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510(k) Data Aggregation

    K Number
    K150434
    Device Name
    Injection Needle
    Date Cleared
    2015-06-02

    (103 days)

    Product Code
    Regulation Number
    876.1500
    Reference & Predicate Devices
    Predicate For
    AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
    Intended Use

    The injection needle is to be used in conjunction with an endoscope to perform endoscopic injections, such as for the treatment of esophageal and gastric varies and for submucosal dye marking in the GI tract.

    Device Description

    The injection needle consists of a stainless steel needle attached to plastic tubing and luer lock hub where a standard syringe can be attached for injection of materials through the lumen of the needle into tissue. The minimum required working channel for this proposed product is 2.8mm.

    The proposed products are intended for single use, an individual device is packed in a sealed pouch following ETO sterilization. The device is used for local injection via endoscope, with the average contact time of the product and the mucosa of the human digestive tract of less than 1 hour.

    AI/ML Overview

    The provided document is a 510(k) summary for a medical device (Injection Needle) seeking FDA clearance based on substantial equivalence to a predicate device. It does not contain information about a study proving the device meets specific acceptance criteria in the way an AI/ML medical device would be evaluated. Instead, it focuses on demonstrating equivalence to another marketed device through comparative tables and testing that confirms safety and performance for its intended use.

    Therefore, the requested information elements related to AI device evaluation (test sets, ground truth, expert adjudication, MRMC studies, standalone performance, training sets) are not applicable to this document.

    However, I can extract the acceptance criteria and performance data that are present, related to the device's technical characteristics and performance based on engineering and biocompatibility testing.

    Here's a breakdown of the information that can be extracted from the provided text, and an explanation of why other requested elements are not present:


    Acceptance Criteria and Device Performance (Based on Technical Characteristics and General Performance Testing)

    Acceptance Criteria CategorySpecific Criteria (Implicit in "Same" or "Similar")Reported Device Performance (Proposed Device)Study/Testing that Proves Acceptance (Mentioned)
    Regulatory InformationIdentical Product Code (FBK)FBK510(k) Submission, Comparative Table
    Identical Regulation No. (876.1500)876.1500510(k) Submission, Comparative Table
    Identical Regulatory Class (II)II510(k) Submission, Comparative Table
    SterilitySupplied SterileYesSterilization validation testing
    Individual device packed in sealed pouchYesSterilization validation testing, Packaging details
    EO sterilizationYesSterilization validation testing, Packaging details
    Dimensions (Outer Sheath)Identical Outer Sheath diameter (2.3 mm)2.3 mmPerformance testing, Comparative Table
    Dimensions (Needle Size)Range of needle gauges (19, 22, 25 gauge)19 gauge, 22 gauge, 25 gaugePerformance testing, Comparative Table
    Dimensions (Needle Length)Range of needle lengths (4, 5, 6 mm)4mm, 5mm, 6mmPerformance testing, Comparative Table
    Dimensions (Working Length)Range of working lengths (1800mm, 2000mm, 2300mm)1800mm, 2000mm, 2300mmPerformance testing, Comparative Table
    MaterialsOuter Sheath Material (Thermoplastic-PTFE Polymer)Thermoplastic-PTFE PolymerPerformance testing, Biocompatibility testing, Comparative Table
    Intended UseEndoscopic injections in GI tract"The injection needle is to be used in conjunction with an endoscope to perform endoscopic injections, such as for the treatment of esophageal and gastric varies and for submucosal dye marking in the GI tract."Indications for Use statement, Comparative Table
    ConfigurationNeedle, inner sheath, outer shell, outer sheath, luer lockNeedle, inner sheath, outer shell, outer sheath and luer lockPerformance testing, Comparative Table
    Single UseSingle Use DeviceYesDevice description, Comparative Table
    BiocompatibilityBiocompatible for intended use(Implied by Biocompatibility testing)Biocompatibility testing
    AgingStable performance over time(Implied by Accelerated aging)Accelerated aging testing

    Information on AI-Specific Study Elements (Not Applicable to this Document):

    The provided document is an FDA 510(k) summary for a physical medical device (an injection needle), not an AI/ML-driven diagnostic or treatment device. Therefore, the following information is not present and not applicable to this type of submission:

    1. Sample size used for the test set and the data provenance: Not applicable. There is no "test set" in the context of an AI algorithm. The device itself undergoes performance and safety testing.
    2. Number of experts used to establish the ground truth for the test set and the qualifications of those experts: Not applicable. There is no "ground truth" established by experts for a physical injection needle in this context.
    3. Adjudication method (e.g. 2+1, 3+1, none) for the test set: Not applicable.
    4. If a multi-reader multi-case (MRMC) comparative effectiveness study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance: Not applicable. This device does not involve human readers interpreting images with or without AI assistance.
    5. If a standalone (i.e. algorithm only without human-in-the-loop performance) was done: Not applicable. There is no algorithm.
    6. The type of ground truth used (expert consensus, pathology, outcomes data, etc.): Not applicable.
    7. The sample size for the training set: Not applicable. There is no AI model to train.
    8. How the ground truth for the training set was established: Not applicable.

    Summary of Relevant Information from the Document:

    • Device: Injection Needle (K150434)
    • Manufacturer: Micro-Tech (Nanjing) CO., Ltd.
    • Predicate Device: Injectra Injection Needle (K061222)
    • Regulatory Pathway: 510(k) for substantial equivalence.
    • Testing Performed: Biocompatibility, accelerated aging, performance, and sterilization validation testing. These tests demonstrated that the device is safe and effective for its intended use and supports its substantial equivalence to the predicate device.
    • Substantial Equivalence Conclusion: The manufacturer believes the proposed device is substantially equivalent to the predicate device, citing similarities in materials, intended use, function, and overall design. They acknowledge slight differences in needle length and working length, and minor differences in wording for indications for use, but state these differences do not raise new issues of safety or effectiveness.
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