K Number
K201691
Date Cleared
2020-09-17

(87 days)

Product Code
Regulation Number
878.4040
Reference & Predicate Devices
Predicate For
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

The Single-Use Surgical Mask with Ear Loop is intended to be worn to protect both the patient and healthcare personnel from the transfer of microorganisms, body fluids, and particulate material. The Single-Use Surgical Mask with Ear Loop intended for use in infection control practices to reduce the potential exposure to blood and body fluids. This is a single-use, disposable device(s), provided non-sterile. Model: M and L, blue color, and Level 2 barrier level as ASTM F2100.

Device Description

The proposed device(s) are Blue color, and Flat Pleated type mask, utilizing Ear Loops' way for wearing, and they all have Nose Piece design for fitting the facemask around the nose. The proposed device(s) are manufactured with three layers, the inner and outer layers are made of PP spun-bond non-woven fabric, and the middle layer is made of Melt-blown non-woven fabric. The blue colorant is bule masterbatch. The Single-Use Surgical Mask with Ear Loop is held in place over the user's mouth and nose by two elastic ear loops welded to the facemask. The elastic ear loops are made with Polyester. The nose piece contained in the proposed device(s) is in the layers of the facemask to allow the user to fit the facemask around their nose, which is made of malleable aluminum wire. The proposed device(s) are sold non-sterile and are intended to be single-use, disposable devices. There are two models included, Model M and L. The two models share the same indication for use, instruction for use, material used, and structure. The only difference is the dimension.

AI/ML Overview

The provided text describes the acceptance criteria and study results for the "Single-Use Surgical Mask with Ear Loop" (K201691), demonstrating its substantial equivalence to a predicate device (K153496).

Here's a breakdown of the requested information:

1. Table of Acceptance Criteria and Reported Device Performance:

Name of the Test Methodology/StandardPurposeAcceptance CriteriaReported Device Performance (K201691)
ASTM F1862Resistance to penetration by synthetic blood120 mm Hg120 mm Hg (31 out of 32 pass)
ASTM F2299Sub-micron particulate filtration efficiency at 0.1 micron≥ 98%>99%
ASTM F2101Bacterial Filtration Efficiency≥ 98%>99%
MIL-M-36954CDifferential Pressure< 6.0 mm H2O/cm²< 5.0 mm H2O/cm²
16 CFR 1610FlammabilityClass 1Class 1
ISO 10993-5CytotoxicityNo cytotoxicity effectUnder the conditions of the study, no cytotoxicity
ISO 10993-10IrritationNo irritation effectUnder the conditions of the study, no irritation
SensitizationNo sensitization effectUnder conditions of the study, no sensitization

2. Sample Size Used for the Test Set and Data Provenance:

The document doesn't explicitly state the sample sizes for all tests beyond the Fluid Resistance (ASTM F1862) test, which mentions "31 out of 32 pass." The provenance of the data is not specifically detailed, but the tests were conducted to demonstrate compliance with various ASTM and ISO standards. The sponsor, Qiqihar Hengxin Medical Supplies, Ltd., is located in China, suggesting the testing likely occurred there or at a certified lab. The document does not specify if the studies were retrospective or prospective, though performance testing for regulatory submission is typically conducted prospectively.

3. Number of Experts Used to Establish Ground Truth and Qualifications:

This information is not applicable. The evaluations are based on standardized laboratory performance tests, not expert interpretation of diagnostic images or clinical data requiring ground truth establishment by human experts.

4. Adjudication Method for the Test Set:

This information is not applicable. The evaluations are based on objective measurements from standardized performance tests, not subjective interpretations requiring adjudication.

5. If a Multi-Reader Multi-Case (MRMC) Comparative Effectiveness Study Was Done:

No, an MRMC comparative effectiveness study was not done. The device is a surgical mask, and its evaluation relies on physical and biological barrier performance, not human reader interpretation of data.

6. If a Standalone (Algorithm Only Without Human-in-the-Loop Performance) Was Done:

This question is not applicable to a physical medical device like a surgical mask. There is no algorithm or AI involved in its function that would require "standalone" performance testing. The evaluation focuses on the mask's inherent physical and material properties.

7. The Type of Ground Truth Used:

The "ground truth" for the performance evaluation of this device is established by the prescribed methodologies and specifications of the referenced international standards (ASTM F1862, ASTM F2299, ASTM F2101, MIL-M-36954C, 16 CFR 1610, ISO 10993-5, ISO 10993-10). These standards define objective, measurable criteria for fluid resistance, filtration efficiency, differential pressure, flammability, cytotoxicity, irritation, and sensitization.

8. The Sample Size for the Training Set:

This information is not applicable. The device is a physical medical device (surgical mask) and not an AI/ML-based algorithm. Therefore, there is no "training set" in the context of machine learning.

9. How the Ground Truth for the Training Set Was Established:

This information is not applicable, as there is no training set for this type of device.

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Image /page/0/Picture/0 description: The image shows the logo of the U.S. Food and Drug Administration (FDA). On the left is the Department of Health & Human Services logo. To the right of that is the FDA logo, which is a blue square with the letters "FDA" in white. To the right of the blue square is the text "U.S. FOOD & DRUG ADMINISTRATION" in blue.

September 17, 2020

Qiqihar Hengxin Medical Supplies, Ltd. % Ray Wang General Manager Beijing Believe-Med Technology Service Co., Ltd Rm.912, Building #15, XiYueHui, No.5, YiHe North Rd., FangShan District Beijing, Beijing 102401 China

Re: K201691

Trade/Device Name: Single-Use Surgical Mask With Ear Loop Regulation Number: 21 CFR 878.4040 Regulation Name: Surgical Apparel Regulatory Class: Class II Product Code: FXX Dated: August 18, 2020 Received: August 21, 2020

Dear Ray Wang:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. Although this letter refers to your product as a device, please be aware that some cleared products may instead be combination products. The 510(k) Premarket Notification Database located at https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpmn/pmn.cfm identifies combination product submissions. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you, however, that device labeling must be truthful and not misleading.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

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Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); medical device reporting of medical device-related adverse events) (21 CFR 803) for devices or postmarketing safety reporting (21 CFR 4, Subpart B) for combination products (see https://www.fda.gov/combination-products/guidance-regulatory-information/postmarketing-safety-reportingcombination-products); good manufacturing practice requirements as set forth in the quality systems (OS) regulation (21 CFR Part 820) for devices or current good manufacturing practices (21 CFR 4, Subpart A) for combination products; and, if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21 CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to https://www.fda.gov/medical-device-safety/medical-device-reportingmdr-how-report-medical-device-problems.

For comprehensive regulatory information about medical devices and radiation-emitting products, including information about labeling regulations, please see Device Advice (https://www.fda.gov/medicaldevices/device-advice-comprehensive-regulatory-assistance) and CDRH Learn (https://www.fda.gov/training-and-continuing-education/cdrh-learn). Additionally, you may contact the Division of Industry and Consumer Education (DICE) to ask a question about a specific regulatory topic. See the DICE website (https://www.fda.gov/medical-device-advice-comprehensive-regulatoryassistance/contact-us-division-industry-and-consumer-education-dice) for more information or contact DICE by email (DICE@fda.hhs.gov) or phone (1-800-638-2041 or 301-796-7100).

Sincerely.

For CAPT Elizabeth Claverie, M.S. Assistant Director DHT4B: Division of Infection Control and Plastic Surgery Devices OHT4: Office of Surgical and Infection Control Devices Office of Product Evaluation and Quality Center for Devices and Radiological Health

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Indications for Use

510(k) Number (if known) K201691

Device Name Single-Use Surgical Mask with Ear Loop

Indications for Use (Describe)

The Single-Use Surgical Mask with Ear Loop is intended to be worn to protect both the patient and healthcare personnel from the transfer of microorganisms, body fluids, and particulate material. The Single-Use Surgical Mask with Ear Loop intended for use in infection control practices to reduce the potential exposure to blood and body fluids. This is a single-use, disposable device(s), provided non-sterile.

Model: M and L, blue color, and Level 2 barrier level as ASTM F2100.

Type of Use (Select one or both, as applicable)

Prescription Use (Part 21 CFR 801 Subpart D)

Over-The-Counter Use (21 CFR 801 Subpart C)

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K201691

510(k) Summary

This 510(k) Summary of 510(k) safety and effectiveness information is being submitted in accordance with requirements of SMDA 1990 and Title 21, CFR Section 807.92.

    1. Date of Preparation: 2020/09/17
    1. Sponsor Identification

Qiqihar Hengxin Medical Supplies, Ltd.

10th Beijiang Road in Tiefeng Industrial Park, North Shuguang Ave. Tiefeng District, Qiqihar, Heilongjiang Province, China, 161000

Contact Person: Sihui Xiong Position: Commercial Manager Tel: +86-452-5656959 Email: 476923513@qq.com

    1. Designated Submission Correspondent
      Mr. Ray Wang

Beijing Believe-Med Technology Service Co., Ltd.

Rm.912, Building #15, XiYueHui, No.5, YiHe North Rd., FangShan District, Beijing, 102401, China

Tel: +86-18910677558 Fax: +86-10-56335780 Email: Ray.Wang(@believe-med.com

    1. Identification of Proposed Device
      Trade Name: Single-Use Surgical Mask with Ear Loop Common Name: Surgical Face Mask Model(s): M, L;

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Regulatory Information Classification Name: Surgical Face Mask Classification: II Product Code: FXX Regulation Number: 878.4040 Review Panel: Surgical Apparel

Indication for use Statement:

The Single-Use Surgical Mask with Ear Loop is intended to be worn to protect both the patient and healthcare personnel from the transfer of microorganisms, body fluids, and particulate material. The Single-Use Surgical Mask with Ear Loop intended for use in infection control practices to reduce the potential exposure to blood and body fluids. This is a single-use, disposable device(s), provided nonsterile. Model: M and L, blue color, Level 2 barrier level as ASTM F2100.

Device Description

The proposed device(s) are Blue color, and Flat Pleated type mask, utilizing Ear Loops' way for wearing, and they all have Nose Piece design for fitting the facemask around the nose.

The proposed device(s) are manufactured with three layers, the inner and outer layers are made of PP spun-bond non-woven fabric, and the middle layer is made of Melt-blown non-woven fabric. The blue colorant is bule masterbatch.

The Single-Use Surgical Mask with Ear Loop is held in place over the user's mouth and nose by two elastic ear loops welded to the facemask.

The elastic ear loops are made with Polyester.

The nose piece contained in the proposed device(s) is in the layers of the facemask to allow the user to fit the facemask around their nose, which is made of malleable aluminum wire.

The proposed device(s) are sold non-sterile and are intended to be single-use, disposable devices.

There are two models included, Model M and L. The two models share the same indication for use, instruction for use, material used, and structure. The only difference is the dimension.

Identification of Predicate Device(s) న్.

Predicate Device K153496 Disposable Surgical Face Mask Xiantao Rayxin Medical Products Co., Itd.

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Substantially Equivalent (SE) Comparison 6.

ITEMProposed Device K201691Predicate Device K153496Remark
Intended UseThe Single-Use Surgical Mask with EarLoop is intended to be worn to protect boththe patient and healthcare personnel fromthe transfer of microorganisms, body fluids,and particulate material. The Single-UseSurgical Mask with Ear Loop intended foruse in infection control practices to reducethe potential exposure to blood and bodyfluids. This is a single-use, disposabledevice(s), provided non-sterile.The Disposable Surgical Face Masks areintended to be worn to protect both thepatient and healthcare personnel fromtransfer of microorganisms, body fluidsand particulate material. These face masksare intended for use in infection controlpractices to reduce the potential exposureto blood and body fluids. This is a singleuse, disposable device(s), provided non-sterile.SAME
Basic DesignEar Loops, Flat Pleated, 3 layersEar Loops, Tie-On, Flat Pleated, 3 layersSAME
MaterialsOuter Facing LayerSpun-bond non-woven fabricSpun-bond polypropyleneSAME
Middle LayerMelt blown non-woven fabricMelt blown polypropylene filter
Inner Facing LayerSpun-bond non-woven fabricSpun-bond polypropylene
Nose PieceMalleable aluminum wireMalleable aluminum wire
Ear LoopsPolyesterPolyester
ColorBlueBlueSAME
Dimension (Length)Model M: 14 cm +/- 1cmModel L: 18 cm +/- 1cm17.5 cm +/- 1cmSIMILAR
Dimension (Width)9 cm +/- 1cm9.5 cm +/- 1cm
OTC useYesYesSAME
Single UseYesYesSAME
SterileNoNoSAME
ASTM F2100 LevelLevel 2Level 2SAME

Table 2 General Comparison

Table 3 Performance Characteristic Comparison

ITEMProposedDeviceK201691Predicate DeviceK153496ASTM F2100Requirements forLevel 2 ClassificationRemark
Fluid ResistancePerformance ASTMF186231 out of 32 pass at 120 mmHg31 out of 32 pass at 120 mmHg29 out of 32 pass at 120 mmHgSIMILAR
Particulate FiltrationEfficiency ASTMF2299>99%98.46%$\geq$ 98%
Bacterial FiltrationEfficiency ASTM>99%98.7%$\geq$ 98%

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F2101
Differential Pressure(Delta P) MIL-M-36954C< 5.0 mmH2O/cm²4.2 mmH2O/cm²< 6.0 mmH2O/cm²
Flammability16 CFR 1610Class 1Class 1Class 1SAME

Table 4 Biocompatibility Comparison

ITEMProposed Device K201691Predicate Device K153496Remark
CytotoxicityUnder the conditions of the study, nocytotoxicity effectComply with ISO 10993-5SAME
IrritationUnder the conditions of the study, noirritation effectComply with ISO 10993-10SAME
SensitizationUnder conditions of the study, nosensitization effectSAME

7. Summary of Non-Clinical Testing

The following performance data has been provided to demonstrate that the subject device meet the acceptance criteria in the standard.

Name of the TestMethodology/standardPurposeAcceptance CriteriaResults
ASTM F1862Resistance to penetrationby synthetic blood120 mm Hg120 mm Hg
ASTM F2299Sub-micron particulatefiltration efficiency at 0.1micron≥ 98%>99%
ASTM F2101Bacterial FiltrationEfficiency≥ 98%>99%
MIL-M-36954CDifferential Pressure< 6.0 mm H2O/cm²< 5.0 mm H2O/cm²
16 CFR 1610FlammabilityClass 1Class 1
ISO 10993-5IrritationNo irritation effectUnder the conditionsof the study, noirritation effect
SensitizationNo sensitizationeffectUnder conditions ofthe study, nosensitization effect
ISO 10993-10CytotoxicityNo cytotoxicity effectUnder the conditionsof the study, nocytotoxicity effect

Table 1 Non-Clinical Testing

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8. Summary of Clinical Testing

No clinical study is included in this submission.

9. Conclusion

The conclusions drawn from the nonclinical tests demonstrate that the subject device, Single-Use Surgical Mask with Ear Loop, is as safe, as effective, and performs as well as or better than the legally marketed predicate device, Disposable Surgical Face Mask (K153496).

§ 878.4040 Surgical apparel.

(a)
Identification. Surgical apparel are devices that are intended to be worn by operating room personnel during surgical procedures to protect both the surgical patient and the operating room personnel from transfer of microorganisms, body fluids, and particulate material. Examples include surgical caps, hoods, masks, gowns, operating room shoes and shoe covers, and isolation masks and gowns. Surgical suits and dresses, commonly known as scrub suits, are excluded.(b)
Classification. (1) Class II (special controls) for surgical gowns and surgical masks. A surgical N95 respirator or N95 filtering facepiece respirator is not exempt if it is intended to prevent specific diseases or infections, or it is labeled or otherwise represented as filtering surgical smoke or plumes, filtering specific amounts of viruses or bacteria, reducing the amount of and/or killing viruses, bacteria, or fungi, or affecting allergenicity, or it contains coating technologies unrelated to filtration (e.g., to reduce and or kill microorganisms). Surgical N95 respirators and N95 filtering facepiece respirators are exempt from the premarket notification procedures in subpart E of part 807 of this chapter subject to § 878.9, and the following conditions for exemption:(i) The user contacting components of the device must be demonstrated to be biocompatible.
(ii) Analysis and nonclinical testing must:
(A) Characterize flammability and be demonstrated to be appropriate for the intended environment of use; and
(B) Demonstrate the ability of the device to resist penetration by fluids, such as blood and body fluids, at a velocity consistent with the intended use of the device.
(iii) NIOSH approved under its regulation.
(2) Class I (general controls) for surgical apparel other than surgical gowns and surgical masks. The class I device is exempt from the premarket notification procedures in subpart E of part 807 of this chapter subject to § 878.9.