K Number
K031394
Date Cleared
2003-07-25

(84 days)

Product Code
Regulation Number
880.5860
Reference & Predicate Devices
N/A
Predicate For
N/A
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

The American Syringe Company 3cc Syringe is indicated for use in the injection of medication into a patient.

Device Description

Not Found

AI/ML Overview

The provided document is a 510(k) clearance letter from the FDA for the American Syringe Company's 1cc and 3cc Syringe with Needle. It confirms that the device is substantially equivalent to legally marketed predicate devices.

This type of submission does not typically include detailed performance data, acceptance criteria, or clinical study results in the way that, for example, a submission for a new AI-powered diagnostic device would. For syringes, equivalence is often established primarily through design specifications, material conformance to ISO standards, and sometimes physical performance testing against predicate devices, rather than clinical efficacy studies with expert consensus ground truth.

Therefore, many of the requested details are not present in this document. Based on the information available, here's what can be provided:

1. A table of acceptance criteria and the reported device performance

This document does not contain a table of acceptance criteria or reported device performance for the American Syringe Company's 1cc and 3cc Syringe with Needle. For this type of device, acceptance criteria would typically relate to factors like:

  • Dimensional conformity: Meeting specified lengths, diameters, and volumes.
  • Material compatibility: Ensuring materials are non-toxic and compatible with intended medications.
  • Sterility: Ability to maintain sterility until use.
  • Functionality: Smooth plunger movement, secure needle attachment, accurate dose delivery markings, no leakage, sufficient needle sharpness and strength.
  • Biocompatibility: Absence of adverse reactions.
  • Packaging integrity.

2. Sample size used for the test set and the data provenance

Not applicable/Not provided in this document. The 510(k) pathway for a basic device like a syringe often relies on established standards and predicate device comparisons rather than extensive clinical testing with a "test set" of patient data.

3. Number of experts used to establish the ground truth for the test set and the qualifications of those experts

Not applicable/Not provided. Ground truth in the context of expert review for medical imaging or diagnostics is not relevant for a simple medical device like a syringe.

4. Adjudication method for the test set

Not applicable/Not provided.

5. If a multi-reader multi-case (MRMC) comparative effectiveness study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

Not applicable. This device is a syringe, not an AI-powered diagnostic tool.

6. If a standalone (i.e. algorithm only, without human-in-the-loop performance) was done

Not applicable.

7. The type of ground truth used

Not applicable in the conventional sense. For a syringe, "ground truth" would relate to its physical and functional specifications as verified through engineering tests against recognized standards (e.g., ISO standards for syringes and needles), rather than expert consensus or pathology on biological samples.

8. The sample size for the training set

Not applicable. There is no machine learning model or "training set" for a syringe.

9. How the ground truth for the training set was established

Not applicable.

{0}------------------------------------------------

Image /page/0/Picture/1 description: The image shows the logo for the U.S. Department of Health and Human Services. The logo features a stylized eagle with three lines representing its wings and body. The eagle is positioned within a circle that contains the text "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" in a circular arrangement around the eagle.

Public Health Service

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

JUL 2 5 2003

Mr. David M. Garvin President American Syringe Company 1200 Brickell Avenue, Suite 1480 Miami. Florida 33131

Re: K031394

Trade/Device Name: American Syringe Company 1cc and 3CC Syringe with Needle Regulation Number: 880.5860, 880. 5570 Regulation Name: Piston Syringe, Hypodermic Single Lumen Needle Regulatory Class: II Product Code: FMF, FMF, FMI Dated: May 1, 2003 Received: May 2, 2003

Dear Mr. Garvin:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting vour device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

{1}------------------------------------------------

Page 2 - Mr. Garvin

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

This letter will allow you to begin marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits vour device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Office of Compliance at (301) 594-4618. Also, please note the regulation entitled. "Misbranding by reference to premarket notification" (21CFR Part 807.97). You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers. International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 443-6597 or at its Internet address http://www.fda.gov/cdrh/dsma/dsmamain.html

Sincerely yours,

fer

Susan Runner, DDDS, MA Interim Director Division of Anesthesiology, General Hospital Infection Control and Dental Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

{2}------------------------------------------------

ins

INDICATIONS FOR USE

510(k) Number:K031394 (To be assigned by FDA)
Device Name:American Syringe Company 3cc Syringe with Needle
Indications For Use:The American Syringe Company 3cc Syringe is indicated for use in the injection of medication into a patient.

PLEASE DO NOT WRITE BELOW THIS LINE - CONTINUE ON ANOTHER PAGE IF NEEDLED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Prescription Use ✓OR Over - The - Counter Use ✓
-----------------------------------------------------------------------------------------------------------------------------------------------------

(Per 21 CFR 801.109)

Patricia Cucenito

(Division Sign-Off)
Division of Anesthesiology, General Hospital, Division Control, Dental Devices

510(k) Number: K031394

§ 880.5860 Piston syringe.

(a)
Identification. A piston syringe is a device intended for medical purposes that consists of a calibrated hollow barrel and a movable plunger. At one end of the barrel there is a male connector (nozzle) for fitting the female connector (hub) of a hypodermic single lumen needle. The device is used to inject fluids into, or withdraw fluids from, the body.(b)
Classification. Class II (performance standards).