylene patellar components, non-porous coated femoral and tibial base-plates) previously covered by 510(k) submission for cemented use.

Intended Use: Non-cemented total knee replacement

Indications for Use: The indications for Biomet's Non-Cemented Porous Coated Knee Components include:

    1. Painful and disabled knee joint resulting from osteoarthritis, theumatoid arthritis, traumatic arthritis, where one or more compartments are involved.
    1. Correction of varus, valgus or posttraumatic deformity
    1. Correction of revision of unsuccessful osteotomy, arthrodesis, or failure of previous joint replacement procedure.

Summary of Technologies: The devices to be covered by this 510(k) are identical to devices covered by previously cleared 510(k) submissions for cemented application.

Clinical and Non-Clinical Testing: None provided

All trademarks are property of Biomet, Inc.

MAHANG, ADDRESS PO Box 587 Warsaw, IN 46581 058

Smenna, Appriss SO E. Bell Drive Warsaw. IN 1658 !

page 1 of 1

( >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> 5 7 1 . 3 ( x / ( x ) . ( x ) ( x ) ( x ) ( x ) ( ) ( x ) ( ) )

Image /page/0/Picture/23 description: The image shows the number 55 in bold, black font. Above the number 55, there is the word "FAX" in a smaller font size. The image is simple and only contains the number and the word.

F. Man Increation of the more conn

1

Image /page/1/Picture/1 description: The image is a black and white seal for the Department of Health & Human Services - USA. The seal is circular with the text "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" around the edge. In the center of the seal is an abstract image of an eagle.

Public Health Service

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

JUN -- 2 2004

Ms. Patricia Sandborn Beres Senior Regulatory Specialist Biomet Orthopedics, Inc. 56 East Bell Drive P.O. Box 587 Warsaw, Indiana 46581-0587

:

Re: K033489

Trade/Device Name: Biomet's Non-Cemented Porous Coated Knee Components Regulation Number: 21 CFR 888.3565 Regulation Name: Knee joint patellofemorotibial metal/polymer porous-coated uncemented prosthesis. Regulatory Class: II Product Code: MBH Dated: March 3, 2004 Received: March 4, 2004

Dear Ms. Beres:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate for abound in to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

2

Page 2 - Ms. Patricia Sandborn Beres

This letter will allow you to begin marketing your device as described in your Section 510(k) rmarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Office of Compliance at (301) 594-4659. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 443-6597 or at its Internet address http://www.fda.gov/cdrh/dsma/dsmamain.html

Sincerely yours,

Miriam C. Provost

Celia M. Witten, Ph.D., M.D. Director Division of General, Restorative and Neurological Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

3

Indications for Use

510(k) Number (if known): K033489

Device Name: Biomet's Non-Cemented Porous Coated Knee Components

Indications For Use: The indications for Biomet's Non-Cemented Porous Coated Knee Components include:

    1. Painful and disabled knee joint resulting from osteoarthritis, rheumatoid arthritis, traumatic arthritis, where one or more compartments are involved.
    1. Correction of varus, valgus or posttraumatic deformity
    1. Correction of revision of unsuccessful osteotomy, arthrodesis, or failure of previous joint replacement procedure

Prescription Use × (Part 21 CFR 801 Subpart D) AND/OR

Over-The-Counter Use (21 CFR 807 Subpart C)

(PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE IF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Muriam C. Provost

(Division Sign-Off) Division of General, Restorative. and Neurological Devices

Page 1 of 1

510(k) Number K633489