K Number
K023512
Manufacturer
Date Cleared
2003-01-24

(95 days)

Product Code
Regulation Number
892.1550
Reference & Predicate Devices
Predicate For
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

Pie Medical's Picus 3D ultrasound system is intended to be used by a physician to perform general diagnostic ultrasound studies including cardiac, peripheral vascular, fetal, abdominal, small organ, neonatal cephalic, transrectal and transvaginal.

Device Description

Not Found

AI/ML Overview

This 510(k) summary describes a new ultrasound imaging system, the Picus 3D, and compares it to existing predicate devices (Pie Medical 300LC (Picus) K002880 and Esaote AU5 3D K000931) to establish substantial equivalence.

Here's an analysis of the provided information regarding acceptance criteria and studies:

1. A table of acceptance criteria and the reported device performance

The document does not explicitly state "acceptance criteria" or provide a table of performance metrics with specific targets and reported results. Instead, it utilizes a "Comparison Chart for Substantial Equivalence" to demonstrate that the Picus 3D device is comparable in features and functionality to the predicate devices. The underlying acceptance criterion for this submission is that the new device is substantially equivalent to legally marketed predicate devices, meaning it does not raise new questions of safety or effectiveness.

The "reported device performance" is implicitly shown by the detailed feature comparison in the table, demonstrating that the Picus 3D either matches or is equivalent in capability to the predicate devices across various technical specifications and clinical applications. For example, regarding imaging modes, the Picus 3D includes 3D imaging, which was present in one predicate (Esaote AU5 3D K000931) but not the other (Picus K002880), indicating an expansion of capabilities while maintaining equivalence to an existing 3D device.

Here's a summary derived from the comparison chart, focusing on the features presented as comparable for establishing substantial equivalence:

FeaturePredicate 1 (Picus K002880)Predicate 2 (Esaote AU5 3D K000931)Picus 3D (This submission)Acceptance Implication (Substantial Equivalence)
Transducer TypeLinear, ConvexAnnular Array, Mechanical Sector, Linear, Convex, Phased ArrayLinear, ConvexMatches/equivalent to primary predicate K002880, while Esaote offers broader transducer types. All are established technologies.
2D Freq MHz2.5-102.5-152.5-10Matches primary predicate K002880.
PW Freq MHz2.5-82.25-102.5-8Matches primary predicate K002880.
CW Freq MHzNo2.25-5.0NoMatches primary predicate K002880.
Probes MHz (Linear)5.0-105.0-135.0-10Matches primary predicate K002880.
Probes MHz (Convex)2.5-103.5-7.52.5-10Matches primary predicate K002880; broader range than Esaote.
Multifrequency ProbesYesYesYesEquivalent to both predicates.
Special ProbesTransvaginal, TransrectalTransvaginal, Transrectal, Laparoscopic, IntraoperativeTransvaginal, TransrectalEquivalent to primary predicate K002880.
Biopsy AttachmentsConvex, LinearConvex, LinearConvex, LinearEquivalent to both predicates.
3D ImagingNoYesYesMatches predicate Esaote AU5 3D K000931 for 3D functionality.
Real-time 2D ImagingYesYesYesEquivalent to both predicates.
M-modeYesYesYesEquivalent to both predicates.
PW DopplerYesYesYesEquivalent to both predicates.
CW DopplerNoYesNoMatches primary predicate K002880.
CFM DopplerYesYesYesEquivalent to both predicates.
Power DopplerYesYesYesEquivalent to both predicates.
TriplexYesYesYesEquivalent to both predicates.
Monitor Size (inches)SVGA 15SVGA 15SVGA 15Equivalent to both predicates.
Programmability10 presets6 presets10 presetsEquivalent to primary predicate K002880; better than Esaote.
Digital ArchivalYesYesYesEquivalent to both predicates.
VCRYesYesYesEquivalent to both predicates.
Clinical ApplicationsFetal, Abdominal, Small Organ, Neonatal Cephalic, Cardiac, Transrectal, Transvaginal, Peripheral VascularBroader list including Intraoperative, Pediatric, Adult Cephalic, LaparoscopicFetal, Abdominal, Small Organ, Neonatal Cephalic, Cardiac, Transrectal, Transvaginal, Peripheral VascularMatches primary predicate K002880's scope.
Safety (Electrical)IEC 60601-1IEC 60601-1IEC 60601-1Equivalent to both predicates.
Safety (Ultrasound)Track 3 (AOD)Track 3 (AOD)Track 3 (AOD)Equivalent to both predicates.

2. Sample size used for the test set and the data provenance (e.g. country of origin of the data, retrospective or prospective)

This 510(k) summary does not mention any specific test set sample sizes, data provenance, or details of a clinical study for demonstrating performance. This type of submission relies on the concept of substantial equivalence to predicate devices that have already demonstrated safety and effectiveness through their prior market clearance. The data provenance would implicitly refer to the existing clinical use and safety record of the predicate devices.

3. Number of experts used to establish the ground truth for the test set and the qualifications of those experts (e.g. radiologist with 10 years of experience)

Not applicable. As noted above, this 510(k) submission establishes substantial equivalence through feature comparison, not new clinical performance data with ground truth established by experts.

4. Adjudication method (e.g. 2+1, 3+1, none) for the test set

Not applicable. No new test set requiring adjudication is described.

5. If a multi reader multi case (MRMC) comparative effectiveness study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

Not applicable. This is not an AI/CAD-focused device and no MRMC study is mentioned.

6. If a standalone (i.e. algorithm only without human-in-the-loop performance) was done

Not applicable. This is an ultrasound imaging system, which is a human-in-the-loop device by nature (operated by a sonographer/physician).

7. The type of ground truth used (expert consensus, pathology, outcomes data, etc.)

Not applicable. No new ground truth establishment is described for this submission. The "ground truth" for demonstrating safety and effectiveness relies on the established performance and safety profiles of the predicate ultrasound devices already on the market.

8. The sample size for the training set

Not applicable. This is not a machine learning or AI-based device that would typically require a training set.

9. How the ground truth for the training set was established

Not applicable. No training set is described.

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K023512

510(k) Summary Picus 3D Pie Medical

JAN 2 4 2003

510(k) Summary

The following safety and effectiveness summary has been prepared pursuant to requirement for 510(k) summaries specified in 21CFR 807.92(a).

807.92(a)(1)

Submitter Information

Colleen Hittle, Official Correspondent

8000 Castleway Drive

Indianapolis, IN 46250

Phone:(317) 849-1916
Facsimile:(317) 5779070
Contact Person:Colleen Densmore
Date:October 17, 2002

807.92(a)(2)

Trade Name:Picus Ultrasound Imaging Systems
Common Name:Ultrasound Imaging System
Classification Name(s):Ultrasonic pulsed doppler imaging system 892.1550Ultrasonic pulsed echo imaging system 892.1560
Classification Number:90IYN90IYO

807.92(a)(3)

Predicate Device(s)

Pie300LC (Picus) K002880
EsaoteAU5 3D K000931

FDA/CDRH/ODE/PMO

2002 OCT 21 A 10:11

RECEIVED

Additional Substantial Equivalence Information is provided in the following substantial Equivalence Comparison Table.

{1}------------------------------------------------

510(k) Summary Picus 3D Pie Medical

807.92(a)(5)

Device Description

Intended Use(s)

Pie Medical's Picus 3D ultrasound system is intended to be used by a physician to perform general diagnostic ultrasound studies including cardiac, peripheral vascular, fetal, abdominal, small organ, neonatal cephalic, transrectal and transvaginal.

{2}------------------------------------------------

510(k) Summary
Picus 3D
Pie Medical

Comparison Chart for Substantial Equivalence
General characteristicsPicus K002880Esaote AU5 3D K000931Pie Medical Picus 3DThis submission
Transducer type
Annular ArrayNoYesNo
Mechanical SectorNoYesNo
LinearYesYesYes
ConvexYesYesYes
Phased arrayNoYesNo
2D Freq MHz2.5-102.5 - 152.5-10
PW Freq MHz2.5-82.25 - 102.5-8
CW Freq MHzNo2.25 - 5.0No
Probes MHz
Annular Array-10 - 20-
Linear5.0-105.0 - 135.0-10
Convex2.5-103.5 - 7.52.5 - 10
Phased array-2.5 - 3.5-
Multifrequency probesYesYesYes
Special probesTransvaginalTransrectalTransvaginalTransrectalLaparoscopicIntraoperativeTransvaginalTransrectal
Biopsy attachments---
ConvexYesYesYes
LinearYesYesYes
Imaging modes
3DNoYesYes
Real time 2DYesYesYes
M-modeYesYesYes
PW DopplerYesYesYes
CW DopplerNoYesNo
CFM DopplerYesYesYes
Power DopplerYesYesYes
TriplexYesYesYes
Monitor size (inches)SVGA 15SVGA 15SVGA 15
Programmability10 presets6 presets10 presets
Pulsed DopplerYesYesYes
CW DopplerNoYesNo
Audio stereoYesYesYes
Color DopplerYesYesYes
ECGOptionalOptionalOptional
General characteristicsPicus K002880Esaote AU5 3D K000931Pie Medical Picus 3D This submission
Digital archival capabilitiesYesYesYes
General characteristicsPicus K002880Esaote AU5 3D K000931Pie Medical Picus 3D
VCRYesYesYes
M&A CapabilitiesFetal, abdominal, small organ, neonatal cephalic, cardiac, transrectal, transvaginal & peripheral vascularFetal, abdominal, intraoperative abdominal, pediatric, small organ, neonatal cephalic, adult cephalic, cardiac, transrectal, transvaginal, peripheral vascular & laparoscopicFetal, abdominal, small organ, neonatal cephalic, cardiac, transrectal, transvaginal & peripheral vascular
Safety
ElectricalIEC 60601-1IEC 60601-1IEC 60601-1
UltrasoundTrack 3 (AOD)Track 3 (AOD)Track 3 (AOD)

Comparison Chart for Substantial Equivalence

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{4}------------------------------------------------

Image /page/4/Picture/2 description: The image shows the logo for the U.S. Department of Health & Human Services. The logo consists of a circular seal with the text "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" around the perimeter. Inside the circle is an abstract image of an eagle or bird with outstretched wings.

JAN 2 4 2003

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

Pie Medical % Ms. Colleen Densmore The Anson Group 7992 Castleway Drive INDIANAPOLIS IN 46250

Re: K023512

Trade Name: Picus Ultrasound Imaging System Regulation Number: 21 CFR 892.1550 Regulation Name: Ultrasonic pulsed doppler imaging system Regulation Number: 21 CFR 892.1560 Regulation Name: Ultrasonic pulsed echo imaging system Regulation Number: 21 CFR 892.1570 Regulation Name: Diagnostic ultrasonic transducer Regulatory Class: II Product Code: 90 IYN, IYO, and ITX Dated: December 19, 2002 Received: December 20, 2002

Dear Ms. Densmore:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and we have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

This determination of substantial equivalence applies to the following transducers intended for use with the Picus Ultrasound Imaging System, as described in your premarket notification:

Transducer Model Number

3.5 MHz R40 Convex array 3.5 MHz R60 Convex array 7.0 MHz R10 Convex array 7.5 MHz L40 Linear array

{5}------------------------------------------------

7.5 MHz L50 Linear array 9.5 MHz EC123 Convex array

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register. Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

This letter will allow you to begin marketing your device as described in your premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus permits your device to proceed to market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801, please contact the Office of Compliance at (301) 594-4591. Additionally, for questions on the promotion and advertising of your device, please contact the Office of Compliance at (301) 594-4639. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21 CFR Part 807.97). Other general information on your responsibilities under the Act may be obtained from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or at (301) 443-6597 or at its Internet address "http://www.fda.gov/cdrh/dsmamain.html".

If you have any questions regarding the content of this letter, please contact Rodrigo C. Perez at (301) 594-1212.

Sincerely yours,

Nancy C Brogdon

Nancy C. Brogdon Director, Division of Reproductive, Abdominal and Radiological Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure(s)

{6}------------------------------------------------

Picus

System
Mode of Operation
Clinical applicationABMPWDColorDopplerAmplitudeDopplerColorVelocityImagingCombined(specify)Other(specify)3D
Ophthalmic
FetalPPPPPN
AbdominalPPPPPN
Intraoperative (specify)
Intraoperative Neurological
Pediatric
Small Organ (specify) *PPPPPN
Neonatal CephalicPPPPPN
Adult Cephalic
CardiacPPPPPN
Transesophageal
TransrectalPPPPPN
TransvaginalPPPPPN
Transurethral
Intravascular
Peripheral VascularPPPPPN
Laparoscopic
Musculo-skeletal
Conventional
Musculoskeletal Superficial
Other (specify)

N=new indication P=previously cleared by FDA E=added under Appendix E

Additional comments:

  • Small organs include Thyroid, Breast and Testicles

Prescription Use

Nancy C Brogdon
(Division Sign-Off)

Division of Reproductive" Abdominal and Radiological Devices 510(k) Number -

{7}------------------------------------------------

Picus

#410501

3.5Mhz R40 Convex array

Mode of Operation
Clinical applicationABMPWDColorDopplerAmplitudeDopplerColorVelocityImagingCombined(specify)Other(specify)3D
Ophthalmic
FetalPPPPPN
AbdominalPPPPPN
Intraoperative (specify)
Intraoperative Neurological
Pediatric
Small Organ (specify) *
Neonatal Cephalic
Adult Cephalic
Cardiac
Transesophageal
Transrectal
Transvaginal
Transurethral
Intravascular
Peripheral VascularPPPPPN
Laparoscopic
Musculo-skeletal
Conventional
Musculoskeletal Superficial
Other (specify)

N=new indication P=previously cleared by FDA E=added under Appendix E

Additional comments:

Prescription Use

Nancy C Brogdon
(Division Sign-Off)

Division of Reproductive A and Radiclogical Devices 510(k) Number ________________________________________________________________________________________________________________________________________________________________ KOZ 3512

{8}------------------------------------------------

Picus

#410502

3.5Mhz R60 Convex array

Mode of Operation
Clinical applicationABMPWDColorDopplerAmplitudeDopplerColorVelocityImagingCombined(specify)Other(specify)3D
Ophthalmic
FetalPPPPPN
AbdominalPPPPPN
Intraoperative (specify)
Intraoperative Neurological
Pediatric
Small Organ (specify) *
Neonatal Cephalic
Adult Cephalic
Cardiac
Transesophageal
Transrectal
Transvaginal
Transurethral
Intravascular
Peripheral VascularPPPPPN
Laparoscopic
Musculo-skeletal
Conventional
Musculoskeletal Superficial
Other (specify)

N=new indication P=previously cleared by FDA E=added under Appendix E

Additional comments:

Prescription Use

Nancy C Brogdon

(Division Sign-Off) ( Division of Reproductive, Abdominal, and Radiological Devices 510(k) Number _

{9}------------------------------------------------

Picus

#410504

7.0Mhz R10 Convex array

Mode of Operation
Clinical applicationABMPWDColorDopplerAmplitudeDopplerColorVelocityImagingCombined(specify)Other(specify)3D
Ophthalmic
Fetal
Abdominal
Intraoperative (specify)
Intraoperative Neurological
Pediatric
Small Organ (specify) *
Neonatal Cephalic
Adult Cephalic
Cardiac
Transesophageal
TransrectalPPPPPN
TransvaginalPPPPPN
Transurethral
Intravascular
Peripheral Vascular
Laparoscopic
Musculo-skeletal
Conventional
Musculoskeletal Superficial
Other (specify)

N=new indication P=previously cleared by FDA E=added under Appendix E

Additional comments:

Prescription Use

Nancy C. Broaddus

(Division Sign-Off) Division of Reproductive, Abdominal, and Radiological Devices 510(k) Number ________________________________________________________________________________________________________________________________________________________________ 023

{10}------------------------------------------------

Picus

#410503

7.5Mhz L40 Linear array

Mode of Operation
Clinical applicationABMPWDColorDopplerAmplitudeDopplerColorVelocityImagingCombined(specify)Other(specify)3D
Ophthalmic
Fetal
Abdominal
Intraoperative (specify)
Intraoperative Neurological
Pediatric
Small Organ (specify) *PPPPPN
Neonatal Cephalic
Adult Cephalic
Cardiac
Transesophageal
Transrectal
Transvaginal
Transurethral
Intravascular
Peripheral VascularPPPPPN
Laparoscopic
Musculo-skeletal
Conventional
Musculoskeletal Superficial
Other (specify)

N=new indication P=previously cleared by FDA E=added under Appendix E

Additional comments:

Prescription Use

Nancy C. Brogdon
(Division Sign-Off)

Division of Reproductive, Abdominal, and Radiological Devices 510(k) Number _

{11}------------------------------------------------

Picus

#410506

7.5Mhz L50 Linear array

Clinical applicationABMPWDColorDopplerAmplitudeDopplerColorVelocityImagingCombined(specify)Other(specify)3D
Ophthalmic
Fetal
Abdominal
Intraoperative (specify)
Intraoperative Neurological
Pediatric
Small Organ (specify) *PPPPPN
Neonatal Cephalic
Adult Cephalic
Cardiac
Transesophageal
Transrectal
Transvaginal
Transurethral
Intravascular
Peripheral VascularPPPPPN
Laparoscopic
Musculo-skeletal
Conventional
Musculoskeletal Superficial
Other (specify)

N=new indication P=previously cleared by FDA E=added under Appendix E

Additional comments:

  • Small organs include Thyroid, Breast and Testicles

Prescription Use

Nancy Brogdon
(Division Sign-Off)
Division of Reproductive, Abdominal

(Division of Reproductive, Abdominal, and Radiological Devices 510(k) Number ___

{12}------------------------------------------------

Picus

#410729

9.5Mhz EC123 Convex array

Mode of OperationCompany of Children第一位被害者有官方法181 01:08 PM
Clinical application ------1990 - 2007 - 2007 - 2008 - 2008 - 2008 - 2008 - 2008 - 2008 - 2000 - 2000 - 2000 - 2000 - 2000 - 2000 - 2000 - 2000 - 2000 - 2000 - 2000 - 2000 - 2000 - 2000 - 2000 - 2000ABM:PWDColor .DopplerAmplitudeDoppler. ColorVelocityImagingCombined(specify)Other(specify)3D
Ophthalmic -------
Fetal Party - 1993 114
Abdominal Amaria.
Intraoperative (specify)
Intraoperative Neurological
Pediatric ====================================================================================================================================================================
Small Organ (specify) *
Neonatal Cephalic
Adult Cephalic
Cardiac
Transesophageal
TransrectalEEEEEN
TransvaginalEEEEEN
Transurethral
Intravascular
Peripheral Vascular
Laparoscopic
Musculo-skeletal
Conventional
Musculoskeletal Superficial
Other (specify)

N=new indication P=previously cleared by FDA E=added under Appendix E

Additional comments:

  • Small organs include Thyroid, Breast and Testicles

Prescription Use /

Nancy C hogdon

l
The Company of the Children Children the Children the Children the Children the Children the Children the Children the Children the Children the Children the Children the C

(Division Sign-Off) Division of Reproductive, Abdominal, and Radiological Devices 510(k) Number ________________________________________________________________________________________________________________________________________________________________ KO225

§ 892.1550 Ultrasonic pulsed doppler imaging system.

(a)
Identification. An ultrasonic pulsed doppler imaging system is a device that combines the features of continuous wave doppler-effect technology with pulsed-echo effect technology and is intended to determine stationary body tissue characteristics, such as depth or location of tissue interfaces or dynamic tissue characteristics such as velocity of blood or tissue motion. This generic type of device may include signal analysis and display equipment, patient and equipment supports, component parts, and accessories.(b)
Classification. Class II.