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510(k) Data Aggregation

    K Number
    K120270
    Date Cleared
    2012-03-26

    (56 days)

    Product Code
    Regulation Number
    888.3070
    AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
    Intended Use

    VENUS Spinal Fixation System is non-cervical spinal fixation devices intended for use as posterior pedicle screw fixation systems (T1-S2/ilium), or as an anterolateral fixation system (T8-L5). All components in the system are limited to skeletally mature patients. These devices are indicated as an adjunct to fusion for all of the following indications regardless of the intended use:

    • degenerative disc disease (defined as discogenic back pain with degeneration of the disc confirmed by history and radiographic studies);
    • spondylolisthesis;
    • trauma (i.e., fracture or dislocation);
    • deformities or curvatures (i.e., scoliosis, kyphosis, and/or lordosis); .
    • tumor;
    • stenosis, and
    • failed previous fusion (pseudoarthrosis)

    The VENUS Spinal Fixation System is a pedicle screw system indicated for the treatment of severe spondylolisthesis (Grade 3 and 4) of the L5-S1 vertebra in skeletally mature patients receiving fusion by autogenous bone graft having implants attached to the lumbar and sacral spine (L3 to sacrum) with removal of the implants after the attainment of a solid fusion.

    In addition, the VENUS Spinal Fixation System is intended to provide immobilization and stabilization of spinal segments in skeletally mature patients as an adjunct to fusion in the treatment of the following acute and chronic instabilities or deformities of the thoracic, lumbar and sacral spine: degenerative spondylolisthesis with objective evidence of neurological impairment, fracture, dislocation, scoliosis, spinal tumor and failed previous fusion (pseudoarthrosis).

    Device Description

    This system is comprised of screws, set screws, rods, crosslink and connectors. The components of this system are manufactured of Titanium alloy (Titanium-6Aluminum-4 Vanadium ELI, per ASTM F136) and CoCrMo alloy (Cobalt-28Chromium-6Molybdenum, per ASTM F1537). The screws are available from 4.0 to 8.5mm diameters with lengths ranging from 20-150mm.

    AI/ML Overview

    This document describes the design and testing of the VENUS Spinal Fixation System, a non-cervical spinal fixation device.

    1. Table of Acceptance Criteria and Reported Device Performance

    TestAcceptance Criteria (Implicit)Reported Device Performance
    Static Compression Bending (ASTM F1717-10)Performance must be equivalent to predicate devices.The VENUS Spinal Fixation system performs equivalently to the predicates in static compression bending.
    Static Torsion (ASTM F1717-10)Performance must be equivalent to predicate devices.The VENUS Spinal Fixation system performs equivalently to the predicates in static torsion.
    Dynamic Compression Bending (ASTM F1717-10)Performance must be equivalent to predicate devices.The VENUS Spinal Fixation system performs equivalently to the predicates in dynamic compression bending.
    Gripping-Push Down (ASTM F1798)Performance must be equivalent to predicate devices.The VENUS Spinal Fixation system performs equivalently to the predicates in gripping-push down.

    Note: The document explicitly states that the acceptance criterion for all performance tests is "equivalent to the predicates." The specific numerical or qualitative thresholds for this equivalence are not provided in this summary but would be detailed in the full test reports.

    2. Sample Size and Data Provenance for Test Set

    • Sample Size: Not explicitly stated for each test. The document refers to "bench testing results," implying that multiple samples of the VENUS Spinal Fixation System components were subjected to each test.
    • Data Provenance: The tests are "bench testing" conducted by L&K BIOMED, Co., Ltd. The country of origin for the testing would be South Korea, where L&K BIOMED is located. The data is prospective, generated specifically for this 510(k) submission.

    3. Number of Experts and Qualifications for Ground Truth of Test Set

    This section is not applicable as the provided documentation describes a medical device (spinal fixation system) and its mechanical performance testing, not an AI/diagnostic device that would require expert-established ground truth for a test set. The "ground truth" here is the physical measurement of mechanical properties.

    4. Adjudication Method for Test Set

    This section is not applicable for the same reasons as point 3. Mechanical test results do not typically involve adjudication.

    5. Multi-Reader Multi-Case (MRMC) Comparative Effectiveness Study

    This section is not applicable as the provided documentation describes a medical device (spinal fixation system) and its mechanical performance testing, not an AI or diagnostic device that would involve human readers or MRMC studies.

    6. Standalone (i.e., algorithm only without human-in-the-loop performance) Study

    This section is not applicable as the provided documentation describes a medical device (spinal fixation system) and its mechanical performance testing, not an AI or algorithm-based device.

    7. Type of Ground Truth Used

    The ground truth used for performance evaluation is based on standardized mechanical testing results (e.g., measurements of strength, stiffness, and fatigue performance) as per established ASTM standards (F1717-10 and F1798). The "ground truth" performance is then compared to that of legally marketed predicate devices.

    8. Sample Size for the Training Set

    This section is not applicable as the provided documentation describes a medical device (spinal fixation system) and its mechanical performance testing, not a machine learning or AI device that would have a training set.

    9. How the Ground Truth for the Training Set Was Established

    This section is not applicable for the same reasons as point 8.

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