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510(k) Data Aggregation

    K Number
    K030464
    Date Cleared
    2003-03-14

    (30 days)

    Product Code
    Regulation Number
    868.1840
    Reference & Predicate Devices
    Predicate For
    AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
    Intended Use

    The GEM is intended to be used for diagnostic use in the treatment of pulmonary illnesses with an intended use and indication for use as a configurable, non-invasive pulmonary function tester (PFT) testing system.. The GEM is indicated for use in: pulmonary function testing.
    The Collins GEM (Gas Exchange Module) is a Pulmonary Function Test System. is intended as a configurable, non-invasive pulmonary function tester (PFT). These tests are suitable for both pediatric and adult patient testing. Compatible with the Collins' Body Plethysmograph as an optional module.

    Device Description

    The GEM (Gas Exchange Module) is a configurable, non-invasive pulmonary function tester (PFT) testing system. It includes a spirometer (pneumotach), gas analyzers (infrared for CO, CO2, CH4 and electrochemical for O2), and associated electronics.

    AI/ML Overview

    The Collins GEM (Gas Exchange Module) is a diagnostic spirometer intended for use in pulmonary function testing.

    Here is a summary of the acceptance criteria and the study information based on the provided text:

    1. Table of Acceptance Criteria and Reported Device Performance:

    Feature/ParameterAcceptance Criteria (Standard/Reference)Reported Device Performance
    Spirometer Metrics
    Resistance (Pneumotach)< 1.4 cmH2O/L/Sec @ 14 L/Sec< 1.4 cmH2O/L/Sec @ 14 L/Sec (from pneumotach description)
    Volume Accuracy+/- 3%+/- 3%
    Resistance (GemTach - separate component)< 0.5 cmH2O/L/Sec @ 14 L/Sec< 0.5 cmH2O/L/Sec @ 14 L/Sec
    Accuracy (GemTach)+/- 3%+/- 3%
    Flow Range (GemTach)Not explicitly stated as acceptance criteria, but given as specification+/- 15 L/Sec
    Gas Analyzers Metrics
    Response (Multi-Gas: CO, CO2, CH4)Not explicitly stated as acceptance criteria, but "fast-response" mentioned and monitored during production with pass/fail criteria identical to CPL< 100 ms
    Accuracy (Multi-Gas: CO, CO2, CH4)Not explicitly stated as acceptance criteria, but monitored during production with pass/fail criteria identical to CPL1%
    Linearity (Multi-Gas: CO, CO2, CH4)Not explicitly stated as acceptance criteria, but monitored during production with pass/fail criteria identical to CPL< 1%
    Noise (Multi-Gas: CO, CO2, CH4)Not explicitly stated as acceptance criteria, but monitored during production with pass/fail criteria identical to CPL< 1% full scale
    Response (Oxygen)Not explicitly stated as acceptance criteria, but "fast-response" mentioned and monitored during production with pass/fail criteria identical to CPL80 ms
    Accuracy (Oxygen)Not explicitly stated as acceptance criteria, but monitored during production with pass/fail criteria identical to CPL1%
    General Compliance/Performance
    Electrical SafetyUL 2601-1, EN 60601-1, IEC 60601-1-1, CSA 22.2 No. 1Conforms as stated implicitly by listing standards
    Emissions and ImmunityIEC 60601-1-2Conforms as stated implicitly by listing standards
    Spirometry PerformanceATS American Thoracic Society Standardization of Spirometry 1994 UpdateConforms as stated implicitly by listing standards
    Single-breath Carbon Monoxide Diffusing CapacityATS American Thoracic Society Recommendations for a Standard Technique - 1995 UpdateConforms as stated implicitly by listing standards

    2. Sample Size Used for the Test Set and Data Provenance:

    The provided document describes the technical specifications and adherence to recognized standards for the Collins GEM device. It does not contain information about a specific "test set" in the context of a clinical performance study with human subjects or a defined dataset. The performance metrics listed are technical specifications that would be verified through engineering and calibration tests, not typically a clinical test set with patient data.

    3. Number of Experts Used to Establish Ground Truth for the Test Set and Qualifications:

    Not applicable. The document does not describe a study involving expert-established ground truth for a test set. The validation appears to be based on adherence to engineering specifications and industry standards.

    4. Adjudication Method for the Test Set:

    Not applicable. The document does not describe a study involving adjudication of a test set.

    5. Multi-Reader Multi-Case (MRMC) Comparative Effectiveness Study:

    No. The document does not mention a multi-reader multi-case (MRMC) comparative effectiveness study, nor does it discuss human reader improvement with or without AI assistance. This device is a diagnostic instrument, not an AI-based interpretation tool.

    6. Standalone (Algorithm Only) Performance Study:

    Yes, in the sense that the device's technical specifications and performance are evaluated independently against established standards and calibration procedures. The description mentions "production, step responses, linearity, noise, and drift parameters are monitored, and the pass/fail criteria are identical to that of the CPL." This implies standalone testing of the device's components against predefined thresholds.

    7. Type of Ground Truth Used:

    The "ground truth" for the device's technical specifications is rooted in:

    • Industry Standards: Performance guidelines set by organizations like the American Thoracic Society (ATS) for spirometry and carbon monoxide diffusing capacity.
    • Calibration Standards: Use of known volume displacement devices (e.g., 3-liter syringe) and known gas concentrations for calibration.
    • Engineering Specifications: Internal design and performance thresholds for electrical, mechanical, and analytical components.

    8. Sample Size for the Training Set:

    Not applicable. This document describes a medical device, not an AI model, so there is no concept of a "training set" in the context of machine learning.

    9. How the Ground Truth for the Training Set Was Established:

    Not applicable. As there is no training set for an AI model, this question is not relevant to the provided text.

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