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510(k) Data Aggregation

    K Number
    K202745
    Date Cleared
    2021-08-23

    (339 days)

    Product Code
    Regulation Number
    878.4040
    Reference & Predicate Devices
    Predicate For
    AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
    Intended Use

    The Disposable medical face mask is intended to be worn to protect both the patient and healthcare personnel from transfer of microorganisms, body fluids and particulate material. The face mask is intended for use in infection control practices to reduce the potential exposure to blood and body fluids. This is a single use, disposable device(s), provided non sterile.

    Device Description

    The disposable medical face mask is single use, three-layer, flat-pleated style with ear loops and nose piece. The mask is manufactured with three layers, the inner and outer layers are made of nonwoven fabrics, and the middle layer is made of melt blown fabrics. The ear loops are held in place over the users' mouth and nose by two elastic ear loops welded to the facemask. The elastic ear loops are not made with natural rubber latex. The nose piece in the layers of facemask is to allow the user to fit the facemask around their nose, which is made of galvanized iron wire. The disposable medical face mask will be provided in blue. The masks are sold non-sterile and are intended to be single use, disposable devices.

    AI/ML Overview

    The provided document describes the acceptance criteria and the study conducted for a Disposable Medical Face Mask (K202745), not an AI-powered medical device. Therefore, many of the requested fields related to AI/MRMC studies, number of experts, and ground truth establishment are not applicable.

    However, I can extract the information relevant to the performance testing of the medical face mask as described in the document.

    Here's a breakdown of the acceptance criteria and study results for the Disposable Medical Face Mask:

    1. Table of Acceptance Criteria and Reported Device Performance

    Test ItemPurposeAcceptance Criteria (Level 2, ASTM F2100-19)Reported Device Performance
    Bacterial filtration efficiency (BFE) (%)To evaluate Bacterial filtration efficiency (BFE) (%)≥98Pass
    Differential pressure (mmH2O/cm²)To evaluate Differential pressure (mmH2O/cm²)<6.0 mmH2O/cm²Pass
    Sub-micron particulate filtration efficiency at 0.1 micron, % (PFE)To evaluate Sub-micron particulate filtration efficiency at 0.1 micron, % (PFE)≥98Pass
    Resistance to penetration by synthetic blood, Minimum pressure in mmHg for pass resultTo evaluate Resistance to penetration by synthetic blood, Minimum pressure in mmHg for pass result29 of 32 test articles passed at 120mmHgPass
    Flame spreadNot explicitly stated purpose in the document, but standard testing for medical masks.Class 1Pass

    Biocompatibility Testing:

    ItemPurposeAcceptance CriteriaReported Device Performance
    CytotoxicityTo evaluate cytotoxicityNoncytotoxicPass (device is noncytotoxic)
    IrritationTo evaluate irritationNonirritatingPass (device is nonirritating)
    SensitizationTo evaluate sensitizationNonsensitizingPass (device is nonsensitizing)

    2. Sample Size Used for the Test Set and Data Provenance

    • Sample Size for Performance Testing: Three nonconsecutive lots were tested, with each lot having 32 samples, for a total of 96 samples.
    • Data Provenance: The document does not explicitly state the country of origin of the data beyond the manufacturer being in China. The testing was described as conforming to recognized standards like ASTM F2100-19 and FDA guidance. The studies are retrospective in the sense that they are conducted on manufactured samples to demonstrate compliance.

    3. Number of Experts Used to Establish the Ground Truth for the Test Set and Qualifications of Those Experts

    • Not Applicable. This is a physical product (face mask) with performance measured against established physical and chemical standards (e.g., filtration efficiency, pressure differential, blood penetration). It does not involve human expert interpretation for "ground truth" in the way an AI diagnostic device would.

    4. Adjudication Method for the Test Set

    • Not Applicable. As mentioned above, the tests are objective measurements against defined standards, not subjective interpretations requiring adjudication.

    5. If a Multi-Reader Multi-Case (MRMC) Comparative Effectiveness Study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

    • Not Applicable. This device is a disposable medical face mask, not an AI-powered diagnostic tool. No MRMC study was performed.

    6. If a Standalone (i.e. algorithm only without human-in-the-loop performance) was done

    • Not Applicable. This is a physical product, not an algorithm.

    7. The type of ground truth used (expert consensus, pathology, outcomes data, etc.)

    • The "ground truth" for this device's performance is based on pre-defined, objective, and standardized laboratory test methods (e.g., those referenced in ASTM F2100-19) and their corresponding quantitative or qualitative pass/fail criteria. These standards are established through expert consensus in the field of material science and medical device testing, but not for case-by-case "ground truth" establishment as in diagnostic imaging.

    8. The sample size for the training set

    • Not Applicable. This refers to a manufactured physical product; there is no "training set" in the context of an algorithmic device.

    9. How the ground truth for the training set was established

    • Not Applicable. As above, there is no training set for this type of device.
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