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510(k) Data Aggregation

    K Number
    K100421
    Date Cleared
    2010-09-27

    (223 days)

    Product Code
    Regulation Number
    880.6250
    Reference & Predicate Devices
    Predicate For
    N/A
    AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
    Intended Use

    Powder free vinyl patient examination glove is a non-sterile disposable device intended for medical purposes that is worn on the examiner's hand or finger to prevent contamination between patient and examiner.

    Device Description

    powder free vinyl patient examination gloves, Clear(non-colored) that meets all of the requirements of ASTM standard D 5250-06.

    AI/ML Overview

    Here's a breakdown of the acceptance criteria and study information based on the provided text, structured to answer your questions:

    Acceptance Criteria and Device Performance

    1. Table of Acceptance Criteria and Reported Device Performance

    CharacteristicsAcceptance Criteria (Standard)Reported Device Performance
    DimensionASTM standard D 5250-06Meets
    Physical PropertiesASTM standard D 5250-06Meets
    Freedom from pinholes21 CFR 800.20Meets
    Powder ResidualASTM standard D 5250-06 and D6124-06<2mg/glove
    Biocompatibility (Primary Skin Irritation)Primary Skin Irritation in rabbitsPasses (Not a Primary Skin Irritation)
    Biocompatibility (Dermal Sensitization)Dermal sensitization in the guinea pigPasses (Not a Dermal Sensitization)

    2. Sample size used for the test set and the data provenance

    The document does not specify a distinct "test set" sample size or data provenance (e.g., country of origin, retrospective/prospective) in the context of device performance or clinical studies. The performance is reported against established standards without detailing the specific methodology or a separate test dataset used to achieve these "Meets" or "Passes" statements.

    3. Number of experts used to establish the ground truth for the test set and the qualifications of those experts

    Not applicable. The document does not describe the use of experts to establish ground truth for a test set in the context of this device's performance evaluation. The evaluation relies on meeting established ASTM and CFR standards, which are objective measurements.

    4. Adjudication method for the test set

    Not applicable. There is no mention of a test set requiring adjudication in the context of this submission. The device's performance is gauged against pre-defined, objective standards.

    5. If a multi reader multi case (MRMC) comparative effectiveness study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

    Not applicable. This device is a patient examination glove, not an AI-powered diagnostic or assistive device. Therefore, MRMC studies are not relevant.

    6. If a standalone (i.e. algorithm only without human-in-the loop performance) was done

    Not applicable. This device is a patient examination glove and does not involve any algorithm or AI component.

    7. The type of ground truth used

    The "ground truth" for the device's performance is based on established industry standards and regulatory requirements. Specifically:

    • ASTM standard D 5250-06 for dimensions and physical properties.
    • 21 CFR 800.20 for freedom from pinholes.
    • ASTM standard D 5250-06 and D6124-06 for powder residual.
    • ISO10993-10 for biocompatibility (Primary Skin Irritation and Dermal Sensitization).
      These are objective, measurable criteria, not expert consensus, pathology, or outcomes data in the typical sense of a clinical study for complex medical devices.

    8. The sample size for the training set

    Not applicable. The document does not describe any "training set" as this is a medical device (patient examination glove) and not an AI or machine learning model.

    9. How the ground truth for the training set was established

    Not applicable. There is no training set involved with this device.

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