K Number
K090100
Device Name
SOFTSEAL-STF
Manufacturer
Date Cleared
2009-03-11

(55 days)

Product Code
Regulation Number
N/A
Reference & Predicate Devices
N/A
Predicate For
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

SoftSeal-STF is indicated for use in the management of bleeding wounds such as skin lacerations, vascular access sites, or percutaneous catheter or tube sites. SoftSeal promotes the rapid control of bleeding for patients on hemodialysis and patients on anticoagulation therapy.

Device Description

SoftSeal-STF is a sterile topical pad, packaged in a foil pouch, and sterilized with gamma irradiation to a SAL of 10-6.

AI/ML Overview

I am sorry, but the provided text does not contain the information required to answer your request. The document is an FDA 510(k) clearance letter and summary for a medical device (SoftSeal-STF topical hemostasis pad). While it mentions the device's intended use and technological characteristics, it does not include any details about acceptance criteria or a specific study proving the device meets said criteria.

The document primarily focuses on regulatory approval based on substantial equivalence to a predicate device, rather than detailed performance study results against predefined acceptance criteria.

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Image /page/0/Picture/0 description: The image shows the logos of the Department of Health & Human Services and the U.S. Food & Drug Administration (FDA). The Department of Health & Human Services logo is on the left, and the FDA logo is on the right. The FDA logo is a blue square with the letters "FDA" in white, followed by the words "U.S. FOOD & DRUG ADMINISTRATION" in blue.

Chitogen, Inc. c/o Janna Bereuter Director, Clinical & Regulatory Affairs 7255 Ohms Lane Minneapolis, Minnesota 55439

July 28, 2023

Re: K090100 Trade/Device Name: SoftSeal-STF Regulatory Class: Unclassified Product Code: QSY, LYA

Dear Janna Bereuter:

The Food and Drug Administration (FDA) is sending this letter to notify you of an administrative change related to your previous substantial equivalence (SE) determination letter dated March 11, 2009. Specifically, FDA is updating this SE Letter because FDA has better categorized your device technology under product codes QSY and LYA.

Please note that the 510(k) submission was not re-reviewed. For questions regarding this letter please contact Julie Morabito, OHT4: Office of Surgical and Infection Control Devices, 240-402-3839, Julie.Morabito@fda.hhs.gov.

Sincerely,

Julie A. Morabito -S

Julie Morabito, Ph.D. Assistant Director DHT4B: Division of Infection Control and Plastic Surgery Devices OHT4: Office of Surgical and Infection Control Devices Office of Product Evaluation and Quality Center for Devices and Radiological Health

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DEPARTMENT OF HEALTH & HUMAN SERVICES

Image /page/1/Picture/1 description: The image shows the seal for the Department of Health & Human Services. The seal is circular and contains the words "DEPARTMENT OF HEALTH & HUMAN SERVICES . USA" around the perimeter. In the center of the seal is an image of an eagle.

MAR 1 1 2009

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

Chitogen, Inc. % Ms. Janna Bereuter Director, Clinical and Regulatory Affairs 7255 Ohms Lane Minneapolis, Minnesota 55439

Re: K090100 Trade/Device Name: SoftSeal-STF Regulatory Class: Unclassified Product Code: FRO Dated: January 12, 2009 Received: January 29, 2009

Dear Ms. Bereuter:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

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Page 2 - Ms. Janna Bereuter

This letter will allow you to begin marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Center for Devices and Radiological Health's (CDRH's) Office of Compliance at (240) 276-0115. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding postmarket surveillance, please contact CDRH's Office of Surveillance and Biometric's (OSB's) Division of Postmarket Surveillance at (240) 276-3474. For questions regarding the reporting of device adverse events (Medical Device Reporting (MDR)), please contact the Division of Surveillance Systems at (240) 276-3464. You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (240) 276-3150 or at its Internet address http://www.fda.gov/cdrh/industry/support/index.html.

Sincerely yours.

L.A. Ahmed. for.

Mark N. Melkerson Director Division of General, Restorative and Neurological Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

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Indications for Use

K090100 510(k) Number (if known):

Device Name: SoftSeal-STF

Indications for Use:

SoftSeal-STF is indicated for use in the management of bleeding wounds such as skin lacerations, vascular access sites, or percutaneous catheter or tube sites. SoftSeal promotes the rapid control of bleeding for patients on hemodialysis and patients on anticoagulation therapy.

Over-The-Counter Use Prescription Use X AND/OR (Part 21 CFR 801 Subpart D) (21 CFR 801 Subpart C) (PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE OF NEEDED)

Concurrence of CDRH, Office of Device Evaluation (ODE)

Daniel Kraune for MXWM 3/10/2009

(Division Sign-Off) Division of General, Restorative, and Neurological Devices

Page _ of _

§510(k) Number K090100

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510(k) Summary

K090100

page 1/2

MAR 1 1 2009

Submitted by:Chitogen Inc.7255 Ohms LaneMinneapolis, MN 55439Phone: (952) 229-8899Fax: (952) 229-8898
Contact Person:Janna Bereuter
Date Prepared:15 December 2008
Proprietary Name:Chitogen Inc. SoftSeal-STF
Common Name:Topical Hemostasis Pad
Classification:Unclassified
Classification Name:Topical Wound Dressing Pad
Product Code:FRO
Predicate Device:Scion Cardio-Vascular Clo-Sur P.A.D K-032986
Device Description:SoftSeal-STF is a sterile topical pad, packaged in a foil pouch, and sterilized with gamma irradiation to a SAL of 10-6.
Intended Use:The SoftSeal-STF pad made by Chitogen Inc. is intended for the local management of topical bleeding wounds, the rapid control of bleeding in patients following hemo-dialysis, or in patients on anticoagulation therapy. The dressing is indicated for the following wounds: lacerations, abrasions, nose bleeds, and the skin surface puncture sites resulting from vascular access procedures, percutaneous catheters or tubes.

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510(k) Summary

Technological Characteristics:

The Chitogen Inc., SoftSeal-STF pad is a non-woven pad made of a proprietary formulation of poly-D-glucosamine and poly-N- acety|glucosamine derived from chitosan. The natural biological property of this material gives the SoftSeal pad an advantage as an effective bacterial barrier while providing for an optimal wound-healing environment. Several biomedical applications of poly-D-glucosamine and poly-Nacetylglucosamine have been reported. The studies represent research on the safety and use of these materials, published over a period of decades by scientists from around the world. This large body of scientific literature satisfies the requirement that a general recognition of safety requires common knowledge about the substance throughout the scientific community. This formulation has many useful and advantageous properties in their application as a wound dressing, namely biocompatibility, biodegradability, hemostatic activity, anti-infectional activity. The technological characteristics of the SoftSeal-STF pad are the same as the predicate device (Scion Cardio-Vascular, Inc., Clo-Sur PAD ). The Chitogen SoftSeal-STF pad works in the same manner as the approved predicate device.

KO90100

N/A