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Optiflux® Enexa™ dialyzers are intended for patients with acute kidney injury or chronic kidney disease when conservative therapy is judged to be inadequate.

The Optiflux Enexa F500 dialyzer is a high-flux, single-use, e-beam sterilized hemodialyzer that contains the additive Endexo SMM1 blended into the fiber. The dialyzer is provided blood pathway sterile and non-pyrogenic. The membrane surface area is 1.5 m². The Optiflux Enexa F500 dialyzer is a high-flux, sterile device designed for single-use in acute and chronic hemodialysis. The dialyzer is configured to connect to a bloodline set which connects to a patient's vascular access system when used with a hemodialysis machine equipped with ultrafiltration control. During hemodialysis, blood is pumped from the patient's body through an extracorporeal circuit, one component of which is the dialyzer. The dialyzer contains a semi-permeable membrane that allows for diffusion and/or ultrafiltration to transport toxins and excess fluid from the blood compartment (fiber lumen) to the dialysate compartment. Dialyzers utilize a counter-current flow in which dialysate and blood flow in opposite directions in the dialyzer. The counter-current flow maintains the concentration gradient across the membrane for waste and fluid removal.