K Number
K023013

Validate with FDA (Live)

Manufacturer
Date Cleared
2003-02-26

(169 days)

Product Code
Regulation Number
888.3040
Reference & Predicate Devices
Predicate For
AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
Intended Use

The Stryker XCEL Anchor is intended for use in securing soft tissue to bone in such procedures as:
Shoulder: Bankart repair, SLAP lesion repair, Rotator cuff repair, Capsular shift repair, Biceps tenodesis, Acromio-clavicular separation
Elbow: Biceps tendon reattachment
Foot & Ankle: Achilles tendon repair/reconstruction, Lateral stabilization, Medial stabilization
Knee: Medial collateral ligament repair, Lateral collateral ligament repair, Joint capsule closure to anterior proximal tibia, Posterior oblique ligament or joint capsule to tibia repair, Extra capsular reconstruction/ITB tenodesis, Patellar ligament and tendon avulsion repairs
The Stryker XCEL Anchor is intended for single-use only.

Device Description

The Stryker XCEL Anchor System consists of a Poly L-lactic acid (PLLA) anchor pre-threaded with nonabsorbable, braided polyester surgical suture, and pre-assembled on a disposable inserter. Stryker instrumentation, drill and soft-tissue guide/drill guide, will be used to install the Stryker XCEL Anchor. The Stryker XCEL Anchor System will be provided pre-assembled, sterile for single-use applications (ASTM 4169). The device will be sterilized by Ethylene oxide (EN550), including limits for Ethylene Oxide residuals and validated to a sterility assurance level (SAL) of 10th. The device is biocompatible per ISO 10993 and G95-1.

AI/ML Overview

The provided text is a 510(k) premarket notification summary and a letter from the FDA regarding the Stryker XCEL Anchor System. This document does not contain the kind of detailed information requested about acceptance criteria and a study proving a device meets them, especially in the context of AI/ML performance (e.g., sample sizes for test/training sets, expert consensus, MRMC studies).

Instead, it describes a medical device (Stryker XCEL Anchor System) for securing soft tissue to bone and states its substantial equivalence to a predicate device (Mitek Panalok 3.5mm Absorbable Anchor System). The safety and effectiveness are established by demonstrating this substantial equivalence, not through a performance study against specific acceptance criteria as you've outlined for AI/ML devices.

Therefore, I cannot extract the requested information from this document. The document primarily focuses on:

  • Device Name and Classification: Stryker XCEL Anchor System, Class II, Smooth or Threaded Metallic Bone Fixation Fasteners.
  • Predicate Device: Mitek Panalok 3.5mm Absorbable Anchor System.
  • Intended Use: Securing soft tissue to bone.
  • Device Description: Poly L-lactic acid (PLLA) anchor with non-absorbable, braided polyester surgical suture, pre-assembled on a disposable inserter.
  • Substantial Equivalence: Claimed based on intended use, safety, efficacy, and performance compared to the predicate device.
  • Sterilization and Biocompatibility: Information provided (Ethylene oxide, ISO 10993).
  • Indications for Use: Specific surgical procedures (e.g., Bankart repair, rotator cuff repair, Achilles tendon repair).

There is no mention of:

  • Acceptance criteria in the form of performance metrics (like sensitivity, specificity, F-score, etc.).
  • A specific "study" with test sets, training sets, ground truth establishment, expert readers, or AI/ML components.
  • Multi-reader multi-case (MRMC) comparative effectiveness studies or standalone algorithm performance.

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Image /page/0/Picture/0 description: The image shows the logo for Stryker Endoscopy. The word "Stryker" is in a bold, sans-serif font, with the "S" stylized to look like a medical symbol. The word "Endoscopy" is in a smaller, sans-serif font and is located below the word "Stryker". There is a registered trademark symbol to the right of the word "Stryker".

K0230/3

Page 11

FEB 2 6 2003

SUMMARY OF SAFETY AND EFFECTIVENESS

De ice Name

Classification Name:

Common and Usual Name: Proprietary Name:

Smooth or Threaded Metallic Bone Fixation Fasteners: 21 CFR §888.3040, Class II Suture Anchor (MAI) Stryker XCEL Anchor System

Prodicate Device

Mi ek Panalok 3.5mm Absorbable Anchor System, (#K970896), currently marketed by Mitek Prc ducts/lithicon (Westwood, MA).

Su nmarv

Th s summary of 510(k) safety and effectiveness is being submitted in accordance with requirements of SMDA 1990.

Th > Stryker XCEL Anchor System is intended to be implanted within a pre-drilled bone hole site and pr vide a means for firmly securing soft tissue to bone using suture. The use of suture anchors is common in >rthopedic surgery, and has been well published in professional journals such as Arthroscopy: The Jo irnal of Arthroscopic and Related Surgery.

The Stryker XCEL Anchor System consists of a Poly L-lactic acid (PLLA) anchor pre-threaded with nonab torbable, braided polyester surgical suture, and pre-assembled on a disposable inserter. Stryker in: trumentation, drill and soft-tissue guide/drill guide, will be used to install the Stryker XCEL Anchor.

The Stryker XCEL Anchor System will be provided pre-assembled, sterile for single-use applications (ASTM 4169). The device will be sterilized by Ethylene oxide (EN550), including limits for Ethylene O: ide residuals and validated to a sterility assurance level (SAL) of 10th. The device is biocompatible per IS 3-10993 and G95-1. The Stryker XCEL Anchor is substantially equivalent in intended use, safety, and ef icacy to the predicate device. The subject device was shown to have substantially equivalent performance when compared to the predicate device.

Tl e Stryker XCEL Anchor System is considered substantially equivalent to the Mitek Panalok 3.5mm A' sorbable Anchor System.

Contact:

Date: December 11, 2002

Alisa Miller Senior Quality Engineer Stryker Endoscopy 5900 Optical Court San Jose, CA 95138 (408) 754-2000 x.2259

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Image /page/1/Picture/1 description: The image is a black and white logo for the U.S. Department of Health & Human Services. The logo features a stylized image of an eagle with three lines representing its wings and head. The words "DEPARTMENT OF HEALTH & HUMAN SERVICES - USA" are arranged in a circular pattern around the eagle.

Public Health Service

FEB 2 6 2003

Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850

Ms. Alisa Miller Senior Quality Engineer Stryker Endoscopy 5900 Optical Court San Jose, California 95138

Re: K023013

Trade/Device Name: Stryker XCEL Anchor System Regulation Number: 21 CFR 888.3040 Regulation Name: Smooth or threaded metallic fixation fastener Regulatory Class: II Product Code: HWC Dated: December 11, 2002 Received: December 12, 2002

Dear Ms. Miller:

We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration.

If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050.

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Page 2 - Ms. Alisa Miller

This letter will allow you to begin marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market.

If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Office of Compliance at (301) 594-4639. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97) you may obtain. Other general information on your responsibilities under the Act may be obtained from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 443-6597 or at its Internet address http://www.fda.gov/cdrh/dsma/dsmamain.html

Sincerely yours,

Mark N. Millman

Celia M. Witten, Ph.D., M.D. Director Division of General, Restorative and Neurological Devices Office of Device Evaluation Center for Devices and Radiological Health

Enclosure

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De zember 11, 2002

510(k) Number: K023013

INDICATION FOR USE:

The Stryker XCEL Anchor is intended for use in securing soft tissue to bone in such procedures as:

Shoulder:Elbow:Foot & Ankle:
Bankart repairBiceps tendon reattachmentAchilles tendon repair/reconstruction
SI AP lesion repairLateral stabilization
Rotator cuff repairMedial stabilization
Capsular shift repair
Biceps tenodesis
Acromio-clavicular separation

Knee:

Medial collateral ligament repair La teral collateral ligament repair Joint carsule closure to anterior proximal tibia P sterior oblique ligament or joint capsule to tibia repair Extra capsular reconstruction/ITB tenodesis P: tellar ligament and tendon avulsion repairs

The Stryker XCEL Anchor is intended for single-use only.

PLEASE DO NOT WRITE BELOW THIS LINE-CONTINUE ON ANOTHER PAGE IF NEEDED

Concurrence of CDRH, Office of Device Evaluation (ODF)

Mark M
(Division Sign-Off)

Division of General, Restorative and Neurological Devices

Number K023013

Over-the-Counter Use No

Prescription Use (Fer 21 CFR 801.109)

OR

§ 888.3040 Smooth or threaded metallic bone fixation fastener.

(a)
Identification. A smooth or threaded metallic bone fixation fastener is a device intended to be implanted that consists of a stiff wire segment or rod made of alloys, such as cobalt-chromium-molybdenum and stainless steel, and that may be smooth on the outside, fully or partially threaded, straight or U-shaped; and may be either blunt pointed, sharp pointed, or have a formed, slotted head on the end. It may be used for fixation of bone fractures, for bone reconstructions, as a guide pin for insertion of other implants, or it may be implanted through the skin so that a pulling force (traction) may be applied to the skeletal system.(b)
Classification. Class II.