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510(k) Data Aggregation

    K Number
    K222720

    Validate with FDA (Live)

    Date Cleared
    2022-12-03

    (86 days)

    Product Code
    Regulation Number
    880.6250
    Reference & Predicate Devices
    Predicate For
    N/A
    AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
    Intended Use

    A nitrile patient examination glove is a disposable device made of nitrile rubber intended for medical purposes that is worn on the examiner's hand or finger to prevent contamination between patient and examiner

    Device Description

    Blue Nitrile Powder-Free Patient Examination Glove, Non-Sterile is manufactured from nitrile rubber. Innersurface of gloves undergoes surface treatment process to produce a smooth surface that assists the user in donning the gloves without using any lubricant such as powder or silicone on the glove surface. The glove is ambidextrous, i.e., can be worn on right or left hand.

    AI/ML Overview

    Based on the provided document, the device in question is a Blue Nitrile Powder-Free Patient Examination Glove, Non-Sterile. This is not a medical imaging AI device or a diagnostic AI device. The document is a 510(k) Premarket Notification summary for a medical glove, which is a physical device, and the testing conducted is for physical and chemical properties, not algorithmic performance.

    Therefore, the requested information, which pertains to the acceptance criteria and study designs for AI/ML device performance (e.g., sample size for test set, expert ground truth, MRMC studies, standalone performance, training set details), is not applicable to this document.

    The document describes non-clinical testing for the glove, focusing on properties like tensile strength, elongation, dimensions, watertight integrity, residual powder, and biocompatibility.

    However, I can extract and present the acceptance criteria and performance data as per the document's content, formatted as a table, making it clear that this applies to a physical device and not an AI/ML system.


    Acceptance Criteria and Device Performance for Blue Nitrile Powder-Free Patient Examination Glove, Non-Sterile (K222720)

    The following table summarizes the non-clinical acceptance criteria and the reported performance of the device. It's crucial to understand that this concerns the physical and chemical properties of a medical glove, not the performance of an AI/ML algorithm.

    1. Table of Acceptance Criteria and Reported Device Performance

    CharacteristicStandard / Test MethodAcceptance CriteriaReported Device PerformanceStatus
    Physical Properties
    Tensile StrengthASTM D412Before Aging: Min 14.0 MPaBefore Aging: XS - 28.1 MPa, S - 28.4 MPa, M - 29.2 MPa, L - 28.0 MPa, XL - 28.9 MPaPass
    After Aging: Min 14.0 MPaAfter Aging: XS - 31.2 MPa, S - 30.9 MPa, M - 32.3 MPa, L - 31.0 MPa, XL - 31.3 MPaPass
    Ultimate ElongationASTM D412Before Aging: Min 500%Before Aging: XS - 540%, S - 530%, M - 550%, L - 540%, XL - 540%Pass
    After Aging: Min 400%After Aging: XS - 460%, S - 460%, M - 470%, L - 490%, XL - 480%Pass
    DimensionsASTM D3767
    Length (all sizes)Min 240 mmXS - 244 mm, S - 242 mm, M - 242 mm, L - 243 mm, XL - 244 mmPass
    WidthXS: $70 \pm 10$ mm; S: $80 \pm 10$ mm; M: $95 \pm 10$ mm; L: $110 \pm 10$ mm; XL: $120 \pm 10$ mmXS - 74.0 mm, S - 85.0 mm, M - 95.0 mm, L - 106 mm, XL - 115 mmPass
    Thickness (Finger)Min 0.05 mmAll sizes (XS, S, M, L, XL) - 0.10 mmPass
    Thickness (Palm)Min 0.05 mmAll sizes (XS, S, M, L, XL) - 0.06 mmPass
    Watertight IntegrityASTM D5151AQL 1.5, Acceptance No. 10 (for sample size 315 pcs)For sample size 315 pcs (batch size 150,001 to 500,000): XS - 4 leaks, S - 2 leaks, M - 3 leaks, L - 1 leak, XL - 2 leaks. All within acceptance criteria.Pass
    Residual PowderASTM D6124Less than 2 mg per glove (<2mg/glove)XS - 0.30 mg/glove, S - 0.26 mg/glove, M - 0.34 mg/glove, L - 0.38 mg/glove, XL - 0.40 mg/glove. All are below 2 mg/glove.Pass
    BiocompatibilityISO 10993-10, 16 CFR Part 1500Not an irritantThe test material did not cause an irritant response. Primary Irritant Response Category deemed 'Negligible'.Same
    Primary Skin IrritationISO 10993-10, 16 CFR Part 1500Not a sensitizerThe test material did not produce a skin sensitization effect in guinea pigs.Same
    Dermal SensitizationISO 10993-11Device extracts do not pose a systemic toxicity concernThe test item did not induce any systemic toxicity in Swiss albino mice.Same
    Acute Systemic Toxicity

    Regarding the AI/ML specific questions (2-9):

    The device is a non-AI medical product (patient examination glove). Therefore, the concepts and requirements typically associated with AI/ML device evaluations (such as sample size for AI test and training sets, data provenance, expert ground truth, MRMC studies, standalone performance, etc.) are not applicable to this 510(k) submission. No AI or machine learning components are mentioned or implied in the document for this device. The testing conducted is traditional non-clinical performance testing for a physical product.

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