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510(k) Data Aggregation

    K Number
    K200156
    Device Name
    Bright Low Flow
    Manufacturer
    Date Cleared
    2020-10-27

    (279 days)

    Product Code
    Regulation Number
    872.3690
    Panel
    Dental
    Reference & Predicate Devices
    Predicate For
    N/A
    AI/MLSaMDIVD (In Vitro Diagnostic)TherapeuticDiagnosticis PCCP AuthorizedThirdpartyExpeditedreview
    Intended Use
    1. Class I, III, V (non-stress area, minimally invasive restoration)
    2. Composite resin repair
    Device Description

    Bright Flow is a light-cured flowable composite resin. It comprises two different types of flowability (Low Flow and High Flow) and 9 shades depending on the intended use, which enables aesthetic and durable outcomes for anterior and posterior composite restorations.

    AI/ML Overview

    This document is a 510(k) summary for the medical device "Bright Low Flow", a light-cured flowable composite resin manufactured by GENOSS Co., Ltd. It declares that the device is substantially equivalent to a predicate device (K091388 G-aenial Universal Flo) and provides performance data to support this claim.

    Here's a breakdown of the requested information based on the provided text:

    1. Table of Acceptance Criteria and Reported Device Performance

    The document presents two tables related to performance criteria: Biocompatibility and Performance Bench Testing.

    Biocompatibility Acceptance Criteria and Performance:

    No.TestMethodAcceptance criteriaP/F (Result)
    1CytotoxicityISO 10993-5None cytotoxicityPass
    2IrritationISO 10993-10None oral irritationPass
    3SensitizationISO 10993-10None sensitizationPass
    4Acute systemic toxicityISO 10993-11None systemic toxicityPass
    5GenotoxicityISO 10993-3None genotoxicityPass
    6ImplantationISO 10993-6BiocompatiblePass
    7Chronic toxicityISO 10993-11No chronic toxicityPass

    Performance Bench Testing Acceptance Criteria and Performance:

    No.ItemsMethodAcceptance CriteriaResult
    1VisualISO 4049No impurities and No specific changesNo impurities and No specific changes
    2CapacityISO 4049Capacity error of; Standard Capacity < ±5%Size error of; Standard Size < ±5% H 0.43%, Ø 0.03%
    3PackageISO 4049No damageNo damage
    4Sensitivity to Ambient LightISO 4049Must be physically uniformUniformity
    5Depth of CureISO 4049More than 1.5 mmAverage: 2.9 mm
    6ShadeISO 4049Must be shade uniformUniformity
    7Color StabilityISO 4049Color should be stableStable
    8Flexural StrengthISO 4049More than 80 MPaAverage: 142 MPa
    9Water SorptionISO 4049Less than 40 µg/mm3Average: 23 µg/mm3
    10SolubilityISO 4049Less than 7.5 µg/mm3Average: 0.9 µg/mm3
    11Radio-opacityISO 4049More than Al≥ Al (1.81)

    2. Sample Size Used for the Test Set and Data Provenance

    The document does not explicitly state the sample sizes used for each of the biocompatibility and performance bench tests. However, the tests are identified by their ISO standard methods (e.g., ISO 10993-5, ISO 4049), implying that the testing was conducted according to these internationally recognized standards, which typically define appropriate sample sizes.

    Data Provenance: The document indicates that the submitter is "GENOSS Co., Ltd." located in "Suwon-si, Gyeonggi-do, Korea." This suggests the data was generated in South Korea, or at least commissioned by a South Korean company. The tests are referred to as "Biocompatibility testing on the proposed Bright Low Flow has been completed" and "The proposed Bright Low Flow was evaluated using the following performance bench testing," implying these are prospective tests performed on the device itself for this submission.

    3. Number of Experts Used to Establish the Ground Truth for the Test Set and Qualifications of Those Experts

    This information is not provided in the document. The tests performed are laboratory-based physical and chemical property evaluations or biological assays (biocompatibility) rather than interpretations requiring human expert consensus on a test set.

    4. Adjudication Method for the Test Set

    This information is not applicable as the tests are objective, laboratory-based measurements or biological assays, not interpretations requiring adjudication.

    5. If a Multi Reader Multi Case (MRMC) Comparative Effectiveness Study was done, If so, what was the effect size of how much human readers improve with AI vs without AI assistance

    This information is not applicable. The device is a "light-cured flowable composite resin" (dental material), not an AI diagnostic or assistive tool.

    6. If a Standalone (i.e. algorithm only without human-in-the-loop performance) was done

    This information is not applicable. The device is a dental material, not an algorithm.

    7. The Type of Ground Truth Used

    For the biocompatibility tests, the "ground truth" is based on the biological response observed in the specific assays according to the ISO 10993 standards (e.g., cell viability for cytotoxicity, skin reaction for irritation, systemic effects for acute systemic toxicity).

    For the performance bench tests, the "ground truth" is the quantitative measurement of the physical/chemical properties of the material (e.g., depth of cure in mm, flexural strength in MPa, water sorption in µg/mm3) as determined by the specified ISO 4049 standard methods. This represents direct measurement of inherent material properties.

    8. The Sample Size for the Training Set

    This information is not applicable. As a dental material, there is no "training set" in the context of machine learning or AI models. The device's properties are inherent to its formulation and manufacturing process, evaluated through scientific testing.

    9. How the Ground Truth for the Training Set Was Established

    This information is not applicable for the reasons stated in point 8.

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