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510(k) Data Aggregation

    K Number
    K121415
    Date Cleared
    2012-09-05

    (117 days)

    Product Code
    Regulation Number
    870.4875
    Reference & Predicate Devices
    Predicate For
    N/A
    AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
    Intended Use

    This device is intended for remote endarterectomy of peripheral blood vessels during vascular reconstruction.

    Device Description

    The MollRing MultiTASC is a single use, sterile and disposable device designed for vascular surgeons use during remote endarterectomy procedures for the facilitation of dissecting, cutting and removing atheromatous plaque core within the peripheral vascular system.

    The Subject Device is a fixed, circumferential, blunt-edged, sterile, single use cutting tool. It consists of two stainless steel coaxial metal rings (proximal and distal rings) which are connected by a stainless steel rod and hypo tube system. The modular rod and hypo tube system connects to a plastic operator's handle with selective positions for ring alignment (cutting/dissecting phase).

    The device is introduced over the proximal end of the atheromatous plaque core of a peripheral vascular vessel. With the two stainless steel coaxial metal rings in "alignment position", they are advanced to the distal end of the plaque core. As the device transverses the vessel it acts as a conventional circumferential dissection ring stripper, removing the plaque core to the distal endpoint. The device is then switched via the operator handle to "un-alignment position", which spreads the distal and proximal rings, thus cutting and securing the plaque core. Once secured, the device is withdrawn, facilitating the core removal.

    AI/ML Overview

    Based on the K121415 document, here's a breakdown of the acceptance criteria and the study conducted:

    This document is a 510(k) summary for a medical device (MollRing MultiTASC Dissection/Transection Device), not a study report for an AI/ML device. Therefore, the questions related to AI/ML specific aspects (like expert consensus for ground truth, sample sizes for training/test sets, MRMC studies, standalone performance, and human reader improvement with AI) are not applicable to this document. This submission focuses on non-clinical performance and substantial equivalence to a predicate device.


    1. Table of Acceptance Criteria and Reported Device Performance

    Acceptance Criteria (Product Design Specifications)Reported Device Performance
    Dimensional VerificationMet product design specifications
    Ring Weld StrengthMet product design specifications
    Weld Flex StrengthMet product design specifications
    Inner and Outer Hypo Tube Bond StrengthMet product design specifications
    Coupler Attachment StrengthMet product design specifications
    T-Handle Pull ForceMet product design specifications
    T-Handle Torsion StrengthMet product design specifications
    Device ActuationMet product design specifications
    Shaft BendMet product design specifications
    Ring Cutting ForceMet product design specifications
    Compression FatigueMet product design specifications
    Shelf Life TestingMet product design specifications
    Sterilization (Ethylene Oxide)Validated according to ANSI/AAMI/ISO 11135-1:2007
    BiocompatibilityMet ISO 10993 guidelines for an externally communicating device with limited contact duration (<24 hours) in circulating blood

    2. Sample size used for the test set and the data provenance (e.g. country of origin of the data, retrospective or prospective)

    This document does not specify sample sizes for the test sets for the performance tests listed. These are non-clinical, bench-top engineering tests, not clinical trials with patient data. Therefore, data provenance in terms of country of origin or retrospective/prospective is not applicable.


    3. Number of experts used to establish the ground truth for the test set and the qualifications of those experts (e.g. radiologist with 10 years of experience)

    Not applicable. This document describes non-clinical, engineering performance tests. Ground truth in the context of expert review for clinical data is not relevant here. The "ground truth" for these tests would be the established engineering specifications themselves, measured by calibrated equipment.


    4. Adjudication method (e.g. 2+1, 3+1, none) for the test set

    Not applicable. Adjudication methods are typically for clinical studies involving human interpretation or subjective assessments. These are objective engineering measurements.


    5. If a multi reader multi case (MRMC) comparative effectiveness study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

    No. This is a medical device (surgical tool), not an AI-powered diagnostic or assistive device. MRMC studies, AI improvement, and human readers are not relevant.


    6. If a standalone (i.e. algorithm only without human-in-the loop performance) was done

    No. This is a physical surgical device, not an algorithm. Standalone algorithm performance is not applicable.


    7. The type of ground truth used (expert concensus, pathology, outcomes data, etc)

    For the performance testing/non-clinical testing, the "ground truth" is the pre-defined product design specifications and relevant international standards (e.g., ANSI/AAMI/ISO 11135-1:2007 for sterilization, ISO 10993 for biocompatibility). The tests verify that the device's physical properties and functionality meet these objective engineering and safety standards.


    8. The sample size for the training set

    Not applicable. This is a traditional medical device submission, not an AI/ML device, so there is no "training set."


    9. How the ground truth for the training set was established

    Not applicable. As there is no training set for an AI/ML model, the ground truth establishment method for it is irrelevant to this submission.

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