K Number
K131826
Date Cleared
2013-11-22

(155 days)

Product Code
Regulation Number
880.6250
Reference & Predicate Devices
Predicate For
N/A
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

Powder Free Vinyl Patient Examination Gloves, Clear (non-colored) are disposable devices which made of PVC material ,intended for medical purpose that worn on examiner's hand or finger to prevent contamination between patient and examiner and they meets all of the requirements of ASTM standard D 5250-06 (Reapproved 2011).

Powder Free Vinyl Patient Examination Gloves, Clear (non-colored) is a disposable device intended for medical purposes that is worn on the examiner's hand or finger to prevent contamination between patient and examiner.

Device Description

PVC films form a barrier to body fluids and bloodborne Pathogens. The PVC rubber is water tight under normal conditions of use. It's tensile properties cause it to conform to the hand, allowing movements necessary for a medical procedure. Poly (vinyl chloride) glove is known to create a barrier to bloodborne pathogens and body fluids. ASTM conforming tensile properties create a glove that is strong and flexible. The leaching process removes traces of chemical accelerants that may be chemically irritating. The glove is manufactured in accordance with the requirements of ASTM DS250-06(Reapproved 2011) and ASTM D5151-06(Reapproved 2011) requirements.

AI/ML Overview

The provided text describes the acceptance criteria and performance of Powder Free Vinyl Patient Examination Gloves.

Here's the breakdown of the information requested:

1. A table of acceptance criteria and the reported device performance

CharacteristicsAcceptance Criteria (Standard)Device Performance
DimensionASTM standard D 5250-06 (Reapproved 2011)Meets
Physical PropertiesASTM standard D 5250-06 (Reapproved 2011)Meets
Freedom from Pinholes21 CFR 800.20Meets
Powder ResidualASTM standard D 5250-06 (Reapproved 2011) and D6124-06 (Reapproved 2011)Meets (<2mg/glove)
Biocompatibility (Primary Skin Irritation)Primary Skin Irritation in rabbits ISO 10993-10:2002/Amd.1:2006Passes (Not a Primary Skin Irritation)
Biocompatibility (Dermal Sensitization)Dermal sensitization in the guinea pig ISO 10993-10:2002/Amd.1:2006Passes (Not a Dermal sensitization)
Dimensions (Length)ASTM D5250-06 (Reapproved 2011) ≥230mm min.230mm min for all sizes
Dimensions (Width)ASTM D5250-06 (Reapproved 2011) (Small: 80-90mm, Medium: 90-100mm, Large: 100-110mm, Xlarge: 110-120mm)(Small: 80-85mm, Medium: 95-100mm, Large: 102-108mm, Xlarge: 113-118mm) - Considered Substantially Equivalent
Dimensions (Thickness)ASTM D5250-06 (Reapproved 2011) (Finger: 0.05mm min., Palm: 0.08mm min.)(Finger: 0.09-0.12mm, Palm: 0.09-0.12mm) - Considered Substantially Equivalent
Physical Properties (Elongation)ASTM D 5250-06 (Reapproved 2011) (Before aging/after aging: ≥300%)(Before aging/after aging: 390-420%) - Considered Substantially Equivalent
Physical Properties (Tensile Strength)ASTM D 5250-06 (Reapproved 2011) (Before aging/after aging: ≥14MPa)(Before aging/after aging: 15-20 MPa) - Considered Substantially Equivalent
Freedom from Pinholes (AQL)ASTM D5151-06 (Reapproved 2011)Meets ASTM D5151-06 (Reapproved 2011) - Holes at Inspection Level I AQL2.5
Materials usedPVCPVC
Dusting or Donning PowderPU or Surface Coating AgentPU / Surface Coating Agent

2. Sample size used for the test set and the data provenance (e.g. country of origin of the data, retrospective or prospective)

The document does not explicitly state the specific sample sizes for each test (e.g., number of gloves tested for pinholes, physical properties, or biocompatibility). It references adherence to ASTM and ISO standards, which typically specify sampling plans. The data provenance is not specified, but the manufacturer is based in Jiangsu, China, so it can be inferred that testing was conducted either internally or by laboratories associated with the manufacturer, likely in China. The studies are non-clinical performance tests.

3. Number of experts used to establish the ground truth for the test set and the qualifications of those experts (e.g. radiologist with 10 years of experience)

This information is not applicable. The device is a patient examination glove, and its performance is evaluated against engineering and biological standards (ASTM, ISO, CFR), not against expert clinical judgment for a diagnostic task.

4. Adjudication method (e.g. 2+1, 3+1, none) for the test set

This information is not applicable, as there's no diagnostic judgment involved that would require adjudication. Performance is measured against objective standards.

5. If a multi reader multi case (MRMC) comparative effectiveness study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

This information is not applicable. The device is a physical product (gloves), not an AI-assisted diagnostic tool.

6. If a standalone (i.e. algorithm only without human-in-the loop performance) was done

This information is not applicable. The device is a physical product, not an algorithm.

7. The type of ground truth used (expert consensus, pathology, outcomes data, etc)

The "ground truth" for this device's performance is defined by the requirements of the specified international and national standards:

  • ASTM standard D 5250-06 (Reapproved 2011) for dimensions and physical properties.
  • 21 CFR 800.20 for freedom from pinholes.
  • ASTM standard D 6124-06 (Reapproved 2011) for powder residual.
  • ISO 10993-10:2002/Amd.1:2006 for biocompatibility (skin irritation and sensitization).

These standards provide objective, measurable criteria for the device's performance characteristics.

8. The sample size for the training set

This information is not applicable. The device is a manufactured product, not a machine learning model that requires a training set.

9. How the ground truth for the training set was established

This information is not applicable, as there is no training set for this type of device.

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Section C 510(k) Summary

510(K) Summary

"This summary of 510(k) safety and effectiveness information is being submitted in accordance with the requirements of SMDA 1990 and 21 CFR 807.92."

"The assigned 510(k) number is: _K131826 11

Premarket Notification [510(k)] Summary

1.0 Submitter:

Submitter's name :Jiangsu Toptouch Glove Co., Ltd.
Submitter's address :No.103 Xihu Road, Suqian, Jiangsu, 223800China
Phone number :86-527-88286077
Fax number :86-527-88286077
Name of contact person:Mr.Zhong Miao
Date of preparation :2013-11-12

2.0 Name of the Device

Device Name:Powder Free Vinyl Patient ExaminationGloves, Clear (non-colored)
Proprietary/Trade name:Toptouch
Common Name:Exam gloves
Classification Name:Patient examination glove
Device Classification:I
Regulation Number:21 CFR 880.6250
Panel:General Hospital (80)
Product Code:LYZ

3.0 Predicate device

Device Name:Powder-Free Vinyl Patient Examination Glove(Non-colored)
Company name:Zhang Jia Gang Fengyuan Plastic Product Co.Ltd.
510(K) Number:K091663.

4.0 Device Description:

4.1 How the device functions: PVC films form a barrier to body fluids and bloodborne Pathogens

4.2 Scientific concepts that form the basis for the device

The PVC rubber is water tight under normal conditions of use. It's tensile properties cause it to conform to the hand, allowing movements necessary for a

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medical procedure.

Physical and performance characteristics such as design, materials and 4.3 physical properties:

Poly (vinyl chloride) glove is known to create a barrier to bloodborne pathogens and body fluids. ASTM conforming tensile properties create a glove that is strong and flexible. The leaching process removes traces of chemical accelerants that may be chemically irritating. The glove is manufactured in accordance with the requirements of ASTM DS250-06(Reapproved 2011) and ASTM D5151-06(Reapproved 2011) requirements.

5.0 Device Intended Use (Indication for use):

Powder Free Vinyl Patient Examination Gloves, Clear (non-colored) are disposable devices which made of PVC material ,intended for medical purpose that worn on examiner's hand or finger to prevent contamination between patient and examiner and they meets all of the requirements of ASTM standard D 5250-06 (Reapproved 2011).

Powder Free Vinyl Patient Examination Gloves, Clear (non-colored) is a disposable device intended for medical purposes that is worn on the examiner's hand or finger to prevent contamination between patient and examiner.

6.0 Summary of the Technological Characteristics of the Device:

The Powder Free Vinyl Patient Examination Gloves, Clear (non-colored), non sterile are summarized with the following technological characteristics compared to ASTM or equivalent standard

CharacteristicsStandardDevice performance
DimensionASTM standard D5250-06(Reapproved 2011).Meets
Physical PropertiesASTM standard D5250-06(Reapproved 2011).Meets
Freedom frompinholes21 CFR 800.20Meets
Powder ResidualASTM standard D 5250-06(Reapproved 2011).andD6124-06(Reapproved 2011).Meets<2mg/glove
BiocompatabilityPrimary Skin Irritation in rabbitsISO 10993-10:2002/Amd.1:2006PassesNot a Primary SkinIrritation
Dermal sensitization in theguinea pigISO 10993-10: 2002/Amd.1:2006PassesNot a Dermalsensitization

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7.0 Substantial Equivalent Based on Assessment of Non-Clinical Performance Data:

Powder Free Vinyl Patient Examination Gloves, Clear (non-colored), meet D5250-06 (Reapproved 2011), per ASTM requirements per ASTM D6124-06(Reapproved 2011), per 21 CFR 800.20 and ISO 10993-10: 2002/Amd. 1 :2006.

The performance test data of the non clinical tests that support a determination of substantial equivalent is the same as mentioned immediately above.

8.0 Substantial Equivalent Based on Assessment of Clinical Performance Data:

Clinical data is not needed for gloves or for most devices cleared by the 510(k) process.

Featuresજ્DescriptionPredicate DeviceSubject DeviceResult of Comparison
CompanyZhang Jia Gang FengyuanJiangsu Toptouch Glove Co.,
Plastic Product Co.Ltd.Ltd.
510(K) NumberK091663--
Product namePowder Free Vinyl PatientPowder Free Vinyl Patientsame
Examination Gloves, ClearExamination Gloves, Clear
(Non-colored)(non-colored)
Product CodeLYZLYZsame
SizeSmall/ Medium/Small/ Medium/same
Large/X largeLarge/X large
Intend for usePowder free Vinyl PatientPowderfreeVinylPatientSubstantially equivalent
Examination Gloves,Examination Gloves, Clear
Clear(Non-colored)is a(Non-colored) is a disposable
disposable device intendeddevice intendedfor medical
for medical purposes that ispurposes that is worn on the
worn on the examiner's handexaminer's hand or finger to
or finger to preventprevent contamination between
contamination betweenpatient and examiner.
patient and examiner.
DeviceMeets ASTM D5250-06Meets ASTMSubstantially equivalent
Description and(Reapproved 2011)D5250-06
Specifications(Reapproved 2011)
DimensionsMeets ASTM230mm min for all sizesSubstantially equivalent
-- LengthD5250 -06
(Reapproved 2011)
≥230mm min
DimensionsMeets ASTM D5250-06Substantially equivalent
-- Width(Reapproved 2011)
80-90 mmSmallSmall80-85 mm
90-100mmMedium95-100mmMedium
100-110mmLarge102-108mmLarge
Xlarge110-120 mm113-118 mmX large
Dimensions--ThicknessMeets ASTM D5250-06(Reapproved 2011)Finger 0.05mm min.Palm 0.08mm min.Thickness (mm) min.Finger 0.09-0.12Palm 0.09-0.12Substantially equivalent
PhysicalPropertiesMeets ASTM D 5250-06(Reapproved 2011)Before aging/after agingElongation ≥300%Tensile Strength≥ 14MPaBefore aging/after agingElongation :390-420%Tensile Strength: 15-20 MPaSubstantially equivalent
Freedom fromPinholesMeets• 21 CFR 800.20• ASTM D5250-06(Reapproved 2011)• ASTM D 5151-06(Reapproved 2011)Meets ASTMD5151-06(Reapproved 2011)Holes atInspection Level IAQL2.5Substantially equivalent
ResidualPowderMeets ASTMD 6124-06(Reapproved 2011)below 2mg of residualpowderMeets ASTMD 6124-06(Reapproved 2011)Results generated values below2mg of residual powderSubstantially equivalent
Materials usedto fabricate thedevicesPVCPVCSubstantially equivalent
Dusting orDonningPowder:PUPUSubstantially equivalent
Dusting orDonningPowder: namePUSurface Coating AgentSubstantially equivalent
Compareperformancedata supportingsubstantialequivalenceMeetsASTM D5151-06(Reapproved 2011)ASTM D5250-06(Reapproved 2011)ASTM D6124-06(Reapproved 2011)MeetsASTM D5151-06(Reapproved 2011)ASTM D5250-06(Reapproved 2011)ASTM D6124-06(Reapproved 2011)Substantially equivalent
Single Patient UseSingle Patient UseSingle Patient UseSubstantially equivalent
BiocompatibilitySKIN IRRITATIONDERMAL andSENSITIZATIONSTUDIES Meets ISO10993-10:2002/Amd.1:2006The test article was anon-irritant and non-sensitizer.SKIN IRRITATION DERMALand SENSITIZATIONSTUDIES Meets ISO10993-10:2002/Amd.1:2006Substantially equivalent
Labeling for thelegally marketeddevice to whichsubstantialequivalence isclaimed.-Powder Free-Patient Examination Glove-Single Use Only- Manufactured For:- Lot-Powder Free-Patient Examination Glove-Single Use Only- Manufactured For:- LotSubstantially equivalent

9.0 Substantial Equivalence Comparison:

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10.0 Substantial Equivalence Comparison:

It can be concluded that the Powder Free Vinyl Patient Examination Gloves, Clear (non-colored) meet the ASTM standard or equivalent standard and FDA requirements for waterleak test on pinhole AQL., meet labeling claims.

It can be concluded that the Powder Free Vinyl Patient Examination Gloves, Clear (non-colored) is as safe, as effective, and performs as well as the predicate device, Powder-Free Vinyl Patient Examination Glove (Non-colored) Zhang Jia Gang Fengyuan Plastic Product Co., Ltd. K091663.

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DEPARTMENT OF HEALTH & HUMAN SERVICES

Image /page/5/Picture/1 description: The image shows the logo for the U.S. Department of Health & Human Services. The logo features a stylized caduceus, a symbol often associated with medicine and healthcare. The words "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" are arranged in a circular pattern around the caduceus.

Food and Drug Administration 10903 New Hampshire Avenue Document Control Center - WO66-G609 Silver Spring, MD 20993-0002

November 22, 2013

Jiangsu Toptouch Glove Company C/O Chu Xiaoan Beijing Easy-Link Company, Limited Room 1606 Building 1 Jian Xiang Yuan Number 209 Bei Si Huan Zhong Road Haidan District CHINA 100083

Re: K131826

Trade/Device Name: Powder Free Vinyl Patient Examination Gloves, Clear (non-colored) Regulation Number: 21 CFR 880.6250 Regulation Name: Patient Examination Glove Regulatory Class: I Product Code: LYZ Dated: October 14, 2013 Received: October 24, 2013

Dear Mr. Xiaoan:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration. listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you, however, that device labeling must be truthful and not misleading.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

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Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); medical device reporting (reporting of medical device-related adverse events) (21 CFR 803); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Division of Small Manufacturers, International and Consumer Assistance at its tollfree number (800) 638-2041 or (301) 796-7100 or at its Internet address

http://www.fda.gov/MedicalDevices/ResourcesforYou/Industry/default.htm. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to

http://www.fda.gov/MedicalDevices/Safety/ReportaProblem/default.htm for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance.

You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 796-7100 or at its Internet address

http://www.fda.gov/MedicalDevices/Resourcesfor You/Industry/default.htm.

Sincerely yours,

Image /page/6/Picture/8 description: The image shows a logo with the text "Tejashri Purohit-Sheth, M.D. Clinical Deputy Director DAGRID FOR". The logo is stylized with overlapping lines and geometric shapes. The text is arranged in a way that it is partially obscured by the logo's design. The word "FOR" is located at the bottom right of the image.

Erin Keith, M.S. Division Director, Acting Division of Anesthesia, General Hospital, Respiratory, Infection Control, and Dental Devices Office of Device Evaluation Center for Devices and Radiological Health

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DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration

Indications for Use

510(k) Number (if known) K131826

Device Name

Powder Free Vinyl Patient Examination Gloves, Clear (non-colored)

Indications for Use (Describe)

Powder Free Vinyl Patient Examination Gloved) is a non-sterile disposable device intended for medical purposes that is worn on the examiner's hand or finger to prevent contamination between patient and examiner.

Type of Use (Select one or both, as applicable)

_ Prescription Use (Part 21 CFR 801 Subpart D)

[x] Over-The-Counter Use (21 CFR 801 Subpart C)

PLEASE DO NOT WRITE BELOW THIS LINE - CONTINUE ON A SEPARATE PAGE IF NEEDED.

FOR FOR FDA USE ONLY Concurrence of Center for Devices and Radiological Health (CDRH) (Signature)

Image /page/7/Picture/12 description: The image shows a signature and date. The signature is "Elizabeth F. Claverie -S". The date is "2013.11.22 10:38:05'00'". There is also a logo in the image.

Form Approved: OMB No. 0910-0120 Expiration Date: December 31, 2013 See PRA Statement on last page.

§ 880.6250 Non-powdered patient examination glove.

(a)
Identification. A non-powdered patient examination glove is a disposable device intended for medical purposes that is worn on the examiner's hand or finger to prevent contamination between patient and examiner. A non-powdered patient examination glove does not incorporate powder for purposes other than manufacturing. The final finished glove includes only residual powder from manufacturing.(b)
Classification. Class I (general controls). The device, when it is a finger cot, is exempt from the premarket notification procedures in subpart E of part 807 of this chapter subject to the limitations in § 880.9.